未登录 A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation TRIM21-based bioPROTAC突出了HuR降解的治疗益处 Fletcher, Alice; Clift, Dean; de Vries, Emma; Martinez Cuesta, Sergio; Malcolm, Timothy; Meghini, Francesco; Chaerkady, Raghothama; Wang, Junmin; Chiang, Abby; Weng, Shao Huan Samuel; Tart, Jonathan; Wong, Edmond; Donohoe, Gerard; Rawlins, Philip; Gordon, Euan; Taylor, Jonathan D.; James, Leo; Hunt, James 分享 收藏
Comparative systeomics to elucidate physiological differences between CHO and SP2/0 cell lines Demirhan, Deniz; Kumar, Amit; Zhu, Jie; Poulsen, Pi Camilla; Majewska, Natalia, I; Sebastian, Yinong; Chaerkady, Raghothama; Yu, Wen; Zhu, Wei; Zhuang, Li; Shah, Punit; Lekstrom, Kristen; Cole, Robert N.; Zhang, Hui; Betenbaugh, Michael J.; Bowen, Michael A. 分享 收藏
Mitochondrial membrane potential-enriched CHO host: a novel and powerful tool for improving biomanufacturing capability Chakrabarti, Lina; Chaerkady, Raghothama; Wang, Junmin; Weng, Shao Huan Samuel; Wang, Chunlei; Qian, Chen; Cazares, Lisa; Hess, Sonja; Amaya, Peter; Zhu, Jie; Hatton, Diane 分享 收藏
COMPREHENSIVE MULTIOMICS ANALYSIS DEMONSTRATES SURFACTANT DYSREGULATION IN COPD Hristova, V.; Watson, A.; Glover, M.; Wang, J.; Angermann, B.; Ashenden, S.; Bornot, A.; Burke, H.; Cellura, D.; Chaerkady, R.; Freeman, A.; Mackay, A.; Muthas, D.; Novick, S.; Oberg, L.; Ostridge, K.; Platt, A.; Postle, A. D.; Spalluto, C. M.; Yu, W.; Hess, S.; Staples, K. J.; Wilkinson., T. M. A. 分享 收藏
Resistance to Pyrrolobenzodiazepine Dimers Is Associated with SLFN11 Downregulation and Can Be Reversed through Inhibition of ATR Mao, Shenlan; Chaerkady, Raghothama; Yu, Wen; D'Angelo, Gina; Garcia, Andrew; Chen, Hong; Barrett, Allison M.; Phipps, Sandrina; Fleming, Ryan; Hess, Sonja; Koopmann, Jens-Oliver; Dimasi, Nazzareno; Wilson, Susan; Pugh, Kathryn; Cook, Kimberly; Masterson, Luke A.; Gao, Changshou; Wu, Herren; Herbst, Ronald; Howard, Philip W.; Tice, David A.; Cobbold, Mark; Harper, Jay 分享 收藏
Development of a Parallel Reaction Monitoring Mass Spectrometry Assay for the Detection of SARS-CoV-2 Spike Glycoprotein and Nucleoprotein Cazares, Lisa H.; Chaerkady, Raghothama; Weng, Shao Huan Samuel; Boo, Chelsea C.; Cimbro, Raffaello; Hsu, Hsiang-En; Rajan, Sarav; Dall'Acqua, William; Clarke, Lori; Ren, Kuishu; McTamney, Patrick; Kallewaard-LeLay, Nicole; Ghaedi, Mahboobe; Ikeda, Yasuhiro; Hess, Sonja 分享 收藏
Proteogenomic Annotation of Chinese Hamsters Reveals Extensive Novel Translation Events and Endogenous Retroviral Elements Li, Shangzhong; Cha, Seong Won; Heffner, Kelly; Hizal, Deniz Baycin; Bowen, Michael A.; Chaerkady, Raghothama; Cole, Robert N.; Tejwani, Vijay; Kaushik, Prashant; Henry, Michael; Meleady, Paula; Sharfstein, Susan T.; Betenbaugh, Michael J.; Bafna, Vineet; Lewis, Nathan E. 分享 收藏
Staphylococcus aureus drives expansion of low-density neutrophils in diabetic mice Cohen, Taylor S.; Takahashi, Virginia; Bonnell, Jessica; Tovchigrechko, Andrey; Chaerkady, Raghothama; Yu, Wen; Jones-Nelson, Omari; Lee, Young; Raja, Rajiv; Hess, Sonja; Stover, C. Kendall; Worthington, John J.; Travis, Mark A.; Sellman, Bret R. 分享 收藏
Evidence for a direct link between PAD4-mediated citrullination and the oxidative burst in human neutrophils Zhou, Yebin; An, Ling-Ling; Chaerkady, Raghothama; Mittereder, Nanette; Clarke, Lori; Cohen, Taylor S.; Chen, Bo; Hess, Sonja; Sims, Gary P.; Mustelin, Tomas 分享 收藏
A novel bicistronic gene design couples stable cell line selection with a fucose switch in a designer CHO host to produce native and afucosylated glycoform antibodies Roy, Gargi; Martin, Tom; Barnes, Arnita; Wang, Jihong; Jimenez, Rod Brian; Rice, Megan; Li, Lina; Feng, Hui; Zhang, Shu; Chaerkady, Raghothama; Wu, Herren; Marelli, Marcello; Hatton, Diane; Zhu, Jie; Bowen, Michael A. 分享 收藏
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USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1 Li, Zengxia; Cheng, Zhao; Raghothama, Chaerkady; Cui, Zhaomeng; Liu, Kaiyu; Li, Xiaojing; Jiang, Chenxiao; Jiang, Wei; Tan, Minjia; Ni, Xiaohua; Pandey, Akhilesh; Liu, Jun O.; Dang, Yongjun 分享 收藏
Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure Of PAD4 by Neutrophils Zhou, Yebin; Chen, Bo; Mittereder, Nanette; Chaerkady, Raghothama; Strain, Martin; An, Ling-Ling; Rahman, Saifur; Ma, Wenting; Low, Choon Pei; Chan, Denice; Neal, Frances; Bingham, Clifton O., III; Sampson, Kevon; Darrah, Erika; Siegel, Richard M.; Hasni, Sarfaraz; Andrade, Felipe; Vousden, Katherine A.; Mustelin, Tomas; Sims, Gary P. 分享 收藏
Lessons from the Hamster: Cricetulus griseus Tissue and CHO Cell Line Proteome Comparison 仓鼠的经验教训: griseus组织和CHO细胞系蛋白质组比较 Heffner, Kelley M.; Hizal, Deniz Baycin; Yerganian, George S.; Kumar, Amit; Can, Ozge; O'Meally, Robert; Cole, Robert; Chaerkady, Raghothama; Wu, Herren; Bowen, Michael A.; Betenbaugh, Michael J. 分享 收藏
Statistical Models for the Analysis of Isobaric Tags Multiplexed Quantitative Proteomics D'Angelo, Gina; Chaerkady, Raghothama; Yu, Wen; Hizal, Deniz Baycin; Hess, Sonja; Zhao, Wei; Lekstrom, Kristen; Guo, Xiang; White, Wendy I.; Roskos, Lorin; Bowen, Michael A.; Yang, Harry 分享 收藏
Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats Ratovitski, Tamara; O'Meally, Robert N.; Jiang, Mali; Chaerkady, Raghothama; Chighladze, Ekaterine; Stewart, Jacqueline C.; Wang, Xiaofang; Arbez, Nicolas; Roby, Elaine; Alexandris, Athanasios; Duan, Wenzhen; Vijayvargia, Ravi; Seong, Ihn Sik; Lavery, Daniel J.; Cole, Robert N.; Ross, Christopher A. 分享 收藏
Tumor cells treated with a PBD-based antibody-drug conjugate targeting 5T4 develop acquired resistance due to 5T4 down-regulation and response to alternate therapeutics Mao, Shenlan; Garcia, Andrew; Chen, Tracy; Chaerkady, Raghothama; Marreno, Allison; Zhong, Helen; Toader, Dorin; Dimasi, Nazzareno; Kennedy, Maureen; Howard, Philip; Gao, Changshou; Wu, Herren; Herbst, Ronald; Tice, David; Harper, Jay 分享 收藏
Quantitative Tyrosine Phosphoproteomics of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor-treated Lung Adenocarcinoma Cells Reveals Potential Novel Biomarkers of Therapeutic Response Zhang, Xu; Maity, Tapan; Kashyap, Manoj K.; Bansal, Mukesh; Venugopalan, Abhilash; Singh, Sahib; Awasthi, Shivangi; Marimuthu, Arivusudar; Jacob, Harrys Kishore Charles; Belkina, Natalya; Pitts, Stephanie; Cultraro, Constance M.; Gao, Shaojian; Kirkali, Guldal; Biswas, Romi; Chaerkady, Raghothama; Califano, Andrea; Pandey, Akhilesh; Guha, Udayan 分享 收藏
Quantitative Proteomic Analysis Reveals Similarities between Huntington's Disease (HD) and Huntington's Disease-Like 2 (HDL2) Human Brains Ratovitski, Tamara; Chaerkady, Raghothama; Kammers, Kai; Stewart, Jacqueline C.; Zavala, Anialak; Pletnikova, Olga; Troncoso, Juan C.; Rudnicki, Dobrila D.; Margolis, Russell L.; Cole, Robert N.; Ross, Christopher A. 分享 收藏
FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1 Khan, Shahid Y.; Vasanth, Shivakumar; Kabir, Firoz; Gottsch, John D.; Khan, Arif O.; Chaerkady, Raghothama; Lee, Mei-Chong W.; Leitch, Carmen C.; Ma, Zhiwei; Laux, Julie; Villasmil, Rafael; Khan, Shaheen N.; Riazuddin, Sheikh; Akram, Javed; Cole, Robert N.; Talbot, C. Conover; Pourmand, Nader; Zaghloul, Norann A.; Hejtmancik, J. Fielding; Riazuddin, S. Amer 分享 收藏