Patrick Aebischer - Publications, H-index & Citations

Patrick Aebischer

swiss federal institutes of technology domain

103H指数

460论文数

3.0W被引数

收录论文 87

发表时间

Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults 尿石素A在中年成年人的随机试验中改善肌肉力量，运动表现和线粒体健康的生物标志物

CELL REPORTS MEDICINE

IF10.6

2022-05-01

OAAI

Singh, Anurag; D'Amico, Davide; Andreux, Penelope A.; Fouassier, Andreane M.; Blanco-Bose, William; Evans, Mal; Aebischer, Patrick; Auwerx, Johan; Rinsch, Chris

Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults A Randomized Clinical Trial

JAMA NETWORK OPEN

IF9.7

2022-01-20

OAAI

Liu, Sophia; D'Amico, Davide; Shankland, Eric; Bhayana, Saakshi; Garcia, Jose M.; Aebischer, Patrick; Rinsch, Chris; Singh, Anurag; Marcinek, David J.

Astrocyte-targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast-fatigable motor units in a mouse model of amyotrophic lateral sclerosis

GLIA

IF5.1

2022-01-03

OAAI

Rochat, Cylia; Bernard-Marissal, Nathalie; Kaellstig, Emma; Pradervand, Sylvain; Perrin, Florence E.; Aebischer, Patrick; Raoul, Cedric; Schneider, Bernard L.

Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population

European Journal of Clinical Nutrition

IF3.3

2021-06-11

OAAI

Singh, Anurag; D'Amico, Davide; Andreux, Penelope A.; Dunngalvin, Gillian; Kern, Timo; Blanco-Bose, William; Auwerx, Johan; Aebischer, Patrick; Rinsch, Chris

The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans 线粒体激活物尿石素A是安全的，并诱导改善人类线粒体和细胞健康的分子特征

NATURE METABOLISM

IF20.8

2019-06-14

352

PREAI

Andreux, Penelope A.; Blanco-Bose, William; Ryu, Dongryeol; Burdet, Frederic; Ibberson, Mark; Aebischer, Patrick; Auwerx, Johan; Singh, Anurag; Rinsch, Chris

Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

IF4.5

2018-02-05

OAAI

Lei, Hongxia; Dirren, Elisabeth; Poitry-Yamate, Carole; Schneider, Bernard L.; Gruetter, Rolf; Aebischer, Patrick

Modulating the catalytic activity of AMPK has neuroprotective effects against α-synuclein toxicity

MOLECULAR NEURODEGENERATION

IF17.5

2017-11-03

OAAI

Bobela, Wojciech; Nazeeruddin, Sameer; Knott, Graham; Aebischer, Patrick; Schneider, Bernard L.

Highlights of the Cell Transplantation Meeting at Montreux, March 1999

CELL TRANSPLANTATION

IF3.2

2017-06-22

PREAI

Rinsch, C; Schneider, BL; Aebischer, P

Evaluation of an intrathecal immune response in amyotrophic lateral sclerosis patients implanted with encapsulated genetically engineered xenogeneic cells

CELL TRANSPLANTATION

IF3.2

2017-06-22

OAAI

Zurn, AD; Henry, H; Schluep, M; Aubert, V; Winkel, L; Eilers, B; Bachmann, C; Aebischer, P

Parkin functionally interacts with PGC-1∝ to preserve mitochondria and protect dopaminergic neurons

HUMAN MOLECULAR GENETICS

IF3.2

2017-01-04

OAAI

Zheng, Lu; Bernard-Marissal, Nathalie; Moullan, Norman; D'Amico, Davide; Auwerx, Johan; Moore, Darren J.; Knott, Graham; Aebischer, Patrick; Schneider, Bernard L.

Urolithin A induces mitophagy and prolongs lifespan in C-elegans and increases muscle function in rodents

NATURE MEDICINE

IF50

2016-07-11

728

PREAI

Ryu, Dongryeol; Mouchiroud, Laurent; Andreux, Penelope A.; Katsyuba, Elena; Moullan, Norman; Nicolet-dit-Felix, Amandine A.; Williams, Evan G.; Jha, Pooja; Lo Sasso, Giuseppe; Huzard, Damien; Aebischer, Patrick; Sandi, Carmen; Rinsch, Chris; Auwerx, Johan

Use of a Bicistronic Vector to Silence SOD1 in Motoneurons and Astrocytes for the Treatment of Familial Amyotrophic Lateral Sclerosis

MOLECULAR THERAPY

IF12

2016-05-01

OAAI

Bobela-Aebischer, Julianne; Rochat, Cylia; Bernard-Marissal, Nathalie; Aebischer, Patrick; Schneider, Bernard L.

A subcutaneous cellular implant for passive immunization against amyloid-β reduces brain amyloid and tau pathologies

BRAIN

IF11.7

2016-03-08

OAAI

Lathuiliere, Aurelien; Laversenne, Vanessa; Astolfo, Alberto; Kopetzki, Erhard; Jacobsen, Helmut; Stampanoni, Marco; Bohrmann, Bernd; Schneider, Bernard L.; Aebischer, Patrick

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons 从星形胶质细胞到神经元的乳酸梯度的体内证据

CELL METABOLISM

IF30.9

2016-01-01

451

OAAI

Machler, Philipp; Wyss, Matthias T.; Elsayed, Maha; Stobart, Jillian; Gutierrez, Robin; von Faber-Castell, Alexandra; Kaelin, Vincens; Zuend, Marc; San Martin, Alejandro; Romero-Gomez, Ignacio; Baeza-Lehnert, Felipe; Lengacher, Sylvain; Schneider, Bernard L.; Aebischer, Patrick; Magistretti, Pierre J.; Felipe Barros, L.; Weber, Bruno

Tmc gene therapy restores auditory function in deaf mice

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2015-07-08

216

OAAI

Askew, Charles; Rochat, Cylia; Pan, Bifeng; Asai, Yukako; Ahmed, Hena; Child, Erin; Schneider, Bernard L.; Aebischer, Patrick; Holt, Jeffrey R.

SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY

IF3.9

2015-01-15

OAAI

Dirren, Elisabeth; Aebischer, Julianne; Rochat, Cylia; Towne, Christopher; Schneider, Bernard L.; Aebischer, Patrick

A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity

HUMAN MOLECULAR GENETICS

IF3.2

2014-05-02

OAAI

Dusonchet, Julien; Li, Hu; Guillily, Maria; Liu, Min; Stafa, Klodjan; Troletti, Claudio Derada; Boon, Joon Y.; Saha, Shamol; Glauser, Liliane; Mamais, Adamantios; Citro, Allison; Youmans, Katherine L.; Liu, LiQun; Schneider, Bernard L.; Aebischer, Patrick; Yue, Zhenyu; Bandopadhyay, Rina; Glicksman, Marcie A.; Moore, Darren J.; Collins, James J.; Wolozin, Benjamin

A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells

BIOMATERIALS

IF12.9

2014-01-01

OAAI

Lathuiliere, Aurelien; Cosson, Steffen; Lutolf, Matthias P.; Schneider, Bernard L.; Aebischer, Patrick

Neuronal Matrix Metalloproteinase-9 Is a Determinant of Selective Neurodegeneration

NEURON

IF15

2014-01-01

245

OAAI

Kaplan, Artem; Spiller, Krista J.; Towne, Christopher; Kanning, Kevin C.; Choe, Ginn T.; Geber, Adam; Akay, Turgay; Aebischer, Patrick; Henderson, Christopher E.

Genetic engineering of cell lines using lentiviral vectors to achieve antibody secretion following encapsulated implantation

BIOMATERIALS

IF12.9

2014-01-01

PREAI

Lathuiliere, Aurelien; Bohrmann, Bernd; Kopetzki, Erhard; Schweitzer, Christoph; Jacobsen, Helmut; Moniatte, Marc; Aebischer, Patrick; Schneider, Bernard L.

研究方向