未登录 Mammalian sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation Lombard, David B.; Alt, Frederick W.; Cheng, Hwei-Ling; Bunkenborg, Jakob; Streeper, Ryan S.; Mostoslavsky, Raul; Kim, Jennifer; Yancopoulos, George; Valenzuela, David; Murphy, Andrew; Yang, Yinhua; Chen, Yaohui; Hirschey, Matthew D.; Bronson, Roderick T.; Haigis, Marcia; Guarente, Leonard P.; Farese, Robert V., Jr.; Weissman, Sherman; Verdin, Eric; Schwer, Bjoern 分享 收藏
Production of large, defined genome modifications in rats by targeting rat embryonic stem cells Lee, Jeffrey; Wang, Jingjing; Ally, Roxanne; Trzaska, Sean; Hickey, Joseph; Mujica, Alejo; Miloscio, Lawrence; Mastaitis, Jason; Morse, Brian; Smith, Janell; Atanasio, Amanda; Chiao, Eric; Chen, Henry; Latuszek, Adrianna; Hu, Ying; Valenzuela, David; Romano, Carmelo; Zambrowicz, Brian; Auerbach, Wojtek 分享 收藏
ANGPTL4-v3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2 Perdiguero, Elisa Gomez; Liabotis-Fontugne, Athanasia; Durand, Melanie; Faye, Clement; Ricard-Blum, Sylvie; Simonutti, Manuel; Augustin, Sebastien; Robb, Bryan M.; Paques, Michel; Valenzuela, David M.; Murphy, Andrew J.; Yancopoulos, George D.; Thurston, Gavin; Galaup, Ariane; Monnot, Catherine; Germain, Stephane 分享 收藏
Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injury Subramanian, Balajikarthick; Sun, Hua; Yan, Paul; Charoonratana, Victoria T.; Higgs, Henry N.; Wang, Fang; Lai, Ka-Man V.; Valenzuela, David M.; Brown, Elizabeth J.; Schlondorff, Johannes S.; Pollak, Martin R. 分享 收藏
C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice Atanasio, Amanda; Decman, Vilma; White, Derek; Ramos, Meg; Ikiz, Burcin; Lee, Hoi-Ching; Siao, Chia-Jen; Brydges, Susannah; LaRosa, Elizabeth; Bai, Yu; Fury, Wen; Burfeind, Patricia; Zamfirova, Ralica; Warshaw, Gregg; Orengo, Jamie; Oyejide, Adelekan; Fralish, Michael; Auerbach, Wojtek; Poueymirou, William; Freudenberg, Jan; Gong, Guochun; Zambrowicz, Brian; Valenzuela, David; Yancopoulos, George; Murphy, Andrew; Thurston, Gavin; Lai, Ka-Man Venus 分享 收藏
Loss of SFRP4 Alters Body Size, Food Intake, and Energy Expenditure in Diet-Induced Obese Male Mice Mastaitis, Jason; Eckersdorff, Mark; Min, Soo; Xin, Yurong; Cavino, Katie; Aglione, Johnpaul; Okamoto, Haruka; Na, Erqian; Stitt, Trevor; Dominguez, Melissa G.; Schmahl, Jennifer P.; Lin, Calvin; Gale, Nicholas W.; Valenzuela, David M.; Murphy, Andrew J.; Yancopoulos, George D.; Gromada, Jesper 分享 收藏
Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys Okamoto, Haruka; Kim, Jinrang; Aglione, JohnPaul; Lee, Joseph; Cavino, Katie; Na, Erqian; Rafique, Ashique; Kim, Jee Hae; Harp, Joyce; Valenzuela, David M.; Yancopoulos, George D.; Murphy, Andrew J.; Gromada, Jesper 分享 收藏
ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys Gusarova, Viktoria; Alexa, Corey A.; Wang, Yan; Rafique, Ashique; Kim, Jee Hae; Buckler, David; Mintah, Ivory J.; Shihanian, Lisa M.; Cohen, Jonathan C.; Hobbs, Helen H.; Xin, Yurong; Valenzuela, David M.; Murphy, Andrew J.; Yancopoulos, George D.; Gromada, Jesper 分享 收藏
Pathogenicity of Lupus Anti-Ribosomal P Antibodies: Role of Cross-Reacting Neuronal Surface P Antigen in Glutamatergic Transmission and Plasticity in a Mouse Model Segovia-Miranda, Fabian; Serrano, Felipe; Dyrda, Agnieszka; Ampuero, Estibaliz; Retamal, Claudio; Bravo-Zehnder, Marcela; Parodi, Jorge; Zamorano, Pedro; Valenzuela, David; Massardo, Loreto; van Zundert, Brigitte; Inestrosa, Nibaldo C.; Gonzalez, Alfonso 分享 收藏
GPR17 gene disruption does not alter food intake or glucose homeostasis in mice GPR17基因破坏不会改变小鼠的食物摄入或葡萄糖稳态 Mastaitis, Jason; Min, Soo; Elvert, Ralf; Kannt, Aimo; Xin, Yurong; Ochoa, Francisca; Gale, Nicholas W.; Valenzuela, David M.; Murphy, Andrew J.; Yancopoulos, George D.; Gromada, Jesper 分享 收藏
Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes Macdonald, Lynn E.; Karow, Margaret; Stevens, Sean; Auerbach, Wojtek; Poueymirou, William T.; Yasenchak, Jason; Frendewey, David; Valenzuela, David M.; Giallourakis, Cosmas C.; Alt, Frederick W.; Yancopoulos, George D.; Murphy, Andrew J. 分享 收藏
Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice Murphy, Andrew J.; Macdonald, Lynn E.; Stevens, Sean; Karow, Margaret; Dore, Anthony T.; Pobursky, Kevin; Huang, Tammy T.; Poueymirou, William T.; Esau, Lakeisha; Meola, Melissa; Mikulka, Warren; Krueger, Pamela; Fairhurst, Jeanette; Valenzuela, David M.; Papadopoulos, Nicholas; Yancopoulos, George D. 分享 收藏
EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties EphA2通过与Akt交互促进胶质瘤干细胞在体内的浸润侵袭并调控干细胞特性 Miao, H.; Gale, N. W.; Guo, H.; Qian, J.; Petty, A.; Kaspar, J.; Murphy, A. J.; Valenzuela, D. M.; Yancopoulos, G.; Hambardzumyan, D.; Lathia, J. D.; Rich, J. N.; Lee, J.; Wang, B. 分享 收藏
Multiple knockout mouse models reveal lincRNAs are required for life and brain development Sauvageau, Martin; Goff, Loyal A.; Lodato, Simona; Bonev, Boyan; Groff, Abigail F.; Gerhardinger, Chiara; Sanchez-Gomez, Diana B.; Hacisuleyman, Ezgi; Li, Eric; Spence, Matthew; Liapis, Stephen C.; Mallard, William; Morse, Michael; Swerdel, Mavis R.; D'Ecclessis, Michael F.; Moore, Jennifer C.; Lai, Venus; Gong, Guochun; Yancopoulos, George D.; Frendewey, David; Kellis, Manolis; Hart, Ronald P.; Valenzuela, David M.; Arlotta, Paola; Rinn, John L. 分享 收藏
SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease (vol 5, pg 654, 2013) Shin, Jiyung; He, Ming; Liu, Yufei; Paredes, Silvana; Villanova, Lidia; Brown, Katharine; Qiu, Xiaolei; Nabavi, Noushin; Mohrin, Mary; Wojnoonski, Kathleen; Li, Patrick; Cheng, Hwei-Ling; Murphy, Andrew J.; Valenzuela, David M.; Luo, Hanzhi; Kapahi, Pankaj; Krauss, Ronald; Mostoslavsky, Raul; Yancopoulos, George D.; Alt, Frederick W.; Chua, Katrin F.; Chen, Danica 分享 收藏
SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease Shin, Jiyung; He, Ming; Liu, Yufei; Paredes, Silvana; Villanova, Lidia; Brown, Katharine; Qiu, Xiaolei; Nabavi, Noushin; Mohrin, Mary; Wojnoonski, Kathleen; Li, Patrick; Cheng, Hwei-Ling; Murphy, Andrew J.; Valenzuela, David M.; Luo, Hanzhi; Kapahi, Pankaj; Krauss, Ronald; Mostoslavsky, Raul; Yancopoulos, George D.; Alt, Frederick W.; Chua, Katrin F.; Chen, Danica 分享 收藏
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Conditionals by inversion provide a universal method for the generation of conditional alleles Economides, Aris N.; Frendewey, David; Yang, Peter; Dominguez, Melissa G.; Dore, Anthony T.; Lobov, Ivan B.; Persaud, Trikaldarshi; Rojas, Jose; McClain, Joyce; Lengyel, Peter; Droguett, Gustavo; Chernomorsky, Rostislav; Stevens, Sean; Auerbach, Wojtek; DeChiara, Thomas M.; Pouyemirou, William; Cruz, Joseph M., Jr.; Feeley, Kieran; Mellis, Ian A.; Yasenchack, Jason; Hatsell, Sarah J.; Xie, LiQin; Latres, Esther; Huang, Lily; Zhang, Yuhong; Pefanis, Evangelos; Skokos, Dimitris; Deckelbaum, Ron A.; Croll, Susan D.; Davis, Samuel; Valenzuela, David M.; Gale, Nicholas W.; Murphy, Andrew J.; Yancopoulos, George D. 分享 收藏
Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke Bouleti, Claire; Mathivet, Thomas; Coqueran, Berard; Serfaty, Jean-Michel; Lesage, Mathieu; Berland, Elodie; Ardidie-Robouant, Corinne; Kauffenstein, Gilles; Henrion, Daniel; Lapergue, Bertrand; Mazighi, Mikael; Duyckaerts, Charles; Thurston, Gavin; Valenzuela, David M.; Murphy, Andrew J.; Yancopoulos, George D.; Monnot, Catherine; Margaill, Isabelle; Germain, Stephane 分享 收藏
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