未登录 Paediatric Strategy Forum for medicinal product development of epigenetic modifiers for children ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration Pearson, Andrew D. J.; Stegmaier, Kimberly; Bourdeaut, Franck; Reaman, Gregory; Heenen, Delphine; Meyers, Michael L.; Armstrong, Scott A.; Brown, Patrick; De Carvalho, Daniel; Jabado, Nada; Marshall, Lynley; Rivera, Miguel; Smith, Malcolm; Adamson, Peter C.; Barone, Amy; Baumann, Christian; Blackman, Samuel; Buenger, Vickie; Donoghue, Martha; Duncan, Aundrietta D.; Fox, Elizabeth; Gadbaw, Brian; Hattersley, Maureen; Ho, Peter; Jacobs, Ira; Kelly, Michael J.; Kieran, Mark; Lesa, Giovanni; Ligas, Franca; Ludwinski, Donna; McDonough, Joe; Nikolova, Zariana; Norga, Koen; Senderowicz, Adrian; Taube, Tilmann; Weiner, Susan; Karres, Dominik; Vassal, Gilles 分享 收藏
Phase Ib results of ProSTAR: CPI-1205, EZH2 inhibitor, combined with enzalutamide (E) or abiraterone/prednisone (A/P) in patients with metastatic castration-resistant prostate cancer (mCRPC) Taplin, Mary-Ellen; Hussain, Arif; Shah, Satish; Shore, Neal D.; Edenfield, William Jeffery; Sartor, Oliver A.; Nordquist, Luke T.; Agrawal, Manish; Clark, William; Wise, David R.; Oh, William K.; Fleming, Mark T.; Butrynski, James E.; Chatta, Gurkamal S.; Bupathi, Manojkumar; Lebedinsky, Claudia; Senderowicz, Adrian; Li, Jian; Colak, Gozde; Nash, David; Trojer, Patrick; Bradley, William D.; Piel, Jessica; Antonarakis, Emmanuel S. 分享 收藏
A randomized phase II trial of CRLX101 in combination with bevacizumab versus standard of care in patients with advanced renal cell carcinoma CRLX101联合贝伐单抗与标准治疗晚期肾细胞癌患者的随机II期试验 Voss, M. H.; Hussain, A.; Vogelzang, N.; Lee, J. L.; Keam, B.; Rha, S. Y.; Vaishampayan, U.; Harris, W. B.; Richey, S.; Randall, J. M.; Shaffer, D.; Cohn, A.; Crowell, T.; Li, J.; Senderowicz, A.; Stone, E.; Figlin, R.; Motzer, R. J.; Haas, N. B.; Hutson, T. 分享 收藏
Phase 1b/2 Study of Neoadjuvant Chemoradiation Therapy With CRLX101 and Capecitabine for Locally Advanced Rectal Cancer Moon, D. H.; Mcree, A. J.; Blackstock, A. W.; O'Neil, B. H.; Moore, D. T.; Calvo, B. F.; Lee, M. S.; Murphy, C.; Caliri, K.; Tynan, M. T.; Senderowicz, A. M.; Tepper, J. E.; Sanoff, H. K.; Wang, A. Z. 分享 收藏
Significant improvements in therapeutic index for conjugated payloads using a nanoparticle-drug conjugate (NDC) platform to provide sustained drug release and potentially improved anticancer effects Metcalf, Chester, III; Van der Poll, Derek; Zhao, Liang; Halo, Tiffany; Lazarus, Doug; Stockmann, Adam; Peters, Christian; Brown, Donna; Case, Roy; Rohde, Ellen; Jayaraman, Lata; Wang, Hongwei; Crowell, Tiffany; Senderowicz, Adrian; Eliasof, Cott 分享 收藏
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Efficacy of the nanoparticle-drug conjugate CRLX101 in combination with bevacizumab in metastatic renal cell carcinoma: results of an investigator-initiated phase I-IIa clinical trial Keefe, S. M.; Hoffman-Censits, J.; Cohen, R. B.; Mamtani, R.; Heitjan, D.; Eliasof, S.; Nixon, A.; Turnbull, B.; Garmey, E. G.; Gunnarsson, O.; Waliki, M.; Ciconte, J.; Jayaraman, L.; Senderowicz, A.; Tellez, A. B.; Hennessy, M.; Piscitelli, A.; Vaughn, D.; Smith, A.; Haas, N. B. 分享 收藏
Pharmacokinetics (PK) of CRLX301 a novel nanoparticle-drug conjugate (NDC) containing the payload docetaxel, in patients with refractory solid tumors Zamboni, William C.; Markman, Ben; De Souza, Paul; Dees, E. Claire; Gangadhar, Tara; Eliasof, Scott; Murphy, Curran; Senderowicz, Adrian; Wang, Hongwei 分享 收藏
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Enhanced Skin Carcinogenesis and Lack of Thymus Hyperplasia in Transgenic Mice Expressing Human Cyclin D1b (CCND1b) Rojas, Paola; Benavides, Fernando; Blando, Jorge; Perez, Carlos; Cardenas, Kim; Richie, Ellen; Knudsen, Erik S.; Johnson, David G.; Senderowicz, Adrian M.; Rodriguez-Puebla, Marcelo L.; Conti, Claudio J. 分享 收藏
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Effects of α1-acid glycoprotein on the clinical pharmacokinetics of 7-hydroxystaurosporine Sparreboom, A; Chen, HC; Acharya, MR; Senderowicz, AM; Messmann, RA; Kuwabara, T; Venzon, DJ; Murgo, AJ; Headlee, D; Sausville, EA; Figg, WD 分享 收藏
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