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Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes MacDonald, Douglas A.; Martin, Joel; Muthusamy, Kathir K.; Luo, Jiann-Kae; Pyles, Erica; Rafique, Ashique; Huang, Tammy; Potocky, Terra; Liu, Yang; Cao, Jingtai; Bono, Francoise; Delesque, Nathalie; Savi, Pierre; Francis, John; Amirkhosravi, Ali; Meyer, Todd; Romano, Carmelo; Glinka, Meredith; Yancopoulos, George D.; Stahl, Neil; Wiegand, Stanley J.; Papadopoulos, Nicholas 分享 收藏
A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition Wei, Kevin; Piecewicz, Stephanie M.; McGinnis, Lisa M.; Taniguchi, Cullen M.; Wiegand, Stanley J.; Anderson, Keith; Chan, Carol W-M; Mulligan, Kimberly X.; Kuo, David; Yuan, Jenny; Vallon, Mario; Morton, Lori C.; Lefai, Etienne; Simon, M. Celeste; Maher, Jacquelyn J.; Mithieux, Gilles; Rajas, Fabienne; Annes, Justin P.; McGuinness, Owen P.; Thurston, Gavin; Giaccia, Amato J.; Kuo, Calvin J. 分享 收藏
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Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab 血管内皮生长因子Trap、雷珠单抗和贝伐单抗对血管内皮生长因子 (VEGF) 及相关配体的结合与中和作用 Papadopoulos, Nicholas; Martin, Joel; Ruan, Qin; Rafique, Ashique; Rosconi, Michael P.; Shi, Ergang; Pyles, Erica A.; Yancopoulos, George D.; Stahl, Neil; Wiegand, Stanley J. 分享 收藏
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A Subretinal Matrigel Rat Choroidal Neovascularization (CNV) Model and Inhibition of CNV and Associated Inflammation and Fibrosis by VEGF Trap Cao, Jingtai; Zhao, Lian; Li, Yiwen; Liu, Yang; Xiao, Weihong; Song, Ying; Luo, Lingyu; Huang, Deqiang; Yancopoulos, George D.; Wiegand, Stanley J.; Wen, Rong 分享 收藏
Cutting Edge: Lymphatic Vessels, Not Blood Vessels, Primarily Mediate Immune Rejections After Transplantation Dietrich, Tina; Bock, Felix; Yuen, Don; Hos, Deniz; Bachmann, Bjoern O.; Zahn, Grit; Wiegand, Stanley; Chen, Lu; Cursiefen, Claus 分享 收藏
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VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade Rudge, John S.; Holash, Jocelyn; Hylton, Donna; Russell, Michelle; Jiang, Shelly; Leidich, Raymond; Papadopoulos, Nicholas; Pyles, Erica A.; Torri, Al; Wiegand, Stanley J.; Thurston, Gavin; Stahl, Neil; Yancopoulos, George D. 分享 收藏
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Mice genetically deficient in neuromedin U receptor 2, but not neuromedin U receptor 1, have impaired nociceptive responses Torres, Richard; Croll, Susan D.; Vercollone, Jeffrey; Reinhardt, Joel; Griffiths, Jennifer; Zabski, Stephanie; Anderson, Keith D.; Adams, Niels C.; Gowen, Lori; Sleernan, Mark W.; Valenzuela, David M.; Wiegand, Stanley J.; Yancopoulos, George D.; Murphy, Andrew J. 分享 收藏
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Angiopoietin 1 causes vessel enlargement, without anglogenic sprouting, during a critical developmental period Thurston, G; Wang, Q; Baffert, F; Rudge, J; Papadopoulos, N; Jean-Guillaume, D; Wiegand, S; Yancopoulos, GD; McDonald, DM 分享 收藏
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity (vol 11, pg 199, 2005) Sleeman, MW; Wortley, KE; Lai, KMV; Gowen, LC; Kintner, J; Kline, WO; Garcia, K; Stitt, TN; Yancopoulos, GD; Wiegand, SJ; Glass, DJ 分享 收藏