未登录The NPXXY Motif Regulates β-Arrestin Recruitment by the CB1 Cannabinoid Receptor
Leo, Luciana M.; Al-Zoubi, Rufaida; Hurst, Dow P.; Stephan, Anna P.; Zhao, Pingwei; Tilley, Douglas G.; Miess, Elke; Schulz, Stefan; Abood, Mary E.; Reggio, Patricia H.
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收藏Design, synthesis, and evaluation of substituted alkylindoles that activate G protein-coupled receptors distinct from the cannabinoid CB1 and CB2 receptors
Kline, Toni; Xu, Cong; Kreitzer, Faith R.; Hurst, Dow P.; Eldeeb, Khalil M.; Wager-Miller, Jim; Olivas, Kathleen; Hepburn, Seon A.; Huffman, John W.; Mackie, Ken; Howlett, Allyn C.; Reggio, Patricia; Stella, Nephi
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收藏Thienopyrimidine Derivatives as GPR55 Receptor Antagonists: Insight into Structure-Activity Relationship
Figuerola-Asencio, Laura; Morales, Paula; Zhao, Pingwei; Hurst, Dow P.; Sayed, Sommayah S.; Colon, Katsuya L.; Gomez-Canas, Maria; Fernandez-Ruiz, Javier; Croatt, Mitchell P.; Reggio, Patricia H.; Abood, Mary E.; Jagerovic, Nadine
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收藏Discovery of a Biased Allosteric Modulator for Cannabinoid 1 Receptor: Preclinical Anti-Glaucoma Efficacy
Garai, Sumanta; Leo, Luciana M.; Szczesniak, Anna-Maria; Hurst, Dow P.; Schaffer, Peter C.; Zagzoog, Ayat; Black, Tallan; Deschamps, Jeffrey R.; Miess, Elke; Schulz, Stefan; Janero, David R.; Straiker, Alex; Pertwee, Roger G.; Abood, Mary E.; Kelly, Melanie E. M.; Reggio, Patricia H.; Laprairie, Robert B.; Thakur, Ganesh A.
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收藏Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators
Garai, Sumanta; Kulkarni, Pushkar M.; Schaffer, Peter C.; Leo, Luciana M.; Brandt, Asher L.; Zagzoog, Ayat; Black, Tallan; Lin, Xiaoyan; Hurst, Dow P.; Janero, David R.; Abood, Mary E.; Zimmowitch, Anaelle; Straiker, Alex; Pertwee, Roger G.; Kelly, Melanie; Szczesniak, Anna-Maria; Denovan-Wright, Eileen M.; Mackie, Ken; Hohmann, Andrea G.; Reggio, Patricia H.; Laprairie, Robert B.; Thakur, Ganesh A.
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收藏Accelerating Membrane Simulations with Hydrogen Mass Repartitioning
Balusek, Curtis; Hwang, Hyea; Lau, Chun Hon; Lundquist, Karl; Hazel, Anthony; Pavlova, Anna; Lynch, Diane L.; Reggio, Patricia H.; Wang, Yi; Gumbart, James C.
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收藏On the Validity of Hydrogen Mass Repartitioning for CHARMM36 Membrane Systems in NAMD
Gumbart, James C.; Balusek, Curtis; Hwang, Hyea; Lau, Chun Hon; Lundquist, Karl; Hazel, Anthony; Pavlova, Anna; Lynch, Diane; Reggio, Patricia; Wang, Yi
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收藏Cannabinoid Receptor CB2 Oligomerization in a Lipid Matrix
Yeliseev, Alexei; Nickels, Jonathan D.; Hines, Kirk G.; Zoubak, Lioudmila; Teague, Walter E., Jr.; Lynch, Diane L.; Hurst, Dow P.; Weiss, Kevin L.; Katsaras, John; Reggio, Patricia H.; Gawrisch, Klaus
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收藏(R)-N-(1-Methyl-2-hydroxyethyl)-13-(S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes
Liu, Yingpeng; Ji, Lipin; Eno, Marsha; Kudalkar, Shalley; Li, Ai-Ling; Schimpgen, Marion; Benchama, Othman; Morales, Paula; Xu, Shu; Hurst, Dow; Wu, Simiao; Mohammad, Khadijah A.; Wood, JodiAnne T.; Zvonok, Nikolai; Papahatjis, Demetris P.; Zhou, Han; Honrao, Chandrashekhar; Mackie, Ken; Reggio, Patricia; Hohmann, Andrea G.; Marnett, Lawrence J.; Makriyannis, Alexandros; Nikas, Spyros P.
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收藏Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone-Based Cannabinoid Receptor Type2 Ligands
Ragusa, Giulio; Bencivenni, Serena; Morales, Paula; Callaway, Tyra; Hurst, Dow P.; Asproni, Battistina; Merighi, Stefania; Loriga, Giovanni; Pinna, Gerard A.; Reggio, Patricia H.; Gessi, Stefania; Murineddu, Gabriele
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