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Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness Hirschhorn, Daniel; Warner, Allison Betof; Maniyar, Rachana; Chow, Andrew; Mangarin, Levi Mb; Cohen, Adam D.; Hamadene, Linda; Rizzuto, Gabrielle A.; Budhu, Sadna; Suek, Nathan; Liu, Cailian; Houghton, Alan N.; Merghoub, Taha; Wolchok, Jedd D. 分享 收藏
Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment Budhu, Sadna; Schaer, David A.; Li, Yongbiao; Toledo-Crow, Ricardo; Panageas, Katherine; Yang, Xia; Zhong, Hong; Houghton, Alan N.; Silverstein, Samuel C.; Merghoub, Taha; Wolchok, Jedd D. 分享 收藏
Therapeutic efficacy of antitumor monoclonal antibodies combined with chemotherapy depends on innate immunity and NK1.1-innate lymphoid cells. Moskalenko, Marina; Pan, Michael; Hashimoto, Daigo; Mortha, Arthur; Bernardo, Sebastian G.; Leboeuf, Marylene; Houghton, Alan; Wolchok, Jedd; Burakoff, Steven; Merad, Miriam; Saenger, Yvonne M. 分享 收藏
Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype Hirschhorn-Cymerman, Daniel; Budhu, Sadna; Kitano, Shigehisa; Liu, Cailian; Zhao, Feng; Zhong, Hong; Lesokhin, Alexander M.; Avogadri-Connors, Francesca; Yuan, Jianda; Li, Yanyun; Houghton, Alan N.; Merghoub, Taha; Wolchok, Jedd D. 分享 收藏
Monocytic CCR2+ Myeloid-Derived Suppressor Cells Promote Immune Escape by Limiting Activated CD8 T-cell Infiltration into the Tumor Microenvironment 单核细胞CCR2髓源性抑制细胞通过限制活化的CD8 T细胞浸润到肿瘤微环境中促进免疫逃逸 Lesokhin, Alexander M.; Hohl, Tobias M.; Kitano, Shigehisa; Cortez, Czrina; Hirschhorn-Cymerman, Daniel; Avogadri, Francesca; Rizzuto, Gabrielle A.; Lazarus, John J.; Pamer, Eric G.; Houghton, Alan N.; Merghoub, Taha; Wolchok, Jedd D. 分享 收藏
Myxoma Virus Induces Type I Interferon Production in Murine Plasmacytoid Dendritic Cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-Dependent Pathway (vol 85, pg 10814, 2011) Dai, Peihong; Cao, Hua; Merghoub, Taha; Avogadri, Francesca; Wang, Weiyi; Parikh, Tanvi; Fang, Chee-Mun; Pitha, Paula M.; Fitzgerald, Katherine A.; Rahman, Masmudur M.; McFadden, Grant; Hu, Xiaoyu; Houghton, Alan N.; Shuman, Stewart; Deng, Liang 分享 收藏
Myxoma Virus Induces Type I Interferon Production in Murine Plasmacytoid Dendritic Cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-Dependent Pathway Dai, Peihong; Cao, Hua; Merghoub, Taha; Avogadri, Francesca; Wang, Weiyi; Parikh, Tanvi; Fang, Chee-Mun; Pitha, Paula M.; Fitzgerald, Katherine A.; Rahman, Masmudur M.; McFadden, Grant; Hu, Xiaoyu; Houghton, Alan N.; Shuman, Stewart; Deng, Liang 分享 收藏
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Peptide-Loaded Langerhans Cells, Despite Increased IL15 Secretion and T-Cell Activation In Vitro, Elicit Antitumor T-Cell Responses Comparable to Peptide-Loaded Monocyte-Derived Dendritic Cells In Vivo Romano, Emanuela; Rossi, Marco; Ratzinger, Gudrun; de Cos, Maria-Angeles; Chung, David J.; Panageas, Katherine S.; Wolchock, Jedd D.; Houghton, Alan N.; Chapman, Paul B.; Heller, Glenn; Yuan, Jianda; Young, James W. 分享 收藏
Immunologic Response to Xenogeneic gp100 DNA in Melanoma Patients: Comparison of Particle-Mediated Epidermal Delivery with Intramuscular Injection Ginsberg, Brian A.; Gallardo, Humilidad F.; Rasalan, Teresa S.; Adamow, Matthew; Mu, Zhenyu; Tandon, Sapna; Bewkes, Barrett B.; Roman, Ruth-Ann; Chapman, Paul B.; Schwartz, Gary K.; Carvajal, Richard D.; Panageas, Katherine S.; Terzulli, Stephanie L.; Houghton, Alan N.; Yuan, Jianda D.; Wolchok, Jedd D. 分享 收藏
Genomic complexity and BRAF/MEK-dependence in V600E BRAF mutant melanoma Xing, Feng; Persaud, Yogindra; Pratilas, Christine; Janakiraman, Manickam; She, Qing-Bai; Liu, Cailian; Dolgalev, Igor; Heguy, Adriana; Wolchok, Jedd; Cobrinik, David; Houghton, Alan; Taylor, Barry; Rosen, Neal; Solit, David 分享 收藏
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Immune Rejection of Mouse Tumors Expressing Mutated Self Duan, Fei; Lin, Yun; Liu, Cailian; Engelhorn, Manuel E.; Cohen, Adam D.; Curran, Michael; Sakaguchi, Shimon; Merghoub, Taha; Terzulli, Stephanie; Wolchok, Jedd D.; Houghton, Alan N. 分享 收藏
Self-antigen-specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response Rizzuto, Gabrielle A.; Merghoub, Taha; Hirschhorn-Cymerman, Daniel; Liu, Cailian; Lesokhin, Alexander M.; Sahawneh, Diana; Zhong, Hong; Panageas, Katherine S.; Perales, Miguel-Angel; Altan-Bonnet, Gregoire; Wolchok, Jedd D.; Houghton, Alan N. 分享 收藏
Optimization and validation of a robust human T-cell culture method for monitoring phenotypic and polyfunctional antigen-specific CD4 and CD8 T-cell responses 用于监测表型和多功能抗原特异性CD4和CD8 T细胞反应的稳健人类T细胞培养方法的优化和验证 Lin, Yun; Gallardo, Humilidad F.; Ku, Geoffrey Y.; Li, Hao; Manukian, Gregor; Rasalan, Teresa S.; Xu, Yinyan; Terzulli, Stephanie L.; Old, Lloyd J.; Allison, James P.; Houghton, Alan N.; Wolchok, Jedd D.; Yuan, Jianda 分享 收藏
Phase I/II Study of GM-CSF DNA as an Adjuvant for a Multipeptide Cancer Vaccine in Patients With Advanced Melanoma Perales, Miguel-Angel; Yuan, Jianda; Powel, Sarah; Gallardo, Humilidad F.; Rasalan, Teresa S.; Gonzalez, Christina; Manukian, Gregor; Wang, Jian; Zhang, Yan; Chapman, Paul B.; Krown, Susan E.; Livingston, Philip O.; Ejadi, Samuel; Panageas, Katherine S.; Engelhorn, Manuel E.; Terzulli, Stephanie L.; Houghton, Alan N.; Wolchok, Jedd D. 分享 收藏
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Vaccinia Virus Subverts a Mitochondrial Antiviral Signaling Protein-Dependent Innate Immune Response in Keratinocytes through Its Double-Stranded RNA Binding Protein, E3 Deng, Liang; Dai, Peihong; Parikh, Tanvi; Cao, Hua; Bhoj, Vijay; Sun, Qinmiao; Chen, Zhijian; Merghoub, Taha; Houghton, Alan; Shuman, Stewart 分享 收藏
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