Paul P. Tak - Publications, H-index & Citations

Paul P. Tak

university zurich hospital

120H指数

833论文数

6.1W被引数

收录论文 210

发表时间

A first-in-class multimodal immunotherapy for induction of tertiary lymphoid structures as a novel therapeutic strategy for solid tumors

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Diers, Anne R.; Guo, Qiuchen; Christie, John D.; Krisky, David; Gaspal, Fabrina M.; Richardson, Erin; Smith, Charlotte G.; Withers, David R.; Croft, Adam P.; Tak, Paul P.; Barone, Francesca

Uncovering transcriptomic landscape alterations of CAN-2409 in in vitro and in vivo glioma models

FRONTIERS IN MEDICINE

IF3

2023-05-09

OAAI

Koch, Marilin S.; Zdioruk, Mykola; Nowicki, Michal O.; Hoetker, Michael S.; Herbert, Zachary T.; Barone, Francesca; Tak, Paul P.; Chiocca, E. Antonio; Tabatabai, Ghazaleh; Lawler, Sean E.

FIRST EFFICACY AND MULTI-OMIC ANALYSIS DATA FROM PHASE 1 CLINICAL TRIAL OF ONCOLYTIC VIRAL IMMUNOTHERAPY WITH CAN-2409+VALACYCLOVIR IN COMBINATION WITH NIVOLUMAB AND STANDARD OF CARE IN NEWLY DIAGNOSED HIGH-GRADE GLIOMA

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2022-12-08

OAAI

Wen, Patrick; Duault, Caroline; Gonzalez-Kozlova, Edgar; Brennan, Kevin; Holmes, Tyson; Kim-Schulze, Seunghee; Nie, Kai; Argueta, Kimberly; Fehr, Jacques; Pichavant, Mina; Del Valle, Diane; Gentles, Andrew; Gnjatic, Sacha; Maecker, Holden; Ye, Xiaobu; Reardon, David; Bi, Wenya Linda; Peruzzi, Pierpaolo; Patel, Nirav; Strowd, Roy; Tatter, Stephen; Lee, Ian; Walbert, Tobias; Snyder, James; Brem, Steven; Desai, Arati; Bagley, Stephen; Amankulor, Nduka; Lieberman, Frank; Mantica, Megan; Lopez, Lenika; Bell, Susan; Manzanera, Andrea; Lawler, Sean; Jin, Lixian; Danda, Neeraja; Desideri, Serena; Nabors, L. Burt; Grossman, Stuart; Chiocca, E.; Tak, Paul; Barone, Francesca

A randomized, phase II study of sequential belimumab and rituximab in primary Sjogren's syndrome 序贯贝利木单抗和利妥昔单抗治疗原发性干燥综合征的随机II期研究

JCI INSIGHT

IF6.1

2022-12-08

OAAI

Mariette, Xavier; Barone, Francesca; Baldini, Chiara; Bootsma, Hendrika; Clark, Kenneth L.; De Vita, Salvatore; Gardner, David H.; Henderson, Robert B.; Herdman, Michael; Lerang, Karoline; Mistry, Prafull; Punwaney, Raj; Seror, Raphaele; Stone, John; Daele, Paul La van; van Maurik, Andre; Wisniacki, Nicolas; Roth, David A.; Tak, Paul Peter

Synovial gene signatures associated with the development of rheumatoid arthritis in at risk individuals: A prospective study

JOURNAL OF AUTOIMMUNITY

IF7

2022-12-01

OAAI

de Jong, Tineke A.; de Hair, Maria J. H.; van de Sande, Marleen G. H.; Semmelink, Johanna F.; Choi, Ivy Y.; Gerlag, Danielle M.; Tak, Paul P.; van Baarsen, Lisa G. M.

DYNAMIC ANALYSES OF TUMOR MICROENVIRONMENT MODULATION BY CAN-2409 TREATMENT USING KAEDE PHOTOCONVERTIBLE TRANSGENIC MICE

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2022-11-07

OAAI

Withers, David; Diers, Anne; Li, Zhi; Idris, Suaad; Willis, Claire; Tak, Paul Peter; Barone, Francesca

Perturbing DDR signaling enhances cytotoxic effects of local oncolytic virotherapy and modulates the immune environment in glioma

MOLECULAR THERAPY-ONCOLYTICS

IF0

2022-09-01

OAAI

Koch, Marilin S.; Zdioruk, Mykola; Nowicki, Michal O.; Griffith, Alec M.; Aguilar-Cordova, Estuardo; Aguilar, Laura K.; Guzik, Brian W.; Barone, Francesca; Tak, Paul Peter; Schregel, Katharina; Hoetker, Michael S.; Lederer, James A.; Chiocca, E. Antonio; Tabatabai, Ghazaleh; Lawler, Sean E.

Systemic high-dose dexamethasone treatment may modulate the efficacy of intratumoral viral oncolytic immunotherapy in glioblastoma models

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2022-01-11

OAAI

Koch, Marilin S.; Zdioruk, Mykola; Nowicki, Michal O.; Griffith, Alec M.; Aguilar, Estuardo; Aguilar, Laura K.; Guzik, Brian W.; Barone, Francesca; Tak, Paul P.; Tabatabai, Ghazaleh; Lederer, James A.; Chiocca, E. Antonio; Lawler, Sean

DETECTION OF VIRAL ANTIGEN AND IMMUNE ACTIVATION AFTER INTRA-TUMOR INJECTION OF CAN-3110 (ICP-34.5 EXPRESSING HSV-1 ONCOLYTIC VIRUS) IN PATIENTS WITH RECURRENT HIGH-GRADE GLIOMA

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2021-11-10

OAAI

Barone, Francesca; Lawler, Sean; Aguilar, Laura; Dwyer, Jessica; Guzik, Brian; Soloman, Isaac; Nakashima, Hiroshi; Triggs, Daniel; Zhang, Abigail Tianai; Zeng, Yu; Woods, Jared; Grant, James; Reardon, David; Wen, Patrick; Lee, Eudocia Quant; Ligon, Keith; Pisano, William; Rodig, Scott; Suva, Mario; Wucherpfennig, Kai; Marx, Sascha; Gritsch, Simon; Mathewson, Nathan; Severgnini, Mariano; Giobbie-Hurder, Anita; Krisky, David; Aguilar-Cordova, Estuardo; Tak, Paul; Chiocca, E. Antonio

Immune-mediated inflammation across disease boundaries: breaking down research silos

NATURE IMMUNOLOGY

IF27.6

2021-10-21

PREAI

Buckley, Christopher D.; Chernajovsky, Lorna; Chernajovsky, Yuti; Modis, Louise K.; O'Neill, Luke A.; Brown, Doug; Connor, Rachel; Coutts, David; Waterman, Elizabeth A.; Tak, Paul P.

A randomised, placebo-controlled study of RIPK1 inhibitor GSK2982772 in patients with active ulcerative colitis

BMJ OPEN GASTROENTEROLOGY

IF2.9

2021-08-13

OAAI

Weisel, Kathy; Scott, Nicola; Berger, Scott; Wang, Susanne; Brown, Kurt; Powell, Marcy; Broer, Matthijs; Watts, Clarissa; Tompson, Debra J.; Burriss, Susan W.; Hawkins, Simon; Abbott-Banner, Kathy; Tak, Paul Peter

Novel Insights Into Rheumatoid Arthritis Through Characterization of Concordant Changes in DNA Methylation and Gene Expression in Synovial Biopsies of Patients With Differing Numbers of Swollen Joints

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-04-22

OAAI

Li Yim, Andrew Y. F.; Ferrero, Enrico; Maratou, Klio; Lewis, Huw D.; Royal, George; Tough, David F.; Larminie, Chris; Mannens, Marcel M. A. M.; Henneman, Peter; de Jonge, Wouter J.; van de Sande, Marleen G. H.; Gerlag, Danielle M.; Prinjha, Rab K.; Tak, Paul P.

Efficacy, patient-reported outcomes, and safety of the anti-granulocyte macrophage colony-stimulating factor antibody otilimab (GSK3196165) in patients with rheumatoid arthritis: a randomised, phase 2b, dose-ranging study

LANCET RHEUMATOLOGY

IF16.4

2020-11-01

OAAI

Buckley, Christopher D.; Simon-Campos, Jesus A.; Zhdan, Vyacheslav; Becker, Brandon; Davy, Katherine; Fisheleva, Elena; Gupta, Anubha; Hawkes, Carol; Inman, David; Layton, Mark; Mitchell, Nina; Patel, Jatin; Saurigny, Didier; Williamson, Russell; Tak, Paul P.

MRI of the joint and evaluation of the granulocyte-macrophage colony-stimulating factor-CCL17 axis in patients with rheumatoid arthritis receiving otilimab: a phase 2a randomised mechanistic study

LANCET RHEUMATOLOGY

IF16.4

2020-11-01

OAAI

Genovese, Mark C.; Berkowitz, Mario; Conaghan, Philip G.; Peterfy, Charles; Davy, Katherine; Fisheleva, Elena; Gupta, Anubha; Inman, David; Janiczek, Robert; Layton, Mark; Mitchell, Nina; Patel, Jatin; Roberts, Alexandra; Saurigny, Didier; Smith, Julia E.; Williamson, Russell; Tak, Paul P.

Response to Inhibition of Receptor-Interacting Protein Kinase 1 (RIPK1) in Active Plaque Psoriasis: A Randomized Placebo-Controlled Study

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2020-07-07

OAAI

Weisel, Kathleen; Berger, Scott; Papp, Kim; Maari, Catherine; Krueger, James G.; Scott, Nicola; Tompson, Debra; Wang, Susanne; Simeoni, Monica; Bertin, John; Peter Tak, Paul

Adherence to Treat-to-target Management in Rheumatoid Arthritis and Associated Factors: Data from the International RA BIODAM Cohort

JOURNAL OF RHEUMATOLOGY

IF3.4

2019-09-15

OAAI

Sepriano, Alexandre; Ramiro, Sofia; FitzGerald, Oliver; Ostergaard, Mikkel; Homik, Joanne; van der Heijde, Desiree; Elkayam, Ori; Thorne, J. Carter; Larche, Maggie J.; Ferraccioli, Gianfranco; Backhaus, Marina; Burmester, Gerd R.; Boire, Gilles; Combe, Bernard; Schaeverbeke, Thierry; Saraux, Alain; Dougados, Maxime; Rossini, Maurizio; Govoni, Marcello; Sinigaglia, Luigi; Cantagrel, Alain; Barnabe, Cheryl; Bingham, Clifton O., III; Tak, Paul P.; van Schaardenburg, Dirkjan; Hammer, Hilde Berner; Paschke, Joel; Dadashova, Rana; Hutchings, Edna; Landewe, Robert; Maksymowych, Walter P.

Molecular Characterization of Human Lymph Node Stromal Cells During the Earliest Phases of Rheumatoid Arthritis

FRONTIERS IN IMMUNOLOGY

IF5.9

2019-08-20

OAAI

Karouzakis, Emmanuel; Hahnlein, Janine; Grasso, Cristoforo; Semmelink, Johanna F.; Tak, Paul P.; Gerlag, Danielle M.; Gay, Steffen; Ospelt, Caroline; van Baarsen, Lisa G. M.

Myeloid Dendritic Cells Are Enriched in Lymph Node Tissue of Early Rheumatoid Arthritis Patients but not in At Risk Individuals

CELLS

IF5.2

2019-07-20

OAAI

Ramwadhdoebe, T. H.; Ramos, M., I; Maijer, K., I; van Lienden, K. P.; Maas, M.; Gerlag, D. M.; Tak, P. P.; Lebre, M. C.; van Baarsen, L. G. M.

Therapeutic options for targeting inflammatory osteoarthritis pain

NATURE REVIEWS RHEUMATOLOGY

IF32.7

2019-05-08

275

OAAI

Conaghan, Philip G.; Cook, Andrew D.; Hamilton, John A.; Tak, Paul P.

Physician's Global Assessment in Psoriatic Arthritis: A Multicenter GRAPPA Study

JOURNAL OF RHEUMATOLOGY

IF3.4

2018-06-15

OAAI

Cauli, Alberto; Gladman, Dafna D.; Mathieu, Alessandro; Olivieri, Ignazio; Porru, Giovanni; Tak, Paul P.; Sardu, Claudia; Scarpa, Raffaele; Marchesoni, Antonio; Taylor, William J.; Salvarani, Carlo; Kalden, Joachim; Lubrano, Ennio; Carneiro, Sueli; Piga, Matteo; Floris, Alberto; Desiati, Francesca; Flynn, John A.; D'Angelo, Salvatore; van Kuijk, Arno W. R.; Catanoso, Maria Grazia; Caso, Francesco; Contu, Paolo; Ujfalussy, Ilona; Helliwell, Philip S.; Mease, Philip J.

研究方向