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Oliver Lenz

Johnson & Johnson

39H指数
211论文数
6.4K被引数
收录论文 72
发表时间
Population Pharmacokinetics of siRNA JNJ-73763989 in Healthy Participants and Patients With Chronic Hepatitis B健康受试者和慢性乙型肝炎患者中siRNA JNJ-73763989的群体药代动力学
err2025-05-15
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PREAI
errTetsuro Ogawa; Nele Goeyvaerts; Thomas N. Kakuda; Joris J. Vandenbossche; Juan José Pérez-Ruixo; Oliver Ackaert; Emmanuel Njumbe Ediage; Michael Biermer; Oliver Lenz; Hong Su; Huybrecht T'jollyn
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Serum levels of hepatitis B core antibodies and hepatitis B core-related antigen at the time of nucleos(t)ide analog cessation and risk of severe flares in patients with chronic hepatitis B
err2025-03-01
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PREAI
errvan Boemmel, Florian; Verbinnen, Thierry; Agarwal, Kosh; Vanwolleghem, Thomas; Lampertico, Pietro; Buti, Maria; Janczewska, Ewa; Bourliere, Marc; Jezorwski, John; Donohue, Kathleen; Kim, Gloria; Kakuda, Thomas N.; De Meyer, Sandra; Bakala, Adam; Biermer, Michael; Lenz, Oliver
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Prevalence of Hepatitis D Virus Antibody Positivity in Chinese Patients with Chronic Hepatitis B Virus Infection中国慢性乙型肝炎病毒感染患者中D型肝炎病毒抗体阳性的患病率
err2025-02-24
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errLiang, Xieer; Chen, Qiaoqiao; Tang, Hong; Guan, Yujuan; Liang, Minfeng; Hu, Peng; Xie, Wen; Rao, Huiying; Niu, Junqi; Chen, Liang; Yan, Li; Chen, Xiaowei; Li, Xiaohe; Zhao, Yulin; Lenz, Oliver; Biermer, Michael; Hou, Jinlin
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JNJ-73763989 and bersacapavir treatment in nucleos(t)ide analogue-suppressed patients with chronic hepatitis B: REEF-2
err2024-09-01
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errAgarwal, Kosh; Buti, Maria; van Boemmel, Florian; Lampertico, Pietro; Janczewska, Ewa; Bourliere, Marc; Vanwolleghem, Thomas; Lenz, Oliver; Verbinnen, Thierry; Kakuda, Thomas N.; Mayer, Cristiana; Jezorwski, John; Muenz, Daniel; Beumont, Maria; Kalmeijer, Ronald; Biermer, Michael; Lonjon-Domanec, Isabelle
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HDV RNA assays: Performance characteristics, clinical utility, and challenges
err2023-08-28
err9
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errWedemeyer, Heiner; Leus, Mitchell; Battersby, Thomas R.; Glenn, Jeffrey; Gordien, Emmanuel; Kamili, Saleem; Kapoor, Hema; Kessler, Harald H.; Lenz, Oliver; Luetgehetmann, Marc; Mixson-Hayden, Tonya; Simon, Christian O.; Thomson, Michael; Westman, Gabriel; Miller, Veronica; Terrault, Norah; Lampertico, Pietro
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Chronic Hepatitis B Finite Treatment: Similar and Different Concerns With New Drug Classes慢性乙型肝炎有限治疗: 新药课程的相似和不同问题
err2023-08-26
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errPeters, Marion G.; Yuen, Man-Fung; Terrault, Norah; Fry, John; Lampertico, Pietro; Gane, Ed; Hwang, Carey; Stamm, Luisa M.; Leus, Mitchell; Maini, Mala K.; Mendez, Patricia; Lonjon-Domanec, Isabelle; Berg, Thomas; Wang, Su; Mishra, Poonam; Donaldson, Eric; Buchholz, Stephanie; Miller, Veronica; Lenz, Oliver
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Combination treatments including the small-interfering RNA JNJ-3989 induce rapid and sometimes prolonged viral responses in patients with CHB
err2022-11-01
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errYuen, Man-Fung; Locarnini, Stephen; Lim, Tien Huey; Strasser, Simone, I; Sievert, William; Cheng, Wendy; Thompson, Alex J.; Given, Bruce D.; Schluep, Thomas; Hamilton, James; Biermer, Michael; Kalmeijer, Ronald; Beumont, Maria; Lenz, Oliver; De Ridder, Filip; Cloherty, Gavin; Wong, Danny Ka-Ho; Schwabe, Christian; Jackson, Kathy; Lai, Ching Lung; Gish, Robert G.; Gane, Edward
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Safety, antiviral activity and pharmacokinetics of JNJ-64530440, a novel capsid assembly modulator, as 4 week monotherapy in treatment-naive patients with chronic hepatitis B virus infection
err2022-01-19
err9
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errGane, Ed J.; Schwabe, Christian; Berliba, Elina; Tangkijvanich, Pisit; Jucov, Alina; Ghicavii, Nelea; Verbinnen, Thierry; Lenz, Oliver; Talloen, Willem; Kakuda, Thomas N.; Westland, Chris; Patel, Megha; Yogaratnam, Jeysen Z.; Dragone, Leonard; Van Remoortere, Pieter
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JNJ-56136379, an HBV Capsid Assembly Modulator, Is Well-Tolerated and Has Antiviral Activity in a Phase 1 Study of Patients With Chronic Infection
err2020-08-01
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errZoulim, Fabien; Lenz, Oliver; Vandenbossche, Joris J.; Talloen, Willem; Verbinnen, Thierry; Moscalu, Iurie; Streinu-Cercel, Adrian; Bourgeois, Stefan; Buti, Maria; Crespo, Javier; Pascasio, Juan Manuel; Sarrazin, Christoph; Vanwolleghem, Thomas; Shukla, Umesh; Fry, John; Yogaratnam, Jeysen Z.
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Anti-HBV activity of the HBV capsid assembly modulator JNJ-56136379 across full-length genotype A-H clinical isolates and core site-directed mutants in vitro
err2020-05-17
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PREAI
errVerbinnen, Thierry; Tan, Ying; Wang, Gengyan; Dehertogh, Pascale; Vergauwen, Karen; Neefs, Jean-Marc; Jacoby, Edgar; Lenz, Oliver; Berke, Jan Martin
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Sequence analysis of baseline and on-treatment samples from HBV-infected chronic hepatitis B patients treated for 28 days with JNJ-56136379 monotherapy
err2019-04-01
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PREAI
errVerbinnen, Thierry; Hodari, Moana; Talloen, Willem; Berke, Jan Martin; Blue, David; Yogaratnam, Jeysen; Shukla, Umesh; De Meyer, Sandra; Lenz, Oliver
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Safety, antiviral activity, and pharmacokinetics of a novel hepatitis B virus capsid assembly modulator, JNJ-56136379, in Asian and non-Asian patients with chronic hepatitis B
err2019-04-01
err3
PREAI
errYogaratnam, Jeysen; Zoulim, Fabien; Vandenbossche, Joris; Lenz, Oliver; Talloen, Willem; Moscalu, Iurie; Mohamed, Rosmawati; Streinu-Cercel, Adrian; Chuang, Wan-Long; Bourgeois, Stefan; Yang, Sheng-Shun; Buti, Maria; Crespo, Javier; Chen, Yi-Cheng; Manuel Pascasio, Juan; Sarrazin, Christoph; Vanwolleghem, Thomas; Shukla, Umesh; Fry, John
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Antiviral Activity, Safety, and Pharmacokinetics of Capsid Assembly Modulator NVR 3-778 in Patients with Chronic HBV Infection
err2019-04-01
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errYuen, Man Fung; Gane, Edward J.; Kim, Dong Joon; Weilert, Frank; Chan, Henry Lik Yuen; Lalezari, Jacob; Hwang, Seong Gyu; Tuan Nguyen; Flores, Osvaldo; Hartman, George; Liaw, Sandy; Lenz, Oliver; Kakuda, Thomas N.; Talloen, Willem; Schwabe, Christian; Klumpp, Klaus; Brown, Nathaniel
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HBcrAg decline in JNJ-56136379-treated chronic hepatitis B patients: Results of a phase 1 study
err2019-04-01
err8
PREAI
errLenz, Oliver; Verbinnen, Thierry; Hodari, Moana; Talloen, Willem; Vandenbossche, Joris; Shukla, Umesh; Berby, Francoise; Scholtes, Caroline; Blue, David; Yogaratnam, Jeysen; De Meyer, Sandra; Zoulim, Fabien
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Effect of Plasma Protein Binding on the Anti-Hepatitis B Virus Activity and Pharmacokinetic Properties of NVR 3-778
err2018-11-01
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errHelsen, Nicky; Vervoort, Tom; Vandenbossche, Joris; Len, Oliver; Monshouwer, Mario; Pauwels, Frederik; Snoeys, Jan
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Safety, pharmakokinetics and antiviral activity of novel capsid assembly modulator (CAM) JNJ-56136379 (JNJ-6379) in treatmentnaive chronic hepatitis B (CHB) patients without cirrhosis
err2018-04-01
err10
PREAI
errZoulim, F.; Yogaratnam, J. Z.; Vandenbossche, J. J.; Lenz, O.; Talloen, W.; Vistuer, C.; Moscalu, I.; Streinu-Cercel, A.; Bourgeois, S.; Buti, M.; Crespo, J.; Pascasio, J. M.; Sarrazin, C.; Vanwolleghem, T.; Blatt, L.; Fry, J.
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A 3-year follow-up study after treatment with simeprevir in combination with pegylated interferon-α and ribavirin for chronic hepatitis C virus infection
err2018-01-30
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errZoulim, Fabien; Moreno, Christophe; Lee, Samuel S.; Buggisch, Peter; Horban, Andrzej; Lawitz, Eric; Corbett, Chris; Lenz, Oliver; Fevery, Bart; Verbinnen, Thierry; Shukla, Umesh; Jessner, Wolfgang
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Simeprevir with peginterferon α-2a/ribavirin for chronic hepatitis C virus genotype 1 infection in treatment-experienced patients: an open-label, rollover study
err2017-06-02
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errGane, Edward J.; DeJesus, Edwin; Janczewska, Ewa; George, Jacob; Diago, Moises; Da Silva, Mariliza Hendrique; Reesink, Henk; Nikitin, Igor; Hinrichsen, Holger; Bourgeois, Stefan; Ferenci, Peter; Shukla, Umesh; Kalmeijer, Ronald; Lenz, Oliver; Fevery, Bart; Corbett, Chris; Beumont, Maria; Jessner, Wolfgang
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In vitro virology profile of the 3 direct-acting antiviral combination of AL-335, odalasvir and simeprevir
err2017-01-01
err5
PREAI
errVijgen, L.; Fevery, B.; Jekle, A.; Shaw, K.; Tan, H.; Lenz, O.; Symons, J.; De Meyer, S.
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