Eckhard Leifke - Publications, H-index & Citations

Eckhard Leifke

University of South Alabama

19H指数

90论文数

2.2K被引数

收录论文 24

发表时间

The pharmacokinetics and safety of vonoprazan in adolescents and children with gastroesophageal reflux disease Vonoprazan在青少年和儿童胃食管反流病中的药代动力学和安全性

Journal of Pediatric Gastroenterology and Nutrition

IF2.6

2026-02-01

OAAI

Mulford, Darcy J.; Gremse, David A.; Chang, Yu-Ming; Leifke, Eckhard; Wagner, Thomas; Facius, Axel; Witt, Galen

Vonoprazan is Efficacious for Treatment of Heartburn in Non-erosive Reflux Disease: A Randomized Trial 沃诺拉赞可有效治疗非糜烂性反流病的胃灼热: 一项随机试验

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

IF12

2024-11-01

OAAI

Laine, Loren; Spechler, Stuart; Yadlapati, Rena; Schnoll-Sussman, Felice; Smith, Neila; Leifke, Eckhard; Harris, Tom; Hunt, Barbara; Fass, Ronnie; Katz, Philip

Vonoprazan Improves Nocturnal Gastroesophageal Reflux Symptoms in Non-Erosive Reflux Disease

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2024-10-01

PREAI

Antunes, Catiele; Ghosh, Gaurav; Katz, Philip; Yadlapati, Rena; Leifke, Eckhard; Harris, Thomas; Graham, Hillary; Laine, Loren

Heartburn Frequency and Symptom Improvement Rates of Treated Episodes when Switching From Daily to On-Demand Vonoprazan Treatment for Non-erosive Reflux Disease

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2024-10-01

PREAI

Fass, Ronnie; Chen, Joan W.; Heidelbaugh, Joel J.; Patel, Anish; Chokshi, Reena V.; Harris, Thomas; Graham, Hillary; Leifke, Eckhard; Armstrong, David

Mathematical model of the relationship between pH holding time and erosive esophagitis healing rates

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2024-09-19

OAAI

Howden, Colin W.; Scarpignato, Carmelo; Leifke, Eckhard; Mulford, Darcy J.; Lahu, Gezim; Facius, Axel; Yuan, Yuhong; Hunt, Richard

Randomised clinical trial: Efficacy and safety of on-demand vonoprazan versus placebo for non-erosive reflux disease

ALIMENTARY PHARMACOLOGY & THERAPEUTICS

IF6.7

2023-09-26

OAAI

Fass, Ronnie; Vaezi, Michael; Sharma, Prateek; Yadlapati, Rena; Hunt, Barbara; Harris, Tom; Smith, Neila; Leifke, Eckhard; Armstrong, David

Brief communication: global temporal trends in the efficacy of clarithromycin-based regimens for the treatment of Helicobacter pylori infection 简短通讯: 基于克拉霉素的方案治疗幽门螺杆菌感染的疗效的全球时间趋势

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY

IF3.4

2023-06-22

OAAI

Moss, Steven F.; Chey, William D.; Daniele, Patrick; Pelletier, Corey; Jacob, Rinu; Tremblay, Gabriel; Hubscher, Elizabeth; Leifke, Eckhard; Malfertheiner, Peter

A translational pharmacokinetic/pharmacodynamic approach supports optimal vonoprazan dosing for erosive oesophagitis and Helicobacter pylori infection

ALIMENTARY PHARMACOLOGY & THERAPEUTICS

IF6.7

2023-04-17

OAAI

Scarpignato, Carmelo; Howden, Colin W.; Leifke, Eckhard; Mulford, Darcy J.; Lahu, Gezim; Facius, Axel; Hunt, Richard

Tiered approach to evaluate the CYP3A victim and perpetrator drug-drug interaction potential for vonoprazan using PBPK modeling and clinical data to inform labeling

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2023-03-10

OAAI

Mulford, Darcy J.; Ramsden, Diane; Zhang, Liming; Michon, Ingrid; Leifke, Eckhard; Smith, Neila; Jones, Hannah M.; Scarpignato, Carmelo

Response to Graham

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2022-11-01

PREAI

Laine, Loren; Sharma, Prateek; Mulford, Darcy J.; Hunt, Barbara; Leifke, Eckhard; Smith, Neila; Howden, Colin W.

Rates of Antimicrobial Resistance in Helicobacter pylori Isolates From Clinical Trial Patients Across the US and Europe

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2022-09-30

OAAI

Megraud, Francis; Graham, David Y.; Howden, Colin W.; Trevino, Ernest; Weissfeld, Alice; Hunt, Barbara; Smith, Neila; Leifke, Eckhard; Chey, William D.

Pharmacodynamics and Pharmacokinetics of the Potassium-Competitive Acid Blocker Vonoprazan and the Proton Pump Inhibitor Lansoprazole in US Subjects

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2022-03-16

PREAI

Laine, Loren; Sharma, Prateek; Mulford, Darcy J.; Hunt, Barbara; Leifke, Eckhard; Smith, Neila; Howden, Colin W.

A Multiple-Ascending-Dose Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of a Novel GPR40 Agonist, TAK-875, in Subjects With Type 2 Diabetes

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2012-06-06

PREAI

Leifke, E.; Naik, H.; Wu, J.; Viswanathan, P.; DeManno, D.; Kipnes, M.; Vakilynejad, M.

TAK-875 versus placebo or glimepiride in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial

LANCET

IF88.5

2012-04-01

222

PREAI

Burant, Charles F.; Viswanathan, Prabhakar; Marcinak, John; Cao, Charlie; Vakilynejad, Majid; Xie, Benhuai; Leifke, Eckhard

Shift From Surrogate End Point to Outcome Trials: Implications for Cardiovascular Safety Assessment in Development Programs for Antidiabetic Drugs

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2011-11-23

PREAI

Marcinak, J. F.; Viswanathan, P.; Arora, V.; Roebel, L. E.; Strack, T. R.; Leifke, E.

CLINICAL ENDOCRINOLOGY

IF2.4

2008-07-07

225

PREAI

Leifke, E; Gorenoi, V; Wichers, C; von zur Mühlen, A; von Büren, E; Brabant, G

Differences in symptom scores and health outcomes in premenstrual syndrome

JOURNAL OF WOMENS HEALTH

IF1.9

2007-10-01

PREAI

Borenstein, Jeff E.; Dean, Bonnie B.; Leifke, Eckhard; Korner, Paul; Yonkers, Kimberly A.

The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY

IF4.7

2007-01-22

OAAI

Bone, Wilhelm; Walden, Charlotte M.; Fritsch, Martin; Voigtmann, Ulrike; Leifke, Eckhard; Gottwald, Ulrich; Boomkamp, Stephanie; Platt, Frances M.; van der Spoel, Aarnoud C.

Miglustat has no apparent effect on spermatogenesis in normal men

HUMAN REPRODUCTION

IF6.1

2006-10-25

OAAI

Amory, J. K.; Muller, C. H.; Page, S. T.; Leifke, E.; Pagel, E. R.; Bhandari, A.; Subramanyam, B.; Bone, W.; Radlmaier, A.; Bremner, W. J.

Sex steroids and body composition in men with cystic fibrosis

EUROPEAN JOURNAL OF ENDOCRINOLOGY

IF5.2

2003-05-01

OAAI

Leifke, E; Friemert, M; Heilmann, M; Puvogel, N; Smaczny, C; von zur Mühlen, A; Brabant, G

研究方向