未登录 GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture 超过29,000名癫痫患者的ghis荟萃分析确定了26个风险基因座和亚型特异性遗传结构 Stevelink, Remi; Campbell, Ciaran; Chen, Siwei; Abou-Khalil, Bassel; Adesoji, Oluyomi M.; Afawi, Zaid; Amadori, Elisabetta; Anderson, Alison; Anderson, Joseph; Andrade, Danielle M.; Annesi, Grazia; Auce, Pauls; Avbersek, Andreja; Bahlo, Melanie; Baker, Mark D.; Balagura, Ganna; Balestrini, Simona; Barba, Carmen; Barboza, Karen; Bartolomei, Fabrice; Bast, Thomas; Baum, Larry; Baumgartner, Tobias; Baykan, Betul; Bebek, Nerses; Becker, Albert J.; Becker, Felicitas; Bennett, Caitlin A.; Berghuis, Bianca; Berkovic, Samuel F.; Beydoun, Ahmad; Bianchini, Claudia; Bisulli, Francesca; Blatt, Ilan; Bobbili, Dheeraj R.; Borggraefe, Ingo; Bosselmann, Christian; Braatz, Vera; Bradfield, Jonathan P.; Brockmann, Knut; Brody, Lawrence C.; Buono, Russell J.; Busch, Robyn M.; Caglayan, Hande; Campbell, Ellen; Canafoglia, Laura; Canavati, Christina; Cascino, Gregory D.; Castellotti, Barbara; Catarino, Claudia B.; Cavalleri, Gianpiero L.; Cerrato, Felecia; Chassoux, Francine; Cherny, Stacey S.; Cheung, Ching-Lung; Chinthapalli, Krishna; Chou, I-Jun; Chung, Seo-Kyung; Churchhouse, Claire; Clark, Peggy O.; Cole, Andrew J.; Compston, Alastair; Coppola, Antonietta; Cosico, Mahgenn; Cossette, Patrick; Craig, John J.; Cusick, Caroline; Daly, Mark J.; Davis, Lea K.; de Haan, Gerrit-Jan; Delanty, Norman; Depondt, Chantal; Derambure, Philippe; Devinsky, Orrin; Di Vito, Lidia; Dlugos, Dennis J.; Doccini, Viola; Doherty, Colin P.; El-Naggar, Hany; Elger, Christian E.; Ellis, Colin A.; Eriksson, Johan G.; Faucon, Annika; Feng, Yen-Chen A.; Ferguson, Lisa; Ferraro, Thomas N.; Ferri, Lorenzo; Feucht, Martha; Fitzgerald, Mark; Fonferko-Shadrach, Beata; Fortunato, Francesco; Franceschetti, Silvana; Franke, Andre; French, Jacqueline A.; Freri, Elena; Gagliardi, Monica; Gambardella, Antonio; Geller, Eric B.; Giangregorio, Tania; Gjerstad, Leif; Glauser, Tracy; Goldberg, Ethan; Goldman, Alicia; Granata, Tiziana; Greenberg, David A.; Guerrini, Renzo; Gupta, Namrata; Haas, Kevin F.; Hakonarson, Hakon; Hallmann, Kerstin; Hassanin, Emadeldin; Hegde, Manu; Heinzen, Erin L.; Helbig, Ingo; Hengsbach, Christian; Heyne, Henrike O.; Hirose, Shinichi; Hirsch, Edouard; Hjalgrim, Helle; Howrigan, Daniel P.; Hucks, Donald; Hung, Po-Cheng; Iacomino, Michele; Imbach, Lukas L.; Inoue, Yushi; Ishii, Atsushi; Jamnadas-Khoda, Jennifer; Jehi, Lara; Johnson, Michael R.; Kalviainen, Reetta; Kamatani, Yoichiro; Kanaan, Moien; Kanai, Masahiro; Kantanen, Anne-Mari; Kara, Bulent; Kariuki, Symon M.; Kasperaviciute, Dalia; Trenite, Dorothee Kasteleijn-Nolst; Kato, Mitsuhiro; Kegele, Josua; Kesim, Yescommaim; Khoueiry-Zgheib, Nathalie; King, Chontelle; Kirsch, Heidi E.; Klein, Karl M.; Kluger, Gerhard; Knake, Susanne; Knowlton, Robert C.; Koeleman, Bobby P. C.; Korczyn, Amos D.; Koupparis, Andreas; Kousiappa, Ioanna; Krause, Roland; Krenn, Martin; Krestel, Heinz; Krey, Ilona; Kunz, Wolfram S.; Kurki, Mitja I.; Kurlemann, Gerhard; Kuzniecky, Ruben; Kwan, Patrick; Labate, Angelo; Lacey, Austin; Lal, Dennis; Landoulsi, Zied; Lau, Yu-Lung; Lauxmann, Stephen; Leech, Stephanie L.; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Lesca, Gaetan; Leu, Costin; Lewin, Naomi; Lewis-Smith, David; Li, Gloria H. -Y.; Li, Qingqin S.; Licchetta, Laura; Lin, Kuang-Lin; Lindhout, Dick; Linnankivi, Tarja; Lopes-Cendes, Iscia; Lowenstein, Daniel H.; Lui, Colin H. T.; Madia, Francesca; Magnusson, Sigurdur; Marson, Anthony G.; May, Patrick; McGraw, Christopher M.; Mei, Davide; Mills, James L.; Minardi, Raffaella; Mirza, Nasir; Moller, Rikke S.; Molloy, Anne M.; Montomoli, Martino; Mostacci, Barbara; Muccioli, Lorenzo; Muhle, Hiltrud; Mueller-Schlueter, Karen; Najm, Imad M.; Nasreddine, Wassim; Neale, Benjamin M.; Neubauer, Bernd; Newton, Charles R. J. C.; Noethen, Markus M.; Nothnagel, Michael; Nuernberg, Peter; O'Brien, Terence J.; Okada, Yukinori; Olafsson, Elias; Oliver, Karen L.; Ozkara, Cigdem; Palotie, Aarno; Pangilinan, Faith; Papacostas, Savvas S.; Parrini, Elena; Pato, Carlos N.; Pato, Michele T.; Pendziwiat, Manuela; Petrovski, Slave; Pickrell, William O.; Pinsky, Rebecca; Pippucci, Tommaso; Poduri, Annapurna; Pondrelli, Federica; Powell, Rob H. W.; Privitera, Michael; Rademacher, Annika; Radtke, Rodney; Ragona, Francesca; Rau, Sarah; Rees, Mark I.; Regan, Brigid M.; Reif, Philipp S.; Rhelms, Sylvain; Riva, Antonella; Rosenow, Felix; Ryvlin, Philippe; Saarela, Anni; Sadleir, Lynette G.; Sander, Josemir W.; Sander, Thomas; Scala, Marcello; Scattergood, Theresa; Schachter, Steven C.; Schankin, Christoph J.; Scheffer, Ingrid E.; Schmitz, Bettina; Schoch, Susanne; Schubert-Bast, Susanne; Schulze-Bonhage, Andreas; Scudieri, Paolo; Sham, Pak; Sheidley, Beth R.; Shih, Jerry J.; Sills, Graeme J.; Sisodiya, Sanjay M.; Smith, Michael C.; Smith, Philip E.; Sonsma, Anja C. M.; Speed, Doug; Sperling, Michael R.; Stefansson, Hreinn; Stefansson, Kari; Steinhoff, Bernhard J.; Stephani, Ulrich; Stewart, William C.; Stipa, Carlotta; Striano, Pasquale; Stroink, Hans; Strzelczyk, Adam; Surges, Rainer; Suzuki, Toshimitsu; Tan, K. Meng; Taneja, R. S.; Tanteles, George A.; Tauboll, Erik; Thio, Liu Lin; Thomas, G. Neil; Thomas, Rhys H.; Timonen, Oskari; Tinuper, Paolo; Todaro, Marian; Topaloglu, Pinar; Tozzi, Rossana; Tsai, Meng-Han; Tumiene, Birute; Turkdogan, Dilsad; Unnsteinsdottir, Unnur; Utkus, Algirdas; Vaidiswaran, Priya; Valton, Luc; van Baalen, Andreas; Vetro, Annalisa; Vining, Eileen P. G.; Visscher, Frank; von Brauchitsch, Sophie; von Wrede, Randi; Wagner, Ryan G.; Weber, Yvonne G.; Weckhuysen, Sarah; Weisenberg, Judith; Weller, Michael; Widdess-Walsh, Peter; Wolff, Markus; Wolking, Stefan; Wu, David; Yamakawa, Kazuhiro; Yang, Wanling; Yapici, Zuhal; Yucesan, Emrah; Zagaglia, Sara; Zahnert, Felix; Zara, Federico; Zhou, Wei; Zimprich, Fritz; Zsurka, Gabor; Ali, Quratulain Zulfiqar 分享 收藏
分享 收藏
Transcript specific regulation of expression influences susceptibility to multiple sclerosis Ban, Maria; Liao, Wenjia; Baker, Amie; Compston, Alastair; Thorpe, John; Molyneux, Paul; Fraser, Mary; Khadake, Jyoti; Jones, Joanne; Coles, Alasdair; Sawcer, Stephen 分享 收藏
Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies 全基因组巨型分析确定了16个基因座，并突出了常见癫痫的不同生物学机制 Abou-Khalil, Bassel; Auce, Pauls; Avbersek, Andreja; Bahlo, Melanie; Balding, David J.; Bast, Thomas; Baum, Larry; Becker, Albert J.; Becker, Felicitas; Berghuis, Bianca; Berkovic, Samuel F.; Boysen, Katja E.; Bradfield, Jonathan P.; Brody, Lawrence C.; Buono, Russell J.; Campbell, Ellen; Cascino, Gregory D.; Catarino, Claudia B.; Cavalleri, Gianpiero L.; Cherny, Stacey S.; Chinthapalli, Krishna; Coffey, Alison J.; Compston, Alastair; Coppola, Antonietta; Cossette, Patrick; Craig, John J.; de Haan, Gerrit-Jan; De Jonghe, Peter; de Kovel, Carolien G. F.; Delanty, Norman; Depondt, Chantal; Devinsky, Orrin; Dlugos, Dennis J.; Doherty, Colin P.; Elger, Christian E.; Eriksson, Johan G.; Ferraro, Thomas N.; Feucht, Martha; Francis, Ben; Franke, Andre; French, Jacqueline A.; Freytag, Saskia; Gaus, Verena; Geller, Eric B.; Gieger, Christian; Glauser, Tracy; Glynn, Simon; Goldstein, David B.; Gui, Hongsheng; Guo, Youling; Haas, Kevin F.; Hakonarson, Hakon; Hallmann, Kerstin; Haut, Sheryl; Heinzen, Erin L.; Helbig, Ingo; Hengsbach, Christian; Hjalgrim, Helle; Iacomino, Michele; Ingason, Andres; Jamnadas-Khoda, Jennifer; Johnson, Michael R.; Kalviainen, Reetta; Kantanen, Anne-Mari; Kasperaviciute, Dalia; Trenite, Dorothee Kasteleijn-Nolst; Kirsch, Heidi E.; Knowlton, Robert C.; Koeleman, Bobby P. C.; Krause, Roland; Krenn, Martin; Kunz, Wolfram S.; Kuzniecky, Ruben; Kwan, Patrick; Lal, Dennis; Lau, Yu-Lung; Lehesjoki, Anna-Elina; Lerche, Holger; Leu, Costin; Lieb, Wolfgang; Lindhout, Dick; Lo, Warren D.; Lopes-Cendes, Iscia; Lowenstein, Daniel H.; Malovini, Alberto; Marson, Anthony G.; Mayer, Thomas; McCormack, Mark; Mills, James L.; Mirza, Nasir; Moerzinger, Martina; Moller, Rikke S.; Molloy, Anne M.; Muhle, Hiltrud; Newton, Mark; Ng, Ping-Wing; Noethen, Markus M.; Nuernberg, Peter; O'Brien, Terence J.; Oliver, Karen L.; Palotie, Aarno; Pangilinan, Faith; Peter, Sarah; Petrovski, Slave; Poduri, Annapurna; Privitera, Michael; Radtke, Rodney; Rau, Sarah; Reif, Philipp S.; Reinthaler, Eva M.; Rosenow, Felix; Sander, Josemir W.; Sander, Thomas; Scattergood, Theresa; Schachter, Steven C.; Schankin, Christoph J.; Scheffer, Ingrid E.; Schmitz, Bettina; Schoch, Susanne; Sham, Pak C.; Shih, Jerry J.; Sills, Graeme J.; Sisodiya, Sanjay M.; Slattery, Lisa; Smith, Alexander; Smith, David F.; Smith, Michael C.; Smith, Philip E.; Sonsma, Anja C. M.; Speed, Doug; Sperling, Michael R.; Steinhoff, Bernhard J.; Stephani, Ulrich; Stevelink, Remi; Strauch, Konstantin; Striano, Pasquale; Stroink, Hans; Surges, Rainer; Tan, K. Meng; Thio, Liu Lin; Thomas, G. Neil; Todaro, Marian; Tozzi, Rossana; Vari, Maria S.; Vining, Eileen P. G.; Visscher, Frank; von Spiczak, Sarah; Walley, Nicole M.; Weber, Yvonne G.; Wei, Zhi; Weisenberg, Judith; Whelan, Christopher D.; Widdess-Walsh, Peter; Wolff, Markus; Wolking, Stefan; Yang, Wanling; Zara, Federico; Zimprich, Fritz 分享 收藏
分享 收藏
分享 收藏
分享 收藏
No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis Goris, An; van Setten, Jessica; Diekstra, Frank; Ripke, Stephan; Patsopoulos, Nikolaos A.; Sawcer, Stephen J.; van Es, Michael; Andersen, Peter M.; Melki, Judith; Meininger, Vincent; Hardiman, Orla; Landers, John E.; Brown, Robert H., Jr.; Shatunov, Aleksey; Leigh, Nigel; Al-Chalabi, Ammar; Shaw, Christopher E.; Traynor, Bryan J.; Chio, Adriano; Restagno, Gabriella; Mora, Gabriele; Ophoff, Roel A.; Oksenberg, Jorge R.; Van Damme, Philip; Compston, Alastair; Robberecht, Wim; Dubois, Benedicte; van den Berg, Leonard H.; De Jager, Philip L.; Veldink, Jan H.; de Bakker, Paul I. W. 分享 收藏
分享 收藏
MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis Lill, Christina M.; Schjeide, Brit-Maren M.; Graetz, Christiane; Ban, Maria; Alcina, Antonio; Ortiz, Miguel A.; Perez, Jennifer; Damotte, Vincent; Booth, David; Lopez de lapuente, Aitzkoa; Broer, Linda; Schilling, Marcel; Akkad, Denis A.; Aktas, Orhan; Alloza, Iraide; Antigueedad, Alfredo; Arroyo, Rafa; Blaschke, Paul; Buttmann, Mathias; Chan, Andrew; Compston, Alastair; Cournu-Rebeix, Isabelle; Doerner, Thomas; Epplen, Joerg T.; Fernandez, Oscar; Gerdes, Lisa-Ann; Guillot-Noel, Lena; Hartung, Hans-Peter; Hoffjan, Sabine; Izquierdo, Guillermo; Kemppinen, Anu; Kroner, Antje; Kubisch, Christian; Kuempfel, Tania; Li, Shu-Chen; Lindenberger, Ulman; Lohse, Peter; Lubetzki, Catherine; Luessi, Felix; Malhotra, Sunny; Mescheriakova, Julia; Montalban, Xavier; Papeix, Caroline; Paredes, Lidia F.; Rieckmann, Peter; Steinhagen-Thiessen, Elisabeth; Winkelmann, Alexander; Zettl, Uwe K.; Hintzen, Rogier; Vandenbroeck, Koen; Stewart, Graeme; Fontaine, Bertrand; Comabella, Manuel; Urcelay, Elena; Matesanz, Fuencisla; Sawcer, Stephen; Bertram, Lars; Zipp, Frauke 分享 收藏
Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex Zuvich, Rebecca L.; Bush, William S.; McCauley, Jacob L.; Beecham, Ashley H.; De Jager, Philip L.; Ivinson, Adrian J.; Compston, Alastair; Hafler, David A.; Hauser, Stephen L.; Sawcer, Stephen J.; Pericak-Vance, Margaret A.; Barcellos, Lisa F.; Mortlock, Douglas P.; Haines, Jonathan L. 分享 收藏
分享 收藏
Derivation of neural precursor cells from human ES cells at 3% O2 is efficient, enhances survival and presents no barrier to regional specification and functional differentiation Stacpoole, S. R. L.; Bilican, B.; Webber, D. J.; Luzhynskaya, A.; He, X. L.; Compston, A.; Karadottir, R.; Franklin, R. J. M.; Chandran, S. 分享 收藏
分享 收藏
分享 收藏
Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility Zuvich, Rebecca L.; McCauley, Jacob L.; Oksenberg, Jorge R.; Sawcer, Stephen J.; De Jager, Philip L.; Aubin, Cristin; Cross, Anne H.; Piccio, Laura; Aggarwal, Neelum T.; Evans, Denis; Hafler, David A.; Compston, Alastair; Hauser, Stephen L.; Pericak-Vance, Margaret A.; Haines, Jonathan L. 分享 收藏
Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci McCauley, Jacob L.; Zuvich, Rebecca L.; Beecham, Ashley H.; De Jager, Philip L.; Konidari, Ioanna; Whitehead, Patrice L.; Aubin, Cristin; Ban, Maria; Pobywajlo, Susan; Briskin, Rebeccah; Romano, Susan; Aggarwal, Neelum T.; Piccio, Laura; McArdle, Wendy L.; Strachan, David P.; Evans, Denis; Cross, Anne H.; Cree, Bruce; Rioux, John D.; Barcellos, Lisa F.; Ivinson, Adrian J.; Compston, Alastair; Hafler, David A.; Hauser, Stephen L.; Oksenberg, Jorge R.; Sawcer, Stephen J.; Pericak-Vance, Margaret A.; Haines, Jonathan L. 分享 收藏
The role of the CD58 locus in multiple sclerosis De Jager, Philip L.; Baecher-Allan, Clare; Maier, Lisa M.; Arthur, Ariel T.; Ottoboni, Linda; Barcellos, Lisa; McCauley, Jacob L.; Sawcer, Stephen; Goris, An; Saarela, Janna; Yelensky, Roman; Price, Alkes; Leppa, Virpi; Patterson, Nick; de Bakker, Paul I. W.; Tran, Dong; Aubin, Cristin; Pobywajlo, Susan; Rossin, Elizabeth; Hu, Xinli; Ashley, Charles W.; Choy, Edwin; Rioux, John D.; Pericak-Vance, Margaret A.; Ivinson, Adrian; Booth, David R.; Stewart, Graeme J.; Palotie, Aarno; Peltonen, Leena; Dubois, Benedicte; Haines, Jonathan L.; Weiner, Howard L.; Compston, Alastair; Hauser, Stephen L.; Daly, Mark J.; Reich, David; Oksenberg, Jorge R.; Hafler, David A. 分享 收藏
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants 四种疾病中14,500个非同义snp的关联扫描可识别自身免疫变异 Newport, Melanie; Sirugo, Giorgio; Lyons, Emily; Vannberg, Fredrik; Hill, Adrian V. S.; Bradbury, Linda A.; Farrar, Claire; Pointon, Jennifer J.; Wordsworth, Paul; Brown, Matthew A.; Franklyn, Jayne A.; Heward, Joanne M.; Simmonds, Matthew J.; Gough, Stephen C. L.; Seal, Sheila; Stratton, Michael R.; Rahman, Nazneen; Ban, Maria; Goris, An; Sawcer, Stephen J.; Compston, Alastair; Conway, David; Jallow, Muminatou; Newport, Melanie; Sirugo, Giorgio; Rockett, Kirk A.; Kwiatkowski, Dominic P.; Bumpstead, Suzannah J.; Chaney, Amy; Downes, Kate; Ghori, Mohammed J. R.; Gwilliam, Rhian; Hunt, Sarah E.; Inouye, Michael; Keniry, Andrew; King, Emma; McGinnis, Ralph; Potter, Simon; Ravindrarajah, Rathi; Whittaker, Pamela; Widden, Claire; Withers, David; Deloukas, Panos; Leung, Hin-Tak; Nutland, Sarah; Stevens, Helen E.; Walker, Neil M.; Todd, John A.; Easton, Doug; Clayton, David G.; Burton, Paul R.; Tobin, Martin D.; Barrett, Jeffrey C.; Evans, David M.; Morris, Andrew P.; Cardon, Lon R.; Cardin, Niall J.; Davison, Dan; Ferreira, Teresa; Pereira-Gale, Joanne; Hallgrimsdottir, Ingeleif B.; Howie, Bryan N.; Marchini, Jonathan L.; Spencer, Chris C. A.; Su, Zhan; Teo, Yik Ying; Vukcevic, Damjan; Donnelly, Peter; Bentley, David; Brown, Matthew A.; Cardon, Lon R.; Caulfield, Mark; Clayton, David G.; Compston, Alastair; Craddock, Nick; Deloukas, Panos; Donnelly, Peter; Farrall, Martin; Barton, Anne; Bruce, Ian N.; Donovan, Hannah; Eyre, Steve; Gilbert, Paul D.; Hilder, Samantha L.; Hinks, Anne M.; John, Sally L.; Potter, Catherine; Silman, Alan J.; Symmons, Deborah P. M.; Thomson, Wendy; Worthington, Jane; Gough, Stephen C. L.; Hall, Alistair S.; Hattersley, Andrew T.; Hill, Adrian V. S.; Kwiatkowski, Dominic P.; Matthew, Christopher G.; McCarthy, Mark I.; Ouwehand, Willem H.; Parkes, Miles; Pembrey, Marcus; Rahman, Nazneen; Samani, Nilesh J.; Stratton, Michael R.; Todd, John A.; Worthington, Jane; Mitchell, Sarah L.; Newby, Paul R.; Brand, Oliver J.; Carr-Smith, Jackie; Pearce, Simon H. S.; Gough, Stephen C. L.; McGinnis, R.; Keniry, A.; Deloukas, P.; Reveille, John D.; Zhou, Xiaodong; Bradbury, Linda A.; Sims, Anne-Marie; Dowling, Alison; Taylor, Jacqueline; Doan, Tracy; Cardon, Lon R.; Davis, John C.; Pointon, Jennifer J.; Savage, Laurie; Ward, Michael M.; Learch, Thomas L.; Weisman, Michael H.; Wordsworth, Paul; Brown, Matthew A. 分享 收藏
Tau and α-synuclein in susceptibility to, and dementia in, Parkinson's disease Goris, An; Williams-Gray, Caroline H.; Clark, Graeme R.; Foltynie, Thomas; Lewis, Simon J. G.; Brown, Joanne; Ban, Maria; Spillantini, Maria G.; Compston, Alastair; Burn, David J.; Chinnery, Patrick F.; Barker, Roger A.; Sawcer, Stephen J. 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
