Fionula M. Brennan - Publications, H-index & Citations

Fionula M. Brennan

university of oxford

79H指数

250论文数

2.1W被引数

收录论文 46

发表时间

Novel biomarkers of a peripheral blood interferon signature associated with drug-naive early arthritis patients distinguish persistent from self-limiting disease course

SCIENTIFIC REPORTS

IF3.9

2020-06-01

OAAI

Seyhan, Attila A.; Gregory, Bernard; Cribbs, Adam P.; Bhalara, Sundeept; Li, Yizheng; Loreth, Christine; Zhang, Ying; Guo, Yongjing; Lin, Lih-Ling; Feldmann, Marc; Williams, Lynn M.; Brennan, Fionula M.; Taylor, Peter C.

Methotrexate Restores Regulatory T Cell Function Through Demethylation of the FoxP3 Upstream Enhancer in Patients With Rheumatoid Arthritis

ARTHRITIS & RHEUMATOLOGY

IF10.9

2015-04-27

133

PREAI

Cribbs, Adam P.; Kennedy, Alan; Penn, Henry; Amjadi, Parisa; Green, Patricia; Read, Jordan E.; Brennan, Fionula; Gregory, Bernard; Williams, Richard O.

Design and Optimisation of Bioactive Cyclic Peptides: Generation of a Down-Regulator of TNF Secretion

MOLECULES

IF4.6

2014-12-22

OAAI

New, Roger; Bansal, Gurpal S.; Dryjska, Malgorzata; Bogus, Michal; Green, Patricia; Feldmann, Marc; Brennan, Fionula

Treg Cell Function in Rheumatoid Arthritis Is Compromised by CTLA-4 Promoter Methylation Resulting in a Failure to Activate the Indoleamine 2,3-Dioxygenase Pathway

ARTHRITIS & RHEUMATOLOGY

IF10.9

2014-08-26

129

PREAI

Cribbs, Adam P.; Kennedy, Alan; Penn, Henry; Read, Jordan E.; Amjadi, Parisa; Green, Patricia; Syed, Khaja; Manka, Szymon W.; Brennan, Fionula M.; Gregory, Bernard; Williams, Richard O.

Simplified production and concentration of lentiviral vectors to achieve high transduction in primary human T cells

BMC BIOTECHNOLOGY

IF3.4

2013-11-12

131

OAAI

Cribbs, Adam P.; Kennedy, Alan; Gregory, Bernard; Brennan, Fionula M.

BLOCKING THE INHIBITORY CD94/NKG2A NK CELL RECEPTOR WITH A NOVEL ANTI-NKG2A MAB ENHANCES THE SUSCEPTIBILITY OF RHEUMATOID ARTHRITIS FIBROBLAST-LIKE SYNOVIOCYTES (FLS) TO NK CELL-MEDIATED CYTOTOXICITY

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2012-06-01

PREAI

Nielsen, N.; Galsgaard, E. D.; Ahern, D.; Andersen, M.; Spee, P.; Feldmann, M.; Brennan, F.; Soederstroem, K.

Production of TNF-α in Macrophages Activated by T Cells, Compared with Lipopolysaccharide, Uses Distinct IL-10-Dependent Regulatory Mechanism

JOURNAL OF IMMUNOLOGY

IF3.4

2012-02-01

OAAI

Agbanoma, Gideon; Li, Ching; Ennis, Darren; Palfreeman, Andrew C.; Williams, Lynn M.; Brennan, Fionula M.

Resistance to regulatory T cell-mediated suppression in rheumatoid arthritis can be bypassed by ectopic foxp3 expression in pathogenic synovial T cells 在类风湿关节炎中对调节性T细胞介导的抑制的抗性可以通过致病性滑膜T细胞中的异位foxp3表达来绕过

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-09-16

OAAI

Beavis, Paul A.; Gregory, Bernard; Green, Patricia; Cribbs, Adam P.; Kennedy, Alan; Amjadi, Parisa; Palfreeman, Andrew C.; Feldmann, Marc; Brennan, Fionula M.

The role of Natural Killer cells in the pathogenesis of rheumatoid arthritis: Major contributors or essential homeostatic modulators?

IMMUNOLOGY LETTERS

IF2.8

2011-05-01

PREAI

Ahern, David J.; Brennan, Fionula M.

Nonsteroidal Anti-Inflammatory Drugs Increase TNF Production in Rheumatoid Synovial Membrane Cultures and Whole Blood

JOURNAL OF IMMUNOLOGY

IF3.4

2010-09-15

PREAI

Page, Theresa H.; Turner, Jeremy J. O.; Brown, Anthony C.; Timms, Emma M.; Inglis, Julia J.; Brennan, Fionula M.; Foxwell, Brian M. J.; Ray, Keith P.; Feldmann, Marc

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease

NATURE MEDICINE

IF50

2009-06-28

621

PREAI

Midwood, Kim; Sacre, Sandra; Piccinini, Anna M.; Inglis, Julia; Trebaul, Annette; Chan, Emma; Drexler, Stefan; Sofat, Nidhi; Kashiwagi, Masahide; Orend, Gertraud; Brennan, Fionula; Foxwell, Brian

Inhibitors of TLR8 Reduce TNF Production from Human Rheumatoid Synovial Membrane Cultures

JOURNAL OF IMMUNOLOGY

IF3.4

2008-12-01

OAAI

Sacre, Sandra M.; Lo, Alexandra; Gregory, Bernard; Simmonds, Rachel E.; Williams, Lynn; Feldmann, Marc; Brennan, Fionula M.; Foxwell, Brian M.

Evidence that cytokines play a role in rheumatoid arthritis

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2008-11-03

981

OAAI

Brennan, Fionula M.; McInnes, Iain B.

TREM-1 expression is increased in the Synovium of Rheumatoid Arthritis patients and induces the expression of pro-inflammatory cytokines

CYTOKINE

IF3.7

2008-09-01

PREAI

Kuai, Jun; Gregory, Bernard; Hill, Andrew; Pittman, Debra D.; Feldman, Jeffrey L.; Brown, Tom; Carito, Brenda; OToole, Margot; Ramsey, Renee; Shields, Kathleen M.; Beech, Jonathan T.; Nanchahal, Jagdeep; Feldmann, Marc; Foxwell, Brian M.; Brennan, Fionula M.

Neutralizing IL-21 and IL-15 inhibits pro-inflammatory cytokine production in rheumatoid arthritis

SCANDINAVIAN JOURNAL OF IMMUNOLOGY

IF1.6

2008-05-16

PREAI

Andersson, A. K.; Feldmann, M.; Brennan, F. M.

Rac mediates TNF-induced cytokine production via modulation of NF-κB

MOLECULAR IMMUNOLOGY

IF3

2008-05-01

PREAI

Williams, Lynn A.; Lali, Ferdinand; Willetts, Kate; Balague, Cristina; Godessart, Nuria; Brennan, Fionula; Feldmann, Marc; Foxwell, Brian M. J.