未登录Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells
Indra, Radek; Cerna, Tereza; Heger, Zbynek; Hrabeta, Jan; Wilhelm, Marek; Dostalova, Simona; Lengalova, Alzbeta; Martinkova, Marketa; Adam, Vojtech; Eckschlager, Tomas; Schmeiser, Heinz H.; Arlt, Volker M.; Stiborova, Marie
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收藏Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
Reed, Lindsay; Indra, Radek; Mrizova, Iveta; Moserova, Michaela; Schmeiser, Heinz H.; Wolf, C. Roland; Henderson, Colin J.; Stiborova, Marie; Phillips, David H.; Arlt, Volker M.
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收藏Cytochrome b5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b5/P450 reductase null (HBRN) mice
Reed, Lindsay; Mrizova, Iveta; Barta, Frantisek; Indra, Radek; Moserova, Michaela; Kopka, Klaus; Schmeiser, Heinz H.; Wolf, C. Roland; Henderson, Colin J.; Stiborova, Marie; Phillips, David H.; Arlt, Volker M.
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收藏NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene (vol 29, pg 1325, 2016)
Stiborova, Marie; Indra, Radek; Moserova, Michaela; Frei, Eva; Schmeiser, Heinz H.; Kopka, Klaus; Phillips, David H.; Arlt, Volker M.
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收藏Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone
Arlt, Volker M.; Meinl, Walter; Florian, Simone; Nagy, Eszter; Barta, Frantisek; Thomann, Marlies; Mrizova, Iveta; Krais, Annette M.; Liu, Maggie; Richards, Meirion; Mirza, Amin; Kopka, Klaus; Phillips, David H.; Glatt, Hansruedi; Stiborova, Marie; Schmeiser, Heinz H.
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收藏Long-term Outcome of Kidney Recipients Transplanted for Aristolochic Acid Nephropathy
Kanaan, Nada; Hassoun, Ziad; Raggi, Claudia; Jadoul, Michel; Mourad, Michel; De Meyer, Martine; Aydin, Selda; Schmeiser, Heinz H.; Cosyns, Jean-Pierre; Goffin, Eric
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收藏Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo
Dracinska, Helena; Barta, Frantisek; Levova, Katerina; Hudecova, Alena; Moserova, Michaela; Schmeiser, Heinz H.; Kopka, Klaus; Frei, Eva; Arlt, Volker M.; Stiborova, Marie
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收藏The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/ plus ), Trp53(+/-) and Trp53(-/-) mice
Krais, Annette M.; Speksnijder, Ewoud N.; Melis, Joost P. M.; Indra, Radek; Moserova, Michaela; Godschalk, Roger W.; van Schooten, Frederik-J.; Seidel, Albrecht; Kopka, Klaus; Schmeiser, Heinz H.; Stiborova, Marie; Phillips, David H.; Luijten, Mirjam; Arlt, Volker M.
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收藏Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions在低NADPH:P450氧化还原酶条件下,细胞色素b5和环氧化物水解酶有助于细胞色素P450 1A1催化的苯并 [a] re-DNA加合物的形成
Stiborova, Marie; Moserova, Michaela; Cerna, Vera; Indra, Radek; Dracinsky, Martin; Sulc, Miroslav; Henderson, Colin J.; Wolf, C. Roland; Schmeiser, Heinz H.; Phillips, David H.; Frei, Eva; Arlt, Volker M.
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收藏Exceptionally long- term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy
Schmeiser, Heinz H.; Nortier, Joelle L.; Singh, Rajinder; da Costa, Goncalo Gamboa; Sennesael, Jacques; Cassuto-Viguier, Elisabeth; Ambrosetti, Damien; Rorive, Sandrine; Pozdzik, Agnieszka; Phillips, David H.; Stiborova, Marie; Arlt, Volker M.
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