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C

C. Roland Wolf

university of dundee
H指数:90
被引数:3.2万

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Humanization of Drug Metabolism in the Plasmodium berghei Mouse Model for Antimalarial Drug Discovery

伯氏疟原虫小鼠模型中药物代谢的人源化用于抗疟药物发现

ACS Infectious Diseases
IF3.8
2025-11-300
OAAI
A. Kenneth MacLeod; Cristina Merino; Sara Viera-Morilla; Laura Frame; Amy Tavendale; Christina Duncan; Liam Ferguson; Erika G. Pinto; Frederick R. C. Simeons; Vanessa Gomez-Jimenez; Ana Belén García; Jennifer Riley; Yoko Shishikura; María Santos Martínez- Martínez; C. Roland Wolf; Kevin D. Read
APPLICATION OF A MOUSE MODEL HUMANIZED FOR CYTOCHROME P450-MEDIATED DRUG METABOLISM TO PREDICT DRUG-DRUG INTERACTIONS BETWEEN PEPTIDE AND SMALL MOLECULE DRUGS

构建用于细胞色素P450介导的药物代谢的人源化小鼠模型，以预测肽类药物与小分子药物之间的药物相互作用

Drug Metabolism and Disposition
IF4
2025-08-260
PREAI
Yury Kapelyukh; Charlotte Gabel-Jensen; Alastaire Kenneth MacLeod; Kevin-Sebastien Daniel Coquelin; Laste Stojanovski; Laura Frame; Amy Tavendale; Colin J. Henderson; Kevin D. Read; Charles Roland Wolf; Carolina Säll
The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals

强效的人类CAR激动剂CITCO是人体化组成型雄烷受体小鼠中的非遗传毒性肝肿瘤促进剂，但不是野生型动物中的。

ARCHIVES OF TOXICOLOGY
IF6.9
2025-03-050
OA
Henderson, C. J.; Mclaren, A. W.; Macleod, A. K.; Lin, D.; Cameron, A. R.; Chatham, L. R.; Moggs, J.; Inesta-Vaquera, F.; Thomson, John P.; Meehan, Richard R.; Chakravarty, P.; Schwarz, M.; Wolf, C. Roland
Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism

使用人性化的药物代谢模型加速传染病药物的发现和开发

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-02-053
OAAI
Macleod, Kenneth; Coquelin, Kevin-Sebastien; Huertas, Leticia; Simeons, Frederick R. C.; Riley, Jennifer; Casado, Patricia; Guijarro, Laura; Casanueva, Ruth; Frame, Laura; Pinto, Erika G.; Ferguson, Liam; Duncan, Christina; Mutter, Nicole; Shishikura, Yoko; Henderson, Colin J.; Cebrian, David; Wolf, C. Roland; Read, Kevin D.
The BRandO BiO registry - A multicenter regional registry for patients with primary breast and ovarian cancer with longitudinal biobanking and evaluation of epidemiological, life style and quality of life factors
CANCER RESEARCH
IF16.6
2019-02-150
PRE
Huober, J.; Nagel, G.; Rempen, A.; Schlicht, E.; Flock, F.; Fritz, S.; Thiel, F.; Wiesmuller, L.; Felderbaum, R.; Heilmann, V.; Bekes, I.; Fink, V.; Albrecht, S.; De Gregorio, N.; Tzschaschel, M.; Ernst, K.; Wolf, C.; Kuhn, P.; Friedl, T.; Janni, W.; De Gregorio, A.

研究方向

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C
Colin J. Henderson
H 指数:51论文数:307被引数:1.0万
G
Gillian Smith
H 指数:51论文数:194被引数:1.0万
N
Nico Scheer
H 指数:26论文数:59被引数:3,138
M
Mark J. I. Paine
H 指数:48论文数:161被引数:7,773
G
Gordon C. K. Roberts
H 指数:75论文数:748被引数:1.7万
T
Thomas Friedberg
H 指数:37论文数:126被引数:4,205
L
Lesley A. McLaughlin
H 指数:22论文数:68被引数:1,396
V
Volker M. Arlt
H 指数:59论文数:263被引数:1.1万
D
David H. Phillips
H 指数:87论文数:699被引数:2.8万
Y
Yury Kapelyukh
H 指数:10论文数:26被引数:485