未登录Novel Multikinase Clk Inhibitor BH-30236 Targets Hematological Malignancies through Alternative Splicing Regulation新型多激酶Clk抑制剂BH-30236通过选择性剪接调控靶向血液系统恶性肿瘤
Ling, Nancy; Sims, Gregory; Jiang, Ping; Deng, Wei; Zhai, Dayong; Li, Danan; Wang, Zhenping; Hu, Yue; Wang, Eric; Graber, Armin; Cui, J. Jean
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收藏Repotrectinib in ROS1 Fusion-Positive Non-Small-Cell Lung Cancer罗索替尼在ROS1融合阳性非小细胞肺癌中的应用
Drilon, Alexander; Camidge, D. Ross; Lin, Jessica J.; Kim, Sang-We; Solomon, Benjamin J.; Dziadziuszko, Rafal; Besse, Benjamin; Goto, Koichi; de Langen, Adrianus Johannes; Wolf, Juergen; Lee, Ki Hyeong; Popat, Sanjay; Springfeld, Christoph; Nagasaka, Misako; Felip, Enriqueta; Yang, Nong; Velcheti, Vamsidhar; Lu, Shun; Kao, Steven; Dooms, Christophe; Krebs, Matthew G.; Yao, Wenxiu; Beg, Muhammad Shaalan; Hu, Xiufeng; Moro-Sibilot, Denis; Cheema, Parneet; Stopatschinskaja, Shanna; Mehta, Minal; Trone, Denise; Graber, Armin; Sims, Gregory; Yuan, Yong; Cho, Byoung Chul
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收藏Stem cell mutations can be detected in myeloma patients years before onset of secondary leukemias
Sridharan, Ashwin; Schinke, Carolina D.; Georgiev, George; Ferreira, Mariana Da Silva; Thiruthuvanathan, Victor; MacArthur, Ian; Bhagat, Tushar D.; Choudhary, Gaurav S.; Aluri, Srinivas; Chen, Jiahao; Pradhan, Kith; Xia, Yu; Panjikaran, Maya; Sims, Gregory; Bhagat, Chirag K.; Bender, Ryan; Keeler, Lauryn; Graber, Armin; Heuck, Christoph; Fletcher, Frederick A.; Alapat, Daisy; Weinhold, Niels; Johnson, Sarah K.; Wickrema, Amittha; Barlogie, Bart; Morgan, Gareth J.; Shastri, Aditi; Steidl, Ulrich; Will, Britta; Verma, Amit
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收藏TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC for treatment of cancers with abnormal HGF/MET signaling
Zhai, Dayong; Rogers, Evan; Deng, Wei; Zhang, Xin; Lee, Dong; Ung, Jane; Zhang, Han; Liu, Jing; Lu, Yuelie; Huang, John; Graber, Armin; Zimmerman, Zach; Lim, John; Whitten, Jeffrey; Cui, J. Jean
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收藏TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC inhibits tumor growth by promoting anti-tumor immune responses
Deng, Wei; Zhai, Dayong; Rogers, Evan; Zhang, Xin; Lee, Dong; Ung, Jane; Zhang, Han; Liu, Jing; Lu, Yuelie; Huang, John; Graber, Armin; Zimmerman, Zach; Lim, John; Whitten, Jeffrey; Cui, J. Jean
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收藏Repotrectinib, a next generation TRK inhibitor, overcomes TRK resistance mutations including solvent front, gatekeeper and compound mutations
Drilon, Alexander; Zhai, Dayong; Deng, Wei; Zhang, Xin; Lee, Dong; Rogers, Evan; Whitten, Jeffrey; Huang, Zhongdong; Graber, Armin; Liu, Juliet; Stopatschinskaja, Shanna; Cui, J. Jean; Kim, Dong-Wan; Cho, Byoung Chul; Doebele, Robert C.; Ou, Sai-Hong Ignatius; Lee, Jeeyun; Shaw, Alice T.
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收藏Phase Ib/II combination study of APR-246 and azacitidine (AZA) in patients with TP53 mutant myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML)
Sallman, David A.; DeZern, Amy; Sweet, Kendra; Steensma, David P.; Cluzeau, Thomas; Sekeres, Mikkael; Garcia-Manero, Guillermo; Roboz, Gail; McLemore, Amy; McGraw, Kathy; Puskas, John; Zhang, Ling; Bhagat, Chirag; Graber, Armin; Al Ali, Najla H.; Padron, Eric; Tell, Roger; Lancet, Jeffrey E.; Fenaux, Pierre; List, Alan F.; Komrokji, Rami S.
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收藏Recurrent ESR1 fusion transcripts are associated with endocrine resistance in estrogen receptor positive, HER2 negative breast cancer
Giltnane, Jennifer M.; Balko, Justin M.; Stricker, Thomas L.; Young, Christian; Estrada, M. Valeria; Wagle, Nikhil; van Allen, Eliezer; Mu, X. Jasmine; Sanchez, Violeta; Farley, Jaime; Fitzgerald, Kerry; Graber, Armin; Pinto, Joseph A.; Doimi, Franco; Gomez, Henry; Rizzo, Monica; Julian, Thomas B.; Abramson, Vandana; Mayer, Ingrid; Kelley, Mark; Yenamandra, Ashwini; Wheeler, Ferrin C.; Sanders, Melinda; Garraway, Levi; Meszoely, Ingrid; Arteaga, Carlos L.
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收藏Development of a binary diagnostic immunofluorescence assay by AQUA® technology for accurate detection of HER-2 levels in breast cancer specimens
Chandrasekaran, Lakshmi Krupa; Bordeaux, Jennifer; Beruti, Sue; Dakappagari, Naveen; Nerenberg, Mike; Lameh, Jelveh; Graber, Armin; Rimm, David; Robbins, Bruce; Rao, Nagesh
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收藏Identification of critical steps involved in optimization of next generation sequencing (NGS) using a retrospective meta-analysis of a large clinical testing cohort
Murphy, Danielle A.; Scott, Christopher; Fitzgerald, Kerry; Panjikaran, Maya; Xia, Yu; Graber, Armin; Kines, Julie; Baer, Adam; McGinniss, Matthew; Christiansen, Jason
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收藏Proteome annotations and identifications of the human pulmonary fibroblast
Malmström, J; Larsen, K; Malmström, L; Tufvesson, E; Parker, K; Marchese, J; Williamson, B; Hattan, S; Patterson, D; Martin, S; Graber, A; Juhasz, P; Westergren-Thorsson, G; Marko-Varga, G
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