未登录 Weekly Oral Prophylaxis With MK-8527 Protects Rhesus Macaques From Intrarectal Challenge With Simian-Human Immunodeficiency Virus 每周口服MK-8527预防可保护恒河猴免受经直肠感染人猿免疫缺陷病毒的挑战 Diamond, Tracy L.; Kapoor, Yash; Li, Fangbiao; Wan, Bang-Lin; Boddicker, Melissa A.; Maxwell, Jill W.; Ngo, Winnie; Fontenot, Jane A.; Soileau, Kelly A.; Villinger, Francois J.; Grobler, Jay A.; Wang, Shubing; Fillgrove, Kerry L.; Lange, Henry S.; Asante-Appiah, Ernest 分享 收藏
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Respiratory virus coinfections during the COVID-19 pandemic: epidemiologic analysis and clinical outcomes from the Phase 2/3 molnupiravir trial (MOVe-OUT) Johnson, Matthew G.; Strizki, Julie M.; Jensen, Erin; Cohen, Jonathan; Katlama, Christine; Fishchuk, Roman; Ponce-de-Leon, Alfredo; Fourie, Nyda; Cheng, Chien-Yu; McCoy, Dorothy; Vesnesky, Mary; Norice, Carmelle T.; Zhang, Ying; Williams-Diaz, Angela; Brown, Michelle L.; Carmelitano, Patricia; Grobler, Jay A.; Paschke, Amanda; De Anda, Carisa 分享 收藏
Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1 Balibar, Carl J.; Klein, Daniel J.; Zamlynny, Beata; Diamond, Tracy L.; Fang, Zhiyu; Cheney, Carol A.; Kristoff, Jan; Lu, Meiqing; Bukhtiyarova, Marina; Ou, Yangsi; Xu, Min; Ba, Lei; Carroll, Steven S.; El Marrouni, Abdellatif; Fay, John F.; Forster, Ashley; Goh, Shih Lin; Gu, Meigang; Krosky, Daniel; Rosenbloom, Daniel I. S.; Sheth, Payal; Wang, Deping; Wu, Guoxin; Zebisch, Matthias; Zhao, Tian; Zuck, Paul; Grobler, Jay; Hazuda, Daria J.; Howell, Bonnie J.; Converso, Antonella 分享 收藏
Molnupiravir for the treatment of COVID-19 in immunocompromised participants: efficacy, safety, and virology results from the phase 3 randomized, placebo-controlled MOVe-OUT trial Johnson, Matthew G.; Strizki, Julie M.; Brown, Michelle L.; Wan, Hong; Shamsuddin, Hala H.; Ramgopal, Moti; Florescu, Diana F.; Delobel, Pierre; Khaertynova, Ilsiyar; Flores, Jose F.; Fouche, Leon F.; Chang, Shan-Chwen; Williams-Diaz, Angela; Du, Jiejun; Grobler, Jay A.; Paschke, Amanda; De Anda, Carisa 分享 收藏
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Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients 莫那普韦用于非住院患者的新型冠状病毒肺炎口服治疗 Bernal, A. Jayk; da Silva, M. M. Gomes; Musungaie, D. B.; Kovalchuk, E.; Gonzalez, A.; Delos Reyes, V; Martin-Quiros, A.; Caraco, Y.; Williams-Diaz, A.; Brown, M. L.; Du, J.; Pedley, A.; Assaid, C.; Strizki, J.; Grobler, J. A.; Shamsuddin, H. H.; Tipping, R.; Wan, H.; Paschke, A.; Butterton, J. R.; Johnson, M. G.; De Anda, C. 分享 收藏
Impact of HIV-1 Resistance-Associated Mutations on Susceptibility to Doravirine: Analysis of Real-World Clinical Isolates Asante-Appiah, Ernest; Lai, Johnny; Wan, Hong; Yang, Dongmei; Martin, Elizabeth Anne; Sklar, Peter; Hazuda, Daria; Petropoulos, Christos J.; Walworth, Charles; Grobler, Jay A. 分享 收藏
Safety and pharmacokinetics of islatravir subdermal implant for HIV-1 pre-exposure prophylaxis: a randomized, placebo-controlled phase 1 trial Matthews, Randolph P.; Patel, Munjal; Barrett, Stephanie E.; Haspeslagh, Liesbeth; Reynders, Tom; Zhang, Saijuan; Rottey, Sylvie; Goodey, Adrian; Vargo, Ryan C.; Grobler, Jay A.; Stoch, S. Aubrey; Iwamoto, Marian 分享 收藏
Safety, tolerability, and pharmacokinetics of single- and multiple-dose administration of islatravir (MK-8591) in adults without HIV Matthews, Randolph P.; Ankrom, Wendy; Friedman, Evan; Jackson Rudd, Deanne; Liu, Yang; Mogg, Robin; Panebianco, Deborah; De Lepeleire, Inge; Petkova, Magdalena; Grobler, Jay A.; Stoch, Selwyn Aubrey; Iwamoto, Marian 分享 收藏
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Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing 用于高通量抗病毒筛选和测试的SARS-CoV-2报告复制子的生成 He, Xi; Quan, Shuo; Xu, Min; Rodriguez, Silveria; Goh, Shih Lin; Wei, Jiajie; Fridman, Arthur; Koeplinger, Kenneth A.; Carroll, Steve S.; Grobler, Jay A.; Espeseth, Amy S.; Olsen, David B.; Hazuda, Daria J.; Wang, Dai 分享 收藏
Safety, pharmacokinetics, and antiretroviral activity of islatravir (ISL, MK-8591), a novel nucleoside reverse transcriptase translocation inhibitor, following single-dose administration to treatment-naive adults infected with HIV-1: an open-label, phase 1b, consecutive-panel trial Schuermann, Dirk; Rudd, Deanne Jackson; Zhang, Saijuan; De Lepeleire, Inge; Robberechts, Martine; Friedman, Evan; Keicher, Christian; Hueser, Andreas; Hofmann, Joerg; Grobler, Jay A.; Stoch, S. Aubrey; Iwamoto, Marian; Matthews, Randolph P. 分享 收藏
Once-Weekly Oral Dosing of MK-8591 Protects Male Rhesus Macaques From Intrarectal Challenge With SHIV109CP3 Markowitz, Martin; Gettie, Agegnehu; St Bernard, Leslie; Andrews, Chasity D.; Mohri, Hiroshi; Horowitz, Amir; Grasperge, Brooke F.; Blanchard, James L.; Niu, Tao; Sun, Li; Fillgrove, Kerry; Hazuda, Daria J.; Grobler, Jay A. 分享 收藏
Extended-Duration MK-8591-Eluting Implant as a Candidate for HIV Treatment and Prevention Barrett, Stephanie E.; Teller, Ryan S.; Forster, Seth P.; Li, Li; Mackey, Megan A.; Skomski, Daniel; Yang, Zhen; Fillgrove, Kerry L.; Doto, Gregory J.; Wood, Sandra L.; Lebron, Jose; Grobler, Jay A.; Sanchez, Rosa I.; Liu, Zhen; Lu, Bing; Niu, Tao; Sun, Li; Gindy, Marian E. 分享 收藏
Long-acting formulations for the treatment of latent tuberculous infection: opportunities and challenges Swindells, S.; Siccardi, M.; Barrett, S. E.; Olsen, D. B.; Grobler, J. A.; Podany, A. T.; Nuermberger, E.; Kim, P.; Barry, C. E., III; Owen, A.; Hazuda, D.; Flexner, C. 分享 收藏
Discovery of a Distinct Chemical and Mechanistic Class of Allosteric HIV-1 Integrase Inhibitors with Antiretroviral Activity Burlein, Christine; Wang, Cheng; Xu, Min; Bhatt, Triveni; Stahlhut, Mark; Ou, Yangsi; Adam, Gregory C.; Heath, Jeffrey; Klein, Daniel J.; Sanders, John; Narayan, Kartik; Abeywickrema, Pravien; Heo, Mee Ra; Carroll, Steven S.; Grobler, Jay A.; Sharma, Sujata; Diamond, Tracy L.; Converso, Antonella; Krosky, Daniel J. 分享 收藏
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