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Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy Nguyen, Binh An; Singh, Virender; Afrin, Shumaila; Yakubovska, Anna; Wang, Lanie; Ahmed, Yasmin; Pedretti, Rose; Fernandez-Ramirez, Maria del Carmen; Singh, Preeti; Pekala, Maja; Hernandez, Luis O. Cabrera; Kumar, Siddharth; Lemoff, Andrew; Gonzalez-Prieto, Roman; Sawaya, Michael R.; Eisenberg, David S.; Benson, Merrill Douglas; Saelices, Lorena 分享 收藏
Guidelines and new directions in the therapy and monitoring of ATTRv amyloidosis Ando, Yukio; Adams, David; Benson, Merrill D.; Berk, John L.; Plante-Bordeneuve, Violaine; Coelho, Teresa; Conceicao, Isabel; Ericzon, Bo-Goran; Obici, Laura; Rapezz, Claudio; Sekijima, Yoshiki; Ueda, Mitsuharu; Palladini, Giovanni; Merlini, Giampaolo 分享 收藏
Tissue biopsy for the diagnosis of amyloidosis: experience from some centres Benson, Merrill D.; Berk, John L.; Dispenzieri, Angela; Damy, Thibaud; Gillmore, Julian D.; Hazenberg, Bouke P.; Lavatelli, Francesca; Picken, Maria M.; Roecken, Christoph; Schoenland, Stefan; Ueda, Mitsuharu; Westermark, Per 分享 收藏
Efficacy and safety with >3 years of inotersen treatment for the polyneuropathy of hereditary transthyretin amyloidosis Coelho, Teresa; Whelan, Carol; Conceicao, Isabel; Brannagan, Thomas; Wang, Annabel; Polydefkis, Michael; Dyck, Peter; Plante-Bordeneuve, Violaine; Berk, John; Merlini, Giampaolo; Obici, Laura; Drachman, Brian; Gorevic, Peter; Schmidt, Hartmut; Plana, Josep Maria Campistol; Gamez, Josep; Kristen, Arnt; Mazzeo, Anna; Narayana, Arvind; Olugemo, Kemi; Aquino, Peter; Benson, Merrill; Gertz, Morie 分享 收藏
Design and Rationale of the Global Phase 3 NEURO-TTRansform Study of Antisense Oligonucleotide AKCEA-TTR-LRx (ION-682884-CS3) in Hereditary Transthyretin-Mediated Amyloid Polyneuropathy Coelho, Teresa; Ando, Yukio; Benson, Merrill D.; Berk, John L.; Waddington-Cruz, Marcia; Dyck, Peter J.; Gillmore, Julian D.; Khella, Sami L.; Litchy, William J.; Obici, Laura; Monteiro, Cecilia; Tai, Li-Jung; Viney, Nicholas J.; Buchele, Gustavo; Brambatti, Michela; Jung, Shiangtung W.; O'Dea, Louis St L.; Tsimikas, Sotirios; Schneider, Eugene; Geary, Richard S.; Monia, Brett P.; Gertz, Morie 分享 收藏
Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data Viney, Nicholas J.; Guo, Shuling; Tai, Li-Jung; Baker, Brenda F.; Aghajan, Mariam; Jung, Shiangtung W.; Yu, Rosie Z.; Booten, Sheri; Murray, Heather; Machemer, Todd; Burel, Sebastien; Murray, Sue; Buchele, Gustavo; Tsimikas, Sotirios; Schneider, Eugene; Geary, Richard S.; Benson, Merrill D.; Monia, Brett P. 分享 收藏
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A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH Ueda, Mitsuharu; Okada, Masamitsu; Mizuguchi, Mineyuki; Kluve-Beckerman, Barbara; Kanenawa, Kyosuke; Isoguchi, Aito; Misumi, Yohei; Tasaki, Masayoshi; Ueda, Akihiko; Kanai, Akinori; Sasaki, Ryoko; Masuda, Teruaki; Inoue, Yasuteru; Nomura, Toshiya; Shinriki, Satoru; Shuto, Tsuyoshi; Kai, Hirofumi; Yamashita, Taro; Matsui, Hirotaka; Benson, Merrill D.; Ando, Yukio 分享 收藏
A pair of peptides inhibits seeding of the hormone transporter transthyretin into amyloid fibrils Saelices, Lorena; Nguyen, Binh A.; Chung, Kevin; Wang, Yifei; Ortega, Alfredo; Lee, Ji H.; Coelho, Teresa; Bijzet, Johan; Benson, Merrill D.; Eisenberg, David S. 分享 收藏
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Hereditary transthyretin amyloidosis: baseline characteristics of patients in the NEURO-TTR trial Waddington-Cruz, Marcia; Ackermann, Elizabeth J.; Polydefkis, Michael; Heitner, Stephen B.; Dyck, Peter J.; Barroso, Fabio A.; Wang, Annabel K.; Berk, John L.; Dyck, P. James B.; Monia, Brett P.; Hughes, Steven G.; Tai, Li; Kwoh, T. Jesse; Jung, Shiangtung W.; Coelho, Teresa; Benson, Merrill D.; Gertz, Morie A. 分享 收藏
Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis Benson, M. D.; Waddington-Cruz, M.; Berk, J. L.; Polydefkis, M.; Dyck, P. J.; Wang, A. K.; Plante-Bordeneuve, V.; Barroso, F. A.; Merlini, G.; Obici, L.; Scheinberg, M.; Brannagan, T. H., III; Litchy, W. J.; Whelan, C.; Drachman, B. M.; Adams, D.; Heitner, S. B.; Conceicao, I.; Schmidt, H. H.; Vita, G.; Campistol, J. M.; Gamez, J.; Gorevic, P. D.; Gane, E.; Shah, A. M.; Solomon, S. D.; Monia, B. P.; Hughes, S. G.; Kwoh, T. J.; McEvoy, B. W.; Jung, S. W.; Baker, B. F.; Ackermann, E. J.; Gertz, M. A.; Coelho, T. 分享 收藏
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AA cardiomyopathy Dasgupta, Noel R.; Cummings, Oscar W.; Phillips, Carrie L.; Benson, Merrill D. 分享 收藏