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Phase I Open-Label Study Evaluating the Safety, Pharmacokinetics, and Preliminary Efficacy of Dilpacimab in Patients with Advanced Solid Tumors 评估Dilpacimab在晚期实体瘤患者中的安全性,药代动力学和初步疗效的I期开放标签研究 Gordon, Michael S.; Nemunaitis, John; Barve, Minal; Wainberg, Zev A.; Hamilton, Erika P.; Ramanathan, Ramesh K.; Sledge, George W., Jr.; Yue, Huibin; Morgan-Lappe, Susan E.; Blaney, Martha; Kasichayanula, Sreeneeranj; Motwani, Monica; Wang, Lan; Naumovski, Louie; Strickler, John H. 分享 收藏
Multicohort Retrospective Validation of a Predictive Biomarker for Topoisomerase I Inhibitors Ando, Koji; Ozonoff, Al; Lee, Shin-Yin; Voisine, Michael; Parker, Julian-Taylor; Nakanishi, Ryota; Nishimura, Sho; Yang, Jing; Grace, Zhao; Tran, Ben; Diefenbach, Thomas J.; Maehara, Yoshihiko; Yasui, Hiroshi; Irino, Tomoyuki; Salgia, Ravi; Terashima, Masanori; Gibbs, Peter; Ramanathan, Ramesh K.; Oki, Eiji; Mori, Masaki; Kulke, Matthew; Hartshorn, Kevan; Bharti, Ajit 分享 收藏
Phase Ib Trial of the PI3K Inhibitor Copanlisib Combined with the Allosteric MEK Inhibitor Refametinib in Patients with Advanced Cancer (vol 15, pg 163, 2020) Ramanathan, Ramesh K.; Von Hoff, Daniel D.; Eskens, Ferry; Blumenschein, George, Jr.; Richards, Donald; Genvresse, Isabelle; Reschke, Susanne; Granvil, Camille; Skubala, Adam; Pena, Carol; Mross, Klaus 分享 收藏
Phase Ib Trial of the PI3K Inhibitor Copanlisib Combined with the Allosteric MEK Inhibitor Refametinib in Patients with Advanced Cancer Ramanathan, Ramesh K.; Von Hoff, Daniel D.; Eskens, Ferry; Blumenschein, George, Jr.; Richards, Donald; Genvresse, Isabelle; Reschke, Susanne; Granvil, Camille; Skubala, Adam; Pena, Carol; Mross, Klaus 分享 收藏
Phase I Dose-Escalation and -Expansion Study of Telisotuzumab (ABT-700), an Anti-c-Met Antibody, in Patients with Advanced Solid Tumors Strickler, John H.; LoRusso, Patricia; Salgia, Ravi; Kang, Yoon-Koo; Yen, Chia Jui; Lin, Chia-Chi; Ansell, Peter; Motwani, Monica; Wong, Shekman; Yue, Huibin; Wang, Lan; Reilly, Edward; Afar, Daniel; Naumovski, Louie; Ramanathan, Ramesh K. 分享 收藏
Phase I study of imalumab (BAX69), a fully human recombinant antioxidized macrophage migration inhibitory factor antibody in advanced solid tumours Mahalingam, Devalingam; Patel, Manish R.; Sachdev, Jasgit C.; Hart, Lowell L.; Halama, Niels; Ramanathan, Ramesh K.; Sarantopoulos, John; Voelkel, Dirk; Youssef, Ashraf; de Jong, Floris A.; Tsimberidou, Apostolia Maria 分享 收藏
Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma De Jesus-Acosta, Ana; Sugar, Elizabeth A.; O'Dwyer, Peter J.; Ramanathan, Ramesh K.; Von Hoff, Daniel D.; Rasheed, Zeshaan; Zheng, Lei; Begum, Asma; Anders, Robert; Maitra, Anirban; McAllister, Florencia; Rajeshkumar, N. V.; Yabuuchi, Shinichi; de Wilde, Roeland F.; Batukbhai, Bhavina; Sahin, Ismet; Laheru, Daniel A. 分享 收藏
A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer (vol 120, pg 183, 2019) Gorbunova, Vera; Beck, J. Thaddeus; Hofheinz, Ralf-Dieter; Garcia-Alfonso, Pilar; Nechaeva, Marina; Gracian, Antonio Cubillo; Mangel, Laszlo; Fernandez, Elena Elez; Deming, Dustin A.; Ramanathan, Ramesh K.; Torres, Alison H.; Sullivan, Danielle; Luo, Yan; Berlin, Jordan D. 分享 收藏
A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer Gorbunova, Vera; Beck, J. Thaddeus; Hofheinz, Ralf-Dieter; Garcia-Alfonso, Pilar; Nechaeva, Marina; Gracian, Antonio Cubillo; Mangel, Laszlo; Fernandez, Elena Elez; Deming, Dustin A.; Ramanathan, Ramesh K.; Torres, Alison H.; Sullivan, Danielle; Luo, Yan; Berlin, Jordan D. 分享 收藏
IL-6/STAT3 activation in hepatocytes drives pro-metastatic niche formation in the liver Lee, Jae W.; Thomas, Stacy K.; Komar, Chad A.; Gladney, Whitney L.; Hua, Xia; Xin, Dong; Shaked, Abraham; Borad, Mitesh J.; Ramanathan, Ramesh K.; Ji, Ailing; Webb, Nancy R.; de Beer, Maria C.; de Beer, Frederick C.; Porrett, Paige M.; Beatty, Gregory L. 分享 收藏
A phase 1 dose-escalation study of veliparib with bimonthly FOLFIRI in patients with advanced solid tumours Berlin, Jordan; Ramanathan, Ramesh K.; Strickler, John H.; Subramaniam, Deepa S.; Marshall, John; Kang, Yoon-Koo; Hetman, Robert; Dudley, Matthew W.; Zeng, Jiewei; Nickner, Caroline; Xiong, Hao; Komarnitsky, Philip; Shepherd, Stacie Peacock; Hurwitz, Herbert; Lenz, Heinz-Josef 分享 收藏
Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors Moschos, Stergios J.; Sullivan, Ryan J.; Hwu, Wen-Jen; Ramanathan, Ramesh K.; Adjei, Alex A.; Fong, Peter C.; Shapira-Frommer, Ronnie; Tawbi, Hussein A.; Rubino, Joseph; Rush, Thomas S., III; Zhang, Da; Miselis, Nathan R.; Samatar, Ahmed A.; Chun, Patrick; Rubin, Eric H.; Schiller, James; Long, Brian J.; Dayananth, Priya; Carr, Donna; Kirschmeier, Paul; Bishop, W. Robert; Deng, Yongqi; Cooper, Alan; Shipps, Gerald W.; Moreno, Blanca Homet; Robert, Lidia; Ribas, Antoni; Flaherty, Keith T. 分享 收藏
Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma DeLeon, Thomas T.; Ahn, Daniel H.; Bogenberger, James M.; Anastasiadis, Panos Z.; Arora, Mansi; Ramanathan, Ramesh K.; Aqel, Bashar A.; Vasmatzis, George; Truty, Mark J.; Oklu, Rahmi; Bekaii-Saab, Tanios S.; Borad, Mitesh J. 分享 收藏
Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours (vol 118, pg 156, 2018) Infante, Jeffrey R.; Korn, Ronald L.; Rosen, Lee S.; LoRusso, Patricia; Dychter, Samuel S.; Zhu, Joy; Maneval, Daniel C.; Jiang, Ping; Shepard, H. Michael; Frost, Gregory; Von Hoff, Daniel D.; Borad, Mitesh J.; Ramanathan, Ramesh K. 分享 收藏
Phase I Study of Enavatuzumab, a First-in-Class Humanized Monoclonal Antibody Targeting the TWEAK Receptor, in Patients with Advanced Solid Tumors Lam, Elaine T.; Eckhardt, S. Gail; Messersmith, Wells; Jimeno, Antonio; O'Bryant, Cindy L.; Ramanathan, Ramesh K.; Weiss, Glen J.; Chadha, Manpreet; Oey, Abbie; Ding, Han Ting; Culp, Patricia A.; Keller, Stephan F.; Zhao, Vivian Y.; Tsao, L. Claire; Singhal, Anil; Holen, Kyle D.; Von Hoff, Daniel 分享 收藏
Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours Infante, Jeffrey R.; Korn, Ronald L.; Rosen, Lee S.; LoRusso, Patricia; Dychter, Samuel S.; Zhu, Joy; Maneval, Daniel C.; Jiang, Ping; Shepard, H. Michael; Frost, Gregory; Von Hoff, Daniel D.; Borad, Mitesh J.; Ramanathan, Ramesh K. 分享 收藏
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Phase I dose escalation study of NMS-1286937, an orally available Polo-Like Kinase 1 inhibitor, in patients with advanced or metastatic solid tumors 口服Polo样激酶1抑制剂NMS-1286937在晚期或转移性实体瘤患者中的I期剂量递增研究 Weiss, Glen J.; Jameson, Gayle; Von Hoff, Daniel D.; Valsasina, Barbara; Davite, Cristina; Di Giulio, Claudia; Fiorentini, Francesco; Alzani, Rachele; Carpinelli, Patrizia; Di Sanzo, Alessandro; Galvani, Arturo; Isacchi, Antonella; Ramanathan, Ramesh K. 分享 收藏