A. Benedict Cosimi - Publications, H-index & Citations

A. Benedict Cosimi

University of Nebraska System

80H指数

533论文数

2.3W被引数

收录论文 143

发表时间

Cardiac allograft tolerance can be achieved in nonhuman primates by donor bone marrow and kidney cotransplantation 通过供者骨髓和肾脏共移植，可以在非人灵长类动物中实现心脏移植耐受。

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2025-01-22

PREAI

Tonsho, Makoto; Jane, M. O.; Sommer, Wiebke; Boskovic, Svjetlan; Patel, Parth M.; Becerra, David C.; Miller, Cynthia L.; Rosales, Ivy A.; Colvin, Robert B.; Sachs, David H.; Cosimi, Benedict; Fairchild, Robert L.; Bin, Sofia; Heeger, Peter S.; Allan, James S.

Successful mixed hematopoietic chimerism by Bcl-2 Inhibition and rapamycin encapsulating nanoparticles (ImmTOR) without chemotherapy or total body irradiation in nonhuman primates.

TRANSPLANTATION

IF5

2024-09-16

PREAI

Karadagi, Ahmad; Tomosugi, Toshihide; Otsuka, Ryo; Lassiter, Grace; Cosimi, A. Benedict; Kishimoto, Kei; Kawai, Tatsuo

Revised Siplizumab-based conditioning regimen for combined kidney and bone marrow transplantation improved mixed hematopoietic chimerism with significant enrichment of regulatory T cells

TRANSPLANTATION

IF5

2024-09-16

PREAI

Otsuka, Ryo; Riella, Leonardo, V; Spitzer, Thomas; Crisalli, Kerry; Baysa, Gabriel; Naso, Dana; Reeves, Patrick; Cosimi, A. Benedict; Elias, Nahel; Kawai, Tatsuo

Selective BCL-2 inhibition to promote hematopoietic mixed chimerism and renal allograft tolerance in low-dose cyclophosphamide-based conditioning regimen without myelosuppression

TRANSPLANTATION

IF5

2024-09-16

PREAI

Tomosugi, Toshihide; Karadagi, Ahmad; Otsuka, Ryo; Tomofuji, Katsuhiro; Rosales, Ivy A.; Sogawa, Hiroshi; Cosimi, A. Benedict; Kawai, Tatsuo

Dysfunction of infiltrating cytotoxic CD8+T cells within the graft promotes murine kidney allotransplant tolerance

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-06-18

OAAI

Yokose, Takahiro; Szuter, Edward S.; Rosales, Ivy; Guinn, Michael T.; Liss, Andrew S.; Baba, Taisuke; Ruddy, David A.; Piquet, Michelle; Azzi, Jamil; Cosimi, A. Benedict; Russell, Paul S.; Madsen, Joren C.; Colvin, Robert B.; Alessandrini, Alessandro

Selective Bcl-2 inhibition promotes hematopoietic chimerism and allograft tolerance without myelosuppression in nonhuman primates

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-04-05

OAAI

Sasaki, Hajime; Hirose, Takayuki; Oura, Tetsu; Otsuka, Ryo; Rosales, Ivy; Ma, David; Lassiter, Grace; Karadagi, Ahmad; Tomosugi, Toshihide; Dehnadi, Abbas; Matsunami, Masatoshi; Paul, Susan Raju; Reeves, Patrick M.; Hanekamp, Isabel; Schwartz, Samuel; Colvin, Robert B.; Lee, Hang; Spitzer, Thomas R.; Cosimi, A. Benedict; Cippa, Pietro E.; Fehr, Thomas; Kawai, Tatsuo

The Importance of Bringing Transplantation Tolerance to the Clinic

TRANSPLANTATION

IF5

2021-04-27

OAAI

Cosimi, A. Benedict; Ascher, Nancy L.; Emond, Jean C.; Kaufman, Dixon B.; Madsen, Joren C.; Miller, Joshua; Monaco, Anthony P.; Montgomery, Robert A.; Newell, Kenneth A.; Sanchez-Fueyo, Alberto; Sarwal, Minnie M.; Scandling, John D.; Strober, Samuel; Todo, Satoru; Weir, Matthew R.; Sachs, David H.

Twenty-year Follow-up of Histocompatibility Leukocyte Antigen-matched Kidney and Bone Marrow Cotransplantation for Multiple Myeloma With End-stage Renal Disease: Lessons Learned

TRANSPLANTATION

IF5

2019-11-01

OAAI

Spitzer, Thomas R.; Tolkoff-Rubin, Nina; Cosimi, A. Benedict; McAfee, Steven; Dey, Bimalangshu R.; Chen, Yi-Bin; Delmonico, Francis; Sykes, Megan; Sachs, David H.; Kawai, Tatsuo

Long-term Kinetics of Intragraft Gene Signatures in Renal Allograft Tolerance Induced by Transient Mixed Chimerism

TRANSPLANTATION

IF5

2019-11-01

OAAI

Matsunami, Masatoshi; Rosales, Ivy A.; Adam, Benjamin A.; Oura, Tetsu; Mengel, Michael; Smith, Rex-Neal; Lee, Hang; Cosimi, A. Benedict; Colvin, Robert B.; Kawai, Tatsuo

Addition of Anti-CD40 Monoclonal Antibody to Nonmyeloablative Conditioning With Belatacept Abrogated Allograft Tolerance Despite Induction of Mixed Chimerism

TRANSPLANTATION

IF5

2019-01-01

OAAI

Oura, Tetsu; Hotta, Kiyohiko; Rosales, Ivy; Dehnadi, Abbas; Kawai, Kent; Lee, Hang; Cosimi, A. Benedict; Kawai, Tatsuo

Non-Myeloablative Conditioning with Low-Dose Total Body Irradiation in Place of Cyclophosphamide Induces Mixed Chimerism and Long-Term Immunosuppression Free Allograft Survival without Acute Kidney Injury in HLA Mismatched Kidney Transplantation

TRANSPLANTATION

IF5

2018-07-01

PREAI

Kawai, Tatsuo; Spitzer, Thomas; Tolkoff-Rubin, Nina; Sykes, Megan; Colvin, Robert B.; Sachs, David H.; Cosimi, A. Benedict

Renal Allograft Tolerance for End-Stage Renal Disease Patients with Hematologic Malignancies

TRANSPLANTATION

IF5

2018-07-01

PREAI

Chen, Yi-Bin; Kawai, Tatsuo; Elias, Nahel; Heher, Eliot; Markmann, James F.; Sykes, Megan; Sachs, David H.; Cosimi, A. Benedict; Spitzer, Thomas

Transcriptional Factor FOXP3 in Renal Allograft Biopsies Predicts Tolerance in Non-Human Primates

TRANSPLANTATION

IF5

2018-07-01

PREAI

Matsunami, Masatoshi; Oura, Tetsu; Adam, Benjamin A.; Mengel, Michael; Rosales, Ivy A.; Smith, Rex-Neal; Schoenfeld, David; Cosimi, A. Benedict; Colvin, Robert B.; Kawai, Tatsuo

RNA expression profiling of renal allografts in a nonhuman primate identifies variation in NK and endothelial gene expression

AMERICAN JOURNAL OF TRANSPLANTATION

IF8.2

2018-06-01

OAAI

Smith, R. N.; Adam, B. A.; Rosales, I. A.; Matsunami, M.; Oura, T.; Cosimi, A. B.; Kawai, T.; Mengel, M.; Colvin, R. B.

RNA expression profiling of nonhuman primate renal allograft rejection identifies tolerance

AMERICAN JOURNAL OF TRANSPLANTATION

IF8.2

2018-06-01

OAAI

Smith, R. N.; Matsunami, M.; Adam, B. A.; Rosales, I. A.; Oura, T.; Cosimi, A. B.; Kawai, T.; Mengel, M.; Colvin, R. B.

Preclinical and clinical studies for transplant tolerance via the mixed chimerism approach

HUMAN IMMUNOLOGY

IF2.2

2018-05-01

OAAI

Sasaki, Hajime; Oura, Tetsu; Spitzer, Thomas R.; Chen, Yi-Bin; Madsen, Joren C.; Allan, James; Sachs, David H.; Cosimi, A. B.; Kawai, Tatsuo

Long-term Nonhuman Primate Renal Allograft Survival Without Ongoing Immunosuppression in Recipients of Delayed Donor Bone Marrow Transplantation

TRANSPLANTATION

IF5

2018-04-01

OAAI

Hotta, Kiyohiko; Oura, Tetsu; Dehnadi, Abbas; Boskovic, Svjetlan; Matsunami, Masatoshi; Rosales, Ivy; Smith, Rex N.; Colvin, Robert B.; Cosimi, A. Benedict; Kawai, Tatsuo

Chronic Antibody-Mediated Rejection in Nonhuman Primate Renal Allografts: Validation of Human Histological and Molecular Phenotypes

AMERICAN JOURNAL OF TRANSPLANTATION

IF8.2

2017-11-01

OAAI

Adam, B. A.; Smith, R. N.; Rosales, I. A.; Matsunami, M.; Afzali, B.; Oura, T.; Cosimi, A. B.; Kawai, T.; Colvin, R. B.; Mengel, M.

Prolonged Survival Following Pig-to-Primate Liver Xenotransplantation Utilizing Exogenous Coagulation Factors and Costimulation Blockade

AMERICAN JOURNAL OF TRANSPLANTATION

IF8.2

2017-08-01

OAAI

Shah, J. A.; Patel, M. S.; Elias, N.; Navarro-Alvarez, N.; Rosales, I.; Wilkinson, R. A.; Louras, N. J.; Hertl, M.; Fishman, J. A.; Colvin, R. B.; Cosimi, A. B.; Markmann, J. F.; Sachs, D. H.; Vagefi, P. A.

Chimerism-based tolerance in organ transplantation: preclinical and clinical studies

CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IF3.8

2017-04-20

OAAI

Oura, T.; Cosimi, A. B.; Kawai, T.

研究方向