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SF3B1 mutation accelerates the development of CLL via activation of the mTOR pathway SF3B1突变通过激活mTOR通路加速CLL的发展。 Zhang, Bo; Iyer, Prajish; Jin, Meiling; Ten Hacken, Elisa; Cartun, Zachary J.; Hart, Kevyn L.; Fernandez, Mike; Stevenson, Kristen; Rassenti, Laura; Ghia, Emanuela M.; Kipps, Thomas J.; Neuberg, Donna; Carrasco, Ruben; Chan, Wing C.; Song, Joo Y.; Hu, Yu; Wu, Catherine J.; Wang, Lili 分享 收藏
Genome-wide study identifies novel genes associated with bone toxicities among children with acute lymphoblastic leukemia Zhu, Qianqian; Mambiar, Ram; Schultz, Emily; Gao, Xinyu; Liang, Shuyi; Flamand, Yael; Stevenson, Kristen; Cole, Peter D.; Gennarini, Lisa; Harris, Marian H.; Kahn, Justine M.; Ladas, Elena J.; Athale, Uma H.; Tran, Thai H.; Michon, Bruno; Welch, Jennifer J. G.; Sallan, Stephen E.; Silverman, Lewis B.; Kelly, Kara M.; Yao, Song 分享 收藏
Phase 1b trial of tagraxofusp in combination with azacitidine with or without venetoclax in acute myeloid leukemia Lane, Andrew A.; Garcia, Jacqueline S.; Raulston, Evangeline G.; Garzon, Jada L.; Galinsky, Ilene; Baxter, Emilie W.; Leonard, Rebecca; Deangelo, Daniel J.; Luskin, Marlise R.; Reilly, Christopher R.; Stahl, Maximilian; Stone, Richard M.; Vedula, Rahul S.; Wadleigh, Martha M.; Winer, Eric S.; Mughal, Tariq; Brooks, Christopher; V. Gupta, Ira; Stevenson, Kristen E.; Neuberg, Donna S.; Ren, Siyang; Keating, Julia; Konopleva, Marina; Sten, Anthony; Pemmaraju, Naveen 分享 收藏
TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence Wu, Gongwei; Yoshida, Noriaki; Liu, Jihe; Zhang, Xiaoyang; Xiong, Yuan; Heavican-Foral, Tayla B.; Mandato, Elisa; Liu, Huiyun; Nelson, Geoffrey M.; Yang, Lu; Chen, Renee; Donovan, Katherine A.; Jones, Marcus K.; Roshal, Mikhail; Zhang, Yanming; Xu, Ran; Nirmal, Ajit J.; Jain, Salvia; Leahy, Catharine; Jones, Kristen L.; Stevenson, Kristen E.; Galasso, Natasha; Ganesan, Nivetha; Chang, Tiffany; Wu, Wen-Chao; Louissaint, Abner; Debaize, Lydie; Yoon, Hojong; Dal Cin, Paola; Chan, Wing C.; Ho Sui, Shannan J.; Ng, Samuel Y.; Feldman, Andrew L.; Horwitz, Steven M.; Adelman, Karen; Fischer, Eric S.; Chen, Chun-Wei; Weinstock, David M.; Brown, Myles 分享 收藏
New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation II型JAK2抑制剂的新型支架克服了获得性G993A耐药突变 Arwood, Matthew L.; Liu, Yao; Harkins, Shannon K.; Weinstock, David M.; Yang, Lei; Stevenson, Kristen E.; Plana, Olivia D.; Dong, Jingyun; Cirka, Haley; Jones, Kristen L.; Virtanen, Anniina T.; Gupta, Dikshat G.; Ceas, Amanda; Lawney, Brian; Yoda, Akinori; Leahy, Catharine; Hao, Mingfeng; He, Zhixiang; Choi, Hwan Geun; Wang, Yaning; Silvennoinen, Olli; Hubbard, Stevan R.; Zhang, Tinghu; Gray, Nathanael S.; Li, Loretta S. 分享 收藏
TP63 fusions drive enhancer rewiring, lymphomagenesis, and dependence on EZH2 Wu, Gongwei; Yoshida, Noriaki; Liu, Jihe; Zhang, Xiaoyang; Xiong, Yuan; Heavican-Foral, Tayla; Liu, Huiyun; Nelson, Geoffrey; Yang, Lu; Chen, Renee; Donovan, Katherine; Jones, Marcus; Roshal, Mikhail; Zhang, Yanming; Xu, Ran; Nirmal, Ajit; Jain, Salvia; Leahy, Catharine; Jones, Kristen; Stevenson, Kristen; Galasso, Natasha; Ganesan, Nivetha; Chang, Tiffany; Wu, Wen-Chao; Louissaint, Abner; Debaize, Lydie; Yoon, Hojong; Dal Cin, Paola; Chan, Wing Chan; Sui, Shannan Ho Ho Sui; Ng, Samuel; Feldman, Andrew; Horwitz, Steven M.; Meyerson, Mathew; Adelman, Karen; Fischer, Eric; Chen, Chun-Wei; Weinstock, David; Brown, Myles 分享 收藏
A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis 一种系统方法指出类维生素a在天冬酰胺酶相关的胰腺炎中的治疗作用 Tsai, Cheng-Yu; Saito, Toshie; Sarangdhar, Mayur; Abu-El-Haija, Maisam; Wen, Li; Lee, Bomi; Yu, Mang; Lipata, Den A.; Manohar, Murli; Barakat, Monique T.; Contrepois, Kevin; Tran, Thai Hoa; Theoret, Yves; Bo, Na; Ding, Ying; Stevenson, Kristen; Ladas, Elena J.; Silverman, Lewis B.; Quadro, Loredana; Anthony, Tracy G.; Jegga, Anil G.; Husain, Sohail Z. 分享 收藏
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JAK3 mutations and mitochondrial apoptosis resistance in T-cell acute lymphoblastic leukemia Bodaar, Kimberly; Yamagata, Natsuko; Barthe, Anais; Landrigan, Jack; Chonghaile, Triona Ni; Burns, Melissa; Stevenson, Kristen E.; Devidas, Meenakshi; Loh, Mignon L.; Hunger, Stephen P.; Wood, Brent; Silverman, Lewis B.; Teachey, David T.; Meijerink, Jules P.; Letai, Anthony; Gutierrez, Alejandro 分享 收藏
Genomic profiling of a randomized trial of interferon-a vs hydroxyurea in MPN reveals mutation-specific responses Knudsen, Trine Alma; Skov, Vibe; Stevenson, Kristen; Werner, Lillian; Duke, William; Laurore, Charles; Gibson, Christopher J.; Nag, Anwesha; Thorner, Aaron R.; Wollison, Bruce; Hansen, Dennis Lund; Ellervik, Christina; El Fassi, Daniel; de Stricker, Karin; Ocias, Lukas Frans; Brabrand, Mette; Bjerrum, Ole Weis; Overgaard, Ulrik Malthe; Frederiksen, Mikael; Kristensen, Thomas Kielsgaard; Kruse, Torben A.; Thomassen, Mads; Mourits-Andersen, Torben; Severinsen, Marianne Tang; Stentoft, Jesper; Starklint, Joern; Neuberg, Donna S.; Kjaer, Lasse; Larsen, Thomas Stauffer; Hasselbalch, Hans Carl; Lindsley, R. Coleman; Mullally, Ann 分享 收藏
Whole-transcriptome analysis in acute lymphoblastic leukemia: a report from the DFCI ALL Consortium Protocol 16-001 Thai Hoa Tran; Langlois, Sylvie; Meloche, Caroline; Caron, Maxime; Saint-Onge, Pascal; Rouette, Alexandre; Bataille, Alain R.; Jimenez-Cortes, Camille; Sontag, Thomas; Bittencourt, Henrique; Laverdiere, Caroline; Lavallee, Vincent-Philippe; Leclerc, Jean-Marie; Cole, Peter D.; Gennarini, Lisa M.; Kahn, Justine M.; Kelly, Kara M.; Michon, Bruno; Santiago, Raoul; Stevenson, Kristen E.; Welch, Jennifer J. G.; Schroeder, Kaitlin M.; Koch, Victoria; Cellot, Sonia; Silverman, Lewis B.; Sinnett, Daniel 分享 收藏
Orthopedic toxicities among adolescents and young adults treated in DFCI ALL Consortium Trials Valtis, Yannis K.; Stevenson, Kristen E.; Place, Andrew E.; Silverman, Lewis B.; Vrooman, Lynda M.; Gotti, Giacomo; Brunner, Andrew M.; Nauffal, Mary; DeAngelo, Daniel J.; Luskin, Marlise R. 分享 收藏
Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia Biran, Anat; Yin, Shanye; Kretzmer, Helene; ten Hacken, Elisa; Parvin, Salma; Lucas, Fabienne; Uduman, Mohamed; Gutierrez, Catherine; Dangle, Nathan; Billington, Leah; Regis, Fara Faye; Rassenti, Laura Z.; Mohammad, Arman; Hoffmann, Gabriela Brunsting; Stevenson, Kristen; Zheng, Mei; Witten, Elizabeth; Fernandes, Stacey M.; Tausch, Eugen; Sun, Clare; Stilgenbauer, Stephan; Brown, Jennifer R.; Kipps, Thomas J.; Aster, John C.; Gnirke, Andreas; Neuberg, Donna S.; Letai, Anthony; Wang, Lili; Carrasco, Ruben D.; Meissner, Alexander; Wu, Catherine J. 分享 收藏
Impact of acute lymphoblastic leukemia induction therapy: findings from metabolomics on non-fasted plasma samples from a biorepository Saito, Toshie; Wei, Yue; Wen, Li; Srinivasan, Chaitanya; Wolthers, Benjamin O.; Tsai, Cheng-Yu; Harris, Marian H.; Stevenson, Kristen; Byersdorfer, Craig; Oparaji, Judy-April; Fernandez, Christian; Mukherjee, Amitava; Abu-El-Haija, Maisam; Agnihotri, Sameer; Schmiegelow, Kjeld; Showalter, Megan R.; Fogle, Paul W.; McCulloch, Scott; Contrepois, Kevin; Silverman, Lewis B.; Ding, Ying; Husain, Sohail Z. 分享 收藏
Low-cost transcriptional diagnostic to accurately categorize lymphomas in low- and middle-income countries Valvert, Fabiola; Silva, Oscar; Solorzano-Ortiz, Elizabeth; Puligandla, Maneka; Tala, Marcos Mauricio Siliezar; Guyon, Timothy; Dixon, Samuel L.; Lopez, Nelly; Lopez, Francisco; Alvarado, Cesar Camilo Carias; Terbrueggen, Robert; Stevenson, Kristen E.; Natkunam, Yasodha; Weinstock, David M.; Briercheck, Edward L. 分享 收藏
Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium Pikman, Yana; Tasian, Sarah K.; Sulis, Maria Luisa; Stevenson, Kristen; Blonquist, Traci M.; Winger, Beth Apsel; Cooper, Todd M.; Pauly, Melinda; Maloney, Kelly W.; Burke, Michael J.; Brown, Patrick A.; Gossai, Nathan; McNeer, Jennifer L.; Shukla, Neerav N.; Cole, Peter D.; Kahn, Justine M.; Chen, Jing; Barth, Matthew J.; Magee, Jeffrey A.; Gennarini, Lisa; Adhav, Asmani A.; Clinton, Catherine M.; Ocasio-Martinez, Nicole; Gotti, Giacomo; Li, Yuting; Lin, Shan; Imamovic, Alma; Tognon, Cristina E.; Patel, Tasleema; Faust, Haley L.; Contreras, Cristina F.; Cremer, Anjali; Cortopassi, Wilian A.; Ruiz, Diego Garrido; Jacobson, Matthew P.; Dharia, Neekesh, V; Su, Angela; Robichaud, Amanda L.; Conway, Amy Saur; Tarlock, Katherine; Stieglitz, Elliot; Place, Andrew E.; Puissant, Alexandre; Hunger, Stephen P.; Kim, Annette S.; Lindeman, Neal, I; Gore, Lia; Janeway, Katherine A.; Silverman, Lewis B.; Tyner, Jeffrey W.; Harris, Marian H.; Loh, Mignon L.; Stegmaier, Kimberly 分享 收藏
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes (vol 26, pg 1549, 2020) TP53等位基因状态对骨髓增生异常综合征基因组稳定性、临床表现和预后的影响 (第26卷，1549页，2020) Bernard, Elsa; Nannya, Yasuhito; Hasserjian, Robert P.; Devlin, Sean M.; Tuechler, Heinz; Medina-Martinez, Juan S.; Yoshizato, Tetsuichi; Shiozawa, Yusuke; Saiki, Ryunosuke; Malcovati, Luca; Levine, Max F.; Arango, Juan E.; Zhou, Yangyu; Sole, Francesc; Cargo, Catherine A.; Haase, Detlef; Creignou, Maria; Germing, Ulrich; Zhang, Yanming; Gundem, Gunes; Sarian, Araxe; van de Loosdrecht, Arjan A.; Jadersten, Martin; Tobiasson, Magnus; Kosmider, Olivier; Follo, Matilde Y.; Thol, Felicitas; Pinheiro, Ronald F.; Santini, Valeria; Kotsianidis, Ioannis; Boultwood, Jacqueline; Santos, Fabio P. S.; Schanz, Julie; Kasahara, Senji; Ishikawa, Takayuki; Tsurumi, Hisashi; Takaori-Kondo, Akifumi; Kiguchi, Toru; Polprasert, Chantana; Bennett, John M.; Klimek, Virginia M.; Savona, Michael R.; Belickova, Monika; Ganster, Christina; Palomo, Laura; Sanz, Guillermo; Ades, Lionel; Della Porta, Matteo Giovanni; Smith, Alexandra G.; Werner, Yesenia; Patel, Minal; Viale, Agnes; Vanness, Katelynd; Neuberg, Donna S.; Stevenson, Kristen E.; Menghrajani, Kamal; Bolton, Kelly L.; Fenaux, Pierre; Pellagatti, Andrea; Platzbecker, Uwe; Heuser, Michael; Valent, Peter; Chiba, Shigeru; Miyazaki, Yasushi; Finelli, Carlo; Voso, Maria Teresa; Shih, Lee-Yung; Fontenay, Michaela; Jansen, Joop H.; Cervera, Jose; Atsuta, Yoshiko; Gattermann, Norbert; Ebert, Benjamin L.; Bejar, Rafael; Greenberg, Peter L.; Cazzola, Mario; Hellstrom-Lindberg, Eva; Ogawa, Seishi; Papaemmanuil, Elli 分享 收藏
Genomic landscape of cutaneous follicular lymphomas reveals 2 subgroups with clinically predictive molecular features Zhou, Xiaolong Alan; Yang, Jingyi; Ringbloom, Kimberly G.; Martinez-Escala, Maria Estela; Stevenson, Kristen E.; Wenzel, Alexander T.; Fantini, Damiano; Martin, Haley K.; Moy, Andrea P.; Morgan, Elizabeth A.; Harkins, Shannon; Paxton, Christian N.; Hong, Bo; Andersen, Erica F.; Guitart, Joan; Weinstock, David M.; Cerroni, Lorenzo; Choi, Jaehyuk; Louissaint, Abner, Jr. 分享 收藏
Genetic ancestry and skeletal toxicities among childhood acute lymphoblastic leukemia patients in the DFCI 05-001 cohort Yao, Song; Zhu, Qianqian; Cole, Peter D.; Stevenson, Kristen; Harris, Marian H.; Schultz, Emily; Kahn, Justine M.; Ladas, Elena J.; Athale, Uma H.; Clavell, Luis A.; Laverdiere, Caroline; Leclerc, Jean-Marie; Michon, Bruno; Schorin, Marshall A.; Welch, Jennifer J. G.; Sallan, Stephen E.; Silverman, Lewis B.; Kelly, Kara M. 分享 收藏
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