Michael E. Mendelsohn - Publications, H-index & Citations

Michael E. Mendelsohn

Tufts Medical Center

63H指数

246论文数

2.1W被引数

收录论文 74

发表时间

Novel, Potent, and Highly Selective Calcium/CalmodulinDependent Protein Kinase II (CaMKII) Inhibitors Reduce Substrate Phosphorylation in Rat Hearts and Prolong Survival in a Mouse Model of Severe Heart Failure

CIRCULATION

IF38.6

2023-11-07

PREAI

Takagahara, Shuichi; Harada, Mioko; Asada, Mari; Harada, Masataka; Hirakata, Masao; Surks, Howard K.; Mendelsohn, Michael; Ikeda, Shota

The mitochondrial regulator PGC1α is induced by cGMP-PKG signaling and mediates the protective effects of phosphodiesterase 5 inhibition in heart failure

FEBS LETTERS

IF3

2021-11-19

OAAI

Zhu, Guangshuo; Ueda, Kazutaka; Hashimoto, Masaki; Zhang, Manling; Sasaki, Masayuki; Kariya, Taro; Sasaki, Hideyuki; Kaludercic, Nina; Lee, Dong-Ik; Bedja, Djahida; Gabrielson, Matthew; Yuan, Yuan; Paolocci, Nazareno; Blanton, Robert M.; Karas, Richard H.; Mendelsohn, Michael E.; O'Rourke, Brian; Kass, David A.; Takimoto, Eiki

CRD-733, a Novel PDE9 (Phosphodiesterase 9) Inhibitor, Reverses Pressure Overload-Induced Heart Failure

jacc heart failure

IF8.4

2021-01-01

OAAI

Richards, Daniel A.; Aronovitz, Mark J.; Liu, Peiwen; Martin, Gregory L.; Tam, Kelly; Pande, Suchita; Karas, Richard H.; Bloomfield, Daniel M.; Mendelsohn, Michael E.; Blanton, Robert M.

PDE5 inhibitor efficacy is estrogen dependent in female heart disease

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2014-05-16

OAAI

Sasaki, Hideyuki; Nagayama, Takahiro; Blanton, Robert M.; Seo, Kinya; Zhang, Manling; Zhu, Guangshuo; Lee, Dong I.; Bedja, Djahida; Hsu, Steven; Tsukamoto, Osamu; Takashima, Seiji; Kitakaze, Masafumi; Mendelsohn, Michael E.; Karas, Richard H.; Kass, David A.; Takimoto, Eiki

Endothelial dysfunction and systemic hypertension by selective cGMP-dependent protein kinase I inhibition using novel cell-penetrating peptide delivered in vivo

INTERNATIONAL JOURNAL OF CARDIOLOGY

IF3.2

2013-09-01

PREAI

Poh, Kian-Keong; Lu, Ping; Qin, Gangjian; Silver, Marcy; Losordo, Douglas W.; Mendelsohn, Michael E.; Zhu, Yan

Steroid-sensitive Gene 1 Is a Novel Cyclic GMP-dependent Protein Kinase I Substrate in Vascular Smooth Muscle Cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-08-01

OAAI

Wang, Guang-rong; Surks, Howard K.; Tang, K. Mary; Zhu, Yan; Mendelsohn, Michael E.; Blanton, Robert M.

Identification of Novel Protein Kinase G I alpha Interacting Proteins as Potential Targets To Prevent Cardiac Remodeling

JOURNAL OF CARDIAC FAILURE

IF8.2

2013-08-01

PREAI

Blanton, Robert M.; Lane, Angela; Aronovitz, Mark; Wang, Guang-rong; Thoonen, Robrecht; Davis, Roger; Mendelsohn, Michael; Kass, David; Karas, Richard

Mutation of the Protein Kinase I Alpha Leucine Zipper Domain Produces Hypertension and Progressive Left Ventricular Hypertrophy: A Novel Mouse Model of Age-Dependent Hypertensive Heart Disease

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

IF3.8

2013-05-08

OAAI

Blanton, Robert M.; Takimoto, Eiki; Aronovitz, Mark; Thoonen, Robrecht; Kass, David A.; Karas, Richard H.; Mendelsohn, Michael E.

Direct Binding and Regulation of RhoA Protein by Cyclic GMP-dependent Protein Kinase Iα

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-11-01

OAAI

Kato, Mikio; Blanton, Robert; Wang, Guang-Rong; Judson, Timothy J.; Abe, Yuich; Myoishi, Masafumi; Karas, Richard H.; Mendelsohn, Michael E.

Protein Kinase G Iα Inhibits Pressure Overload-Induced Cardiac Remodeling and Is Required for the Cardioprotective Effect of Sildenafil In Vivo

JOURNAL OF THE AMERICAN HEART ASSOCIATION

IF5.3

2012-09-26

OAAI

Blanton, Robert M.; Takimoto, Eiki; Lane, Angela M.; Aronovitz, Mark; Piotrowski, Robert; Karas, Richard H.; Kass, David A.; Mendelsohn, Michael E.

Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors

NATURE MEDICINE

IF50

2012-08-26

285

OAAI

McCurley, Amy; Pires, Paulo W.; Bender, Shawn B.; Aronovitz, Mark; Zhao, Michelle J.; Metzger, Daniel; Chambon, Pierre; Hill, Michael A.; Dorrance, Anne M.; Mendelsohn, Michael E.; Jaffe, Iris Z.

Reduced Endoglin Activity Limits Cardiac Fibrosis and Improves Survival in Heart Failure

CIRCULATION

IF38.6

2012-06-05

112

OAAI

Kapur, Navin K.; Wilson, Szuhuei; Yunis, Adil A.; Qiao, Xiaoying; Mackey, Emily; Paruchuri, Vikram; Baker, Corey; Aronovitz, Mark J.; Karumanchi, S. Ananth; Letarte, Michelle; Kass, David A.; Mendelsohn, Michael E.; Karas, Richard H.

Aldosterone Regulates Vascular Gene Transcription via Oxidative Stress-Dependent and -Independent Pathways

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2011-08-01

OAAI

Newfell, Brenna G.; Iyer, Lakshmanan K.; Mohammad, Najwa N.; McGraw, Adam P.; Ehsan, Afshin; Rosano, Giuseppe; Huang, Paul L.; Mendelsohn, Michael E.; Jaffe, Iris Z.

Elevated Soluble fms-Like Tyrosine Kinase-1 Levels in Acute Coronary Occlusion

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2011-02-01

PREAI

Kapur, Navin K.; Heffernan, Kevin S.; Yunis, Adil A.; Nguyen, Tuan A.; Aronovitz, Mark J.; Parpos, Peter; Wilson, Szuhuei; Baker, Corey K.; Esposito, Michele L.; Shah, Ameer; Kimmelstiel, Carey D.; Weintraub, Andrew; Karas, Richard H.; Mendelsohn, Michael E.

Role of Toll-Like Receptor 4 in Intimal Foam Cell Accumulation in Apolipoprotein E-Deficient Mice

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2011-01-01

127

OAAI

Higashimori, Mie; Tatro, Jeffrey B.; Moore, Kathryn J.; Mendelsohn, Michael E.; Galper, Jonas B.; Beasley, Debbie

Placental growth factor mediates aldosterone-dependent vascular injury in mice

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2010-11-01

OAAI

Jaffe, Iris Z.; Newfell, Brenna G.; Aronovitz, Mark; Mohammad, Najwa N.; McGraw, Adam P.; Perreault, Roger E.; Carmeliet, Peter; Ehsan, Afshin; Mendelsohn, Michael E.

Renal Actions of RGS2 Control Blood Pressure

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IF9.4

2010-11-01

OAAI

Gurley, Susan B.; Griffiths, Robert C.; Mendelsohn, Michael E.; Karas, Richard H.; Coffman, Thomas M.

Rapid progress for non-nuclear estrogen receptor signaling

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2010-07-01

OAAI

Mendelsohn, Michael E.; Karas, Richard H.

Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2009-01-05

193

OAAI

Takimoto, Eiki; Koitabashi, Norimichi; Hsu, Steven; Ketner, Elizabeth A.; Zhang, Manling; Nagayarna, Takahiro; Bedja, Djahida; Gabrielson, Kathleen L.; Blanton, Robert; Siderovski, David P.; Mendelsohn, Michael E.; Kass, David A.

The KCNMB1 E65K variant is associated with reduced central pulse pressure in the community-based Framingham Offspring Cohort

JOURNAL OF HYPERTENSION

IF4.1

2009-01-01

OAAI

Kelley-Hedgepeth, Alyson; Peter, Inga; Montefusco, Maria Claudia; Levy, Daniel; Benjamin, Emelia J.; Vasan, Ramachandran S.; Mendelsohn, Michael E.; Housman, David; Huggins, Gordon S.; Mitchell, Gary F.

研究方向