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J

John B. Harley

us department of veterans affairs medical center

83H指数
456论文数
2.5W被引数
收录论文 104
发表时间
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosusEB病毒在系统性红斑狼疮中重编程自身反应性B细胞作为抗原呈递细胞
err2025-11-12
err0
PREAI
errShady Younis; Salvinaz I. Moutusy; Sajede Rasouli; Shaghayegh Jahanbani; Mahesh Pandit; Xiaohao Wu; Suman Acharya; Orr Sharpe; Tilini U. Wijeratne; Marlayna L. Harris; Emily Y. Yang; Yashaar Chaichian; Shima Parsafar; Matthew C. Baker; John B. Harley; Eric Meffre; Lawrence Steinman; Ann Marshak-Rothstein; Judith A. James; Olivia M. Martinez; Paul J. Utz; Dana E. Orange; Tobias V. Lanz; William H. Robinson
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Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically Unaffected Relatives and Unaffected, Unrelated Individuals
err2022-06-03
err1
errOAAI
errMunroe, Melissa E.; Young, Kendra A.; Guthridge, Joel M.; Kamen, Diane L.; Gilkeson, Gary S.; Weisman, Michael H.; Ishimori, Mariko L.; Wallace, Daniel J.; Karp, David R.; Harley, John B.; Norris, Jill M.; James, Judith A.
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A High Prevalence of Anti-EBNA1 Heteroantibodies in Systemic Lupus Erythematosus (SLE) Supports Anti-EBNA1 as an Origin for SLE Autoantibodies
err2022-02-17
err12
errOAAI
errLaurynenka, Viktoryia; Ding, Lili; Kaufman, Kenneth M.; James, Judith A.; Harley, John B.
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Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles
err2022-02-13
err18
errOAAI
errFechtner, Sabrina; Berens, Heather; Bemis, Elizabeth; Johnson, Rachel L.; Guthridge, Carla J.; Carlson, Nichole E.; Demoruelle, M. Kristen; Harley, John B.; Edison, Jess D.; Norris, Jill A.; Robinson, William H.; Deane, Kevin D.; James, Judith A.; Holers, V. Michael
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Lupus Susceptibility Region Containing CDKN1B rs34330 Mechanistically Influences Expression and Function of Multiple Target Genes, Also Linked to Proliferation and Apoptosis
err2021-10-29
err11
errOAAI
errSingh, Bhupinder; Maiti, Guru P.; Zhou, Xujie; Fazel-Najafabadi, Mehdi; Bae, Sang-Cheol; Sun, Celi; Terao, Chikashi; Okada, Yukinori; Chua, Kek Heng; Kochi, Yuta; Guthridge, Joel M.; Zhang, Hong; Weirauch, Matthew; James, Judith A.; Harley, John B.; Varshney, Gaurav K.; Looger, Loren L.; Nath, Swapan K.
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Global discovery of lupus genetic risk variant allelic enhancer activity
err2021-03-12
err40
errOAAI
errLu, Xiaoming; Chen, Xiaoting; Forney, Carmy; Donmez, Omer; Miller, Daniel; Parameswaran, Sreeja; Hong, Ted; Huang, Yongbo; Pujato, Mario; Cazares, Tareian; Miraldi, Emily R.; Ray, John P.; de Boer, Carl G.; Harley, John B.; Weirauch, Matthew T.; Kottyan, Leah C.
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Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus
err2020-10-15
err19
errOAAI
errDominguez, Daniela; Kamphuis, Sylvia; Beyene, Joseph; Wither, Joan; Harley, John B.; Blanco, Irene; Vila-Inda, Catarina; Brunner, Hermine; Klein-Gitleman, Marissa; McCurdy, Deborah; Wahezi, Dawn M.; Lehman, Thomas; Jelusic, Marija; Peschken, Christine A.; Pope, Janet E.; Gladman, Dafna D.; Hanly, John G.; Clarke, Ann E.; Bernatsky, Sasha; Pineau, Christian; Smith, C. Douglas; Barr, Susan; Boire, Gilles; Rich, Eric; Silverman, Earl D.
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Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome-Wide Association Study and Inverse Variance-Weighted Meta-Analysis类风湿性关节炎遗传易感性的多效性: 一项全表型关联研究和逆方差加权Meta分析
err2020-08-06
err7
errOAAI
errKawai, Vivian K.; Shi, Mingjian; Feng, Qiping; Chung, Cecilia P.; Liu, Ge; Cox, Nancy J.; Jarvik, Gail P.; Lee, Ming T. M.; Hebbring, Scott J.; Harley, John B.; Kaufman, Kenneth M.; Namjou, Bahram; Larson, Eric; Gordon, Adam S.; Roden, Dan M.; Stein, C. Michael; Mosley, Jonathan D.
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Novel genetic associations with interferon in systemic lupus erythematosus identified by replication and fine-mapping of trait-stratified genome-wide screen通过性状分层全基因组筛选的复制和精细定位确定系统性红斑狼疮中干扰素的新遗传关联
err2020-08-01
err19
errOAAI
errGhodke-Puranik, Yogita; Imgruet, Molly; Dorschner, Jessica M.; Shrestha, Prakriti; McCoy, Kaci; Kelly, Jennifer A.; Marion, Miranda; Guthridge, Joel M.; Langefeld, Carl D.; Harley, John B.; James, Judith A.; Sivils, Kathy L.; Niewold, Timothy B.
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Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis
err2019-10-21
err46
errOAAI
errHarris, Valerie M.; Koelsch, Kristi A.; Kurien, Biji T.; Harley, Isaac T. W.; Wren, Jonathan D.; Harley, John B.; Scofield, R. Hal
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Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians
err2019-04-25
err38
errOAAI
errMolineros, Julio E.; Looger, Loren L.; Kim, Kwangwoo; Okada, Yukinori; Terao, Chikashi; Sun, Celi; Zhou, Xu-jie; Raj, Prithvi; Kochi, Yuta; Suzuki, Akari; Akizuki, Shuji; Nakabo, Shuichiro; Bang, So-Young; Lee, Hye-Soon; Kang, Young Mo; Suh, Chang-Hee; Chung, Won Tae; Park, Yong-Beom; Choe, Jung-Yoon; Shim, Seung-Cheol; Lee, Shin-Seok; Zuo, Xiaoxia; Yamamoto, Kazuhiko; Li, Quan-Zhen; Shen, Nan; Porter, Lauren L.; Harley, John B.; Chua, Kek Heng; Zhang, Hong; Wakeland, Edward K.; Tsao, Betty P.; Bae, Sang-Cheol; Nath, Swapan K.
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Genetic influences on susceptibility to rheumatoid arthritis in African-Americans
err2018-11-13
err53
errOAAI
errLaufer, Vincent A.; Tiwari, Hemant K.; Reynolds, Richard J.; Danila, Maria I.; Wang, Jelai; Edberg, Jeffrey C.; Kimberly, Robert P.; Kottyan, Leah C.; Harley, John B.; Mikuls, Ted R.; Gregersen, Peter K.; Absher, Devin M.; Langefeld, Carl D.; Arnett, Donna K.; Bridges, S. Louis, Jr.
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Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis
err2018-04-19
err42
errOAAI
errSherrill, Joseph D.; Kiran, K. C.; Wang, Xinjian; Wen, Ting; Chamberlin, Adam; Stucke, Emily M.; Collins, Margaret H.; Abonia, J. Pablo; Peng, Yanyan; Wu, Qiang; Putnam, Philip E.; Dexheimer, Phillip J.; Aronow, Bruce J.; Kottyan, Leah C.; Kaufman, Kenneth M.; Harley, John B.; Huang, Taosheng; Rothenberg, Marc E.
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Unique clinical characteristics, autoantibodies and medication use in Native American patients with systemic lupus erythematosus
err2018-02-27
err21
errOAAI
errKheir, Joseph M.; Guthridge, Carla J.; Johnston, Jonathon R.; Adams, Lucas J.; Rasmussen, Astrid; Gross, Timothy F.; Munroe, Melissa E.; Bourn, Rebecka L.; Sivils, Kathy L.; Guthridge, Joel M.; Weisman, Michael H.; Wallace, Daniel J.; Anaya, Juan-Manuel; Rojas Villarraga, Adriana; Jarvis, James N.; Harley, John B.; James, Judith A.
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Clinical and Serologic Features in Patients With Incomplete Lupus Classification Versus Systemic Lupus Erythematosus Patients and Controls
err2017-11-14
err26
errOAAI
errAberle, Teresa; Bourn, Rebecka L.; Munroe, Melissa E.; Chen, Hua; Roberts, Virginia C.; Guthridge, Joel M.; Bean, Krista; Robertson, Julie M.; Sivils, Kathy L.; Rasmussen, Astrid; Liles, Meghan; Merrill, Joan T.; Harley, John B.; Olsen, Nancy J.; Karp, David R.; James, Judith A.
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Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjogren's Syndrome
err2017-10-12
err36
errOAAI
errSharma, Rohan; Harris, Valerie M.; Cavett, Joshua; Kurien, Biji T.; Liu, Ke; Koelsch, Kristi A.; Fayaaz, Anum; Chaudhari, Kaustubh S.; Radfar, Lida; Lewis, David; Stone, Donald U.; Kaufman, C. Erick; Li, Shibo; Segal, Barbara; Wallace, Daniel J.; Weisman, Michael H.; Venuturupalli, Swamy; Kelly, Jennifer A.; Pons-Estel, Bernardo; Jonsson, Roland; Lu, Xianglan; Gottenberg, Jacques-Eric; Anaya, Juan-Manuel; Cunninghame-Graham, Deborah S.; Huang, Andrew J. W.; Brennan, Michael T.; Hughes, Pamela; Alevizos, Ilias; Miceli-Richard, Corinne; Keystone, Edward C.; Bykerk, Vivian P.; Hirschfield, Gideon; Nordmark, Gunnel; Bucher, Sara Magnusson; Eriksson, Per; Omdal, Roald; Rhodus, Nelson L.; Rischmueller, Maureen; Rohrer, Michael; Wahren-Herlenius, Marie; Witte, Torsten; Alarcon-Riquelme, Marta; Mariette, Xavier; Lessard, Christopher J.; Harley, John B.; Ng, Wan-Fai; Rasmussen, Astrid; Sivils, Kathy L.; Scofield, R. Hal
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Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features利用可溶性介质和临床特征识别系统性红斑狼疮患者亲属的疾病转变风险
err2017-02-27
err49
errOAAI
errMunroe, Melissa E.; Young, Kendra A.; Kamen, Diane L.; Guthridge, Joel M.; Niewold, Timothy B.; Costenbader, Karen H.; Weisman, Michael H.; Ishimori, Mariko L.; Wallace, Daniel J.; Gilkeson, Gary S.; Karp, David R.; Harley, John B.; Norris, Jill M.; James, Judith A.
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Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies
err2016-11-01
err128
errOAAI
errLu, Rufei; Munroe, Melissa E.; Guthridge, Joel M.; Bean, Krista M.; Fife, Dustin A.; Chen, Hua; Slight-Webb, Samantha R.; Keith, Michael P.; Harley, John B.; James, Judith A.
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Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification
err2016-11-01
err209
errOAAI
errMunroe, Melissa E.; Lu, Rufei; Zhao, Yan D.; Fife, Dustin A.; Robertson, Julie M.; Guthridge, Joel M.; Niewold, Timothy B.; Tsokos, George C.; Keith, Michael P.; Harley, John B.; James, Judith A.
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MicroRNA-130b Ameliorates Murine Lupus Nephritis Through Targeting the Type I Interferon Pathway on Renal Mesangial Cells
err2016-08-25
err62
PREAI
errHan, Xiao; Wang, Yan; Zhang, Xiaoyan; Qin, Yuting; Qu, Bo; Wu, Lingling; Ma, Jianyang; Zhou, Zhenyuan; Qian, Jie; Dai, Min; Tang, Yuanjia; Chan, Edward K. L.; Harley, John B.; Zhou, Shiyu; Shen, Nan
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