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收藏分享 收藏 分享 收藏 分享 收藏 MicroRNAs modulate SARS-CoV-2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2
Khanal, Rajendra; Heinen, Natalie; Bogomolova, Alexandra; Meister, Toni L.; Herrmann, Simon T.; Westhoven, Saskia; Nocke, Maximilian K.; Todt, Daniel; Jockenhoevel, Freya; Klein, Isabel M.; Hartmann, Laura; Vondran, Florian W. R.; Steinmann, Eike; Zimmer, Gert; Ott, Michael; Brown, Richard J. P.; Sharma, Amar Deep; Pfaender, Stephanie 分享 收藏 MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinomaOlarewaju, Olaniyi; Hu, Yuhai; Tsay, Hsin-Chieh; Yuan, Qinggong; Eimterbaeumer, Simon; Xie, Yu; Qin, Renyi; Ott, Michael; Sharma, Amar Deep; Balakrishnan, Asha 分享 收藏 A spatiotemporal atlas of mouse liver homeostasis and regeneration小鼠肝脏稳态和再生的时空图谱Xu, Jiangshan; Guo, Pengcheng; Hao, Shijie; Shangguan, Shuncheng; Shi, Quan; Volpe, Giacomo; Huang, Keke; Zuo, Jing; An, Juan; Yuan, Yue; Cheng, Mengnan; Deng, Qiuting; Zhang, Xiao; Lai, Guangyao; Nan, Haitao; Wu, Baihua; Shentu, Xinyi; Wu, Liang; Wei, Xiaoyu; Jiang, Yujia; Huang, Xin; Pan, Fengyu; Song, Yumo; Li, Ronghai; Wang, Zhifeng; Liu, Chuanyu; Liu, Shiping; Li, Yuxiang; Yang, Tao; Xu, Zhicheng; Du, Wensi; Li, Ling; Ahmed, Tanveer; You, Kai; Dai, Zhen; Li, Li; Qin, Baoming; Li, Yinxiong; Lai, Liangxue; Qin, Dajiang; Chen, Junling; Fan, Rong; Li, Yongyin; Hou, Jinlin; Ott, Michael; Sharma, Amar Deep; Cantz, Tobias; Schambach, Axel; Kristiansen, Karsten; Hutchins, Andrew P.; Goettgens, Berthold; Maxwell, Patrick H.; Hui, Lijian; Xu, Xun; Liu, Longqi; Chen, Ao; Lai, Yiwei; Esteban, Miguel A. 分享 收藏 Adeno-associated virus serotype 2 capsid variants for improved liver-directed gene therapyMeumann, Nadja; Cabanes-Creus, Marti; Ertelt, Moritz; Navarro, Renina Gale; Lucifora, Julie; Yuan, Qinggong; Nien-Huber, Karin; Abdelrahman, Ahmed; Vu, Xuan-Khang; Zhang, Liang; Franke, Ann-Christin; Schmithals, Christian; Piiper, Albrecht; Vogt, Annabelle; Gonzalez-Carmona, Maria; Frueh, Jochen T.; Ullrich, Evelyn; Meuleman, Philip; Talbot, Steven R.; Odenthal, Margarete; Ott, Michael; Seifried, Erhard; Schoeder, Clara T.; Schwable, Joachim; Lisowski, Leszek; Buning, Hildegard 分享 收藏 Efficacy and safety of extended duration to perioperative thromboprophylaxis with low molecular weight heparin on disease-free survival after surgical resection of colorectal cancer (PERIOP-01): multicentre, open label, randomised controlled trial低分子肝素延长围手术期血栓预防对结直肠癌手术切除后无病生存的有效性和安全性 (PERIOP-01): 多中心、开放标签、随机对照试验Auer, Rebecca C.; Ott, Michael; Karanicolas, Paul; Brackstone, Muriel Rebecca; Ashamalla, Shady; Weaver, Joel; Tagalakis, Vicky; Boutros, Marylise; Stotland, Peter; Marulanda, Antonio Caycedo; Moloo, Husein; Jayaraman, Shiva; Patel, Suni; Le Gal, Gregoire; Spadafora, Silvana; MacLellan, Steven; Trottier, Daniel; Jonker, Derek; Asmis, Timothy; Mallick, Ranjeeta; Pecarskie, Amanda; Ramsay, Tim; Carrier, Marc 分享 收藏 In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis miceRovai, Alice; Chung, BoMee; Hu, Qingluan; Hook, Sebastian; Yuan, Qinggong; Kempf, Tibor; Schmidt, Florian; Grimm, Dirk; Talbot, Steven R.; Steinbrueck, Lars; Goetting, Jasper; Bohne, Jens; Krooss, Simon A.; Ott, Michael 分享 收藏 Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical modelYang, Taihua; Poenisch, Marion; Khanal, Rajendra; Hu, Qingluan; Dai, Zhen; Li, Ruomeng; Song, Guangqi; Yuan, Qinggong; Yao, Qunyan; Shen, Xizhong; Taubert, Richard; Engel, Bastian; Jaeckel, Elmar; Vogel, Arndt; Falk, Christine S.; Schambach, Axel; Gerovska, Daniela; Arauzo-Bravo, Marcos J.; Vondran, Florian W. R.; Cantz, Tobias; Horscroft, Nigel; Balakrishnan, Asha; Chevessier, Frederic; Ott, Michael; Sharma, Amar Deep 分享 收藏 Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration体细胞重编程过程中的功能基因组筛选将DKK3鉴定为器官再生的路障Arnold, Frank; Mahaddalkar, Pallavi U.; Kraus, Johann M.; Zhong, Xiaowei; Bergmann, Wendy; Srinivasan, Dharini; Gout, Johann; Roger, Elodie; Beutel, Alica K.; Zizer, Eugen; Tharehalli, Umesh; Daiss, Nora; Russell, Ronan; Perkhofer, Lukas; Oellinger, Rupert; Lin, Qiong; Azoitei, Ninel; Weiss, Frank-Ulrich; Lerch, Markus M.; Liebau, Stefan; Katz, Sarah-Fee; Lechel, Andre; Rad, Roland; Seufferlein, Thomas; Kestler, Hans A.; Ott, Michael; Sharma, Amar Deep; Hermann, Patrick C.; Kleger, Alexander 分享 收藏 MicroRNA-342-3p is a potent tumour suppressor in hepatocellular carcinomaMicroRNA-342-3p是肝细胞癌的有效肿瘤抑制剂Komoll, Ronja-Melinda; Hu, Qingluan; Olarewaju, Olaniyi; von Doehlen, Lena; Yuan, Qinggong; Xie, Yu; Tsay, Hsin-Chieh; Daon, Joel; Qin, Renyi; Manns, Michael P.; Sharma, Amar Deep; Goga, Andrei; Ott, Michael; Balakrishnan, Asha 分享 收藏 Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to miceBrown, Richard J. P.; Tegtmeyer, Birthe; Sheldon, Julie; Khera, Tanvi; Anggakusuma; Todt, Daniel; Vieyres, Gabrielle; Weller, Romy; Joecks, Sebastian; Zhang, Yudi; Sake, Svenja; Bankwitz, Dorothea; Welsch, Kathrin; Ginkel, Corinne; Engelmann, Michael; Gerold, Gisa; Steinmann, Eike; Yuan, Qinggong; Ott, Michael; Vondran, Florian W. R.; Krey, Thomas; Stroeh, Luisa J.; Miskey, Csaba; Ivics, Zoltan; Herder, Vanessa; Baumgaertner, Wolfgang; Lauber, Chris; Seifert, Michael; Tarr, Alexander W.; McClure, C. Patrick; Randall, Glenn; Baktash, Yasmine; Ploss, Alexander; Thi, Viet Loan Dao; Michailidis, Eleftherios; Saeed, Mohsan; Verhoye, Lieven; Meuleman, Philip; Goedecke, Natascha; Wirth, Dagmar; Rice, Charles M.; Pietschmann, Thomas 分享 收藏 microRNA-93-5p promotes hepatocellular carcinoma progression via a microRNA-93-5p/MAP3K2/c-Jun positive feedback circuitShi, Xuan; Liu, Tao-Tao; Yu, Xiang-Nan; Balakrishnan, Asha; Zhu, Hai-Rong; Guo, Hong-Ying; Zhang, Guang-Cong; Bilegsaikhan, Enkhnaran; Sun, Jia-Lei; Song, Guang-Qi; Weng, Shu-Qiang; Dong, Ling; Ott, Michael; Zhu, Ji-Min; Shen, Xi-Zhong 分享 收藏 Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia BKrooss, Simon; Werwitzke, Sonja; Kopp, Johannes; Rovai, Alice; Varnholt, Dirk; Wachs, Amelie S.; Goyenvalle, Aurelie; Aarstma-Rus, Annemieke; Ott, Michael; Tiede, Andreas; Langemeier, Joerg; Bohne, Jens 分享 收藏 分享 收藏 Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosisTsay, Hsin-Chieh; Yuan, Qinggong; Balakrishnan, Asha; Kaiser, Marina; Moebus, Selina; Kozdrowska, Emilia; Farid, Marwa; Tegtmeyer, Pia-Katharina; Borst, Katharina; Vondran, Florian W. R.; Kalinke, Ulrich; Kispert, Andreas; Manns, Michael P.; Ott, Michael; Sharma, Amar Deep 分享 收藏 Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected miceKoestner, Wolfgang; Spanier, Julia; Klause, Tanja; Tegtmeyer, Pia-K.; Becker, Jennifer; Herder, Vanessa; Borst, Katharina; Todt, Daniel; Lienenklaus, Stefan; Gerhauser, Ingo; Detje, Claudia N.; Geffers, Robert; Langereis, Martijn A.; Vondran, Florian W. R.; Yuan, Qinggong; van Kuppeveld, Frank J. M.; Ott, Michael; Staeheli, Peter; Steinmann, Eike; Baumgaertner, Wolfgang; Wacker, Frank; Kalinke, Ulrich 分享 收藏 Expansion of functional personalized cells with specific transgene combinationsLipps, Christoph; Klein, Franziska; Wahlicht, Tom; Seiffert, Virginia; Butueva, Milada; Zauers, Jeannette; Truschel, Theresa; Luckner, Martin; Koester, Mario; MacLeod, Roderick; Pezoldt, Joern; Huehn, Jochen; Yuan, Qinggong; Mueller, Peter Paul; Kempf, Henning; Zweigerdt, Robert; Dittrich-Breiholz, Oliver; Pufe, Thomas; Beckmann, Rainer; Drescher, Wolf; Riancho, Jose; Sanudo, Carolina; Korff, Thomas; Opalka, Bertram; Rebmann, Vera; Goethert, Joachim R.; Alves, Paula M.; Ott, Michael; Schucht, Roland; Hauser, Hansjoerg; Wirth, Dagmar; May, Tobias 分享 收藏 
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