Jack L. Leahy - Publications, H-index & Citations

Islet amyloid and type 2 diabetes: overproduction or inadequate clearance and detoxification?

IF3.9

2017-07-01

OAAI

Gupta, Dhananjay; Jetton, Thomas L.; LaRock, Kyla; Monga, Navjot; Satish, Basanthi; Lausier, James; Peshavaria, Mina; Leahy, Jack L.

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2014-07-18

OAAI

Gupta, Dhananjay; Leahy, Jack L.

Peroxisome Proliferator-activated Receptor γ(PPARγ) and Its Target Genes Are Downstream Effectors of FoxO1 Protein in Islet β-Cells

An analysis of early insulin glargine added to metformin with or without sulfonylurea: impact on glycaemic control and hypoglycaemia

IF3.9

2013-08-01

OAAI

Gupta, Dhananjay; Leahy, Averi A.; Monga, Navjot; Peshavaria, Mina; Jetton, Thomas L.; Leahy, Jack L.

DIABETES OBESITY & METABOLISM

IF5.7

2011-07-26

OAAI

Fonseca, V.; Gill, J.; Zhou, R.; Leahy, J.

Targeting β-Cell Function Early in the Course of Therapy for Type 2 Diabetes Mellitus

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2010-09-01

105

OAAI

Leahy, Jack L.; Hirsch, Irl B.; Peterson, Kevin A.; Schneider, Doron

Physiologic and Pharmacologic Modulation of Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Expression in β-Cells by Peroxisome Proliferator-Activated Receptor (PPAR)-γ Signaling Possible Mechanism for the GIP Resistance in Type 2 Diabetes

Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass

IF7.5

2010-03-23

OAAI

Gupta, Dhananjay; Peshavaria, Mina; Monga, Navjot; Jetton, Thomas L.; Leahy, Jack L.

In Vivo and in Vitro Studies of a Functional Peroxisome Proliferator-activated Receptor γ Response Element in the Mouse pdx-1 Promoter

IF10.2

2009-03-18

OAAI

Delghingaro-Augusto, V.; Nolan, C. J.; Gupta, D.; Jetton, T. L.; Latour, M. G.; Peshavaria, M.; Madiraju, S. R. Murthy; Joly, E.; Peyot, M. -L.; Prentki, M.; Leahy, J.

Peroxisonte proliferator-activated receptor-γ regulates expression of PDX-1 and NKX6.1 in INS-1 cells

IF3.9

2008-11-01

OAAI

Gupta, Dhananjay; Jetton, Thomas L.; Mortensen, Richard M.; Duan, Sheng Zhong; Peshavaria, Mina; Leahy, Jack L.

Regulation of pancreatic β-cell regeneration in the normoglycemic 60% partial-pancreatectomy mouse

IF7.5

2007-01-01

OAAI

Moibi, Jacob A.; Gupta, Dhananjay; Jetton, Thomas L.; Peshavaria, Mina; Desai, Ronak; Leahy, Jack L.

Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling Zucker肥胖大鼠胰岛素抵抗的 β 细胞补偿: 脂解和脂肪酸信号传导增加

IF7.5

2006-12-01

132

OAAI

Peshavaria, Mina; Larmie, Brooke L.; Lausier, James; Satish, Basanthi; Habibovic, Aida; Roskens, Violet; LaRock, Kyla; Everill, Brian; Leahy, Jack L.; Jetton, Thomas L.

Mechanisms of compensatory β-cell growth in insulin-resistant rats -: Roles of Akt kinase

IF10.2

2006-07-26

129

OAAI

Nolan, C. J.; Leahy, J. L.; Delghingaro-Augusto, V.; Moibi, J.; Soni, K.; Peyot, M. -L.; Fortier, M.; Guay, C.; Lamontagne, J.; Barbeau, A.; Przybytkowski, E.; Joly, E.; Masiello, P.; Wang, S.; Mitchell, G. A.; Prentki, M.

β-cell adaptation to insulin resistance -: Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic Zucker fatty rats

IF7.5

2005-08-01

166

OAAI

Jetton, TL; Lausier, J; LaRock, K; Trotman, WE; Larmie, B; Habibovic, A; Peshavaria, M; Leahy, JL

Characterization of a novel metabolic strategy used by drug-resistant tumor cells

IF3.9

2002-10-01

154

OAAI

Liu, YQ; Jetton, TL; Leahy, JL

FASEB JOURNAL

IF4.2

2002-10-01

167

PREAI

Harper, ME; Antoniou, A; Villalobos-Menuey, E; Russo, A; Trauger, R; Vendemelio, M; George, A; Bartholomew, R; Carlo, D; Shaikh, A; Kupperman, J; Newell, EW; Bespalov, IA; Wallace, SS; Liu, Y; Rogers, JR; Gibbs, GL; Leahy, JL; Camley, RE; Melamede, R; Newell, MK

Increased islet DNA synthesis and glucose-derived lipid and amino acid production in association with beta-cell hyperproliferation in normoglycaemic 60 % pancreatectomy rats 血糖正常的60% 胰腺切除术大鼠胰岛DNA合成增加以及葡萄糖衍生的脂质和氨基酸产生与 β 细胞过度增殖有关

How is the insulin content regulated in nondiabetic hyperinsulinaemic, insulin resistant states? Study of spontaneously hypertensive rats

IF10.2

2001-08-01

OAAI

Lin, YQ; Montanya, E; Leahy, JL