William C. Merrick - Publications, H-index & Citations

William C. Merrick

University System of Ohio

78H指数

284论文数

2.0W被引数

收录论文 62

发表时间

Plasticity of the mammalian integrated stress response 哺乳动物整合应激反应的塑性

NATURE

IF48.5

2025-03-26

OAAI

Chen, Chien-Wen; Papadopoli, David; Szkop, Krzysztof J.; Guan, Bo-Jhih; Alzahrani, Mohammed; Wu, Jing; Jobava, Raul; Asraf, Mais M.; Krokowski, Dawid; Vourekas, Anastasios; Merrick, William C.; Komar, Anton A.; Koromilas, Antonis E.; Gorospe, Myriam; Payea, Matthew J.; Wang, Fangfang; Clayton, Benjamin L. L.; Tesar, Paul J.; Schaffer, Ashleigh; Miron, Alexander; Bederman, Ilya; Jankowsky, Eckhard; Vogel, Christine; Valasek, Leos Shivaya; Dinman, Jonathan D.; Zhang, Youwei; Tirosh, Boaz; Larsson, Ola; Topisirovic, Ivan; Hatzoglou, Maria

The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

515

OAAI

Yang, HS; Jansen, AP; Komar, AA; Zheng, XJ; Merrick, WC; Costes, S; Lockett, SJ; Sonenberg, N; Colburn, NH

Efficient translation initiation directed by the 900-nucleotide-long and GC-rich 5′ untranslated region of the human retrotransposon LINE-1 mRNA is strictly cap dependent rather than internal ribosome entry site mediated

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

124

OAAI

Dmitriev, Sergey E.; Andreev, Dmitri E.; Terenin, Ilya M.; Olovnikov, Ivan A.; Prassolov, Vladimir S.; Merrick, William C.; Shatsky, Ivan N.

Assembly of 48S translation initiation complexes from purified components with mRNAs that have some base pairing within their 5′ untranslated regions

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Dmitriev, SE; Terenin, IM; Dunaevsky, YE; Merrick, WC; Shatsky, IN

Human eukaryotic initiation factor 4E (eIF4E) and the nucleotide-bound state of eIF4A regulate eIF4F binding to RNA

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-10-01

OAAI

Izidoro, Mario Servulo; Sokabe, Masaaki; Villa, Nancy; Merrick, William C.; Fraser, Christopher S.

Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR

CELL REPORTS

IF6.9

2022-07-01

OAAI

Krokowski, Dawid; Jobava, Raul; Szkop, Krzysztof J.; Chen, Chien-Wen; Fu, Xu; Venus, Sarah; Guan, Bo-Jhih; Wu, Jing; Gao, Zhaofeng; Banaszuk, Wioleta; Tchorzewski, Marek; Mu, Tingwei; Ropelewski, Phil; Merrick, William C.; Mao, Yuanhui; Sevval, Aksoylu Inci; Miranda, Helen; Qian, Shu-Bing; Manifava, Maria; Ktistakis, Nicholas T.; Vourekas, Anastasios; Jankowsky, Eckhard; Topisirovic, Ivan; Larsson, Ola; Hatzoglou, Maria

eIF2A-knockout mice reveal decreased life span and metabolic syndrome eIF2A-knockout小鼠显示寿命缩短和代谢综合征

FASEB JOURNAL

IF4.2

2021-10-19

OAAI

Anderson, Richard; Agarwal, Anchal; Ghosh, Arnab; Guan, Bo-Jhih; Casteel, Jackson; Dvorina, Nina; Baldwin, William M.; Mazumder, Barsanjit; Nazarko, Taras Y.; Merrick, William C.; Buchner, David A.; Hatzoglou, Maria; Kondratov, Roman, V; Komar, Anton A.

Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress

MOLECULAR CELL

IF16.6

2021-10-01

OAAI

Jobava, Raul; Mao, Yuanhui; Guan, Bo-Jhih; Hu, Di; Krokowski, Dawid; Chen, Chien-Wen; Shu, Xin Erica; Chukwurah, Evelyn; Wu, Jing; Gao, Zhaofeng; Zagore, Leah L.; Merrick, William C.; Trifunovic, Aleksandra; Hsieh, Andrew C.; Valadkhan, Saba; Zhang, Youwei; Qi, Xin; Jankowsky, Eckhard; Topisirovic, Ivan; Licatalosi, Donny D.; Qian, Shu-Bing; Hatzoglou, Maria

eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function

NUCLEIC ACIDS RESEARCH

IF13.1

2020-05-06

OAAI

Lyons, Shawn M.; Kharel, Prakash; Akiyama, Yasutoshi; Ojha, Sandeep; Dave, Dhwani; Tsvetkov, Vladimir; Merrick, William; Ivanov, Pavel; Anderson, Paul

Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F

CELL REPORTS

IF6.9

2020-02-01

OAAI

Chu, Jennifer; Zhang, Wenhan; Cencic, Regina; O'Connor, Patrick B. F.; Robert, Francis; Devine, William G.; Selznick, Asher; Henkel, Thomas; Merrick, William C.; Brown, Lauren E.; Baranov, Pavel V.; Porco, John A., Jr.; Pelletier, Jerry

Protein Synthesis Initiation in Eukaryotic Cells

cold spring harbor perspectives in medicine

IF8.4

2018-05-07

257

OAAI

Merrick, William C.; Pavitt, Graham D.

A Unique ISR Program Determines Cellular Responses to Chronic Stress

MOLECULAR CELL

IF16.6

2017-12-01

137

OAAI

Guan, Bo-Jhih; van Hoef, Vincent; Jobava, Raul; Elroy-Stein, Orna; Valasek, Leos S.; Cargnello, Marie; Gao, Xing-Huang; Krokowski, Dawid; Merrick, William C.; Kimball, Scot R.; Komar, Anton A.; Koromilas, Antonis E.; Wynshaw-Boris, Anthony; Topisirovic, Ivan; Larsson, Ola; Hatzoglou, Maria

The eIF2A knockout mouse

CELL CYCLE

IF3.4

2016-11-01

OAAI

Golovko, Andrei; Kojukhov, Artyom; Guan, Bo-Jhih; Morpurgo, Benjamin; Merrick, William C.; Mazumder, Barsanjit; Hatzoglou, Maria; Komar, Anton A.

Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex

ELIFE

IF0

2015-12-10

OAAI

Carelli, Jordan D.; Sethofer, Steven G.; Smith, Geoffrey A.; Miller, Howard R.; Simard, Jillian L.; Merrick, William C.; Jain, Rishi K.; Ross, Nathan T.; Taunton, Jack

OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation OLA1通过抑制eIF2三元复合物形成调节蛋白质合成和综合应激反应

SCIENTIFIC REPORTS

IF3.9

2015-08-18

OAAI

Chen, Huarong; Song, Renduo; Wang, Guohui; Ding, Zonghui; Yang, Chunying; Zhang, Jiawei; Zeng, Zihua; Rubio, Valentina; Wang, Luchang; Zu, Nancy; Weiskoff, Amanda M.; Minze, Laurie J.; Jeyabal, Prince V. S.; Mansour, Oula C.; Bai, Li; Merrick, William C.; Zheng, Shu; Shi, Zheng-Zheng

Characterization of hibernating ribosomes in mammalian cells

CELL CYCLE

IF3.4

2014-10-28

OAAI

Krokowski, Dawid; Gaccioli, Francesca; Majumder, Mithu; Mullins, Michael R.; Yuan, Celvie L.; Papadopoulou, Barbara; Merrick, William C.; Komar, Anton A.; Taylor, Derek; Hatzoglou, Maria

Translational Control during Endoplasmic Reticulum Stress beyond Phosphorylation of the Translation Initiation Factor eIF2α

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-05-01

151

OAAI

Guan, Bo-Jhih; Krokowski, Dawid; Majumder, Mithu; Schmotzer, Christine L.; Kimball, Scot R.; Merrick, William C.; Koromilas, Antonis E.; Hatzoglou, Maria

Rapid kinetics of iron responsive element (IRE) RNA/iron regulatory protein 1 and IRE-RNA/eIF4F complexes respond differently to metal ions

NUCLEIC ACIDS RESEARCH

IF13.1

2014-04-11

OAAI

Khan, Mateen A.; Ma, Jia; Walden, William E.; Merrick, William C.; Theil, Elizabeth C.; Goss, Dixie J.

Control not at initiation? Bah, humbug!

EMBO JOURNAL

IF8.3

2013-12-22

OAAI

Merrick, William C.; Harris, Michael E.

Chimeric Glutathione S-Transferases Containing Inserts of Kininogen Peptides POTENTIAL NOVEL PROTEIN THERAPEUTICS

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-06-01

OAAI

Bentley, Amber A.; Merkulov, Sergei M.; Peng, Yi; Rozmarynowycz, Rita; Qi, Xiaoping; Pusztai-Carey, Marianne; Merrick, William C.; Yee, Vivien C.; McCrae, Keith R.; Komar, Anton A.

研究方向