Ratna K. Vadlamudi - Publications, H-index & Citations

Ratna K. Vadlamudi

university of texas health science center at san antonio

70H指数

616论文数

1.5W被引数

收录论文 55

发表时间

Therapeutic optimization of LIPA targeting to induce endoplasmic reticulum stress and cell death in ovarian cancer LIPA靶向诱导卵巢癌内质网应激和细胞死亡的治疗优化

Oncogene

IF7.3

2026-02-06

OAAI

Suryavathi Viswanadhapalli; Tae-Kyung Lee; Scott Elmore; Gaurav Sharma; Rahul Gopalam; Durga Meenakshi Panneerdoss; Xihui Liu; Karla Parra; Tanner Reese; Michael Hsieh; Uday P. Pratap; Xue Yang; Behnam Ebrahimi; Xiaonan Li; Henry Neal; Chia-Yuan Chen; Kara Kassees; Christian Cervantes; Adriana Baker; Panneerdoss Subbarayalu; Paulina Ramirez; Yasmin A. Lyons; Zhao Lai; Yidong Chen; Joseph W. Boerma; Peter M. LoCoco; Nicholas A. Clanton; Zhenming Xu; Manjeet Rao; Tekmal Rajeshwar Rao; Edward Kost; Gangadhara R. Sareddy; Ganesh V. Raj; Jung-Mo Ahn; Ratna K. Vadlamudi

Midkine (MDK) as a Central Regulator of the Tumor Microenvironment: From Developmental Cytokine to Therapeutic Target

Cancer Letters

IF10.1

2026-01-20

OAAI

Hareesh B. Nair; Ajay Nair; Ya-Guang Liu; Dileep K. Vijayan; Ramadevi Subramani; Rajkumar Lakshmanaswamy; Suryavathi Viswanadhapalli; Gangadhara Sareddy; Surinder K. Batra; Ratna K. Vadlamudi

Dual Targeting of KDM1A/LSD1 and Endoplasmic Reticulum Stress Pathways as a Therapeutic Strategy in Glioblastoma KDM1A/LSD1和内质网应激通路的双靶向作为胶质母细胞瘤的治疗策略

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

He, Yi; Jayamohan, Sridharan; Alejo, Salvador; Johnson, Jessica; Venkata, Prabhakar; Chen, Yidong; Lai, Zhao; Zheng, Siyuan; Vadlamudi, Ratna; Brenner, Andrew; Sareddy, Gangadhara

Ligand-receptor interactions induce and mediate regulatory functions of BATF3+ B cells 配体-受体相互作用诱导并介导BATF3+ B细胞的调控功能

Science Advances

IF12.5

2025-10-08

PREAI

Hui Yan; Rui Wang; Suryavathi Viswanadhapalli; Christian Cervantes; Funan He; Shuai Wu; Azad Khosh; Weiwei Luo; Jingwei Wang; Maria J. Fernandez; Uday P. Pratap; Mustafa Khan; Karli Hinton; Sai Eashan Vankamamidi; Dariela Perez; Carlos E. Rivera; Harshita B. Gupta; Fushun Zhang; Zhenqing Ye; Yidong Chen; Xiao-Dong Li; Gangadhara R. Sareddy; Hong Zan; Yue Li; Exing Wang; Evelien M. Bunnik; Guangming Zhong; Christopher A. Hunter; Ross M. Kedl; Zhinan Yin; Booki Min; Diako Ebrahimi; Siyuan Zheng; Tyler J. Curiel; Yan Xiang; Ratna K. Vadlamudi; Paolo Casali; Zhenming Xu

EC359 Enhances Trametinib Efficacy in Ras/Raf-Driven Ovarian Cancer by Suppressing LIFR Signaling EC359 通过抑制 LIFR 信号通路增强 Trametinib 在 Ras/Raf 驱动的卵巢癌中的疗效

Biomolecules 2025, Vol. 15, Page 1396

IF4.8

2025-10-01

OAAI

William C. Arnold; Durga Meenakshi Panneerdoss; Baskaran Subramani; Megharani Mahajan; Behnam Ebrahimi; Paulina Ramirez; Bindu Santhamma; Suryavathi Viswanadhapalli; Edward R. Kost; Yidong Chen; Zhao Lai; Hareesh B. Nair; Ratna K. Vadlamudi; Yasmin A. Lyons

Cryo-EM structures reveal the molecular mechanism of SUMO E1–E2 thioester transfer 冷冻电镜结构揭示了SUMO E1–E2硫酯转移的分子机制

Nature Structural & Molecular Biology

IF10.1

2025-09-25

OAAI

Anindita Nayak; Digant Nayak; Lijia Jia; Eliza A. Ruben; Suryavathi Viswanadhapalli; Priscila dos Santos Bury; Khaled Mohamed Nassar; Corey H. Yu; Anna A. Tumanova; Caleb M. Stratton; Pirouz Ebadi; Dmitri N. Ivanov; Patrick Sung; Ratna K. Vadlamudi; Elizabeth V. Wasmuth; Shaun K. Olsen

Significance of Midkine Signaling in Women's Cancers: Novel Biomarker and Therapeutic Target Midkine信号在女性癌症中的意义：新型生物标志物和治疗靶点

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-05-17

OAAI

Aller, Emily J.; Nair, Hareesh B.; Vadlamudi, Ratna K.; Viswanadhapalli, Suryavathi

Epigenetic silencing of DNA sensing pathway by FOXM1 blocks stress ligand-dependent antitumor immunity and immune memory FOXM1介导的表观遗传沉默DNA传感通路会阻断压力配体依赖性的抗肿瘤免疫和免疫记忆

NATURE COMMUNICATIONS

IF15.7

2025-04-28

OAAI

Timilsina, Santosh; Huang, Jian Yu; Abdelfattah, Nourhan; Medina, Daisy; Singh, Deepika; Abdulsahib, Shahad; Subbarayalu, Panneerdoss; Do, Trong Phat; Venkata, Prabhakar Pitta; Nirzhor, Saif; Prochnau, Jack; Bhandari, Mukund; Zheng, Siyuan; Chen, Yidong; Huang, Gang; Mukherjee, Neelam; Hromas, Robert; Sung, Patrick; Kaklamani, Virginia; Vadlamudi, Ratna; Zhang, Nu; Rao, Manjeet K.

Tumour-intrinsic PDL1 signals regulate the Chk2 DNA damage response in cancer cells and mediate resistance to Chk1 inhibitors 肿瘤内在的PDL1信号调节癌细胞中Chk2 DNA损伤反应并介导对Chk1抑制剂的抗性

MOLECULAR CANCER

IF33.9

2024-10-30

PREAI

Murray, Clare E.; Kornepati, Anand V. R.; Ontiveros, Carlos; Liao, Yiji; de la Pena Avalos, Barbara; Rogers, Cody M.; Liu, Zexuan; Deng, Yilun; Bai, Haiyan; Kari, Suresh; Padron, Alvaro S.; Boyd, Jacob T.; Reyes, Ryan; Clark, Curtis A.; Svatek, Robert S.; Li, Rong; Hu, Yanfen; Wang, Meiling; Conejo-Garcia, Jose R.; Byers, Lauren A.; Ramkumar, Kavya; Sood, Anil K.; Lee, Jung-Min; Burd, Christin E.; Vadlamudi, Ratna K.; Gupta, Harshita B.; Zhao, Weixing; Dray, Eloise; Sung, Patrick; Curiel, Tyler J.

KDM1A/LSD1 inhibition enhances chemotherapy response in ovarian cancer KDM1A/LSD1抑制增强卵巢癌的化疗反应

MOLECULAR CARCINOGENESIS

IF3.2

2024-07-11

PREAI

Chen, Yihong; Johnson, Jessica D.; Jayamohan, Sridharan; He, Yi; Venkata, Prabhakar P.; Jamwal, Diksha; Alejo, Salvador; Zou, Yi; Lai, Zhao; Viswanadhapalli, Suryavathi; Vadlamudi, Ratna K.; Kost, Edward; Sareddy, Gangadhara R.

Pharmacological inhibition of the LIF/LIFR autocrine loop reveals vulnerability of ovarian cancer cells to ferroptosis

NPJ PRECISION ONCOLOGY

IF8

2024-05-24

OAAI

Ebrahimi, Behnam; Viswanadhapalli, Suryavathi; Pratap, Uday P.; Rahul, Gopalam; Yang, Xue; Pitta Venkata, Prabhakar; Drel, Viktor; Santhamma, Bindu; Konda, Swapna; Li, Xiaonan; Sanchez, Alondra Lee Rodriguez; Yan, Hui; Sareddy, Gangadhara R.; Xu, Zhenming; Singh, Brij B.; Valente, Philip T.; Chen, Yidong; Lai, Zhao; Rao, Manjeet; Kost, Edward R.; Curiel, Tyler; Tekmal, Rajeshwar R.; Nair, Hareesh B.; Vadlamudi, Ratna K.

Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress (vol 3, pg 866, 2022)

NATURE CANCER

IF28.5

2024-05-20

OAAI

Liu, Xihui; Viswanadhapalli, Suryavathi; Kumar, Shourya; Lee, Tae-Kyung; Moore, Andrew; Ma, Shihong; Chen, Liping; Hsieh, Michael; Li, Mengxing; Sareddy, Gangadhara R.; Parra, Karla; Blatt, Eliot B.; Reese, Tanner C.; Zhao, Yuting; Chang, Annabel; Yan, Hui; Xu, Zhenming; Pratap, Uday P.; Liu, Zexuan; Roggero, Carlos M.; Tan, Zhenqiu; Weintraub, Susan T.; Peng, Yan; Tekmal, Rajeshwar R.; Arteaga, Carlos L.; Lippincott-Schwartz, Jennifer; Vadlamudi, Ratna K.; Ahn, Jung-Mo; Raj, Ganesh V.

A cyclin D1 intrinsically disordered domain accesses modified histone motifs to govern gene transcription

ONCOGENESIS

IF6.4

2024-01-08

OAAI

Jiao, Xuanmao; Di Sante, Gabriele; Casimiro, Mathew C.; Tantos, Agnes; Ashton, Anthony W.; Li, Zhiping; Quach, Yen; Bhargava, Dharmendra; Di Rocco, Agnese; Pupo, Claudia; Crosariol, Marco; Lazar, Tamas; Tompa, Peter; Wang, Chenguang; Yu, Zuoren; Zhang, Zhao; Aldaaysi, Kawthar; Vadlamudi, Ratna; Mann, Monica; Skordalakes, Emmanuel; Kossenkov, Andrew; Du, Yanming; Pestell, Richard G.

PELP1 inhibition by SMIP34 reduces endometrial cancer progression via attenuation of ribosomal biogenesis

MOLECULAR ONCOLOGY

IF4.5

2023-11-01

OAAI

Yang, Xue; Liu, Zexuan; Tang, Weiwei; Pratap, Uday P.; Collier, Alexia B.; Altwegg, Kristin A.; Gopalam, Rahul; Li, Xiaonan; Yuan, Yaxia; Zhou, Daohong; Lai, Zhao; Chen, Yidong; Sareddy, Gangadhara R.; Valente, Philip T.; Kost, Edward R.; Viswanadhapalli, Suryavathi; Vadlamudi, Ratna K.

Pharmacological inhibition of KDM1A/LSD1 enhances estrogen receptor beta-mediated tumor suppression in ovarian cancer

CANCER LETTERS

IF10.1

2023-10-01

OAAI

Venkata, Prabhakar Pitta; Jayamohan, Sridharan; He, Yi; Alejo, Salvador; Johnson, Jessica D.; Palacios, Bridgitte E.; Pratap, Uday P.; Chen, Yihong; Liu, Zexuan; Zou, Yi; Lai, Zhao; Suzuki, Takayoshi; Viswanadhapalli, Suryavathi; Weintraub, Susan T.; Palakurthi, Srinath; Valente, Philip T.; Tekmal, Rajeshwar R.; Kost, Edward R.; Vadlamudi, Ratna K.; Sareddy, Gangadhara R.

Preclinical Development of Brain Permeable ERβ Agonist for the Treatment of Glioblastoma

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-07-25

OAAI

Pratap, Uday P.; Tidwell, Michael; Balinda, Henriette U.; Clanton, Nicholas A.; Yang, Xue; Viswanadhapalli, Suryavathi; Sareddy, Gangadhara R.; Liang, Dong; Xie, Huan; Chen, Yidong; Lai, Zhao; Tekmal, Rajeshwar R.; Mchardy, Stanton F.; Brenner, Andrew J.; Vadlamudi, Ratna K.

Targeting PELP1 oncogenic signaling in TNBC with the small molecule inhibitor SMIP34 用小分子抑制剂SMIP34靶向TNBC中的PELP1致癌信号传导

BREAST CANCER RESEARCH AND TREATMENT

IF3

2023-05-18

OAAI

Altwegg, Kristin A.; Pratap, Uday P.; Liu, Zexuan; Liu, Junhao; Sanchez, John R.; Yang, Xue; Ebrahimi, Behnam; Panneerdoss, Durga Meenakshi; Li, Xiaonan; Sareddy, Gangadhara R.; Viswanadhapalli, Suryavathi; Rao, Manjeet K.; Vadlamudi, Ratna K.

The RNA Demethylase ALKBH5 Maintains Endoplasmic Reticulum Homeostasis by Regulating UPR, Autophagy, and Mitochondrial Function

CELLS

IF5.2

2023-04-29

OAAI

Subbarayalu, Panneerdoss; Yadav, Pooja; Timilsina, Santosh; Medina, Daisy; Baxi, Kunal; Hromas, Robert; Vadlamudi, Ratna K.; Chen, Yidong; Sung, Patrick; Rao, Manjeet K.

KDM1A/LSD1 inhibition enhances estrogen receptor beta mediated tumor suppression in ovarian cancer

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Venkata, Prabhakar P.; Jayamohan, Sridharan; He, Yi; Alejo, Salvador; Johnson, Jessica D.; Pratap, Uday P.; Viswanadhapalli, Suryavathi; Weintraub, Susan; Tekmal, Rajeshwar R.; Vadlamudi, Ratna K.; Kost, Edward; Sareddy, Gangadhara R.

Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma

NEURO-ONCOLOGY

IF13.4

2023-01-18

OAAI

Alejo, Salvador; Palacios, Bridgitte E.; Venkata, Prabhakar Pitta; He, Yi; Li, Wenjing; Johnson, Jessica D.; Chen, Yihong; Jayamohan, Sridharan; Pratap, Uday P.; Clarke, Kyra; Zou, Yi; Lv, Yingli; Weldon, Korri; Viswanadhapalli, Suryavathi; Lai, Zhao; Ye, Zhenqing; Chen, Yidong; Gilbert, Andrea R.; Suzuki, Takayoshi; Tekmal, Rajeshwar R.; Zhao, Weixing; Zheng, Siyuan; Vadlamudi, Ratna K.; Brenner, Andrew J.; Sareddy, Gangadhara R.

研究方向