未登录 Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function 将TCR复合物募集到T细胞抗原偶联物 (TAC) 可增强tac-t细胞功能 Morey, Trevor M.; Benatar, Tania; Xu, Stacey X.; Wang, Ling; Ip, Philbert; Nitya-Nootan, Thanyashanthi; Thakor, Gargi; Bader, Andreas G.; Helsen, Christopher W.; Houry, Walid A. 分享 收藏
分享 收藏
T-cell engineered with a fully humanized B-cell maturation antigen- specific T-cell antigen coupler receptor effectively target multiple myeloma 用完全人源化的b细胞成熟抗原特异性T细胞抗原偶联受体工程化的T细胞有效靶向多发性骨髓瘤 Bezverbnaya, Ksenia; Hammill, Joanne A.; Cummings, Derek; Bojovic, Bojana; Groisman, Bella; Baker, Christopher L.; Aarts, Craig; Hayes, Danielle L.; Rill, Donna; Xu, Stacey X.; Bader, Andreas G.; Helsen, Christopher W.; Bramson, Jonathan L. 分享 收藏
Patient-derived TAC01-HER2 TAC T cells produced in Cocoon® Platform is highly functional in models of solid tumors Wang, Ling; Xu, Stacey X.; Benatar, Tania; Randhawa, Ritu R.; Ip, Philbert; Lal, Prabha; Nitya-Nootan, Thanyashanthi; Ravensbergen, Laura; MacGregor, Heather; Prosser, Suzy; Sengupta, Sadhak; Helsen, Christopher W.; Bader, Andreas G. 分享 收藏
Preclinical characterization of allogeneic V.9Vd2 HER2-TAC T cells for the treatment of HER2-positive solid tumors Prosser, Suzanna L.; Xu, Stacey X.; Wang, Ling; Randhawa, Ritu R.; Pirati, Sailaja; Ravensbergen, Laura; Yoo, Seungmi; Jung, Miyoung; Gheorghiu, Laurentia; Gomez, Angel; Sandhu, Gurleen; Ayers, Chris; Rill, Donna; Helsen, Christopher W.; Bader, Andreas G. 分享 收藏
分享 收藏
DEVELOPMENT OF GUCY2C-TAC T CELLS FOR THE TREATMENT OF COLORECTAL CANCER Benatar, Tania; Wang, Ling; Nitya-Nootan, Thanyashanthi; MacGregor, Heather; Prosser, Suzanna; Philbert, I. P.; Lal, Prabha; Xu, Stacey; Shaver, Laura; Sengupta, Sadhak; Helsen, Christopher; Bader, Andreas 分享 收藏
PRECLINICAL STUDIES OF TAC01-CLDN18.2, AN AUTOLOGOUS CLAUDIN 18.2-DIRECTED TAC T CELL THERAPY, IN THE TREATMENT OF GASTRIC CANCER Wang, Ling; Xu, Stacey; Benatar, Tania; Prosser, Suzanna; Shaver, Laura; Randhawa, Ritu; Ip, Philbert; Lal, Prabha; Nitya-Nootan, Thanyashanthi; MacGregor, Heather; Sengupta, Sadhak; Helsen, Christopher; Bader, Andreas 分享 收藏
EVIDENCE FOR DURABLE ANTI-TUMOR RESPONSES BY TAC-T CELLS IN PRECLINICAL MODELS OF SOLID TUMORS MacGregor, Heather; Moogk, Duane; Xu, Stacey; Hammill, Joanne; Ip, Philbert; Wang, Ling; Shetty, Swati; MacDonald, Kyle; Shaver, Laura; Pirati, Sailaja; Lal, Prabha; Helsen, Christopher; Bramson, Jonathan; Sengupta, Sadhak; Bader, Andreas 分享 收藏
分享 收藏
Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours Hong, David S.; Kang, Yoon-Koo; Borad, Mitesh; Sachdev, Jasgit; Ejadi, Samuel; Lim, Ho Yeong; Brenner, Andrew J.; Park, Keunchil; Lee, Jae-Lyun; Kim, Tae-You; Shin, Sangjoon; Becerra, Carlos R.; Falchook, Gerald; Stoudemire, Jay; Martin, Desiree; Kelnar, Kevin; Peltier, Heidi; Bonato, Vinicius; Bader, Andreas G.; Smith, Susan; Kim, Sinil; O'Neill, Vincent; Beg, Muhammad S. 分享 收藏
分享 收藏
分享 收藏
Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors 一种脂质体miR-34a模拟物MRX34的I期研究，在晚期实体瘤患者中每周两次给药 Beg, Muhammad S.; Brenner, Andrew J.; Sachdev, Jasgit; Borad, Mitesh; Kang, Yoon-Koo; Stoudemire, Jay; Smith, Susan; Bader, Andreas G.; Kim, Sinil; Hong, David S. 分享 收藏
分享 收藏
分享 收藏
PDL1 Regulation by p53 via miR-34 Cortez, Maria Angelica; Ivan, Cristina; Valdecanas, David; Wang, Xiaohong; Peltier, Heidi J.; Ye, Yuping; Araujo, Luiz; Carbone, David P.; Shilo, Konstantin; Giri, Dipak K.; Kelnar, Kevin; Martin, Desiree; Komaki, Ritsuko; Gomez, Daniel R.; Krishnan, Sunil; Calin, George A.; Bader, Andreas G.; Welsh, James W. 分享 收藏
p53 regulation of PDL1 is mediated through miR-34a Cortez, Maria A.; Valdecanas, David; Wang, Xiaohong; Ivan, Cristina; Peltier, Heidi; Ye, Huiping; Araujo, Luiz; Carbone, David; Giri, Dipak K.; Komaki, Ritsuko; Krishnan, Sunil; Skoulidis, Ferdinandos; Heymach, John; Calin, George; Bader, Andreas G.; Welsh, James W. 分享 收藏
分享 收藏
In Vivo Delivery of miR-34a Sensitizes Lung Tumors to Radiation Through RAD51 Regulation Cortez, Maria Angelica; Valdecanas, David; Niknam, Sharareh; Peltier, Heidi J.; Diao, Lixia; Giri, Uma; Komaki, Ritsuko; Calin, George A.; Gomez, Daniel R.; Chang, Joe Y.; Heymach, John Victor; Bader, Andreas G.; Welsh, James William 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
