Nicholas J. Gay - Publications, H-index & Citations

Nicholas J. Gay

university of cambridge

47H指数

163论文数

9.4K被引数

收录论文 52

发表时间

Toll-like receptor signaling outcome is determined by the stoichiometry of the endogenous TRIFosome Toll-like受体信号传导的结果由内源性TRIFosome的化学计量比决定。

Science Advances

IF12.5

2026-03-06

OAAI

Martin C. Moncrieffe; Prasanna Suresh; Joe Boyle; Yuhao Cui; Bharti Nawalpuri; Brett Verstak; Yu P. Zhang; Ziwei Zhang; Marcus Taylor; Edward H. Egelman; Nicholas Gay; David Klenerman; Clare Bryant

Anterograde trafficking of Toll-like receptors requires the cargo sorting adaptors TMED-2 and 7

TRAFFIC

IF2.5

2023-07-26

OAAI

Holm, Julia E. J.; Soares, Sandro G.; Symmons, Martyn F.; Huddin, Afiqah Saleh; Moncrieffe, Martin C.; Gay, Nicholas J.

Activation of Toll-like receptor 4 by Ebola virus-shed glycoprotein is direct and requires the internal fusion loop but not glycosylation

CELL REPORTS

IF6.9

2022-10-01

OAAI

Scherm, Michael J.; Gangloff, Monique; Gay, Nicholas J.

Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti

NATURE COMMUNICATIONS

IF15.7

2022-08-30

OAAI

Saucereau, Yoann; Wilson, Thomas H.; Tang, Matthew C. K.; Moncrieffe, Martin C.; Hardwick, Steven W.; Chirgadze, Dimitri Y.; Soares, Sandro G.; Marcaida, Maria Jose; Gay, Nicholas J.; Gangloff, Monique

The Parkinson's disease-associated kinase LRRK2 regulates genes required for cell adhesion, polarization, and chemotaxis in activated murine macrophages

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-07-01

OAAI

Levy, Daniel R.; Udgata, Atul; Tourlomousis, Panagiotis; Symmons, Martyn F.; Hopkins, Lee J.; Bryant, Clare E.; Gay, Nicholas J.

Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain

JOURNAL OF IMMUNOLOGY

IF3.4

2020-04-15

OAAI

Lauenstein, Johannes U.; Scherm, Michael J.; Udgata, Atul; Moncrieffe, Martin C.; Fisher, David, I; Gay, Nicholas J.

Phosphorylation of the multifunctional signal transducer B-cell adaptor protein (BCAP) promotes recruitment of multiple SH2/SH3 proteins including GRB2 多功能信号转导b细胞衔接蛋白 (BCAP) 的磷酸化促进包括GRB2在内的多种SH2/SH3蛋白的募集

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-12-01

OAAI

Lauenstein, Johannes U.; Udgata, Atul; Bartram, Alex; De Sutter, Delphine; Fisher, David I.; Halabi, Samer; Eyckerman, Sven; Gay, Nicholas J.

Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells

SCIENTIFIC REPORTS

IF3.9

2019-09-11

OAAI

El Maadidi, Souhayla; Weber, Alexander N. R.; Motshwene, Precious; Schuessler, Jan Moritz; Backes, Daniel; Dickhoefer, Sabine; Wang, Hui; Liu, Xiao; Garcia, Magno Delmiro; Taumer, Christoph; Soufi, Boumediene; Wolz, Olaf-Oliver; Klimosch, Sascha N.; Franz-Wachtel, Mirita; Macek, Boris; Gay, Nicholas J.

Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4 (vol 76, pg 3667, 2019)

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2019-07-23

OAAI

Pizzuto, Malvina; Lonez, Caroline; Baroja-Mazo, Alberto; Martinez-Banaclocha, Helios; Tourlomousis, Panagiotis; Gangloff, Monique; Pelegrin, Pablo; Ruysschaert, Jean-Marie; Gay, Nicholas J.; Bryant, Clare E.

Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2019-05-06

OAAI

Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub

ELIFE

IF0

2018-01-24

OAAI

Latty, Sarah Louise; Sakai, Jiro; Hopkins, Lee; Verstak, Brett; Paramo, Teresa; Berglund, Nils A.; Cammarota, Eugenia; Cicuta, Pietro; Gay, Nicholas J.; Bond, Peter J.; Klenerman, David; Bryant, Clare E.

Targeting and Recognition of Toll-Like Receptors by Plant and Pathogen Lectins 植物和病原体凝集素对Toll样受体的靶向和识别

FRONTIERS IN IMMUNOLOGY

IF5.9

2017-12-18

OAAI

Ricci-Azevedo, Rafael; Roque-Barreira, Maria-Cristina; Gay, Nicholas J.

Kek-6: A truncated-Trk-like receptor for Drosophila neurotrophin 2 regulates structural synaptic plasticity

PLOS GENETICS

IF3.7

2017-08-28

OAAI

Ulian-Benitez, Suzana; Bishop, Simon; Foldi, Istvan; Wentzell, Jill; Okenwa, Chinenye; Forero, Manuel G.; Zhu, Bangfu; Moreira, Marta; Phizacklea, Mark; McIlroy, Graham; Li, Guiyi; Gay, Nicholas J.; Hidalgo, Alicia

Three-tier regulation of cell number plasticity by neurotrophins and Tolls in Drosophila

JOURNAL OF CELL BIOLOGY

IF6.4

2017-04-03

OAAI

Foldi, Istvan; Anthoney, Niki; Harrison, Neale; Gangloff, Monique; Verstak, Brett; Nallasivan, Mohanakarthik Ponnadai; AlAhmed, Samaher; Zhu, Bangfu; Phizacklea, Mark; Losada-Perez, Maria; Moreira, Marta; Gay, Nicholas J.; Hidalgo, Alicia

Toll-like receptor 2 promiscuity is responsible for the immunostimulatory activity of nucleic acid nanocarriers

JOURNAL OF CONTROLLED RELEASE

IF11.5

2017-02-01

OAAI

Pizzuto, Malvina; Gangloff, Monique; Scherman, Daniel; Gay, Nicholas J.; Escriou, Virginie; Ruysschaert, Jean-Marie; Lonez, Caroline

Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-01-01

OAAI

Halabi, Samer; Sekine, Eiki; Verstak, Brett; Gay, Nicholas J.; Moncrieffe, Martin C.

The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold

SCIENTIFIC REPORTS

IF3.9

2016-11-23

OAAI

Dossang, Anthony C. G.; Motshwene, Precious G.; Yang, Yang; Symmons, Martyn F.; Bryant, Clare E.; Borman, Satty; George, Julie; Weber, Alexander N. R.; Gay, Nicholas J.

Yeast expressed ArtinM shares structure, carbohydrate recognition, and biological effects with native ArtinM

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2016-01-01

OAAI

Cecilio, Nerry Tatiana; Carvalho, Fernanda Caroline; Liu, Yan; Moncrieffe, Martin; de Almeida Buranello, Patricia Andressa; Zorzetto-Fernandes, Andre Luiz; Dalle Luche, Douglas; Hanna, Ebert Seixas; Soares, Sandro Gomes; Feizi, Ten; Gay, Nicholas J.; Goldman, Maria Helena S.; Roque-Barreira, Maria Cristina

Toll-like receptor signalling through macromolecular protein complexes 通过大分子蛋白复合物的Toll样受体信号传导

MOLECULAR IMMUNOLOGY

IF3

2015-02-01

PREAI

Bryant, Clare E.; Symmons, Martyn; Gay, Nicholas J.

Therapeutic Administration of Recombinant Paracoccin Confers Protection against Paracoccidioides brasiliensis Infection: Involvement of TLRs

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2014-12-04

OAAI

Paiva Alegre-Maller, Ana Claudia; Mendonca, Flavia Costa; da Silva, Thiago Aparecido; Oliveira, Aline Ferreira; Freitas, Mateus Silveira; Hanna, Ebert Seixas; Almeida, Igor C.; Gay, Nicholas J.; Roque-Barreira, Maria Cristina

研究方向