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A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma Smith, Dirk; Helgason, Hannes; Sulem, Patrick; Bjornsdottir, Unnur Steina; Lim, Ai Ching; Sveinbjornsson, Gardar; Hasegawa, Haruki; Brown, Michael; Ketchem, Randal R.; Gavala, Monica; Garrett, Logan; Jonasdottir, Adalbjorg; Jonasdottir, Aslaug; Sigurdsson, Asgeir; Magnusson, Olafur T.; Eyjolfsson, Gudmundur I.; Olafsson, Isleifur; Onundarson, Pall Torfi; Sigurdardottir, Olof; Gislason, David; Gislason, Thorarinn; Ludviksson, Bjorn Runar; Ludviksdottir, Dora; Boezen, H. Marike; Heinzmann, Andrea; Krueger, Marcus; Porsbjerg, Celeste; Ahluwalia, Tarunveer S.; Waage, Johannes; Backer, Vibeke; Deichmann, Klaus A.; Koppelman, Gerard H.; Bonnelykke, Klaus; Bisgaard, Hans; Masson, Gisli; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel F.; Johnston, James A.; Jonsdottir, Ingileif; Stefansson, Kari 分享 收藏
Large-scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes Tyler, Matthew A.; Russell, Chris B.; Smith, Dirk E.; Rottman, James B.; Dietz, Caroline J. Padro; Hu, Xuguang; Citardi, Martin J.; Fakhri, Samer; Assassi, Shervin; Luong, Amber 分享 收藏
IL-33 Drives Augmented Responses to Ozone in Obese Mice Mathews, Joel A.; Krishnamoorthy, Nandini; Kasahara, David Itiro; Cho, Youngji; Wurmbrand, Allison Patricia; Ribeiro, Luiza; Smith, Dirk; Umetsu, Dale; Levy, Bruce D.; Shore, Stephanie Ann 分享 收藏
Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine-driven inflammation and fibrosis Vannella, Kevin M.; Ramalingam, Thirumalai R.; Borthwick, Lee A.; Barron, Luke; Hart, Kevin M.; Thompson, Robert W.; Kindrachuk, Kristen N.; Cheever, Allen W.; White, Sandra; Budelsky, Alison L.; Comeau, Michael R.; Smith, Dirk E.; Wynn, Thomas A. 分享 收藏
Physiology of severe vs. mild-moderate U-BIOPRED cohorts interpreted using a computational model Ingenito, Edward; Bigler, Jeanette; Smith, Dirk; Adcock, Ian; Rowe, Anthony; Chung, Fan; Djukanovic, Ratko; Sousa, Ana; Sterk, Peter; Nirula, Ajay 分享 收藏
Characteristics of asthma in U-BIOPRED severe and non-severe cohorts with distinct biomarker profiles Ingenito, Edward; Bigler, Jeanette; Smith, Dirk; Rowe, Anthony; Chung, Fan; Djukanovic, Ratko; Sousa, Ana; Adcock, Ian; Sterk, Peter; Nirula, Ajay 分享 收藏
Research in progress: Medical Research Council United Kingdom Refractory Asthma Stratification Programme (RASP-UK) 研究进展: 英国医学研究理事会难治性哮喘分层计划 (RASP-UK) Heaney, Liam G.; Djukanovic, Ratko; Woodcock, Ashley; Walker, Samantha; Matthews, John G.; Pavord, Ian D.; Bradding, Peter; Niven, Robert; Brightling, Chris E.; Chaudhuri, Rekha; Arron, Joseph R.; Choy, David F.; Cowan, Douglas; Mansur, Adel; Menzies-Gow, Andrew; Adcock, Ian; Chung, Kian F.; Corrigan, Chris; Coyle, Peter; Harrison, Timothy; Johnston, Sebastian; Howarth, Peter; Lordan, James; Sabroe, Ian; Bigler, Jeannette; Smith, Dirk; Catley, Matthew; May, Richard; Pierre, Lisa; Stevenson, Chris; Crater, Glenn; Keane, Frank; Costello, Richard W.; Hudson, Val; Supple, David; Hardman, Tim 分享 收藏
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ATHEROSCLEROSIS SEVERITY IS INDEPENDENT OF ENDOGENOUS IL-33 SIGNALLING Martin, P.; Palmer, G.; Rodriguez, E.; Woldt, E.; Mean, I.; Talabot-Ayer, D.; James, R. W.; Smith, D.; Kwak, B. R.; Gabay, C. 分享 收藏
The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm Hirota, Jeremy A.; Gold, Matthew J.; Hiebert, Paul R.; Parkinson, Leigh G.; Wee, Tracee; Smith, Dirk; Hansbro, Phil M.; Carlsten, Chris; VanEeden, Stephan; Sin, Don D.; McNagny, Kelly M.; Knight, Darryl A. 分享 收藏
Atherosclerosis severity is independent of endogenous IL-33 signaling Martin, Praxedis; Palmer, Gaby; Rodriguez, Emiliana; Woldt, Estelle; Mean, Isabelle; Talabot-Ayer, Dominique; James, Richard W.; Smith, Dirk; Kwak, Brenda R.; Gabay, Cem 分享 收藏
Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33 Lai, Ying; Altemeier, William A.; Vandree, John; Piliponsky, Adrian M.; Johnson, Brian; Appel, Cara L.; Frevert, Charles W.; Hyde, Dallas M.; Ziegler, Steven F.; Smith, Dirk E.; Henderson, William R., Jr.; Gelb, Michael H.; Hallstrand, Teal S. 分享 收藏
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IL-33 and ST2 KO mice display different phenotypes in K/BxN serum transfer-induced arthritis Martin, P.; Talabot-Ayer, D.; Seemayer, C. A.; Vigne, S.; Lamacchia, C.; Rodriguez, E.; Strebel, D.; Bochet, V.; Smith, D. E.; Gabay, C.; Palmer, G. 分享 收藏
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