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Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard Pipeline Olympics：针对DNA甲基化测序数据，基于实验金标准的可延续性计算工作流基准测试 Lin, Yu-Yu; Breuer, Kersten; Weichenhan, Dieter; Lafrenz, Pascal; Sarnataro, Antonella; Wilk, Agata; Chepeleva, Maryna; Mucke, Oliver; Schonung, Maximilian; Petermann, Franziska; Kensche, Philip Reiner; Weiser, Lena; Thommen, Frank; Giacomelli, Gideon; Nordstroem, Karl; Gonzalez-Avalos, Edahi; Merkel, Angelika; Kretzmer, Helene; Fischer, Jonas; Kramer, Stephen; Iskar, Murat; Wolf, Stephan; Buchhalter, Ivo; Esteller, Manel; Lawerenz, Christian; Twardziok, Sven; Zapatka, Marc; Hovestadt, Volker; Schlesner, Matthias; Schulz, Marcel H.; Hoffmann, Steve; Gerhauser, Clarissa; Walter, Jorn; Hartmann, Mark; Lipka, Daniel B.; Assenov, Yassen; Bock, Christoph; Plass, Christoph; Toth, Reka; Lutsik, Pavlo 分享 收藏
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer Vlachavas, Efstathios-Iason; Voutetakis, Konstantinos; Kosmidou, Vivian; Tsikalakis, Spyridon; Roditis, Spyridon; Pateas, Konstantinos; Kim, Ryangguk; Pagel, Kymberleigh; Wolf, Stephan; Warsow, Gregor; Dimitrakopoulou-Strauss, Antonia; Zografos, Georgios N.; Pintzas, Alexander; Betge, Johannes; Papadodima, Olga; Wiemann, Stefan 分享 收藏
Persister cell phenotypes contribute to poor patient outcomes after neoadjuvant chemotherapy in PDAC 持续细胞表型导致PDAC新辅助化疗后患者预后不佳 Zhou, Xu; An, Jingyu; Kurilov, Roma; Brors, Benedikt; Hu, Kai; Peccerella, Teresa; Roessler, Stephanie; Pfuetze, Katrin; Schulz, Angela; Wolf, Stephan; Hohmann, Nicolas; Theile, Dirk; Sauter, Max; Burhenne, Juergen; Ei, Shigenori; Heger, Ulrike; Strobel, Oliver; Barry, Simon T.; Springfeld, Christoph; Tjaden, Christine; Bergmann, Frank; Buechler, Markus; Hackert, Thilo; Fortunato, Franco; Neoptolemos, John P.; Bailey, Peter 分享 收藏
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Hspa4l-deficient mice display increased incidence of male infertility and hydronephrosis development Held, Torsten; Paprotta, Ilona; Khulan, Janchiv; Hemmerlein, Bernhardt; Binder, Lutz; Wolf, Stephan; Schubert, Stephanie; Meinhardt, Andreas; Engel, Wolfgang; Adham, Ibrahim M. 分享 收藏
COGNITION: a prospective precision oncology trial for patients with early breast cancer at high risk following neoadjuvant chemotherapy 认知: 新辅助化疗后高危早期乳腺癌患者的前瞻性精确肿瘤学试验 Pixberg, C.; Zapatka, M.; Hlevnjak, M.; Benedetto, S.; Suppelna, J. P.; Heil, J.; Smetanay, K.; Michel, L.; Fremd, C.; Koerber, V; Ruebsam, M.; Buschhorn, L.; Heublein, S.; Schaefgen, B.; Golatta, M.; Gomez, C.; von Au, A.; Wallwiener, M.; Wolf, S.; Dikow, N.; Schaaf, C.; Gutjahr, E.; Allgaeuer, M.; Stenzinger, A.; Pfuetze, K.; Kirsten, R.; Huebschmann, D.; Sinn, H-P; Jaeger, D.; Trumpp, A.; Schlenk, R.; Hoefer, T.; Thewes, V; Schneeweiss, A.; Lichter, P. 分享 收藏
Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers Jahn, A.; Rump, A.; Widmann, T. J.; Heining, C.; Horak, P.; Hutter, B.; Paramasivam, N.; Uhrig, S.; Gieldon, L.; Drukewitz, S.; Kuebler, A.; Bermudez, M.; Hackmann, K.; Porrmann, J.; Wagner, J.; Arlt, M.; Franke, M.; Fischer, J.; Kowalzyk, Z.; William, D.; Weth, V.; Oster, S.; Froehlich, M.; Huellein, J.; Gonzalez, C. Valle; Kreutzfeldt, S.; Mock, A.; Heilig, C. E.; Lipka, D. B.; Moehrmann, L.; Hanf, D.; Oles, M.; Teleanu, V.; Allgaeuer, M.; Ruhnke, L.; Kutz, O.; Knurr, A.; Lassmann, A.; Endris, V.; Neumann, O.; Penzel, R.; Beck, K.; Richter, D.; Winter, U.; Wolf, S.; Pfuetze, K.; Geoerg, C.; Meissburger, B.; Buchhalter, I.; Augustin, M.; Aulitzky, W. E.; Hohenberger, P.; Kroiss, M.; Schirmacher, P.; Schlenk, R. F.; Keilholz, U.; Klauschen, F.; Folprecht, G.; Bauer, S.; Siveke, J. T.; Brandts, C. H.; Kindler, T.; Boerries, M.; Illert, A. L.; von Bubnoff, N.; Jost, P. J.; Metzeler, K. H.; Bitzer, M.; Schulze-Osthoff, K.; von Kalle, C.; Brors, B.; Stenzinger, A.; Weichert, W.; Huebschmann, D.; Froehling, S.; Glimm, H.; Schroeck, E.; Klink, B. 分享 收藏
The genomic and transcriptional landscape of primary central nervous system lymphoma Radke, Josefine; Ishaque, Naveed; Koll, Randi; Gu, Zuguang; Schumann, Elisa; Sieverling, Lina; Uhrig, Sebastian; Huebschmann, Daniel; Toprak, Umut H.; Lopez, Cristina; Hostench, Xavier Pastor; Borgoni, Simone; Juraeva, Dilafruz; Pritsch, Fabienne; Paramasivam, Nagarajan; Balasubramanian, Gnana Prakash; Schlesner, Matthias; Sahay, Shashwat; Weniger, Marc; Pehl, Debora; Radbruch, Helena; Osterloh, Anja; Korfel, Agnieszka; Misch, Martin; Onken, Julia; Faust, Katharina; Vajkoczy, Peter; Moskopp, Dag; Wang, Yawen; Joedicke, Andreas; Truemper, Lorenz; Anagnostopoulos, Ioannis; Lenze, Dido; Kueppers, Ralf; Hummel, Michael; Schmitt, Clemens A.; Wiestler, Otmar D.; Wolf, Stephan; Unterberg, Andreas; Eils, Roland; Herold-Mende, Christel; Brors, Benedikt; Siebert, Reiner; Wiemann, Stefan; Heppner, Frank L. 分享 收藏
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The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets 儿科精确肿瘤学信息注册中心: 具有非常高证据目标的患者的临床结果和益处 van Tilburg, Cornelis M.; Pfaff, Elke; Pajtler, Kristian W.; Langenberg, Karin P. S.; Fiesel, Petra; Jones, Barbara C.; Balasubramanian, Gnana Prakash; Stark, Sebastian; Johann, Pascal D.; Blattner-Johnson, Mirjam; Schramm, Kathrin; Dikow, Nicola; Hirsch, Steffen; Sutter, Christian; Grund, Kerstin; von Stackelberg, Arend; Kulozik, Andreas E.; Lissat, Andrej; Borkhardt, Arndt; Meisel, Roland; Reinhardt, Dirk; Klusmann, Jan-Henning; Fleischhack, Gudrun; Tippelt, Stephan; von Schweinitz, Dietrich; Schmid, Irene; Kramm, Christof M.; von Bueren, Andre O.; Calaminus, Gabriele; Vorwerk, Peter; Graf, Norbert; Westermann, Frank; Fischer, Matthias; Eggert, Angelika; Burkhardt, Birgit; Woessmann, Wilhelm; Nathrath, Michaela; Hecker-Nolting, Stefanie; Fruehwald, Michael C.; Schneider, Dominik T.; Brecht, Ines B.; Ketteler, Petra; Fulda, Simone; Koscielniak, Ewa; Meister, Michael T.; Scheer, Monika; Hettmer, Simone; Schwab, Matthias; Tremmel, Roman; Ora, Ingrid; Hutter, Caroline; Gerber, Nicolas U.; Lohi, Olli; Kazanowska, Bernarda; Kattamis, Antonis; Filippidou, Maria; Goemans, Bianca; Zwaan, C. Michel; Milde, Till; Jaeger, Natalie; Wolf, Stephan; Reuss, David; Sahm, Felix; von Deimling, Andreas; Dirksen, Uta; Freitag, Angelika; Witt, Ruth; Lichter, Peter; Kopp-Schneider, Annette; Jones, David T. W.; Molenaar, Jan J.; Capper, David; Pfister, Stefan M.; Witt, Olaf 分享 收藏
Autonomic Nervous System Activity during Refractory Rise in Intracranial Pressure Fedriga, Marta; Czigler, Andras; Nasr, Nathalie; Zeiler, Frederick. A.; Park, Soojin; Donnelly, Joseph; Papaioannou, Vasilios; Frisvold, Shirin K.; Wolf, Stephan; Rasulo, Frank; Sykora, Marek; Smielewski, Peter; Czosnyka, Marek 分享 收藏
Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers 全面的基因组和转录组学分析可指导罕见癌症患者的治疗决策 Horak, Peter; Heining, Christoph; Kreutzfeldt, Simon; Hutter, Barbara; Mock, Andreas; Huellein, Jennifer; Froehlich, Martina; Uhrig, Sebastian; Jahn, Arne; Rump, Andreas; Gieldon, Laura; Moehrmann, Lino; Hanf, Dorothea; Teleanu, Veronica; Heilig, Christoph E.; Lipka, Daniel B.; Allgaeuer, Michael; Ruhnke, Leo; Lassmann, Andreas; Endris, Volker; Neumann, Olaf; Penzel, Roland; Beck, Katja; Richter, Daniela; Winter, Ulrike; Wolf, Stephan; Pfuetze, Katrin; Geoerg, Christina; Meissburger, Bettina; Buchhalter, Ivo; Augustin, Marinela; Aulitzky, Walter E.; Hohenberger, Peter; Kroiss, Matthias; Schirmacher, Peter; Schlenk, Richard F.; Keilholz, Ulrich; Klauschen, Frederick; Folprecht, Gunnar; Bauer, Sebastian; Siveke, Jens Thomas; Brandts, Christian H.; Kindler, Thomas; Boerries, Melanie; Illert, Anna L.; von Bubnoff, Nikolas; Jost, Philipp J.; Spiekermann, Karsten; Bitzer, Michael; Schulze-Osthoff, Klaus; von Kalle, Christof; Klink, Barbara; Brors, Benedikt; Stenzinger, Albrecht; Schroeck, Evelin; Huebschmann, Daniel; Weichert, Wilko; Glimm, Hanno; Froehling, Stefan 分享 收藏
Rare germline variants in the E-cadherin gene CDH1 are associated with the risk of brain tumors of neuroepithelial and epithelial origin E-cadherin基因CDH1的罕见种系变异与神经上皮和上皮起源的脑肿瘤的风险相关 Foerster, Alisa; Brand, Frank; Banan, Rouzbeh; Hueneburg, Robert; Weber, Christine A. M.; Ewert, Wiebke; Kronenberg, Jessica; Previti, Christopher; Elyan, Natalie; Beyer, Ulrike; Martens, Helge; Hong, Bujung; Braesen, Jan H.; Erbersdobler, Andreas; Krauss, Joachim K.; Stangel, Martin; Samii, Amir; Wolf, Stephan; Preller, Matthias; Aretz, Stefan; Wiese, Bettina; Hartmann, Christian; Weber, Ruthild G. 分享 收藏
Comprehensive genomic analysis of rare cancers: Results of the MASTER precision oncology trial of the German Cancer Consortium Horak, Peter; Heining, Christoph; Mock, Andreas; Kreutzfeldt, Simon; Lassmann, Andreas; Moehrmann, Lino; Huellein, Jennifer; Hanf, Dorothea; Jahn, Arne; Ruhnke, Leo; Gieldon, Laura; Heilig, Christoph E.; Teleanu, Veronica; Froehlich, Martina; Uhrig, Sebastian; Beck, Katja; Richter, Daniela; Wolf, Stephan; Pfuetze, Katrin; Geoerg, Christina; Meissburger, Bettina; Klauschen, Frederick; Keilholz, Ulrich; Ochsenreither, Sebastian; Folprecht, Gunnar; Siveke, Jens; Bauer, Sebastian; Kindler, Thomas; Brandts, Christian; Boerries, Melanie; Illert, Anna L.; von Bubnoff, Nikolas; Spiekermann, Karsten; Jost, Philipp J.; Schulze-Osthoff, Klaus; Bitzer, Michael; Schirmacher, Peter; von Kalle, Christof; Schlenk, Richard F.; Klink, Barbara; Hutter, Barbara; Huebschmann, Daniel; Stenzinger, Albrecht; Weichert, Wilko; Schroeck, Evelin; Brors, Benedikt; Glimm, Hanno; Froehling, Stefan 分享 收藏
Defective homologous recombination DNA repair as therapeutic target in advanced chordoma Groeschel, Stefan; Huebschmann, Daniel; Raimondi, Francesco; Horak, Peter; Warsow, Gregor; Froehlich, Martina; Klink, Barbara; Gieldon, Laura; Hutter, Barbara; Kleinhenz, Kortine; Bonekamp, David; Marschal, Oliver; Chudasama, Priya; Mika, Jagoda; Groth, Marie; Uhrig, Sebastian; Kraemer, Stephen; Heining, Christoph; Heilig, Christoph; Richter, Daniela; Reisinger, Eva; Pfuetze, Katrin; Eils, Roland; Wolf, Stephan; von Kalle, Christof; Brandts, Christian; Scholl, Claudia; Weichert, Wilko; Richter, Stephan; Bauer, Sebastian; Penzel, Roland; Schroeck, Evelin; Stenzinger, Albrecht; Schlenk, Richard; Brors, Benedikt; Russell, Robert; Glimm, Hanno; Schlesner, Matthias; Froehling, Stefan 分享 收藏
Clinical relevance of comprehensive genomic analysis in advanced-stage cancers and rare malignancies: Results from the MASTER trial of the German Cancer Consortium Horak, Peter; Heining, Christoph; Kreutzfeldt, Simon; Heilig, Christoph E.; Moehrmann, Lino; Gieldon, Laura; Froehlich, Martina; Uhrig, Sebastian; Huebschmann, Daniel; Beck, Katja; Richter, Daniela; Wolf, Stephan; Pfuetze, Katrin; Geoerg, Christina; Meissburger, Bettina; Klauschen, Frederick; Ochsenreither, Sebastian; Folprecht, Gunnar; Siveke, Jens; Bauer, Sebastian; Kindler, Thomas; Brandts, Christian; Boerries, Melanie; von Bubnoff, Nikolas; Spiekermann, Karsten; Jost, Philipp J.; Schulze-Osthoff, Klaus; Bitzer, Michael; Schirmacher, Peter; von Kalle, Christof; Schlenk, Richard; Klink, Barbara; Flutter, Barbara; Weichert, Wilko; Stenzinger, Albrecht; Schroeck, Evelin; Brors, Benedikt; Glimm, Hanno; Froehling, Stefan 分享 收藏
Defective homologous recombination DNA repair as therapeutic target in advanced chordoma Groesche, Stefan; Huebschmann, Daniel; Raimondi, Francesco; Horak, Peter; Warsow, Gregor; Froehlich, Martina; Klink, Barbara; Gieldon, Laura; Hutter, Barbara; Kleinheinz, Kortine; Bonekamp, David; Marschal, Oliver; Chudasama, Priya; Mika, Jagoda; Groth, Marie; Uhri, Sebastian; Kraemer, Stephen; Heining, Christoph; Heilig, Christoph E.; Richter, Daniela; Reisinger, Eva; Pfuetze, Katrin; Eils, Roland; Wolf, Stephan; von Kalle, Christof; Brandts, Christian; Scholl, Claudia; Weichert, Wilko; Richter, Stephan; Bauer, Sebastian; Penze, Roland; Schroeck, Evelin; Stenzinger, Albrecht; Schlenk, Richard F.; Brors, Benedikt; Russell, Robert B.; Glimm, Hanno; Schlesner, Matthias; Froehling, Stefan 分享 收藏
Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients Greif, Philipp A.; Hartmann, Luise; Vosberg, Sebastian; Stief, Sophie M.; Mattes, Raphael; Hellmann, Ines; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Kerbs, Paul; Jurinovic, Vindi; Schumacher, Daniela; Pastore, Friederike; Braeundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Neumann, Martin; Baldus, Claudia D.; Bohlander, Stefan K.; Wolf, Stephan; Goerlich, Dennis; Berdel, Wolfgang E.; Woermann, Bernhard J.; Hiddemann, Wolfgang; Spiekermann, Karsten 分享 收藏
Integrative genomic and transcriptomic analysis of leiomyosarcoma Chudasama, Priya; Mughal, Sadaf S.; Sanders, Mathijs A.; Huebschmann, Daniel; Chung, Inn; Deeg, Katharina I.; Wong, Siao-Han; Rabe, Sophie; Hlevnjak, Mario; Zapatka, Marc; Ernst, Aurelie; Kleinheinz, Kortine; Schlesner, Matthias; Sieverling, Lina; Klink, Barbara; Schroeck, Evelin; Hoogenboezem, Remco M.; Kasper, Bernd; Heilig, Christoph E.; Egerer, Gerlinde; Wolf, Stephan; von Kalle, Christof; Eils, Roland; Stenzinger, Albrecht; Weichert, Wilko; Glimm, Hanno; Groeschel, Stefan; Kopp, Hans-Georg; Omlor, Georg; Lehner, Burkhard; Bauer, Sebastian; Schimmack, Simon; Ulrich, Alexis; Mechtersheimer, Gunhild; Rippe, Karsten; Brors, Benedikt; Hutter, Barbara; Renner, Marcus; Hohenberger, Peter; Scholl, Claudia; Froehling, Stefan 分享 收藏
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