未登录 Aprocitentan in Patients With Chronic Kidney Disease and Resistant Hypertension 阿普西特坦在慢性肾脏病和难治性高血压患者中的应用 Rossignol, Patrick; Clozel, Martine; Dreier, Roland F.; Flack, John M.; Flamion, Bruno; Mann, Johannes; Narkiewicz, Krzysztof; Sassi-Sayadi, Mouna; Wang, Ji-Guang; Weber, Michael A.; Schlaich, Markus P. 分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
Impact of high-altitude therapy on type-2 immune responses in asthma patients Boonpiyathad, Tadech; Capova, Gertruda; Duchna, Hans-Werner; Croxford, Andrew L.; Farine, Herve; Dreher, Anita; Clozel, Martine; Schreiber, Juliane; Kubena, Petr; Lunjani, Nonhlanhla; Mirer, David; Ruckert, Beate; Satitsuksanoa, Pattraporn; Tan, Ge; Groenen, Peter M. A.; Bersuch, Eugen; Akdis, Mubeccel; Strasser, Daniel S.; Renner, Ellen D.; Akdis, Cezmi A. 分享 收藏
Pharmacological Characterization of Aprocitentan, a Dual Endothelin Receptor Antagonist, Alone and in Combination with Blockers of the Renin Angiotensin System, in Two Models of Experimental Hypertension Trensz, Frederic; Bortolamiol, Celine; Kramberg, Markus; Wanner, Daniel; Hadana, Hakim; Rey, Markus; Strasser, Daniel S.; Delahaye, Stephane; Hess, Patrick; Vezzali, Enrico; Mentzel, Ulrich; Menard, Joel; Clozel, Martine; Iglarz, Marc 分享 收藏
分享 收藏
Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low β-Arrestin Recruitment and Desensitization Potential Gatfield, John; Menyhart, Katalin; Wanner, Daniel; Gnerre, Carmela; Monnier, Lucile; Morrison, Keith; Hess, Patrick; Iglarz, Marc; Clozel, Martine; Nayler, Oliver 分享 收藏
Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retentions Vercauteren, Magali; Trensz, Frederic; Pasquali, Anne; Cattaneo, Christophe; Strasser, Daniel S.; Hess, Patrick; Iglarz, Marc; Clozel, Martine 分享 收藏
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling Le Bihan, Amelie; de Kanter, Ruben; Angulo-Barturen, Inigo; Binkert, Christoph; Boss, Christoph; Brun, Reto; Brunner, Ralf; Buchmann, Stephan; Burrows, Jeremy; Dechering, Koen J.; Delves, Michael; Ewerlingl, Sonja; Ferrer, Santiago; Fischli, Christoph; Gamo-Benito, Francisco Javier; Gnadig, Nina F.; Heidmann, Bibia; Belen Jimenez-Diaz, Maria; Leroy, Didier; Santos Martinez, Maria; Meyer, Solange; Moehrle, Joerg J.; Ng, Caroline L.; Noviyanti, Rintis; Ruecker, Andrea; Maria Sanz, Laura; Sauerwein, Robert W.; Scheurer, Christian; Schleiferboeck, Sarah; Sinden, Robert; Snyder, Christopher; Straimer, Judith; Wirjanata, Grennady; Marfurt, Jutta; Price, Ric N.; Weller, Thomas; Fischli, Walter; Fidock, David A.; Clozel, Martine; Wittlin, Sergio 分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
The Discovery of N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N′-propylsulfamide (Macitentan), an Orally Active, Potent Dual Endothelin Receptor Antagonist Bolli, Martin H.; Boss, Christoph; Binkert, Christoph; Buchmann, Stephan; Bur, Daniel; Hess, Patrick; Iglarz, Marc; Meyer, Solange; Rein, Josiane; Rey, Markus; Treiber, Alexander; Clozel, Martine; Fischli, Walter; Weller, Thomas 分享 收藏
分享 收藏
Identification of Cathepsin L as a Potential Sex-Specific Biomarker for Renal Damage Bauer, Yasmina; Hess, Patrick; Qiu, Changbin; Klenk, Axel; Renault, Berengere; Wanner, Daniel; Studer, Rolf; Killer, Nina; Stalder, Anna Katharina; Stritt, Manuel; Strasser, Daniel Stefan; Farine, Herve; Kauser, Katalin; Clozel, Martine; Fischli, Walter; Nayler, Oliver 分享 收藏
分享 收藏
Pharmacology of Macitentan, an Orally Active Tissue-Targeting Dual Endothelin Receptor Antagonist Iglarz, Marc; Binkert, Christoph; Morrison, Keith; Fischli, Walter; Gatfield, John; Treiber, Alexander; Weller, Thomas; Bolli, Martin H.; Boss, Christoph; Buchmann, Stephan; Capeleto, Bruno; Hess, Patrick; Qiu, Changbin; Clozel, Martine 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
