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P

Peter Böhlen

Eli Lilly

92H指数
291论文数
3.4W被引数
收录论文 31
发表时间
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Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2芳基酞嗪作为VEGFR-2的有效和口服生物可利用的抑制剂
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2009-01-01
err43
PREAI
errDuncton, Matthew A. J.; Chekler, Eugene L. Piatnitski; Katoch-Rouse, Reeti; Sherman, Dan; Wong, Wai C.; Smith, Leon M., II; Kawakami, Joel K.; Kiselyov, Alexander S.; Milligan, Daniel L.; Balagtas, Chris; Hadari, Yaron R.; Wang, Ying; Patel, Sheetal N.; Rolster, Robin L.; Tonra, James R.; Surguladze, David; Mitelman, Stan; Kussie, Paul; Bohlen, Peter; Doody, Jacqueline F.
err分享
err收藏
Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity (vol 105, pg R15, 2000)
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2006-10-02
err2
errOAAI
errKlement, Giannoula; Baruchel, Sylvain; Rak, Janusz; Man, Shan; Clark, Katherine; Hicklin, Daniel J.; Bohlen, Peter; Kerbel, Robert S.
err分享
err收藏
The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma
errINTERNATIONAL JOURNAL OF CANCER
IF4.7
err2006-07-18
err176
errOAAI
errWu, Yan; Hooper, Andrea T.; Zhong, Zhaojing; Witte, Larry; Bohlen, Peter; Rafii, Shahin; Hicklin, Daniel J.
err分享
err收藏
Activation of FGFR1β signaling pathway promotes survival, migration and resistance to chemotherapy in acute myeloid leukemia cells
errLEUKEMIA
IF13.4
err2006-04-06
err57
PREAI
errKarajannis, M. A.; Vincent, L.; DiRenzo, R.; Shmelkov, S. V.; Zhang, F.; Feldman, E. J.; Bohlen, P.; Zhu, Z.; Sun, H.; Kussie, P.; Rafii, S.
err分享
err收藏
Inhibition of glioblastoma angiogenesis and invasion by combined treatments directed against vascular endothelial growth factor receptor-2, epidermal growth factor receptor, and vascular endothelial-cadherin
errCLINICAL CANCER RESEARCH
IF10.2
err2005-07-06
err93
PREAI
errLamszus, K; Brockmann, MA; Eckerich, C; Bohlen, P; May, C; Mangold, U; Fillbrandt, R; Westphal, M
err分享
err收藏
A fully human recombinant IgG-like bispecific antibody to both the epidermal growth factor receptor and the insulin-like growth factor receptor for enhanced antitumor activity
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2005-05-01
err346
errOAAI
errLu, D; Zhang, HF; Koo, H; Tonra, J; Balderes, P; Prewett, M; Corcoran, E; Mangalampalli, V; Bassi, R; Anselma, D; Patel, D; Kang, XQ; Ludwig, DL; Hicklin, DJ; Bohlen, P; Witte, L; Zhu, ZP
err分享
err收藏
Fetal stromal-dependent paracrine and intracrine vascular endothelial growth factor-A/vascular endothelial growth factor receptor-1 signaling promotes proliferation and motility of human primary myeloma cells
errCANCER RESEARCH
IF16.6
err2005-04-15
err54
PREAI
errVincent, L; Jin, DK; Karajannis, MA; Shido, K; Hooper, AT; Rashbaum, WK; Pytowski, B; Wu, Y; Hicklin, DJ; Zhu, ZP; Bohlen, P; Niesvizky, R; Rafii, S
err分享
err收藏
Inhibition of the vascular endothelial cell (VE)-specific adhesion molecule VE-cadherin blocks gonadotropin-dependent folliculogenesis and corpus luteum formation and angiogenesis
errENDOCRINOLOGY
IF3.3
err2005-03-01
err22
errOAAI
errNakhuda, GS; Zimmermann, RC; Bohlen, P; Liao, F; Sauer, MV; Kitajewski, J
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err收藏
The vascular endothelial growth factor (VEGF) VEGF receptor 2 pathway is critical for blood vessel survival in corpora lutea of pregnancy in the rodent
errENDOCRINOLOGY
IF3.3
err2005-03-01
err98
errOAAI
errPauli, SA; Tang, HY; Wang, J; Bohlen, P; Posser, R; Hartman, T; Sauer, MV; Kitajewski, J; Zimmermann, RC
err分享
err收藏
Angiogenesis inhibition by vascular endothelial growth factor receptor-2 blockade reduces stromal matrix metal loproteinase expression, normalizes stromal tissue, and reverts epithelial tumor phenotype in surface heterotransplants
errCANCER RESEARCH
IF16.6
err2005-02-25
err113
errOAAI
errVosseler, S; Mirancea, N; Bohlen, P; Mueller, MM; Fusenig, NE
err分享
err收藏
VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the α1β1 and α2β1 integrins
errFASEB JOURNAL
IF4.2
err2004-05-07
err288
PREAI
errHong, YK; Lange-Asschenfeldt, B; Velasco, P; Hirakawa, S; Kunstfeld, R; Brown, LF; Bohlen, P; Senger, DR; Detmar, M
err分享
err收藏
Dynamic contrast-enhanced magnetic resonance imaging rapidly indicates vessel regression in human squamous cell carcinomas grown in nude mice caused by VEGF receptor 2 blockade with DC101
errNEOPLASIA
IF7.7
err2004-05-01
err63
errOAAI
errKiessling, F; Farhan, N; Lichy, MP; Vosseler, S; Heilmann, M; Krix, M; Bohlen, P; Miller, DW; Mueller, MM; Semmler, W; Fusenig, NE; Delorme, S
err分享
err收藏
Simultaneous blockade of both the epidermal growth factor receptor and the insulin-like growth factor receptor signaling pathways in cancer cells with a fully human recombinant bispecific antibody
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2004-01-01
err278
errOAAI
errLu, D; Zhang, HF; Ludwig, D; Persaud, A; Jimenez, X; Burtrum, D; Balderes, P; Liu, ML; Bohlen, P; Witte, L; Zhu, ZP
err分享
err收藏
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis
errNATURE MEDICINE
IF50
err2003-12-21
err710
PREAI
errAvecilla, ST; Hattori, K; Heissig, B; Tejada, R; Liao, F; Shido, K; Jin, DK; Dias, S; Zhang, F; Hartman, TE; Hackett, NR; Crystal, RG; Witte, L; Hicklin, DJ; Bohlen, P; Eaton, D; Lyden, D; de Sauvage, F; Rafii, S
err分享
err收藏
Monoclonal antibody therapeutics and apoptosis
errONCOGENE
IF7.3
err2003-12-08
err70
PREAI
errLudwig, DL; Pereira, DS; Zhu, ZP; Hicklin, DJ; Bohlen, P
err分享
err收藏
Blockade of vascular endothelial growth factor receptor I (VEGF-RI), but not VEGF-RII, suppresses joint destruction in the K/BxN model of rheumatoid arthritis
errJOURNAL OF IMMUNOLOGY
IF3.4
err2003-11-01
err114
errOAAI
errDe Bandt, M; Ben Mahdi, MH; Ollivier, V; Grossin, M; Dupuis, M; Gaudry, M; Bohlen, P; Lipson, KE; Rice, A; Wu, Y; Gougerot-Pocidalo, MA; Pasquier, C
err分享
err收藏
Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2003-10-01
err232
errOAAI
errLu, D; Shen, JQ; Vil, MD; Zhang, HF; Jimenez, X; Bohlen, P; Witte, L; Zhu, ZP
err分享
err收藏
Vascular endothelial growth factor receptor 2-mediated angiogenesis is essential for gonadotropin-dependent follicle development
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2003-09-01
err116
errOAAI
errZimmermann, RC; Hartman, T; Kavic, S; Pauli, SA; Bohlen, P; Sauer, MV; Kitajewski, J
err分享
err收藏
Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity用针对血管内皮生长因子受体2的人抗体在动物模型中抑制人白血病。抗体亲和力与生物活性的相关性
errLEUKEMIA
IF13.4
err2003-03-19
err195
errOAAI
errZhu, Z; Hattori, K; Zhang, H; Jimenez, X; Ludwig, DL; Dias, S; Kussie, P; Koo, H; Kim, HJ; Lu, D; Liu, M; Tejada, R; Friedrich, M; Bohlen, P; Witte, L; Rafii, S
err分享
err收藏
Treatment of pancreatic cancer xenografts with erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation
errINTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
IF6.5
err2002-11-01
err120
PREAI
errBuchsbaum, DJ; Bonner, JA; Grizzle, WE; Stackhouse, MA; Carpenter, M; Hicklin, DJ; Bohlen, P; Raisch, KP
err分享
err收藏

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