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Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo Reuberson, James; Horsley, Helen; Franklin, Richard J.; Ford, Daniel; Neuss, Judi; Brookings, Daniel; Huang, Qiuya; Vanderhoydonck, Bart; Gao, Ling-Jie; Jang, Mi-Yeon; Herdewijn, Piet; Ghawalkar, Anant; Fallah-Arani, Farnaz; Khan, Adnan R.; Henshall, Jamie; Jairaj, Mark; Malcolm, Sarah; Ward, Eleanor; Shuttleworth, Lindsay; Lin, Yuan; Li, Shengqiao; Louat, Thierry; Waer, Mark; Herman, Jean; Payne, Andrew; Ceska, Tom; Doyle, Carl; Pitt, Will; Calmiano, Mark; Augustin, Martin; Steinbacher, Stefan; Lammens, Alfred; Allen, Rodger 分享 收藏
Inflammatory Gene Expression Profile and Defective Interferon-γ and Granzyme K in Natural Killer Cells From Systemic Juvenile Idiopathic Arthritis Patients Put, Karen; Vandenhaute, Jessica; Avau, Anneleen; van Nieuwenhuijze, Annemarie; Brisse, Ellen; Dierckx, Tim; Rutgeerts, Omer; Garcia-Perez, Josselyn E.; Toelen, Jaan; Waer, Mark; Leclercq, Georges; Goris, An; Van Weyenbergh, Johan; Liston, Adrian; De Somer, Lien; Wouters, Carine H.; Matthys, Patrick 分享 收藏
The Leuven Immunomodulatory Protocol Promotes T-Regulatory Cells and Substantially Prolongs Survival After First Intestinal Transplantation Ceulemans, L. J.; Braza, F.; Monbaliu, D.; Jochmans, I.; De Hertogh, G.; Du Plessis, J.; Emonds, M. -P.; Kitade, H.; Kawai, M.; Li, Y.; Zhao, X.; Koshiba, T.; Sprangers, B.; Brouard, S.; Waer, M.; Pirenne, J. 分享 收藏
Mouse Cytomegalovirus Infection in BALB/c Mice Resembles Virus-Associated Secondary Hemophagocytic Lymphohistiocytosis and Shows a Pathogenesis Distinct from Primary Hemophagocytic Lymphohistiocytosis Brisse, Ellen; Imbrechts, Maya; Put, Karen; Avau, Anneleen; Mitera, Tania; Berghmans, Nele; Rutgeerts, Omer; Waer, Mark; Ninivaggi, Marisa; Kelchtermans, Hilde; Boon, Louis; Snoeck, Robert; Wouters, Carine H.; Andrei, Graciela; Matthys, Patrick 分享 收藏
RNA Profiling in Human and Murine Transplanted Hearts: Identification and Validation of Therapeutic Targets for Acute Cardiac and Renal Allograft Rejection Van Aelst, L. N. L.; Summer, G.; Li, S.; Gupta, S. K.; Heggermont, W.; De Vusser, K.; Carai, P.; Naesens, M.; Van Cleemput, J.; Van de Werf, F.; Vanhaecke, J.; Thum, T.; Waer, M.; Papageorgiou, A. -P.; Schroen, B.; Heymans, S. 分享 收藏
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γ-Hydroxyethyl piperidine iminosugar and N-alkylated derivatives: A study of their activity as glycosidase inhibitors and as immunosuppressive agents Γ-羟乙基哌啶亚氨基糖和N-烷基化衍生物: 对其作为糖苷酶抑制剂和免疫抑制剂的活性的研究 Markad, Pramod R.; Sonawane, Dhiraj P.; Ghosh, Sougata; Chopade, Balu A.; Kumbhar, Navnath; Louat, Thierry; Herman, Jean; Waer, Mark; Herdewijn, Piet; Dhavale, Dilip D. 分享 收藏
Human Multipotent Adult Progenitor Cells Are Nonimmunogenic and Exert Potent Immunomodulatory Effects on Alloreactive T-Cell Responses Jacobs, Sandra A.; Pinxteren, Jef; Roobrouck, Valerie D.; Luyckx, Ariane; van't Hof, Wouter; Deans, Robert; Verfaillie, Catherine M.; Waer, Mark; Billiau, An D.; Van Gool, Stefaan W. 分享 收藏
Synthesis of a 2,4,6-trisubstituted 5-cyano-pyrimidine library and evaluation of its immunosuppressive activity in a Mixed Lymphocyte Reaction assay Stella, Alessandro; Van Belle, Kristien; De Jonghe, Steven; Louat, Thierry; Herman, Jean; Rozenski, Jef; Waer, Mark; Herdewijn, Piet 分享 收藏
Oct4-negative multipotent adult progenitor cells and mesenchymal stem cells as regulators of T-cell alloreactivity in mice Luyckx, Ariane; De Somer, Lien; Jacobs, Sandra; Rutgeerts, Omer; Lenaerts, Caroline; Roobrouck, Valerie D.; Verfaillie, Catherine M.; Waer, Mark; Van Gool, Stefaan W.; Billiau, An D. 分享 收藏
The Vitamin D Analog, TX527, Promotes a Human CD4+CD25highCD127low Regulatory T Cell Profile and Induces a Migratory Signature Specific for Homing to Sites of Inflammation Baeke, Femke; Korf, Hannelie; Overbergh, Lut; Verstuyf, Annemieke; Thorrez, Lieven; Van Lommel, Leentje; Waer, Mark; Schuit, Frans; Gysemans, Conny; Mathieu, Chantal 分享 收藏
Discovery of 7-N-Piperazinylthiazolo[5,4-d]pyrimidine Analogues as a Novel Class of Immunosuppressive Agents with in Vivo Biological Activity Jang, Mi-Yeon; Lin, Yuan; De Jonghe, Steven; Gao, Ling-Jie; Vanderhoydonck, Bart; Froeyen, Mathy; Rozenski, Jef; Herman, Jean; Louat, Thierry; Van Belle, Kristien; Waer, Mark; Herdewijn, Piet 分享 收藏
Murine bone marrow chimeras developing autoimmunity after CTLA-4-blockade show an expansion of T regulatory cells with an activated cytokine profile CTLA-4-blockade后发生自身免疫的鼠骨髓嵌合体显示具有激活的细胞因子谱的T调节细胞的扩增 De Somer, Lien; Fevery, Sabine; Bullens, Dominique M. A.; Rutgeerts, Omer; Lenaerts, Caroline; Mathieu, Chantal; Boon, Louis; Kasran, Ahmad; Waer, Mark; Billiau, An D. 分享 收藏
Proteome analysis demonstrates profound alterations in human dendritic cell nature by TX527, an analogue of vitamin D Ferreira, Gabriela Bomfim; van Etten, Evelyne; Lage, Kasper; Hansen, Daniel Aaen; Moreau, Yves; Workman, Christopher T.; Waer, Mark; Verstuyf, Annemieke; Waelkens, Etienne; Overbergh, Lut; Mathieu, Chantal 分享 收藏
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