Inge Grundke‐Iqbal - Publications, H-index & Citations

Inge Grundke‐Iqbal

Institute for Basic Research in Developmental Disabilities

97H指数

530论文数

3.9W被引数

收录论文 125

发表时间

Inhibition of Protein Phosphatase-2A (PP2A) by I1PP2A Leads to Hyperphosphorylation of Tau, Neurodegeneration, and Cognitive Impairment in Rats

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2015-03-18

PREAI

Wang, Xiaochuan; Blanchard, Julie; Tung, Yunn Chyn; Grundke-Iqbal, Inge; Iqbal, Khalid

Cytoplasmic Retention of Protein Phosphatase 2A Inhibitor 2 (I2PP2A) Induces Alzheimer-like Abnormal Hyperphosphorylation of Tau

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-10-01

OAAI

Arif, Mohammad; Wei, Jianshe; Zhang, Qi; Liu, Fei; Basurto-Islas, Gustavo; Grundke-Iqbal, Inge; Iqbal, Khalid

Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies 在阿尔茨海默病和tau蛋白病的转基因小鼠模型中，靶向tau蛋白N端投射域的被动预防接种可降低tau蛋白病理并改善认知

JOURNAL OF NEURAL TRANSMISSION

IF4

2014-09-19

PREAI

Dai, Chun-ling; Chen, Xia; Kazim, Syed Faraz; Liu, Fei; Gong, Cheng-Xin; Grundke-Iqbal, Inge; Iqbal, Khalid

Tau pathology involves protein phosphatase 2A in Parkinsonism-dementia of Guam Tau病理学涉及关岛帕金森病-痴呆中的蛋白磷酸酶2A

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-01-06

OAAI

Arif, Mohammad; Kazim, Syed Faraz; Grundke-Iqbal, Inge; Garruto, Ralph M.; Iqbal, Khalid

Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection

ACTA NEUROPATHOLOGICA

IF9.3

2013-10-18

OAAI

Wang, Xiaochuan; Blanchard, Julie; Grundke-Iqbal, Inge; Wegiel, Jerzy; Deng, Han-Xiang; Siddique, Teepu; Iqbal, Khalid

Activation of Asparaginyl Endopeptidase Leads to Tau Hyperphosphorylation in Alzheimer Disease

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-06-01

111

OAAI

Basurto-Islas, Gustavo; Grundke-Iqbal, Inge; Tung, Yunn Chyn; Liu, Fei; Iqbal, Khalid

CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer's disease

NUCLEIC ACIDS RESEARCH

IF13.1

2013-01-22

OAAI

Jin, Nana; Qian, Wei; Yin, Xiaomin; Zhang, Lan; Iqbal, Khalid; Grundke-Iqbal, Inge; Gong, Cheng-Xin; Liu, Fei

Abnormal Hyperphosphorylation of Tau: Sites, Regulation, and Molecular Mechanism of Neurofibrillary Degeneration

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2012-12-27

477

PREAI

Wang, Jian-Zhi; Xia, Yi-Yuan; Grundke-Iqbal, Inge; Iqbal, Khalid

Dual-specificity Tyrosine Phosphorylation-regulated Kinase 1A (Dyrk1A) Modulates Serine/Arginine-rich Protein 55 (SRp55)-promoted Tau Exon 10 Inclusion

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-08-01

OAAI

Yin, Xiaomin; Jin, Nana; Gu, Jianlan; Shi, Jianhua; Zhou, Jianhua; Gong, Cheng-Xin; Iqbal, Khalid; Grundke-Iqbal, Inge; Liu, Fei

Regulation of alternative splicing of tau exon 10 by 9G8 and Dyrk1A

NEUROBIOLOGY OF AGING

IF3.5

2012-07-01

OAAI

Ding, Shaohong; Shi, Jianhua; Qian, Wei; Iqbal, Khalid; Grundke-Iqbal, Inge; Gong, Cheng-Xin; Liu, Fei

Diverse regulation of AKT and GSK-3β by O-GlcNAcylation in various types of cells 在各种类型的细胞中，通过o-glcnacylation对AKT和GSK-3β 的不同调节

FEBS LETTERS

IF3

2012-06-08

OAAI

Shi, Jianhua; Wu, Shiliang; Dai, Chun-ling; Li, Yi; Grundke-Iqbal, Inge; Iqbal, Khalid; Liu, Fei; Gong, Cheng-Xin

PROMISE AND FEASIBILITY OF INHIBITION OF TAU'S ABNORMAL HYPERPHOSPHORYLATION

NEUROBIOLOGY OF AGING

IF3.5

2012-05-01

PREAI

Iqbal, Khalid; Grundke-Iqbal, I.

Regional Comparison of the Neurogenic Effects of CNTF-Derived Peptides and Cerebrolysin in AβPP Transgenic Mice

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2011-12-12

OAAI

Rockenstein, Edward; Ubhi, Kiren; Doppler, Edith; Novak, Philipp; Moessler, Herbert; Li, Bin; Blanchard, Julie; Grundke-Iqbal, Inge; Iqbal, Khalid; Mante, Michael; Adame, Anthony; Crews, Leslie; Masliah, Eliezer

Rescue of Synaptic Failure and Alleviation of Learning and Memory Impairments in a Trisomic Mouse Model of Down Syndrome

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

IF3

2011-12-01

PREAI

Blanchard, Julie; Bolognin, Silvia; Chohan, Muhammad Omar; Rabe, Ausma; Iqbal, Khalid; Grundke-Iqbal, Inge

An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide

ACTA NEUROPATHOLOGICA

IF9.3

2011-11-15

OAAI

Bolognin, Silvia; Blanchard, Julie; Wang, Xiaochuan; Basurto-Islas, Gustavo; Tung, Yunn Chyn; Kohlbrenner, Erik; Grundke-Iqbal, Inge; Iqbal, Khalid

Opportunities and challenges in developing Alzheimer disease therapeutics

ACTA NEUROPATHOLOGICA

IF9.3

2011-09-30

PREAI

Iqbal, Khalid; Grundke-Iqbal, Inge

Enhancement of dentate gyrus neurogenesis, dendritic and synaptic plasticity and memory by a neurotrophic peptide

NEUROBIOLOGY OF AGING

IF3.5

2011-08-01

PREAI

Chohan, Muhammad Omar; Li, Bin; Blanchard, Julie; Tung, Yunn-Chyn; Heaney, Agnes T.; Rabe, Ausma; Iqbal, Khalid; Grundke-Iqbal, Inge

Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2PP2A/SET

FEBS LETTERS

IF3

2011-07-28

104

OAAI

Arnaud, Lisette; Chen, She; Liu, Fei; Li, Bin; Khatoon, Sabiha; Grundke-Iqbal, Inge; Iqbal, Khalid

Blood-Cerebrospinal Fluid Barrier Permeability in Alzheimer's Disease

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2011-07-08

OAAI

Chalbot, Sonia; Zetterberg, Henrik; Blennow, Kaj; Fladby, Tormod; Andreasen, Niels; Grundke-Iqbal, Inge; Iqbal, Khalid

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

JOURNAL OF PATHOLOGY

IF5.2

2011-05-19

425

OAAI

Liu, Ying; Liu, Fei; Grundke-Iqbal, Inge; Iqbal, Khalid; Gong, Cheng-Xin

研究方向