Masakazu Fukushima - Publications, H-index & Citations

Masakazu Fukushima

Vrije Universiteit Amsterdam

48H指数

362论文数

8.8K被引数

收录论文 67

发表时间

Targeted deletion of both thymidine phosphorylase and uridine phosphorylase and consequent disorders in mice

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Haraguchi, M; Tsujimoto, H; Fukushima, M; Higuchi, I; Kuribayashi, H; Utsumi, H; Nakayama, A; Hashizume, Y; Hirato, J; Yoshida, H; Hara, H; Hamano, S; Kawaguchi, H; Furukawa, T; Miyazono, K; Ishikawa, F; Toyoshima, H; Kaname, T; Komatsu, M; Chen, ZS; Gotanda, T; Tachiwada, T; Sumizawa, T; Miyadera, K; Osame, M; Yoshida, H; Noda, T; Yamada, Y; Akiyama, S

A simplified method for manufacturing RNAi therapeutics for local administration

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2019-06-01

PREAI

Ando, Hidenori; Abu Lila, Amr S.; Fukushima, Masakazu; Matsuoka, Rie; Shimizu, Taro; Okuhira, Keiichiro; Ishima, Yu; Huang, Cheng-Long; Wada, Hiromi; Ishida, Tatsuhiro

Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model

CANCER LETTERS

IF10.1

2017-08-01

OAAI

Abu Lila, Amr S.; Moriyoshi, Naoto; Fukushima, Masakazu; Huang, Cheng-Long; Wada, Hiromi; Ishida, Tatsuhiro

Development of novel antimetabolite, DFP-11207, with self-toxicity protection and its promising preclinical and clinical profiles

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Fukushima, Masakazu; Iizuka, Kenzo; Eshima, Kokoro; Zhang, Chung; Jin, Cheng; Eshima, Kiyoshi; Ajani, Jaffer

DFP-10825 IP delivery provides a new effective treatment option to peritoneal-disseminated cancers

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Jin, Cheng; Iizuka, Kenzo; Eshima, Kokoro; Fukushima, Masakazu; Ishida, Tatsuhiro; Huang, Cheng-Long; Wada, Hiromi; Eshima, Kiyoshi

An industrial method of manufacturing a novel RNAi anticancer drug, DFP-10825, for the treatment of peritoneal disseminated gastric cancer

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Ishida, Tatsuhiro; Ando, Hidenori; Fukushima, Masakazu; Huang, Cheng-Long; Wada, Hiromi

Co-administration of liposomal l-OHP and PEGylated TS shRNA-lipoplex: A novel approach to enhance anti-tumor efficacy and reduce the immunogenic response to RNAi molecules

JOURNAL OF CONTROLLED RELEASE

IF11.5

2017-06-01

PREAI

Alaaeldin, Eman; Abu Lila, Amr S.; Ando, Hidenori; Fukushima, Masakazu; Huang, Cheng-Long; Wada, Hiromi; Sarhan, Hatem A.; Khaled, Khaled A.; Ishida, Tatsuhiro

Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

IF5.8

2015-12-10

OAAI

Shimamoto, Yuji; Nukatsuka, Mamoru; Takechi, Teiji; Fukushima, Masakazu

Platelet-derived endothelial cell growth factor/thymidine phosphorylase inhibitor augments radiotherapeutic efficacy in experimental colorectal cancer

CANCER LETTERS

IF10.1

2012-05-01

PREAI

Miyatani, Tomohiko; Kurita, Nobuhiro; Utsunomiya, Tohru; Iwata, Takashi; Nishioka, Masanori; Yoshikawa, Kozo; Higashijima, Jun; Kashihara, Hideya; Takasu, Chie; Fukushima, Masakazu; Shimada, Mitsuo

Role of miR-19b and its target mRNAs in 5-fluorouracil resistance in colon cancer cells

JOURNAL OF GASTROENTEROLOGY

IF5.5

2012-03-01

PREAI

Kurokawa, Ken; Tanahashi, Toshihito; Iima, Tsutomu; Yamamoto, Yuta; Akaike, Yoko; Nishida, Kensei; Masuda, Kiyoshi; Kuwano, Yuki; Murakami, Yoshiki; Fukushima, Masakazu; Rokutan, Kazuhito

Thymidylate synthase (TS) gene expression in primary lung cancer patients: a large-scale study in Japanese population

ANNALS OF ONCOLOGY

IF65.4

2011-08-01

OAAI

Tanaka, F.; Wada, H.; Fukui, Y.; Fukushima, M.

A nucleoside anticancer drug, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine (TAS106), sensitizes cells to radiation by suppressing BRCA2 expression

MOLECULAR CANCER

IF33.9

2011-07-28

OAAI

Meike, Shunsuke; Yamamori, Tohru; Yasui, Hironobu; Eitaki, Masato; Matsuda, Akira; Morimatsu, Masami; Fukushima, Masakazu; Yamasaki, Yasundo; Inanami, Osamu

Induction chemotherapy for stage 4 gastric cancer and prognostic molecular markers

CANCER RESEARCH

IF16.6

2011-04-01

PREAI

Ueda, Shugo; Hattori, Kengo; Inoue, Yoshikage; Kadono, Kentaro; Yoshimura, Mio; Yoshida, Masahiro; Yoshitomi, Mami; Nomura, Akinari; Hashida, Hiroki; Terajima, Hiroaki; Ozaki, Nobuhiro; Fukushima, Masakazu

Thymidine phosphorylase in cancer cells stimulates human endothelial cell migration and invasion by the secretion of angiogenic factors

BRITISH JOURNAL OF CANCER

IF6.8

2011-03-08

OAAI

Bijnsdorp, I. V.; Capriotti, F.; Kruyt, F. A. E.; Losekoot, N.; Fukushima, M.; Griffioen, A. W.; Thijssen, V. L.; Peters, G. J.

Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line

FEBS JOURNAL

IF4.2

2010-09-28

OAAI

Sato, Akira; Naito, Tomoharu; Hiramoto, Akiko; Goda, Kazato; Omi, Takuya; Kitade, Yukio; Sasaki, Takuma; Matsuda, Akira; Fukushima, Masakazu; Wataya, Yusuke; Kim, Hye-Sook

Accumulation of thymidine-derived sugars in thymidine phosphorylase overexpressing cells

BIOCHEMICAL PHARMACOLOGY

IF5.6

2010-09-01

OAAI

Bijnsdorp, I. V.; Azijli, K.; Jansen, E. E.; Wamelink, M. M.; Jakobs, C.; Struys, E. A.; Fukushima, M.; Kruyt, F. A. E.; Peters, G. J.

Gimeracil sensitizes cells to radiation via inhibition of homologous recombination

RADIOTHERAPY AND ONCOLOGY

IF5.3

2010-08-01

PREAI

Takagi, Masaru; Sakata, Koh-ichi; Someya, Masanori; Tauchi, Hiroshi; Iijima, Kenta; Matsumoto, Yoshihisa; Torigoe, Toshihiko; Takahashi, Akari; Hareyama, Masato; Fukushima, Masakazu

Trifluorothymidine Resistance Is Associated with Decreased Thymidine Kinase and Equilibrative Nucleoside Transporter Expression or Increased Secretory Phospholipase A2

MOLECULAR CANCER THERAPEUTICS

IF5.5

2010-04-07

OAAI

Temmink, Olaf H.; Bijnsdorp, Irene V.; Prins, Henk-Jan; Losekoot, Nienke; Adema, Auke D.; Smid, Kees; Honeywell, Richard J.; Ylstra, Bauke; Eijk, Paul P.; Fukushima, Masakazu; Peters, Godefridus J.

Rapamycin enhances chemotherapy-induced cytotoxicity by inhibiting the expressions of TS and ERK in gastric cancer cells

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2010-03-23

OAAI

Shigematsu, Hideo; Yoshida, Kazuhiro; Sanada, Yuichi; Osada, Shinnji; Takahashi, Takao; Wada, Yoshiyuki; Konishi, Kazuo; Okada, Morihito; Fukushima, Masakazu

Differential activation of cell death and autophagy results in an increased cytotoxic potential for trifluorothymidine compared to 5-fluorouracil in colon cancer cells

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2010-01-08

PREAI

Bijnsdorp, Irene V.; Peters, Godefridus J.; Temmink, Olaf H.; Fukushima, Masakazu; Kruyt, Frank A.

研究方向