David Givol - Publications, H-index & Citations

David Givol

Weizmann Institute of Science

82H指数

329论文数

2.1W被引数

收录论文 33

发表时间

Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs

CELL CYCLE

IF3.4

2014-10-28

118

OAAI

Puca, Rosa; Nardinocchi, Lavinia; Porru, Manuela; Simon, Amos J.; Rechavi, Gideon; Leonetti, Carlo; Givol, David; D'Orazi, Gabriella

HIPK2-A therapeutical target to be (re)activated for tumor suppression Role in p53 activation and HIF-1α inhibition

CELL CYCLE

IF3.4

2014-10-27

PREAI

Nardinocchi, Lavinia; Puca, Rosa; Givol, David; D'Orazi, Gabriella

p53 reactivation The link to zinc

CELL CYCLE

IF3.4

2014-10-27

OAAI

D'Orazi, Gabriella; Givol, David

HIPK2 downregulates vimentin and inhibits breast cancer cell invasion

CANCER BIOLOGY & THERAPY

IF4.6

2014-10-27

OAAI

Nodale, Cristina; Sheffer, Michal; Jacob-Hirsch, Jasmine; Folgiero, Valentina; Falcioni, Rita; Aiello, Aurora; Garufi, Alessia; Rechavi, Gideon; Givol, David; D'Orazi, Gabriella

Zinc supplementation augments in vivo antitumor effect of chemotherapy by restoring p53 function

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2011-11-30

OAAI

Margalit, Ofer; Simon, Amos J.; Yakubov, Eduard; Puca, Rosa; Yosepovich, Ady; Avivi, Camila; Jacob-Hirsch, Jasmine; Gelernter, Ilana; Harmelin, Alon; Barshack, Iris; Rechavi, Gideon; D'Orazi, Gabriella; Givol, David; Amariglio, Ninette

Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/p53 apoptotic signaling in cancer cells

FEBS LETTERS

IF3

2010-09-16

OAAI

Nardinocchi, Lavinia; Puca, Rosa; Givol, David; D'Orazi, Gabriella

Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells

ONCOGENE

IF7.3

2010-05-31

143

PREAI

Puca, R.; Nardinocchi, L.; Givol, D.; D'Orazi, G.

Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2010-05-15

PREAI

Puca, Rosa; Nardinocchi, Lavinia; Starace, Giuseppe; Rechavi, Gideon; Sacchi, Ada; Givol, David; D'Orazi, Gabriella

HIPK2 modulates p53 activity towards pro-apoptotic transcription

MOLECULAR CANCER

IF33.9

2009-10-14

OAAI

Puca, Rosa; Nardinocchi, Lavinia; Sacchi, Ada; Rechavi, Gideon; Givol, David; D'Orazi, Gabriella

CD133-Positive hematopoietic stem cell Stemness genes contain many genes mutated or abnormally expressed in leukemia CD133-Positive造血干细胞干性基因在白血病中包含许多突变或异常表达的基因

Stem Cells

IF3.6

2009-01-02

OAAI

Toren, A; Bielorai, B; Jacob-Hirsch, J; Fisher, T; Kreiser, D; Moran, O; Zeligson, S; Givol, D; Yitzhaky, A; Itskovitz-Eldor, J; Kventsel, I; Rosenthal, E; Amariglio, N; Rechavi, G

Ruestoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc

EXPERIMENTAL CELL RESEARCH

IF3.5

2009-01-01

PREAI

Puca, Rosa; Nardinocchi, Lavinia; Bossi, Gianluca; Sacchi, Ada; Rechavi, Gideon; Givol, David; D'Orazi, Gabriella

PML, YAP, and p73 Are Components of a Proapoptotic Autoregulatory Feedback Loop PML，YAP和p73是促凋亡自动调节反馈回路的组成部分

MOLECULAR CELL

IF16.6

2008-12-01

236

OAAI

Lapi, Eleonora; Di Agostino, Silvia; Donzelli, Sara; Gal, Hilah; Domany, Eytan; Rechavi, Gideon; Pandolfi, Pier Paolo; Givol, David; Strano, Sabrina; Lu, Xin; Blandino, Giovanni

FGFR3 promotes synchondrosis closure and fusion of ossification centers through the MAPK pathway

HUMAN MOLECULAR GENETICS

IF3.2

2008-10-22

117

OAAI

Matsushita, Takehiko; Wilcox, William R.; Chan, Yuk Yu; Kawanami, Aya; Bukulmez, Huelya; Balmes, Gener; Krejci, Pavel; Mekikian, Pertchoui B.; Otani, Kazuyuki; Yamaura, Isakichi; Warman, Matthew L.; Givol, David; Murakami, Shunichi

Reversible dysfunction of wild-type p53 following homeodomain-interacting protein kinase-2 knockdown

CANCER RESEARCH

IF16.6

2008-05-15

OAAI

Puca, Rosa; Nardinocchi, Lavinia; Gal, Hilah; Rechavi, Gideon; Amariglio, Ninette; Domany, Eytan; Notterman, Daniel A.; Scarsella, Marco; Leonetti, Carlo; Sacchi, Ada; Blandino, Giovanni; Givol, David; D'Orazi, Gabriella

Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells

LEUKEMIA

IF13.4

2006-10-12

163

PREAI

Gal, H.; Amariglio, N.; Trakhtenbrot, L.; Jacob-Hirsh, J.; Margalit, O.; Avigdor, A.; Nagler, A.; Tavor, S.; Ein-Dor, L.; Lapidot, T.; Domany, E.; Rechavi, G.; Givol, D.

S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation

ONCOGENE

IF7.3

2006-01-30

PREAI

Lapi, E.; Iovino, A.; Fontemaggi, G.; Soliera, A. R.; Iacovelli, S.; Sacchi, A.; Rechavi, G.; Givol, D.; Blandino, G.; Strano, S.

The UVB-induced gene expression profile of human epidermis in vivo is different from that of cultured keratinocytes

ONCOGENE

IF7.3

2006-01-23

PREAI

Enk, CD; Jacob-Hirsch, J; Gal, H; Verbovetski, I; Amariglio, N; Mevorach, D; Ingber, A; Givol, D; Rechavi, G; Hochberg, M

Outcome signature genes in breast cancer: is there a unique set?

BREAST CANCER RESEARCH

IF5.6

2005-06-17

OAAI

Kela, I; Ein-Dor, L; Getz, G; Givol, D; Domany, E

Design principle of gene expression used by human stem cells: implication for pluripotency

FASEB JOURNAL

IF4.2

2004-10-21

OAAI

Golan-Mashiach, M; Dazard, JE; Gerecht-Nir, S; Amariglio, N; Fisher, T; Jacob-Hirsch, J; Bielorai, B; Osenberg, S; Barad, O; Getz, G; Toren, A; Rechavi, G; Itskovitz-Eldor, J; Domany, E; Givol, D

Hair growth induction by the tellurium immunomodulator AS101: association with delayed terminal differentiation of follicular keratinocytes and ras-dependent up-regulation of KGF expression

FASEB JOURNAL

IF4.2

2003-12-04

PREAI

Sredni, Benjamin; Gal, Rivka; Cohen, Ian J.; Dazard, Jean-Eudes; Givol, David; Gafter, Uzi; Motro, Benny; Eliyahu, Siona; Albeck, Michael; Lander, Harry M.; Kalechman, Yona

研究方向