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收藏分享 收藏 An orally available P1′-5-fluorinated Mpro inhibitor blocks SARS-CoV-2 replication without booster and exhibits high genetic barrier
Higashi-Kuwata, Nobuyo; Bulut, Haydar; Hayashi, Hironori; Tsuji, Kohei; Ogata-Aoki, Hiromi; Kiso, Maki; Takamune, Nobutoki; Kishimoto, Naoki; Hattori, Shin-ichiro; Ishii, Takahiro; Kobayakawa, Takuya; Nakano, Kenta; Shimizu, Yukiko; Das, Debananda; Saruwatari, Junji; Hasegawa, Kazuya; Murayama, Kazutaka; Sukenaga, Yoshikazu; Takamatsu, Yuki; Yoshimura, Kazuhisa; Aoki, Manabu; Furusawa, Yuri; Okamura, Tadashi; Yamayoshi, Seiya; Kawaoka, Yoshihiro; Misumi, Shogo; Tamamura, Hirokazu; Mitsuya, Hiroaki 分享 收藏 Induction of IGHV3-53 public antibodies with broadly neutralising activity against SARS-CoV-2 including Omicron subvariants in a Delta breakthrough infection caseKuwata, Takeo; Kaku, Yu; Biswas, Shashwata; Matsumoto, Kaho; Shimizu, Mikiko; Kawanami, Yoko; Uraki, Ryuta; Okazaki, Kyo; Minami, Rumi; Nagasaki, Yoji; Nagashima, Mami; Yoshida, Isao; Sadamasu, Kenji; Yoshimura, Kazuhisa; Ito, Mutsumi; Kiso, Maki; Yamayoshi, Seiya; Imai, Masaki; Ikeda, Terumasa; Sato, Kei; Toyoda, Mako; Ueno, Takamasa; Inoue, Takako; Tanaka, Yasuhito; Kimura, Kanako Tarakado; Hashiguchi, Takao; Sugita, Yukihiko; Noda, Takeshi; Morioka, Hiroshi; Kawaoka, Yoshihiro; Matsushita, Shuzo 分享 收藏 Virological characteristics of the SARS-CoV-2 XEC variantKaku, Yu; Okumura, Kaho; Kawakubo, Shusuke; Uriu, Keiya; Chen, Luo; Kosugi, Yusuke; Uwamino, Yoshifumi; Begum, M. S. T. Monira; Leong, Sharee; Ikeda, Terumasa; Sadamasu, Kenji; Asakura, Hiroyuki; Nagashima, Mami; Yoshimura, Kazuhisa; Ito, Jumpei; See, Kei Sato 分享 收藏 A heterocyclic compound inhibits viral release by inducing cell surface BST2/Tetherin/CD317/HM1.24Nyame, Perpetual; Togami, Akihiro; Yoshida, Tomofumi; Masunaga, Takuya; Begum, Monira; Terasawa, Hiromi; Monde, Nami; Tahara, Yurika; Tanaka, Reiko; Tanaka, Yuetsu; Appiah-Kubi, Joyce; Amesimeku, Wright Andrews Ofotsu; Hossain, Md Jakir; Otsuka, Masami; Yoshimura, Kazuhisa; Ikeda, Terumasa; Sawa, Tomohiro; Satou, Yorifumi; Fujita, Mikako; Maeda, Yosuke; Tateishi, Hiroshi; Monde, Kazuaki 分享 收藏 A micro-disc-based multiplex method for monitoring emerging SARS-CoV-2 variants using the molecular diagnostic tool Intelli-OVIHossain, Md Belal; Uchiyama, Yoshikazu; Rajib, Samiul Alam; Rahman, Akhinur; Takatori, Mitsuyoshi; Tan, Benjy Jek Yang; Sugata, Kenji; Nagashima, Mami; Kawakami, Mamiyo; Ito, Hitoshi; Kumagai, Ryota; Sadamasu, Kenji; Ogi, Yasuhiro; Kawaguchi, Tatsuya; Tamura, Tomokazu; Fukuhara, Takasuke; Ono, Masahiro; Yoshimura, Kazuhisa; Satou, Yorifumi 分享 收藏 分享 收藏 Virological characteristics of the SARS-CoV-2 KP.2 variantKaku, Yu; Uriu, Keiya; Kosugi, Yusuke; Okumura, Kaho; Yamasoba, Daichi; Uwamino, Yoshifumi; Kuramochi, Jin; Sadamasu, Kenji; Yoshimura, Kazuhisa; Asakura, Hiroyuki; Nagashima, Mami; Ito, Jumpei; Sato, Kei 分享 收藏 Virological characteristics of the SARS-CoV-2 Omicron XBB.1.5 variantTamura, Tomokazu; Irie, Takashi; Deguchi, Sayaka; Yajima, Hisano; Tsuda, Masumi; Nasser, Hesham; Mizuma, Keita; Plianchaisuk, Arnon; Suzuki, Saori; Uriu, Keiya; Begum, Mst Monira; Shimizu, Ryo; Jonathan, Michael; Suzuki, Rigel; Kondo, Takashi; Ito, Hayato; Kamiyama, Akifumi; Yoshimatsu, Kumiko; Shofa, Maya; Hashimoto, Rina; Anraku, Yuki; Kimura, Kanako Terakado; Kita, Shunsuke; Sasaki, Jiei; Sasaki-Tabata, Kaori; Maenaka, Katsumi; Nao, Naganori; Wang, Lei; Oda, Yoshitaka; Sawa, Hirofumi; Kawabata, Ryoko; Watanabe, Yukio; Sakamoto, Ayaka; Yasuhara, Naoko; Suzuki, Tateki; Nakajima, Yukari; Ferdous, Zannatul; Shishido, Kenji; Mugita, Yuka; Takahashi, Otowa; Ichihara, Kimiko; Kaku, Yu; Misawa, Naoko; Guo, Ziyi; Hinay, Alfredo, Jr.; Kosugi, Yusuke; Fujita, Shigeru; Tolentino, Jarel M.; Chen, Luo; Pan, Lin; Suganami, Mai; Chiba, Mika; Yoshimura, Ryo; Yasuda, Kyoko; Iida, Keiko; Ohsumi, Naomi; Strange, Adam P.; Shibatani, Yuki; Nishiuchi, Tomoko; Tanaka, Shiho; Putri, Olivia; Joas, Gustav; Kim, Yoonjin; Yamasoba, Daichi; Yoshimura, Kazuhisa; Sadamasu, Kenji; Nagashima, Mami; Asakura, Hiroyuki; Yoshida, Isao; Nakagawa, So; Takaori-Kondo, Akifumi; Shirakawa, Kotaro; Nagata, Kayoko; Nomura, Ryosuke; Horisawa, Yoshihito; Tashiro, Yusuke; Kawai, Yugo; Ueno, Takamasa; Motozono, Chihiro; Toyoda, Mako; Ikeda, Terumasa; Saito, Akatsuki; Matsuno, Keita; Ito, Jumpei; Tanaka, Shinya; Sato, Kei; Hashiguchi, Takao; Takayama, Kazuo; Fukuhara, Takasuke 分享 收藏 Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristicsKimura, Izumi; Yamasoba, Daichi; Nasser, Hesham; Ito, Hayato; Zahradnik, Jiri; Wu, Jiaqi; Fujita, Shigeru; Uriu, Keiya; Sasaki, Jiei; Tamura, Tomokazu; Suzuki, Rigel; Deguchi, Sayaka; Plianchaisuk, Arnon; Yoshimatsu, Kumiko; Kazuma, Yasuhiro; Mitoma, Shuya; Schreiber, Gideon; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Takaori-Kondo, Akifumi; Ito, Jumpei; Shirakawa, Kotaro; Takayama, Kazuo; Irie, Takashi; Hashiguchi, Takao; Nakagawa, So; Fukuhara, Takasuke; Saito, Akatsuki; Ikeda, Terumasa; Sato, Kei 分享 收藏 Virological outcomes of various first-line ART regimens in patients harbouring HIV-1 E157Q integrase polymorphism: a multicentre retrospective studyUno, Shunsuke; Gatanaga, Hiroyuki; Hayashida, Tsunefusa; Imahashi, Mayumi; Minami, Rumi; Koga, Michiko; Samukawa, Sei; Watanabe, Dai; Fujii, Teruhisa; Tateyama, Masao; Nakamura, Hideta; Matsushita, Shuzo; Yoshino, Yusuke; Endo, Tomoyuki; Horiba, Masahide; Taniguchi, Toshibumi; Moro, Hiroshi; Igari, Hidetoshi; Yoshida, Shigeru; Teshima, Takanori; Nakajima, Hideaki; Nishizawa, Masako; Yokomaku, Yoshiyuki; Iwatani, Yasumasa; Hachiya, Atsuko; Kato, Shingo; Hasegawa, Naoki; Yoshimura, Kazuhisa; Sugiura, Wataru; Kikuchi, Tadashi 分享 收藏 Antiviral efficacy of the SARS-CoV-2 XBB breakthrough infection sera against omicron subvariants including EG.5Kaku, Yu; Kosugi, Yusuke; Uriu, Keiya; Ito, Jumpei; Hinay, Alfredo A.; Kuramochi, Jin; Sadamasu, Kenji; Yoshimura, Kazuhisa; Asakura, Hiroyuki; Nagashima, Mami; Sato, Kei 分享 收藏 分享 收藏 Synthesis and evaluation of DAG-lactone derivatives with HIV-1 latency reversing activityIshii, Takahiro; Kobayakawa, Takuya; Matsuda, Kouki; Tsuji, Kohei; Ohashi, Nami; Nakahata, Shingo; Noborio, Airi; Yoshimura, Kazuhisa; Mitsuya, Hiroaki; Maeda, Kenji; Tamamura, Hirokazu 分享 收藏 Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariantsTamura, Tomokazu; Ito, Jumpei; Uriu, Keiya; Zahradnik, Jiri; Kida, Izumi; Anraku, Yuki; Nasser, Hesham; Shofa, Maya; Oda, Yoshitaka; Lytras, Spyros; Nao, Naganori; Itakura, Yukari; Deguchi, Sayaka; Suzuki, Rigel; Wang, Lei; Begum, M. S. T. Monira; Kita, Shunsuke; Yajima, Hisano; Sasaki, Jiei; Sasaki-Tabata, Kaori; Shimizu, Ryo; Tsuda, Masumi; Kosugi, Yusuke; Fujita, Shigeru; Pan, Lin; Sauter, Daniel; Yoshimatsu, Kumiko; Suzuki, Saori; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Yamamoto, Yuki; Nagamoto, Tetsuharu; Schreiber, Gideon; Maenaka, Katsumi; Hashiguchi, Takao; Ikeda, Terumasa; Fukuhara, Takasuke; Saito, Akatsuki; Tanaka, Shinya; Matsuno, Keita; Takayama, Kazuo; Sato, Kei 分享 收藏 Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variantIto, Jumpei; Suzuki, Rigel; Uriu, Keiya; Itakura, Yukari; Zahradnik, Jiri; Kimura, Kanako Terakado; Deguchi, Sayaka; Wang, Lei; Lytras, Spyros; Tamura, Tomokazu; Kida, Izumi; Nasser, Hesham; Shofa, Maya; Begum, Mst Monira; Tsuda, Masumi; Oda, Yoshitaka; Suzuki, Tateki; Sasaki, Jiei; Sasaki-Tabata, Kaori; Fujita, Shigeru; Yoshimatsu, Kumiko; Ito, Hayato; Nao, Naganori; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Yamamoto, Yuki; Nagamoto, Tetsuharu; Kuramochi, Jin; Schreiber, Gideon; Saito, Akatsuki; Matsuno, Keita; Takayama, Kazuo; Hashiguchi, Takao; Tanaka, Shinya; Fukuhara, Takasuke; Ikeda, Terumasa; Sato, Kei; Suzuki, Saori; Kato, Marie; Ferdous, Zannatul; Mouri, Hiromi; Shishido, Kenji; Misawa, Naoko; Kimura, Izumi; Kosugi, Yusuke; Lin, Pan; Suganami, Mai; Chiba, Mika; Yoshimura, Ryo; Yasuda, Kyoko; Iida, Keiko; Ohsumi, Naomi P.; Strange, Adam; Sauter, Daniel; Nakagawa, So; Wu, Jiaqi; Watanabe, Yukio; Sakamoto, Ayaka; Yasuhara, Naoko; Nakajima, Yukari; Yajima, Hisano; Shirakawa, Kotaro; Takaori-Kondo, Akifumi; Nagata, Kayoko; Kazuma, Yasuhiro; Nomura, Ryosuke; Horisawa, Yoshihito; Tashiro, Yusuke; Kawa, Yugo; Irie, Takashi; Kawabata, Ryoko; Shimizu, Ryo; Takahashi, Otowa; Ichihara, Kimiko; Motozono, Chihiro; Toyoda, Mako; Ueno, Takamasa; Shibatani, Yuki; Nishiuchi, Tomoko 分享 收藏 Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2Higashi-Kuwata, Nobuyo; Tsuji, Kohei; Hayashi, Hironori; Bulut, Haydar; Kiso, Maki; Imai, Masaki; Ogata-Aoki, Hiromi; Ishii, Takahiro; Kobayakawa, Takuya; Nakano, Kenta; Takamune, Nobutoki; Kishimoto, Naoki; Hattori, Shin-ichiro; Das, Debananda; Uemura, Yukari; Shimizu, Yosuke; Aoki, Manabu; Hasegawa, Kazuya; Suzuki, Satoshi; Nishiyama, Akie; Saruwatari, Junji; Shimizu, Yukiko; Sukenaga, Yoshikazu; Takamatsu, Yuki; Tsuchiya, Kiyoto; Maeda, Kenji; Yoshimura, Kazuhisa; Iida, Shun; Ozono, Seiya; Suzuki, Tadaki; Okamura, Tadashi; Misumi, Shogo; Kawaoka, Yoshihiro; Tamamura, Hirokazu; Mitsuya, Hiroaki 分享 收藏 Transmission of COVID-19 in Nightlife, Household, and Health Care Settings in Tokyo, Japan, in 2020Imamura, Takeaki; Watanabe, Aika; Serizawa, Yusuke; Nakashita, Manami; Saito, Mayuko; Okada, Mayu; Ogawa, Asamoe; Tabei, Yukiko; Soumura, Yoshiko; Nadaoka, Yoko; Nakatsubo, Naoki; Chiba, Takashi; Sadamasu, Kenji; Yoshimura, Kazuhisa; Noda, Yoshihiro; Iwashita, Yuko; Ishimaru, Yuji; Seki, Naomi; Otani, Kanako; Imamura, Tadatsugu; Griffith, Matthew Myers; DeToy, Kelly; Suzuki, Motoi; Yoshida, Michihiko; Tanaka, Atsuko; Yauchi, Mariko; Shimada, Tomoe; Oshitani, Hitoshi 分享 收藏 分享 收藏 
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