Ruth E. Westenbroek - Publications, H-index & Citations

Ruth E. Westenbroek

University of Washington

59H指数

148论文数

1.4W被引数

收录论文 54

发表时间

Anchored PKA synchronizes adrenergic phosphoregulation of cardiac Cav1.2 channels

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-09-01

OAAI

Wang, Lipeng; Chen, Yi; Li, Jin; Westenbroek, Ruth; Philyaw, Travis; Zheng, Ning; Scott, John D.; Liu, Qinghang; Catterall, William A.

William A. Catterall (1946-2024)

NEURON

IF15

2024-06-01

OAAI

Scheuer, Todd; Westenbroek, Ruth; Zheng, Ning; Kalume, Franck; Vien, Thuy N.; Payandeh, Jian; DeCaen, Paul G.

The serine hydrolase ABHD6 controls survival and thermally induced seizures in a mouse model of Dravet syndrome

NEUROBIOLOGY OF DISEASE

IF5.6

2023-05-01

OAAI

Westenbroek, Ruth; Kaplan, Joshua; Viray, Katie; Stella, Nephi

The AKAP Cypher/Zasp contributes to β-adrenergic/PKA stimulation of cardiac Cav1.2 calcium channels

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2018-05-09

OAAI

Yu, Haijie; Yuan, Can; Westenbroek, Ruth E.; Catterall, William A.

Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome 大麻二酚可减轻Dravet综合征小鼠模型的癫痫发作和社会缺陷

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-10-02

297

OAAI

Kaplan, Joshua S.; Stella, Nephi; Catterall, William A.; Westenbroek, Ruth E.

Loss of β-adrenergic-stimulated phosphorylation of CaV1.2 channels on Ser1700 leads to heart failure Ser1700上 β-肾上腺素能刺激的CaV1.2通道磷酸化的丧失导致心力衰竭

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-11-18

OAAI

Yang, Linghai; Dai, Dao-Fu; Yuan, Can; Westenbroek, Ruth E.; Yu, Haijie; West, Nastassya; de la Iglesia, Horacio O.; Catterall, William A.

KATP channel gain-of-function leads to increased myocardial L-type Ca2+ current and contractility in Cantu syndrome

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-05-31

OAAI

Levin, Mark D.; Singh, Gautam K.; Zhang, Hai Xia; Uchida, Keita; Kozel, Beth A.; Stein, Phyllis K.; Kovacs, Atilla; Westenbroek, Ruth E.; Catterall, William A.; Grange, Dorothy Katherine; Nichols, Colin G.

Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor S1928上Cav1.2的磷酸化使L型Ca2通道与 β2肾上腺素能受体分离

EMBO JOURNAL

IF8.3

2016-04-21

OAAI

Patriarchi, Tommaso; Qian, Hai; Di Biase, Valentina; Malik, Zulfiquar A.; Chowdhury, Dhrubajyoti; Price, Jennifer L.; Hammes, Erik A.; Buonarati, Olivia R.; Westenbroek, Ruth E.; Catterall, William A.; Hofmann, Franz; Xiang, Yang K.; Murphy, Geoffrey G.; Chen, Chao-Ye; Navedo, Manuel F.; Hell, Johannes W.

Dissecting the phenotypes of Dravet syndrome by gene deletion

BRAIN

IF11.7

2015-05-27

104

OAAI

Rubinstein, Moran; Han, Sung; Tai, Chao; Westenbroek, Ruth E.; Hunker, Avery; Scheuer, Todd; Catterall, William A.

Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome

NEUROBIOLOGY OF DISEASE

IF5.6

2015-05-01

OAAI

Kalume, Franck; Oakley, John C.; Westenbroek, Ruth E.; Gile, Jennifer; de la Iglesia, Horacio O.; Scheuer, Todd; Catterall, William A.

Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome

NEUROBIOLOGY OF DISEASE

IF5.6

2015-01-01

OAAI

Rubinstein, Moran; Westenbroek, Ruth E.; Yu, Frank H.; Jones, Christina J.; Scheuer, Todd; Catterall, William A.

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome

CHANNELS

IF3.2

2014-11-03

OAAI

Cheah, Christine S.; Westenbroek, Ruth E.; Roden, William H.; Kalume, Franck; Oakley, John C.; Jansen, Laura A.; Catterall, William A.

Basal and β-adrenergic regulation of the cardiac calcium channel CaV1.2 requires phosphorylation of serine 1700

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-11-03

OAAI

Fu, Ying; Westenbroek, Ruth E.; Scheuer, Todd; Catterall, William A.

Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-07-14

200

OAAI

Tai, Chao; Abe, Yasuyuki; Westenbroek, Ruth E.; Scheuer, Todd; Catterall, William A.

PDE4B mediates local feedback regulation of β1-adrenergic cAMP signaling in a sarcolemmal compartment of cardiac myocytes

JOURNAL OF CELL SCIENCE

IF3.6

2014-01-01

OAAI

Mika, Delphine; Richter, Wito; Westenbroek, Ruth E.; Catterall, William A.; Conti, Marco

Phosphorylation sites required for regulation of cardiac calcium channels in the fight-or-flight response

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-11-11

OAAI

Fu, Ying; Westenbroek, Ruth E.; Scheuer, Todd; Catterall, William A.

Localization of sodium channel subtypes in mouse ventricular myocytes using quantitative immunocytochemistry

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2013-11-01

OAAI

Westenbroek, Ruth E.; Bischoff, Sebastian; Fu, Ying; Maier, Sebastian K. G.; Catterall, William A.; Scheuer, Todd

Apolipoprotein CIII hyperactivates β cell CaV1 channels through SR-BI/β1 integrin-dependent coactivation of PKA and Src

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2013-08-15

OAAI

Shi, Yue; Yang, Guang; Yu, Jia; Yu, Lina; Westenbroek, Ruth; Catterall, William A.; Juntti-Berggren, Lisa; Berggren, Per-Olof; Yang, Shao-Nian

Differential regulation of cardiac excitation-contraction coupling by cAMP phosphodiesterase subtypes

CARDIOVASCULAR RESEARCH

IF13.3

2013-08-09

OAAI

Mika, Delphine; Bobin, Pierre; Pomerance, Martine; Lechene, Patrick; Westenbroek, Ruth E.; Catterall, William A.; Vandecasteele, Gregoire; Leroy, Jerome; Fischmeister, Rodolphe

Distribution and function of sodium channel subtypes in human atrial myocardium

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2013-08-01

OAAI

Kaufmann, Susann G.; Westenbroek, Ruth E.; Maass, Alexander H.; Lange, Volkmar; Renner, Andre; Wischmeyer, Erhard; Bonz, Andreas; Muck, Jenny; Ertl, Georg; Catterall, William A.; Scheuer, Todd; Maier, Sebastian K. G.

研究方向