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Discovery and Model-Informed Drug Development of a Controlled-Release Formulation of Nonracemic Amisulpride that Reduces Plasma Exposure but Achieves Pharmacodynamic Bioequivalence in the Brain Hopkins, Seth C.; Toongsuwan, Siriporn; Corriveau, Taryn J.; Watanabe, Takao; Tsushima, Yuki; Asada, Takumi; Lew, Robert; Shi, Lei; Zann, Vanessa; Snowden, Thomas J.; van Der Graaf, Piet H.; Darpo, Borje; Searle, Graham E.; Rabiner, Eugenii A.; Wilding, Ian; Szabo, Steven T.; Galluppi, Gerald R.; Koblan, Kenneth S. 分享 收藏
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A multicenter, double-blind, placebo-controlled, randomized, Phase 1b crossover trial comparing two doses of ulotaront with placebo in the treatment of narcolepsy-cataplexy Szabo, Steven T.; Hopkins, Seth C.; Lew, Robert; Loebel, Antony; Roth, Thomas; Koblan, Kenneth S. 分享 收藏
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SEP-363856, a Novel Psychotropic Agent with a Unique, Non-D2 Receptor Mechanism of Action SEP-363856,一种具有独特Non-D2受体作用机制的新型精神药物 Dedic, Nina; Jones, Philip G.; Hopkins, Seth C.; Lew, Robert; Shao, Liming; Campbell, John E.; Spear, Kerry L.; Large, Thomas H.; Campbell, Una C.; Hanania, Taleen; Leahy, Emer; Koblan, Kenneth S. 分享 收藏
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Design, Synthesis, and Structure-Activity Relationships of Novel Bicyclic Azole-amines as Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5 Burdi, Douglas F.; Hunt, Rachel; Fan, Lei; Hu, Tao; Wang, Jun; Guo, Zihong; Huang, Zhiqiang; Wu, Chengde; Hardy, Larry; Detheux, Michel; Orsini, Michael A.; Quinton, Maria S.; Lew, Robert; Spear, Kerry 分享 收藏
Are drug-eluting stents indicated in large coronary arteries? Insights from a multi-centre percutaneous coronary intervention registry Yan, Bryan P.; Ajani, Andrew E.; New, Gishel; Duffy, Stephen J.; Farouque, Omar; Shaw, James; Sebastian, Martin; Lew, Robert; Brennan, Angela; Andrianopoulos, Nick; Reid, Chris; Clark, David J. 分享 收藏
Outcomes after percutaneous coronary intervention in contemporary Australian practice: insights from a large multicentre registry Ajani, Andrew E.; Reid, Christopher M.; Duffy, Stephen J.; Andrianopoulos, Nick; Lefkovits, Jeffrey; Black, Alexander; New, Gishel; Lew, Robert; Shaw, James A.; Yan, Bryan P.; Gurvitch, Ronen; Al-Fiadh, Ali; Brennan, Angela L.; Clark, David J. 分享 收藏
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Repeat intracoronary radiation for recurrent in-stent restenosis in patients who failed intracoronary radiation 重复冠状动脉内放射治疗失败的患者复发性支架内再狭窄 Waksman, R; Lew, R; Ajani, AE; Pichard, AD; Satler, LF; Kent, KM; Chan, R; White, RL; Suddath, WO; Pinnow, E; Torguson, R; Dilcher, C; Wolfram, R; Lindsay, J 分享 收藏
Preliminary assessment of extrastriatal dopamine D-2 receptor binding in the rodent and nonhuman primate brains using the high affinity radioligand, 18F-fallypride Mukherjee, J; Yang, ZY; Brown, T; Lew, R; Wernick, M; Ouyang, XH; Yasillo, N; Chen, CT; Mintzer, R; Cooper, M 分享 收藏
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