未登录 PepSeA: Peptide Sequence Alignment and Visualization Tools to Enable Lead Optimization Baylon, Javier L.; Ursu, Oleg; Muzdalo, Anja; Wassermann, Anne Mai; Adams, Gregory L.; Spale, Martin; Mejzlik, Petr; Gromek, Anna; Pisarenko, Viktor; Hancharyk, Dzianis; Jenkins, Esteban; Bednar, David; Chang, Charlie; Clarova, Kamila; Glick, Meir; Bitton, Danny A. 分享 收藏
High-Throughput Screen for Inhibitors of Klebsiella pneumoniae Virulence Using a Tetrahymena pyriformis Co-Culture Surrogate Host Model Woods, Angela L.; Parker, David; Glick, Meir M.; Peng, Yunshan; Lenoir, Francois; Mulligan, Evan; Yu, Vincent; Piizzi, Grazia; Lister, Troy; Lilly, Maria-Dawn; Dzink-Fox, Joann; Jansen, Johanna M.; Ryder, Neil S.; Dean, Charles R.; Smith, Thomas M. 分享 收藏
Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer LaMarche, Matthew J.; Acker, Michael; Argintaru, Andreea; Bauer, Daniel; Boisclair, Julie; Chan, Homan; Chen, Christine Hiu-Tung; Chen, Ying-Nan; Chen, Zhouliang; Deng, Zhan; Dore, Michael; Dunstan, David; Fan, Jianmei; Fekkes, Peter; Firestone, Brant; Fodor, Michelle; Garcia-Fortanet, Jorge; Fortin, Pascal D.; Fridrich, Cary; Giraldes, John; Glick, Meir; Grunenfelder, Denise; Hao, Huia-Xiang; Hentemann, Martin; Ho, Samuel; Jouk, Andriana; Kang, Zhao B.; Karki, Rajesh; Kato, Mitsunori; Keen, Nick; Koenig, Robert; LaBonte, Laura R.; Larrow, Jay; Liu, Gang; Liu, Shumei; Majumdar, Dyuti; Mathieu, Simon; Meyer, Matthew J.; Mohseni, Morvarid; Ntaganda, Rukundo; Palermo, Mark; Perez, Lawrence; Pu, Minying; Ramsey, Timothy; Reilly, John; Sarver, Patrick; Sellers, William R.; Sendzik, Martin; Shultz, Michael D.; Slisz, Joanna; Slocum, Kelly; Smith, Troy; Spence, Stanley; Stams, Travis; Straub, Christopher; Tamez, Victoriano, Jr.; Toure, Bakary-Barry; Towler, Christopher; Wang, Ping; Wang, Hongyun; Williams, Sarah L.; Yang, Fan; Yu, Bing; Zhang, Ji-Hu; Zhu, Suzanne 分享 收藏
A mass spectrometry-based proteome map of drug action in lung cancer cell lines (Jul, 10.1038/s41589-020-0572-3, 2020) Ruprecht, Benjamin; Di Bernardo, Julie; Wang, Zhao; Mo, Xuan; Ursu, Oleg; Christopher, Matthew; Fernandez, Rafael B.; Zheng, Li; Dill, Brian D.; Wang, Huijun; Xu, Yuting; Liaw, Andy; Mortison, Jonathan D.; Siriwardana, Nirodhini; Andresen, Brian; Glick, Meir; Tata, James R.; Kutilek, Victoria; Cornella-Taracido, Ivan; Chi, An 分享 收藏
A mass spectrometry-based proteome map of drug action in lung cancer cell lines Ruprecht, Benjamin; Di Bernardo, Julie; Wang, Zhao; Mo, Xuan; Ursu, Oleg; Christopher, Matthew; Fernandez, Rafael B.; Zheng, Li; Dill, Brian D.; Wang, Huijun; Xu, Yuting; Liaw, Andy; Mortison, Jonathan D.; Siriwardana, Nirodhini; Andresen, Brian; Glick, Meir; Tata, James R.; Kutilek, Victoria; Cornella-Taracido, Ivan; Chi, An 分享 收藏
Experimental Error, Kurtosis, Activity Cliffs, and Methodology: What Limits the Predictivity of Quantitative Structure-Activity Relationship Models? Sheridan, Robert P.; Karnachi, Prabha; Tudor, Matthew; Xu, Yuting; Liaw, Andy; Shah, Falgun; Cheng, Alan C.; Joshi, Elizabeth; Glick, Meir; Alvarez, Juan 分享 收藏
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Simultaneous inhibition of SHP2 phosphatase at two allosteric sites Fodor, Michelle; Price, Edmund; Wang, Ping; Lu, Hengyu; Argintaru, Andreea; Chen, Zhouliang; Glick, Meir; Hao, Huai-Xiang; Kato, Mitsunori; Koenig, Robert; LaRochelle, Jonathan R.; Liu, Gang; McNeill, Eric; Majumdar, Dyuti; Nishiguchi, Gisele; Perez, Lawrence; Paris, Greg; Quinn, Christopher; Ramsey, Timothy; Sendzik, Martin; Shultz, Michael; Williams, Sarah; Stams, Travis; Blacklow, Stephen C.; LaMarche, Matthew J.; Acker, Michael G. 分享 收藏
Dual Allosteric Inhibition of SHP2 Phosphatase Fodor, Michelle; Price, Edmund; Wang, Ping; Lu, Hengyu; Argintaru, Andreea; Chen, Zhouliang; Glick, Meir; Hao, Huai-Xiang; Kato, Mitsunori; Koenig, Robert; LaRochelle, Jonathan R.; Liu, Gang; McNeill, Eric; Majumdar, Dyuti; Nishiguchi, Gisele A.; Perez, Lawrence B.; Paris, Gregory; Quinn, Christopher M.; Ramsey, Timothy; Sendzik, Martin; Shultz, Michael David; Williams, Sarah L.; Stams, Travis; Blacklow, Stephen C.; Acker, Michael G.; LaMarche, Matthew J. 分享 收藏
CHEMGENIE: integration of chemogenomics data for applications in chemical biology Kutchukian, Peter S.; Change, Charlie; Fox, Sean J.; Cook, Erica; Barnard, Richard; Tellers, David; Wang, Huijun; Pertusi, Dante; Glick, Meir; Sheridan, Robert P.; Wallace, Lain M.; Wassermann, Anne Mai 分享 收藏
Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase Maria, John P. Santa, Jr.; Park, Yumi; Yang, Lihu; Murgolo, Nicholas; Altman, Michael D.; Zuck, Paul; Adam, Greg; Chamberlin, Chad; Saradjian, Peter; Dandliker, Peter; Boshoff, Helena I. M.; Barry, Clifton E., III; Garlisi, Charles; Olsen, David B.; Young, Katherine; Glick, Meir; Nickbarg, Elliott; Kutchukian, Peter S. 分享 收藏
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Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC Piizzi, Grazia; Parker, David T.; Peng, Yunshan; Dobler, Markus; Patnaik, Anup; Wattanasin, Som; Liu, Eugene; Lenoir, Francois; Nunez, Jill; Kerrigan, John; McKenney, David; Osborne, Colin; Yu, Donghui; Lanieri, Leanne; Bojkovic, Jade; Dzink-Fox, Joann; Lilly, Maria-Dawn; Sprague, Elizabeth R.; Lu, Yipin; Wang, Hongming; Ranjitkar, Srijan; Xie, Lili; Wang, Bing; Glick, Meir; Hamann, Lawrence G.; Tommasi, Ruben; Yang, Xia; Dean, Charles R. 分享 收藏
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Construction of a 3D-shaped, natural product like fragment library by fragmentation and diversification of natural products 通过天然产物的片段化和多样化构建3d形状的天然产物样片段库 Prescher, Horst; Koch, Guido; Schuhmann, Tim; Ertl, Peter; Bussenault, Alex; Glick, Meir; Dix, Ina; Petersen, Frank; Lizos, Dimitrios E. 分享 收藏
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Potent, Selective, and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo Honda, Ayako; Harrington, Edmund; Cornella-Taracido, Ivan; Furet, Pascal; Knapp, Mark S.; Glick, Meir; Triantafellow, Ellen; Dowdle, William E.; Wiedershain, Dmitri; Maniara, Wieslawa; Moore, Christine; Finan, Peter M.; Hamann, Lawrence G.; Firestone, Brant; Murphy, Leon O.; Keaney, Erin P. 分享 收藏
Dark chemical matter as a promising starting point for drug lead discovery Wassermann, Anne Mai; Lounkine, Eugen; Hoepfner, Dominic; Le Goff, Gaelle; King, Frederick J.; Studer, Christian; Peltier, John M.; Grippo, Melissa L.; Prindle, Vivian; Tao, Jianshi; Schuffenhauer, Ansgar; Wallace, Iain M.; Chen, Shanni; Krastel, Philipp; Cobos-Correa, Amanda; Parker, Christian N.; Davies, John W.; Glick, Meir 分享 收藏
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