未登录Deregulation of the p19/CDK4/CDK6 axis in Jak2V617F megakaryocytes accelerates the development of myelofibrosis
Duparc, Helene; Muller, Delphine; Gilles, Laure; Chedeville, Agathe L.; El Khoury, Mira; Guignard, Rose; Debili, Najet; Wittner, Monika; Kauskot, Alexandre; Pasquier, Florence; Antony-Debre, Ileana; Marty, Caroline; Vainchenker, William; Plo, Isabelle; Raslova, Hana .png)
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收藏ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesisBasso-Valentina, Francesca; Donada, Alessandro; Manchev, Vladimir T.; Lisetto, Manuel; Balayn, Nathalie; Martin, Jean Edouard; Muller, Delphine; Oyarzun, Cecilia Paola Marin; Duparc, Helene; Arkoun, Brahim; Cumin, Alessandro; Faivre, Lionel; Droin, Nathalie; Biunno, Ida; Pecci, Alessandro; Balduini, Alessandra; Debili, Najet; Antony-Debre, Ileana; Marty, Caroline; Vainchenker, William; Plo, Isabelle; Favier, Remi; Raslova, Hana 分享 收藏 Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia modelArkoun, Brahim; Robert, Elie; Boudia, Fabien; Mazzi, Stefania; Dufour, Virginie; Siret, Aurelie; Mammasse, Yasmine; Aid, Zakia; Vieira, Matthieu; Aygun, Imanci; Aglave, Marine; Cambot, Marie; Petermann, Rachel; Souquere, Sylvie; Rameau, Philippe; Catelain, Cyril; Diot, Romain; Tachdjian, Gerard; Hermine, Olivier; Droin, Nathalie; Debili, Najet; Plo, Isabelle; Malinge, Sebastien; Soler, Eric; Raslova, Hana; Mercher, Thomas; Vainchenker, William 分享 收藏 Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasmsEl-Khoury, Mira; Cabagnols, Xenia; Mosca, Matthieu; Vertenoeil, Gaelle; Marzac, Christophe; Favale, Fabrizia; Bluteau, Olivier; Lorre, Florence; Tisserand, Amandine; Moraes, Graciela Rabadan; Ugo, Valerie; Ianotto, Jean-Christophe; Rey, Jerome; Solary, Eric; Roy, Lydia; Rameau, Philippe; Debili, Najet; Pasquier, Florence; Casadevall, Nicole; Marty, Caroline; Constantinescu, Stefan N.; Raslova, Hana; Vainchenker, William; Plo, Isabelle 分享 收藏 Murine platelet production is suppressed by S1P release in the hematopoietic niche, not facilitated by blood S1P sensingNiazi, Hira; Zoghdani, Nesrine; Couty, Ludovic; Leuci, Alexandre; Nitzsche, Anja; Allende, Maria L.; Mariko, Boubacar; Ishaq, Rameez; Aslan, Yetki; Becker, Pierre Hadrien; Gazit, Salome L.; Poirault-Chassac, Sonia; Decouture, Benoit; Baudrie, Veronique; De Candia, Erica; Kono, Mari; Benarab, Ammar; Gaussem, Pascale; Tharaux, Pierre-Louis; Chun, Jerold; Provot, Sylvain; Debili, Najet; Therond, Patrice; Proia, Richard L.; Bachelot-Loza, Christilla; Camerer, Eric 分享 收藏 Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activityDynamins 2和3通过调节CXCR4表面表达和ITGB1活性来控制人巨核细胞的迁移Suraneni, Praveen K.; Corey, Seth J.; Hession, Michael J.; Ishaq, Rameez; Awomolo, Arinola; Hasan, Shirin; Shah, Chirag; Liu, Hui; Wickrema, Amittha; Debili, Najet; Crispino, John D.; Eklund, Elizabeth A.; Chen, Yolande 分享 收藏 Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defectMessaoudi, Kahia; Ali, Ashfaq; Ishaq, Rameez; Palazzo, Alberta; Sliwa, Dominika; Bluteau, Olivier; Souquere, Sylvie; Muller, Delphine; Diop, Khadija M.; Rameau, Philippe; Lapierre, Valerie; Marolleau, Jean-Pierre; Matthias, Patrick; Godin, Isabelle; Pierron, Gerard; Thomas, Steven G.; Watson, Stephen P.; Droin, Nathalie; Vainchenker, William; Plo, Isabelle; Raslova, Hana; Debili, Najet 分享 收藏 Mutations of the integrin αIIb/β3 intracytoplasmic salt bridge cause macrothrombocytopenia and enlarged platelet α-granulesFavier, Marie; Bordet, Jean-Claude; Favier, Remi; Gkalea, Vasiliki; Pillois, Xavier; Rameau, Philippe; Debili, Najet; Alessi, Marie-Christine; Nurden, Paquita; Raslova, Hana; Nurden, Alan 分享 收藏 The cell division control protein 42-Src family kinase-neural Wiskott-Aldrich syndrome protein pathway regulates human proplatelet formationPalazzo, A.; Bluteau, O.; Messaoudi, K.; Marangoni, F.; Chang, Y.; Souquere, S.; Pierron, G.; Lapierre, V.; Zheng, Y.; Vainchenker, W.; Raslova, H.; Debili, N. 分享 收藏 Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpointRoy, Anita; Lordier, Larissa; Pioche-Durieu, Catherine; Souquere, Sylvie; Roy, Lydia; Rameau, Philippe; Lapierre, Valerie; Le Cam, Eric; Plo, Isabelle; Debili, Najet; Raslova, Hana; Vainchenker, William 分享 收藏 Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignanciesSaliba, Joseph; Saint-Martin, Cecile; Di Stefano, Antonio; Lenglet, Gaelle; Marty, Caroline; Keren, Boris; Pasquier, Florence; Della Valle, Veronique; Secardin, Lise; Leroy, Gwendoline; Mahfoudhi, Emna; Grosjean, Sarah; Droin, Nathalie; Diop, M'boyba; Dessen, Philippe; Charrier, Sabine; Palazzo, Alberta; Merlevede, Jane; Meniane, Jean-Come; Delaunay-Darivon, Christine; Fuseau, Pascal; Isnard, Francoise; Casadevall, Nicole; Solary, Eric; Debili, Najet; Bernard, Olivier A.; Raslova, Hana; Najman, Albert; Vainchenker, William; Bellanne-Chantelot, Christine; Plo, Isabelle 分享 收藏 p19INK4d Controls Hematopoietic Stem Cells in a Cell-Autonomous Manner during Genotoxic Stress and through the Microenvironment during AgingHilpert, Morgane; Legrand, Celine; Bluteau, Dominique; Balayn, Natalie; Betems, Aline; Bluteau, Olivier; Villeval, Jean-Luc; Louache, Fawzia; Gonin, Patrick; Debili, Najet; Plo, Isabelle; Vainchenker, William; Gilles, Laure; Raslova, Hana 分享 收藏 Presence of a defect in karyokinesis during megakaryocyte endomitosisLordier, Larissa; Pan, Jiajia; Naim, Valeria; Jalil, Abdelali; Badirou, Idinath; Rameau, Philippe; Larghero, Jerome; Debili, Najet; Rosselli, Filippo; Vainchenker, William; Chang, Yunhua 分享 收藏 TET2 Deficiency Inhibits Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem CellsTET2缺陷抑制人胚胎干细胞的中胚层和造血分化Langlois, Thierry; Monte-Mor, Barbara da Costa Reis; Lenglet, Gaelle; Droin, Nathalie; Marty, Caroline; Le Couedic, Jean-Pierre; Almire, Carole; Auger, Nathalie; Mercher, Thomas; Delhommeau, Francois; Christensen, Jesper; Helin, Kristian; Debili, Najet; Fuks, Francois; Bernard, Olivier A.; Solary, Eric; Vainchenker, William; Plo, Isabelle 分享 收藏 Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivationBluteau, Dominique; Balduini, Alessandra; Balayn, Nathalie; Currao, Manuela; Nurden, Paquita; Deswarte, Caroline; Leverger, Guy; Noris, Patrizia; Perrotta, Silverio; Solary, Eric; Vainchenker, William; Debili, Najet; Favier, Remi; Raslova, Hana 分享 收藏 The abnormal proplatelet formation in MYH9-related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibitionChen, Y.; Boukour, S.; Milloud, R.; Favier, R.; Saposnik, B.; Schlegel, N.; Nurden, A.; Raslova, H.; Vainchenker, W.; Balland, M.; Nurden, P.; Debili, N. 分享 收藏 Crucial Role for Endoplasmic Reticulum Stress During Megakaryocyte MaturationLopez, Jose J.; Palazzo, Alberta; Chaabane, Chiraz; Albarran, Letizia; Polidano, Evelyne; Lebozec, Kristell; Dally, Saoussen; Nurden, Paquita; Enouf, Jocelyne; Debili, Najet; Bobe, Regis 分享 收藏 Developmental changes in human megakaryopoiesisBluteau, O.; Langlois, T.; Rivera-Munoz, P.; Favale, F.; Rameau, P.; Meurice, G.; Dessen, P.; Solary, E.; Raslova, H.; Mercher, T.; Debili, N.; Vainchenker, W. 分享 收藏 Thrombocytopenia induced by the histone deacetylase inhibitor abexinostat involves p53-dependent and -independent mechanismsAli, A.; Bluteau, O.; Messaoudi, K.; Palazzo, A.; Boukour, S.; Lordier, L.; Lecluse, Y.; Rameau, P.; Kraus-Berthier, L.; Jacquet-Bescond, A.; Lelievre, H.; Depil, S.; Dessen, P.; Solary, E.; Raslova, H.; Vainchenker, W.; Plo, I.; Debili, N. 分享 收藏 P53-dependent thrombocytopenia induced by the histone deacetylase inhibitor S78454Ali, Ashfaq; Bluteau, Olivier; Palazzo, Alberta; Boukour, Siham; Lordier, Larissa; Rameau, Philippe; Leceluse, Yann; Kraus-Berthier, Laurence; Jacquet-Bescond, Anne; Lelievre, Helene; Depil, Stephane; Solary, Eric; Raslova, Hana; Vainchenker, William; Plo, Isabelle; Debili, Najet 分享 收藏 
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