未登录 Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening Picco, Gabriele; Chen, Elisabeth D.; Alonso, Luz Garcia; Behan, Fiona M.; Goncalves, Emanuel; Bignell, Graham; Matchan, Angela; Fu, Beiyuan; Banerjee, Ruby; Andersonl, Elizabeth; Butler, Adam; Benes, Cyril H.; McDermott, Ultan; Dow, David; Iorio, Francesco; Stronach, Euan; Yang, Fengtang; Yusa, Kosuke; Saez-Rodriguez, Julio; Garnett, Mathew J. 分享 收藏
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors (vol 8, 1221, 2017) Cheng, Jiqiu; Demeulemeester, Jonas; Wedge, David C.; Vollan, Hans Kristian M.; Pitt, Jason J.; Russnes, Hege G.; Pandey, Bina P.; Nilsen, Gro; Nord, Silje; Bignell, Graham R.; White, Kevin P.; Borresen-Dale, Anne-Lise; Campbell, Peter J.; Kristensen, Vessela N.; Stratton, Michael R.; Lingjaerde, Ole Christian; Moreau, Yves; Van Loo, Peter 分享 收藏
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors (vol 8, 1221, 2017) Cheng, Jiqiu; Demeulemeester, Jonas; Wedge, David C.; Vollan, Hans Kristian M.; Pitt, Jason J.; Russnes, Hege G.; Pandey, Bina P.; Nilsen, Gro; Nord, Silje; Bignell, Graham R.; White, Kevin P.; Borresen-Dale, Anne-Lise; Campbell, Peter J.; Kristensen, Vessela N.; Stratton, Michael R.; Lingjaerde, Ole Christian; Moreau, Yves; Van Loo, Peter 分享 收藏
An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures Collord, Grace; Tarpey, Patrick; Kurbatova, Natalja; Martincorena, Inigo; Moran, Sebastian; Castro, Manuel; Nagy, Tibor; Bignell, Graham; Maura, Francesco; Young, Matthew D.; Berna, Jorge; Tubio, Jose M. C.; McMurran, Chris E.; Young, Adam M. H.; Sanders, Mathijs; Noorani, Imran; Price, Stephen J.; Watts, Colin; Leipnitz, Elke; Kirsch, Matthias; Schackert, Gabriele; Pearson, Danita; Devadass, Abel; Ram, Zvi; Collins, V. Peter; Allinson, Kieren; Jenkinson, Michael D.; Zakaria, Rasheed; Syed, Khaja; Hanemann, C. Oliver; Dunn, Jemma; McDermott, Michael W.; Kirollos, Ramez W.; Vassiliou, George S.; Esteller, Manel; Behjati, Sam; Brazma, Alvis; Santarius, Thomas; McDermott, Ultan 分享 收藏
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Transcription Factor Activities Enhance Markers of Drug Sensitivity in Cancer Garcia-Alonso, Luz; Iorio, Francesco; Matchan, Angela; Fonseca, Nuno; Jaaks, Patricia; Peat, Gareth; Pignatelli, Miguel; Falcone, Fiammetta; Benes, Cyril H.; Dunham, Ian; Bignell, Graham; McDade, Simon S.; Garnett, Mathew J.; Saez-Rodriguez, Julio 分享 收藏
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors Cheng, Jiqiu; Demeulemeester, Jonas; Wedge, David C.; Vollan, Hans Kristian M.; Pitt, Jason J.; Russnes, Hege G.; Pandey, Bina P.; Nilsen, Gro; Nord, Silje; Bignell, Graham R.; White, Kevin P.; Borresen-Dale, Anne-Lise; Campbell, Peter J.; Kristensen, Vessela N.; Stratton, Michael R.; Lingjrde, Ole Christian; Moreau, Yves; Van Loo, Peter 分享 收藏
New therapies for the treatment of BRAF/NRAS wild type melanoma Ranzani, Marco; Kemper, Kristel; Michaut, Magali; Krijgsman, Oscar; Iyer, Vivek; Speak, Anneliese; Nsengimana, Jeremie; Wong, Kim; Grinkevich, Vera; Aben, Nanne; Velasco-Herrera, Martin Del Castillo; Alsinet, Clara; Sjoberg, Marcela; Rashid, Mamunur; Turner, Gemma; Behan, Fiona; Supper, Emmanuelle; Thompson, Nicola; Bignell, Graham; Dutton-Regester, Ken; Pritchard, Antonia; Wong, Chi; McDermott, Ultan; Hayward, Nicholas K.; Yusa, Kosuke; Newton-Bishop, Julia; Wessels, Lodewyk; Garnett, Mathew; Peeper, Daniel; Adams, David 分享 收藏
Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations Brammeld, Jonathan S.; Petljak, Mia; Martincorena, Inigo; Williams, Steven P.; Alonso, Luz Garcia; Dalmases, Alba; Bellosillo, Beatriz; Robles-Espinoza, Carla Daniela; Price, Stacey; Barthorpe, Syd; Tarpey, Patrick; Alifrangis, Constantine; Bignell, Graham; Vidal, Joana; Young, Jamie; Stebbings, Lucy; Beal, Kathryn; Stratton, Michael R.; Saez-Rodriguez, Julio; Garnett, Mathew; Montagut, Clara; Iorio, Francesco; McDermott, Ultan 分享 收藏
Genomics of Drug Sensitivity in Cancer (GDSC): A resource for biomarker discovery in cancer cells Yang, W.; Lightfoot, H.; Bignell, G.; Behan, F.; Cokelear, T.; Haber, D.; Engelman, J.; Stratton, M.; Benes, C.; McDermott, U.; Garnett, M. 分享 收藏
A DNA target-enrichment approach to detect mutations, copy number changes and immunoglobulin translocations in multiple myeloma 一种检测多发性骨髓瘤中突变，拷贝数变化和免疫球蛋白易位的DNA靶标富集方法 Bolli, N.; Li, Y.; Sathiaseelan, V.; Raine, K.; Jones, D.; Ganly, P.; Cocito, F.; Bignell, G.; Chapman, M. A.; Sperling, A. S.; Anderson, K. C.; Avet-Loiseau, H.; Minvielle, S.; Campbell, P. J.; Munshi, N. C. 分享 收藏
Identification of new therapies for the treatment of BRAF/NRAS wild-type melanomas by functional screening approaches Ranzani, Marco; Michaut, Magali; Alsinet, Clara; Grinkevich, Vera; Wong, Kim; Iyer, Vivek; Aben, Nanne; Velasco-Herrera, Martin Del Castillo; Sjoberg, Marcela; Rashid, Mamunur; Bignell, Graham; Dutton-Regester, Ken; Pritchard, Antonia; Vis, Daniel; Turner, Gemma; McDermott, Ultan; Hayward, Nicholas K.; Yusa, Kosuke; Wessels, Lodewyk; Garnett, Mathew; Adams, David 分享 收藏
Monitoring metastatic melanoma treatment resistance using circulating tumour DNA Murphy, S.; Wan, J.; Gale, D.; Morris, J.; Mouliere, F.; Bignell, G.; Alifrangis, C.; Parkinson, C.; Durrani, A.; McDermott, U.; Massie, C.; Corrie, P.; Rosenfeld, N. 分享 收藏
Analysis of mutational signatures in exomes from B-cell lymphoma cell lines suggest APOBEC3 family members to be involved in the pathogenesis of primary effusion lymphoma Wagener, R.; Alexandrov, L. B.; Montesinos-Rongen, M.; Schlesner, M.; Haake, A.; Drexler, H. G.; Richter, J.; Bignell, G. R.; McDermott, U.; Siebert, R. 分享 收藏
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Processed pseudogenes acquired somatically during cancer development 在癌症发展过程中从体细胞获得的加工假基因 Cooke, Susanna L.; Shlien, Adam; Marshall, John; Pipinikas, Christodoulos P.; Martincorena, Inigo; Tubio, Jose M. C.; Li, Yilong; Menzies, Andrew; Mudie, Laura; Ramakrishna, Manasa; Yates, Lucy; Davies, Helen; Bolli, Niccolo; Bignell, Graham R.; Tarpey, Patrick S.; Behjati, Sam; Nik-Zainal, Serena; Papaemmanuil, Elli; Teixeira, Vitor H.; Raine, Keiran; O'Meara, Sarah; Dodoran, Maryam S.; Teague, Jon W.; Butler, Adam P.; Iacobuzio-Donahue, Christine; Santarius, Thomas; Grundy, Richard G.; Malkin, David; Greaves, Mel; Munshi, Nikhil; Flanagan, Adrienne M.; Bowtell, David; Martin, Sancha; Larsimont, Denis; Reis-Filho, Jorge S.; Boussioutas, Alex; Taylor, Jack A.; Hayes, D. Neil; Janes, Sam M.; Futreal, P. Andrew; Stratton, Michael R.; McDermott, Ultan; Campbell, Peter J. 分享 收藏
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma 多发性骨髓瘤基因组进化和突变谱的异质性 Bolli, Niccolo; Avet-Loiseau, Herve; Wedge, David C.; Van Loo, Peter; Alexandrov, Ludmil B.; Martincorena, Inigo; Dawson, Kevin J.; Iorio, Francesco; Nik-Zainal, Serena; Bignell, Graham R.; Hinton, Jonathan W.; Li, Yilong; Tubio, Jose M. C.; McLaren, Stuart; Meara, Sarah O'; Butler, Adam P.; Teague, Jon W.; Mudie, Laura; Anderson, Elizabeth; Rashid, Naim; Tai, Yu-Tzu; Shammas, Masood A.; Sperling, Adam S.; Fulciniti, Mariateresa; Richardson, Paul G.; Parmigiani, Giovanni; Magrangeas, Florence; Minvielle, Stephane; Moreau, Philippe; Attal, Michel; Facon, Thierry; Futreal, P. Andrew; Anderson, Kenneth C.; Campbell, Peter J.; Munshi, Nikhil C. 分享 收藏
Whole exome sequencing of adenoid cystic carcinoma Stephens, Philip J.; Davies, Helen R.; Mitani, Yoshitsugu; Van Loo, Peter; Shlien, Adam; Tarpey, Patrick S.; Papaemmanuil, Elli; Cheverton, Angela; Bignell, Graham R.; Butler, Adam R.; Gamble, John; Gamble, Stephen; Hardy, Claire; Hinton, Jonathan; Jia, Mingming; Jayakuniar, Alagu; Jones, David; Latimer, Calli; McLaren, Stuart; McBride, David J.; Menzies, Andrew; Mudie, Laura; Maddison, Mark; Raine, Keiran; Nik-Zainal, Serena; O'Meara, Sarah; Teague, Jon W.; Varela, Ignacio; Wedge, David C.; Whitmore, Ian; Lippman, Scott M.; McDermott, Ultan; Stratton, Michael R.; Campbell, Peter J.; El-Naggar, Adel K.; Futreal, P. Andrew 分享 收藏
Single-cell paired-end genome sequencing reveals structural variation per cell cycle Voet, Thierry; Kumar, Parveen; Van Loo, Peter; Cooke, Susanna L.; Marshall, John; Lin, Meng-Lay; Esteki, Masoud Zamani; Van der Aa, Niels; Mateiu, Ligia; McBride, David J.; Bignell, Graham R.; McLaren, Stuart; Teague, Jon; Butler, Adam; Raine, Keiran; Stebbings, Lucy A.; Quail, Michael A.; D'Hooghe, Thomas; Moreau, Yves; Futreal, P. Andrew; Stratton, Michael R.; Vermeesch, Joris R.; Campbell, Peter J. 分享 收藏
Recurrent SETBP1 mutations in atypical chronic myeloid leukemia Piazza, Rocco; Valletta, Simona; Winkelmann, Nils; Redaelli, Sara; Spinelli, Roberta; Pirola, Alessandra; Antolini, Laura; Mologni, Luca; Donadoni, Carla; Papaemmanuil, Elli; Schnittger, Susanne; Kim, Dong-Wook; Boultwood, Jacqueline; Rossi, Fabio; Gaipa, Giuseppe; De Martini, Greta P.; Di Celle, Paola Francia; Jang, Hyun Gyung; Fantin, Valeria; Bignell, Graham R.; Magistroni, Vera; Haferlach, Torsten; Pogliani, Enrico Maria; Campbell, Peter J.; Chase, Andrew J.; Tapper, William J.; Cross, Nicholas C. P.; Gambacorti-Passerini, Carlo 分享 收藏
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