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S

Stephen J. Tucker

university of oxford

51H指数
291论文数
9.1K被引数
收录论文 49
发表时间
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Light-induced analgesia provides a drug-free optical method for pain relief via activation of TRAAK k+ channels光诱导镇痛提供了一种通过激活TRAAK k通道缓解疼痛的无药物光学方法
errNature Communications
IF15.7
err2026-01-26
err0
errOAAI
errMarion Bied; Arnaud Landra-Willm; Anne Amandine Chassot; Edward Francisco Mendez-Otalvaro; Benjamin Sueur; Kilian Roßmann; Elvira de la Peña; Pascal Fossat; Stephen J. Tucker; Jacques Noël; Wojciech Kopec; Felix Viana; Johannes Broichhagen; Eric Boué-Grabot; Guillaume Sandoz
err分享
err收藏
Cryo-EM structure of the human THIK-1 K2P K+ channel reveals a lower Y gate regulated by lipids and anesthetics人源THIK-1 K2P K+通道的冷冻电镜结构揭示了一个受脂质和麻醉剂调控的Y门控结构。
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2025-02-26
err2
errOAAI
errRoedstroem, Karin E. J.; Eymsh, Bisher; Proks, Peter; Hayre, Mehtab S.; Cordeiro, Soenke; Mendez-Otalvaro, Edward; Madry, Christian; Rowland, Anna; Baukrowitz, Thomas; Schewe, Marcus; Tucker, Stephen J.
err分享
err收藏
Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl- Channel
errJOURNAL OF CHEMICAL THEORY AND COMPUTATION
IF5.5
err2025-01-03
err0
PREAI
errPhan, Linda X.; Owji, Aaron P.; Yang, Tingting; Crain, Jason; Sansom, Mark S. P.; Tucker, Stephen J.
err分享
err收藏
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation
errNATURE COMMUNICATIONS
IF15.7
err2024-05-16
err2
errOAAI
errRodstrom, Karin E. J.; Cloake, Alexander; Sormann, Janina; Baronina, Agnese; Smith, Kathryn H. M.; Pike, Ashley C. W.; Ang, Jackie; Proks, Peter; Schewe, Marcus; Holland-Kaye, Ingelise; Bushell, Simon R.; Elliott, Jenna; Pardon, Els; Baukrowitz, Thomas; Owens, Raymond J.; Newstead, Simon; Steyaert, Jan; Carpenter, Elisabeth P.; Tucker, Stephen J.
err分享
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Influence of electronic polarization on the binding of anions to a chloride-pumping rhodopsin
errBIOPHYSICAL JOURNAL
IF3.1
err2023-04-01
err5
errOAAI
errPhan, Linda X.; Chamorro, Victor Cruces; Martinez-Seara, Hector; Crain, Jason; Sansom, Mark S. P.; Tucker, Stephen J.
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When is a hydrophobic gate not a hydrophobic gate?
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2022-10-26
err5
errOAAI
errSeiferth, David; Biggin, Philip C.; Tucker, Stephen J.
err分享
err收藏
Gain-of-function mutations in KCNK3 cause a developmental disorder with sleep apnea
errNATURE GENETICS
IF31.8
err2022-10-04
err11
errOAAI
errSormann, Janina; Schewe, Marcus; Proks, Peter; Jouen-Tachoire, Thibault; Rao, Shanlin; Riel, Elena B.; Agre, Katherine E.; Begtrup, Amber; Dean, John; Descartes, Maria; Fischer, Jan; Gardham, Alice; Lahner, Carrie; Mark, Paul R.; Muppidi, Srikanth; Pichurin, Pavel N.; Porrmann, Joseph; Schallner, Jens; Smith, Kirstin; Straub, Volker; Vasudevan, Pradeep; Willaert, Rebecca; Carpenter, Elisabeth P.; Rodstrom, Karin E. J.; Hahn, Michael G.; Mueller, Thomas; Baukrowitz, Thomas; Hurles, Matthew E.; Wright, Caroline F.; Tucker, Stephen J.
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Structural basis for proton coupled cystine transport by cystinosin胱氨酸蛋白质子偶联胱氨酸转运的结构基础
errNATURE COMMUNICATIONS
IF15.7
err2022-08-17
err11
errOAAI
errLobel, Mark; Salphati, Sacha P.; El Omari, Kamel; Wagner, Armin; Tucker, Stephen J.; Parker, Joanne L.; Newstead, Simon
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Influence of effective polarization on ion and water interactions within a biomimetic nanopore有效极化对仿生纳米孔内离子和水相互作用的影响
errBIOPHYSICAL JOURNAL
IF3.1
err2022-06-01
err5
errOAAI
errPhan, Linda X.; Lynch, Charlotte, I; Crain, Jason; Sansom, Mark S. P.; Tucker, Stephen J.
err分享
err收藏
Transition between conformational states of the TREK-1 K2P channel promoted by interaction with PIP2
errBIOPHYSICAL JOURNAL
IF3.1
err2022-06-01
err5
errOAAI
errPanasawatwong, Adisorn; Pipatpolkai, Tanadet; Tucker, Stephen J.
err分享
err收藏
Water Nanoconfined in a Hydrophobic Pore: Molecular Dynamics Simulations of Transmembrane Protein 175 and the Influence of Water Models疏水孔中的水纳米约束: 跨膜蛋白175的分子动力学模拟和水模型的影响
errACS NANO
IF16
err2021-11-16
err17
errOAAI
errLynch, Charlotte, I; Klesse, Gianni; Rao, Shanlin; Tucker, Stephen J.; Sansom, Mark S. P.
err分享
err收藏
Ion channels as convergence points in the pathology of pulmonary arterial hypertension
errBIOCHEMICAL SOCIETY TRANSACTIONS
IF4.3
err2021-08-04
err10
errOAAI
errJouen-Tachoire, Thibault R. H.; Tucker, Stephen J.; Tammaro, Paolo
err分享
err收藏
Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2021-05-25
err22
errOAAI
errProks, Peter; Schewe, Marcus; Conrad, Linus J.; Rao, Shanlin; Rathje, Kristin; Rodstrom, Karin E. J.; Carpenter, Elisabeth P.; Baukrowitz, Thomas; Tucker, Stephen J.
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The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion
errDIABETES
IF7.5
err2021-02-10
err11
errOAAI
errSachse, Gregor; Haythorne, Elizabeth; Hill, Thomas; Proks, Peter; Joynson, Russell; Terron-Exposito, Raul; Bentley, Liz; Tucker, Stephen J.; Cox, Roger D.; Ashcroft, Frances M.
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Electric Field Induced Wetting of a Hydrophobic Gate in a Model Nanopore Based on the 5-HT3 Receptor Channel基于5-HT3受体通道的模型纳米孔中疏水门的电场诱导润湿
errACS NANO
IF16
err2020-07-16
err28
errOAAI
errKlesse, Gianni; Tucker, Stephen J.; Sansom, Mark S. P.
err分享
err收藏
Induced Polarization in Molecular Dynamics Simulations of the 5-HT3 Receptor Channel
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2020-04-27
err39
errOAAI
errKlesse, Gianni; Rao, Shanlin; Tucker, Stephen J.; Sansom, Mark S. P.
err分享
err收藏
Structure and assembly of calcium homeostasis modulator proteins (vol 27, pg 150, 2019)
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2020-02-17
err4
errOAAI
errSyrjanen, Johanna L.; Michalski, Kevin; Chou, Tsung-Han; Grant, Timothy; Rao, Shanlin; Simorowski, Noriko; Tucker, Stephen J.; Grigorieff, Nikolaus; Furukawa, Hiro
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err收藏
Structure and assembly of calcium homeostasis modulator proteins
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2020-01-27
err61
errOAAI
errSyrjanen, Johanna L.; Michalski, Kevin; Chou, Tsung-Han; Grant, Timothy; Rao, Shanlin; Simorowski, Noriko; Tucker, Stephen J.; Grigorieff, Nikolaus; Furukawa, Hiro
err分享
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Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ channel
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-01-01
err17
errOAAI
errNematian-Ardestani, Ehsan; Abd-Wahab, Firdaus; Chatelain, Franck C.; Sun, Han; Schewe, Marcus; Baukrowitz, Thomas; Tucker, Stephen J.
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A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2019-06-24
err47
errOAAI
errRao, Shanlin; Klesse, Gianni; Stansfeld, Phillip J.; Tucker, Stephen J.; Sansom, Mark S. P.
err分享
err收藏

研究方向

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合作学者
合作期刊
M
Matthew E. Hurles
H 指数: 118 · 论文数: 388
M
Mark S.P. Sansom
H 指数: 105 · 论文数: 962
V
Volker Straub
H 指数: 101 · 论文数: 962
F
Frances M. Ashcroft
H 指数: 90 · 论文数: 396
B
Bert L. de Groot
H 指数: 78 · 论文数: 374
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