Keith W. Caldecott - Publications, H-index & Citations

Keith W. Caldecott

institute of molecular genetics of the czech academy of sciences

73H指数

214论文数

1.8W被引数

收录论文 32

发表时间

FEN1 is critical for rapid single-strand break repair in G1 phase Burdova, K.; Hailstone, R.; Hanzlikova, H.; Caldecott, K.W. FEN1是G1期快速单链断裂修复的关键因子。Nucleic Acids Res. 2025, 53, gkaf710. [Google Scholar] [CrossRef] [PubMed]

NUCLEIC ACIDS RESEARCH

IF13.1

2025-08-12

OAAI

Burdova, Kamila; Hailstone, Richard; Hanzlikova, Hana; Caldecott, Keith W.

Mechanism of cytarabine-induced neurotoxicity 阿糖胞苷的神经毒性机制

Nature

IF48.5

2025-06-25

PREAI

Jia-Cheng Liu; Dongpeng Wang; Elsa Callen; Chuanyuan Chen; Santiago Noriega; Yafang Shang; David Schürmann; Yawei Song; Gokul N. Ramadoss; Raj Chari; Nancy Wong; Yongge Zhao; Yuan He; Peter D. Aplan; Michael E. Ward; Nathaniel Heintz; Anjana Rao; Peter J. McKinnon; Keith W. Caldecott; Primo Schär; Fei-Long Meng; Ferenc Livak; Wei Wu; André Nussenzweig

Dispensability of HPF1 for cellular removal of DNA single-strand breaks

NUCLEIC ACIDS RESEARCH

IF13.1

2024-08-20

OAAI

Hrychova, Kristyna; Burdova, Kamila; Polackova, Zuzana; Giamaki, Despoina; Valtorta, Beatrice; Brazina, Jan; Krejcikova, Katerina; Kuttichova, Barbora; Caldecott, Keith W.; Hanzlikova, Hana

PARP1-dependent DNA-protein crosslink repair

NATURE COMMUNICATIONS

IF15.7

2024-08-05

OAAI

Fabian, Zita; Kakulidis, Ellen S.; Hendriks, Ivo A.; Kuhbacher, Ulrike; Larsen, Nicolai B.; Oliva-Santiago, Marta; Wang, Junhui; Leng, Xueyuan; Dirac-Svejstrup, A. Barbara; Svejstrup, Jesper Q.; Nielsen, Michael L.; Caldecott, Keith; Duxin, Julien P.

DNA combing versus DNA spreading and the separation of sister chromatids

JOURNAL OF CELL BIOLOGY

IF6.4

2024-02-05

OAAI

Meroni, Alice; Wells, Sophie E.; Fonseca, Carmen; Chaudhuri, Arnab Ray; Caldecott, Keith W.; Vindigni, Alessandro

APE1-dependent base excision repair of DNA photodimers in human cells

MOLECULAR CELL

IF16.6

2023-10-01

OAAI

Gautam, Amit; Fawcett, Heather; Burdova, Kamila; Brazina, Jan; Caldecott, Keith W.

Inactivating TDP2 missense mutation in siblings with congenital abnormalities reminiscent of fanconi anemia

HUMAN GENETICS

IF3.6

2023-08-10

OAAI

Zagnoli-Vieira, Guido; Brazina, Jan; van den Bogaert, Kris; Huybrechts, Wim; Molenaers, Guy; Caldecott, Keith W. W.; Van Esch, Hilde

Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity

EMBO JOURNAL

IF8.3

2023-07-26

OAAI

Serrano-Benitez, Almudena; Wells, Sophie E.; Drummond-Clarke, Lylah; Russo, Lilian C.; Thomas, John Christopher; Leal, Giovanna A.; Farrow, Mark; Edgerton, James Michael; Balasubramanian, Shankar; Yang, Ming; Frezza, Christian; Gautam, Amit; Brazina, Jan; Burdova, Kamila; Hoch, Nicolas C.; Jackson, Stephen P.; Caldecott, Keith W.

A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

120

OAAI

Taylor, RM; Moore, DJ; Whitehouse, J; Johnson, P; Caldecott, KW

Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

165

OAAI

Taylor, RM; Thistlethwaite, A; Caldecott, KW

APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

160

OAAI

Iles, Natasha; Rulten, Stuart; El-Khamisy, Sherif F.; Caldecott, Keith W.

BRAT1 links Integrator and defective RNA processing with neurodegeneration

NATURE COMMUNICATIONS

IF15.7

2022-08-26

OAAI

Cihlarova, Zuzana; Kubovciak, Jan; Sobol, Margarita; Krejcikova, Katerina; Sachova, Jana; Kolar, Michal; Stanek, David; Barinka, Cyril; Yoon, Grace; Caldecott, Keith W.; Hanzlikova, Hana

PARP inhibition impedes the maturation of nascent DNA strands during DNA replication

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-03-24

OAAI

Vaitsiankova, Alina; Burdova, Kamila; Sobol, Margarita; Gautam, Amit; Benada, Oldrich; Hanzlikova, Hana; Caldecott, Keith W.

The threat of programmed DNA damage to neuronal genome integrity and plasticity

NATURE GENETICS

IF31.8

2022-02-10

PREAI

Caldecott, Keith W.; Ward, Michael E.; Nussenzweig, Andre

XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair

NATURE CELL BIOLOGY

IF19.1

2021-11-22

OAAI

Adamowicz, Marek; Hailstone, Richard; Demin, Annie A.; Komulainen, Emilia; Hanzlikova, Hana; Brazina, Jan; Gautam, Amit; Wells, Sophie E.; Caldecott, Keith W.

The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-09-01

OAAI

Russo, Lilian Cristina; Tomasin, Rebeka; Matos, Isaac Araujo; Manucci, Antonio Carlos; Sowa, Sven T.; Dale, Katie; Caldecott, Keith W.; Lehtio, Lari; Schechtman, Deborah; Meotti, Flavia C.; Bruni-Cardoso, Alexandre; Hoch, Nicolas Carlos

Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures

EMBO REPORTS

IF6.2

2021-05-01

OAAI

Komulainen, Emilia; Badman, Jack; Rey, Stephanie; Rulten, Stuart; Ju, Limei; Fennell, Kate; Kalasova, Ilona; Ilievova, Kristyna; McKinnon, Peter J.; Hanzlikova, Hana; Staras, Kevin; Caldecott, Keith W.

Untangling trapped topoisomerases with tyrosyl-DNA phosphodiesterases

DNA REPAIR

IF2.7

2020-10-01

PREAI

Zagnoli-Vieira, Guido; Caldecott, Keith W.

Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair

NATURE COMMUNICATIONS

IF15.7

2020-07-07

OAAI

Hanzlikova, Hana; Prokhorova, Evgeniia; Krejcikova, Katerina; Cihlarova, Zuzana; Kalasova, Ilona; Kubovciak, Jan; Sachova, Jana; Hailstone, Richard; Brazina, Jan; Ghosh, Shereen; Cirak, Sebahattin; Gleeson, Joseph G.; Ahel, Ivan; Caldecott, Keith W.

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair

NUCLEIC ACIDS RESEARCH

IF13.1

2020-06-06

OAAI

Kalasova, Ilona; Hailstone, Richard; Bublitz, Janin; Bogantes, Jovel; Hofmann, Winfried; Leal, Alejandro; Hanzlikova, Hana; Caldecott, Keith W.

研究方向