未登录 TBXA2R activates ERMs to drive motility, invasion, and metastatic colonization of TNBC cells 血栓素A2受体激活ERM蛋白以驱动三阴性乳腺癌细胞的迁移、侵袭和转移性定植 Leguay, Kevin; Naffati, Omaima; Kiyan, Camila Lie; He, Yu Yan; Hogue, Mireille; Tesniere, Chloe; Gombos, Melania; Kuasne, Hellen; Gaboury, Louis; Le Gouill, Christian; Meloche, Sylvain; Bouvier, Michel; Carreno, Sebastien 分享 收藏
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CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling Serwe, Guillaume; Kachaner, David; Gagnon, Jessica; Plutoni, Cedric; Lajoie, Driss; Durame, Eloise; Sahmi, Malha; Garrido, Damien; Lefrancois, Martin; Arseneault, Genevieve; Saba-El-Leil, Marc K.; Meloche, Sylvain; Emery, Gregory; Therrien, Marc 分享 收藏
Discovery of Benzodiazepine-Based Inhibitors of the E2 Enzyme UBCH10 from a Cell-Based p21 Degradation Screen Pelletier, Benoit; Duhamel, Stephanie; Tambutet, Guillaume; Jarvis, Scott; Cleroux, Patrick; David, Maud; Tanguay, Pierre-Luc; Voisin, Laure; James, Clint; Lavoie, Rico; Gareau, Yves; Flynn-Robitaille, Joel; Lorca, Thierry; Ruel, Rejean; Marinier, Anne; Meloche, Sylvain 分享 收藏
The Catalytic Activity of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 3 Is Required To Sustain CD4+ CD8+ Thymocyte Survival Marquis, Miriam; Daudelin, Jean-Francois; Boulet, Salix; Sirois, Julien; Crain, Karinn; Mathien, Simon; Turgeon, Benjamin; Rousseau, Justine; Meloche, Sylvain; Labrecque, Nathalie 分享 收藏
The Extracellular Signal-Regulated Kinase 3 (Mitogen-Activated Protein Kinase 6 [MAPK6])-MAPK-Activated Protein Kinase 5 Signaling Complex Regulates Septin Function and Dendrite Morphology 细胞外信号调节激酶3 (丝裂原活化蛋白激酶6 [MAPK6])-MAPK活化蛋白激酶5信号复合物调节Septin功能和树突形态 Brand, Frank; Schumacher, Stefanie; Kant, Shashi; Menon, Manoj B.; Simon, Ruth; Turgeon, Benjamin; Britsch, Stefan; Meloche, Sylvain; Gaestel, Matthias; Kotlyarova, Alexey 分享 收藏
Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration Pyakurel, Aswin; Balmer, Delphine; Saba-El-Leil, Marc K.; Kizilyaprak, Caroline; Daraspe, Jean; Humbel, Bruno M.; Voisin, Laure; Le, Yun Z.; von Lintig, Johannes; Meloche, Sylvain; Roduit, Raphael 分享 收藏
CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma Houles, Thibault; Lavoie, Genevieve; Nourreddine, Sami; Cheung, Winnie; Vaillancourt-Jean, Eric; Guerin, Celia M.; Bouttier, Mathieu; Grondin, Benoit; Lin, Sichun; Saba-El-Leil, Marc K.; Angers, Stephane; Meloche, Sylvain; Roux, Philippe P. 分享 收藏
Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis Girondel, Charlotte; Levesque, Kim; Langlois, Marie-Josee; Pasquin, Sarah; Saba-El-Leil, Marc K.; Rivard, Nathalie; Friesel, Robert; Servant, Marc J.; Gauchat, Jean-Francois; Lesage, Sylvie; Meloche, Sylvain 分享 收藏
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer Aubert, Leo; Nandagopal, Neethi; Steinhart, Zachary; Lavoie, Genevieve; Nourreddine, Sami; Berman, Jacob; Saba-El-Leil, Marc K.; Papadopoli, David; Lin, Sichun; Hart, Traver; Macleod, Graham; Topisirovic, Ivan; Gaboury, Louis; Fahrni, Christoph J.; Schramek, Daniel; Meloche, Sylvain; Angers, Stephane; Roux, Philippe P. 分享 收藏
Visualization of Endogenous ERK1/2 in Cells with a Bioorthogonal Covalent Probe Sipthorp, James; Lebraud, Honorine; Gilley, Rebecca; Kidger, Andrew M.; Okkenhaug, Hanneke; Saba-El-Lei, Marc; Meloche, Sylvain; Caunt, Christopher J.; Cook, Simon J.; Heightman, Tom D. 分享 收藏
The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias Lavallee, Vincent-Philippe; Baccelli, Irsne; Krosl, Jana; Wilhelm, Brian; Barabe, Frederic; Gendron, Patrick; Boucher, Genevieve; Lemieux, Sebastien; Marinier, Anne; Meloche, Sylvain; Hebert, Josee; Sauvageau, Guy 分享 收藏
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