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Somatic alterations in primary tumors of patients (pts) with metastatic breast cancer (MBC) may predict likelihood of brain metastasis Kabraji, Sheheryar; Li, Yvonne Y.; Hughes, Melissa E.; Gupta, Hersh V.; Buckley, Lauren; Files, Janet L.; Mohammed-Abreu, Ayesha; Feeney, Anne-Marie; Kirkner, Greg; Patel, Ashka; Garrido-Castro, Ana C.; Barroso-Sousa, Romualdo; Bychkovsky, Brittany; Meyerson, Matthew; Tolaney, Sara; Dillon, Deborah A.; Johnson, Bruce; Winer, Eric; Cherniack, Andrew; Lin, Nancy U. 分享 收藏
Tumor Genomic Landscape in Older Women with Metastatic Breast Cancer (MBC) Gupta, Hersh V.; Freedman, Rachel; Hughes, Melissa E.; Li, Yvonne Y.; Kirkner, Gregory; Files, Janet L.; Strauss, Sarah; Garrido-Castro, Ana C.; Buckley, Lauren; Barroso-Sousa, Romualdo; Bychkovsky, Brittany; Tolaney, Sara; MacConaill, Laura; Lindeman, Neal; Johnson, Bruce; Meyerson, Matthew; Winer, Eric; Dillon, Deborah A.; Cherniack, Andrew; Lin, Nancy U. 分享 收藏
Comprehensive genomic characterization of HER2-low breast cancer Tarantino, Paolo; Gupta, Hersh V.; Hughes, Melissa E.; Files, Janet L.; Strauss, Sarah; Kirkner, Gregory; Feeney, Anne-Marie; Li, Yvonne Y.; Garrido-Castro, Ana C.; Barroso-Sousa, Romualdo; Bychkovsky, Brittany; MacConaill, Laura; Lindeman, Neal; Johnson, Bruce; Meyerson, Matthew; Kabraji, Sheheryar; Jeselsohn, Rinath; Qiu, Xintao; Li, Rong; Long, Henry W.; Winer, Eric; Dillon, Deborah A.; Curigliano, Giuseppe; Cherniack, Andrew; Tolaney, Sara; Lin, Nancy U. 分享 收藏
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Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q (vol 33, pg 108493, 2020) Neggers, Jasper E.; Paolella, Brenton R.; Asfaw, Adhana; Rothberg, Michael V.; Skipper, Thomas A.; Yang, Annan; Kalekar, Radha L.; Krill-Burger, John M.; Dharia, Neekesh V.; Kugener, Guillaume; Kalfon, Jeremie; Yuan, Chen; Dumont, Nancy; Gonzalez, Alfredo; Abdusamad, Mai; Li, Yvonne Y.; Spurr, Liam F.; Wu, Westley W.; Durbin, Adam D.; Wolpin, Brian M.; Piccioni, Federica; Root, David E.; Boehm, Jesse S.; Cherniack, Andrew D.; Tsherniak, Aviad; Hong, Andrew L.; Hahn, William C.; Stegmaier, Kimberly; Golub, Todd R.; Vazquez, Francisca; Aguirre, Andrew J. 分享 收藏
Discovery and Features of an Alkylating Signature in Colorectal Cancer Gurjao, Carino; Zhong, Rong; Haruki, Koichiro; Li, Yvonne Y.; Spurr, Liam F.; Lee-Six, Henry; Reardon, Brendan; Ugai, Tomotaka; Zhang, Xuehong; Cherniack, Andrew D.; Song, Mingyang; Van Allen, Eliezer M.; Meyerhardt, Jeffrey A.; Nowak, Jonathan A.; Giovannucci, Edward L.; Fuchs, Charles S.; Wu, Kana; Ogino, Shuji; Giannakis, Marios 分享 收藏
FGFR2 Extracellular Domain In-Frame Deletions Are Therapeutically Targetable Genomic Alterations That Function as Oncogenic Drivers in Cholangiocarcinoma Cleary, James M.; Raghavan, Srivatsan; Wu, Qibiao; Li, Yvonne Y.; Spurr, Liam F.; Gupta, Hersh, V; Rubinson, Douglas A.; Fetter, Isobel J.; Hornick, Jason L.; Nowak, Jonathan A.; Siravegna, Giulia; Goyal, Lipika; Shi, Lei; Brais, Lauren K.; Loftus, Maureen; Shinagare, Atul B.; Abrams, Thomas A.; Clancy, Thomas E.; Wang, Jiping; Patel, Anuj K.; Brichory, Franck; Chessex, Anne Vaslin; Sullivan, Ryan J.; Keller, Rachel B.; Denning, Sarah; Hill, Emma R.; Shapiro, Geoffrey, I; Pokorska-Bocci, Anna; Zanna, Claudio; Ng, Kimmie; Schrag, Deborah; Janne, Pasi A.; Hahn, William C.; Cherniack, Andrew D.; Corcoran, Ryan B.; Meyerson, Matthew; Daina, Antoine; Zoete, Vincent; Bardeesy, Nabeel; Wolpin, Brian M. 分享 收藏
Genomic Characterization of de novo Metastatic Breast Cancer Garrido-Castro, Ana C.; Spurr, Liam F.; Hughes, Melissa E.; Li, Yvonne Y.; Cherniack, Andrew D.; Kumari, Priti; Lloyd, Maxwell R.; Bychkovsky, Brittany; Barroso-Sousa, Romualdo; Di Lascio, Simona; Jain, Esha; Files, Janet; Mohammed-Abreu, Ayesha; Krevalin, Max; MacKichan, Colin; Barry, William T.; Guo, Hao; Xia, Daniel; Cerami, Ethan; Rollins, Barrett J.; MacConaill, Laura E.; Lindeman, Neal, I; Krop, Ian E.; Johnson, Bruce E.; Wagle, Nikhil; Winer, Eric P.; Dillon, Deborah A.; Lin, Nancy U. 分享 收藏
Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions Singh, Harshabad; Li, Yvonne Y.; Spurr, Liam F.; Shinagare, Atul B.; Abhyankar, Ritika; Reilly, Emma; Brais, Lauren K.; Nag, Anwesha; Ducar, Matthew D.; Thorner, Aaron R.; Shapiro, Geoffrey, I; Keller, Rachel B.; Siletti, Cheta; Clark, Jeffrey W.; Farago, Anna F.; Lin, Jessica J.; Demetri, George D.; Gujrathi, Rahul; Kulke, Matthew H.; MacConaill, Laura E.; Ligon, Azra H.; Sicinska, Ewa; Meyerson, Matthew L.; Meyerhardt, Jeffrey A.; Cherniack, Andrew D.; Wolpin, Brian M.; Ng, Kimmie; Giannakis, Marios; Hornick, Jason L.; Cleary, James M. 分享 收藏
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q Neggers, Jasper E.; Paolella, Brenton R.; Asfaw, Adhana; Rothberg, Michael, V; Skipper, Thomas A.; Yang, Annan; Kalekar, Radha L.; Krill-Burger, John M.; Dharia, Neekesh, V; Kugener, Guillaume; Kalfon, Jeremie; Yuan, Chen; Dumont, Nancy; Gonzalez, Alfredo; Abdusamad, Mai; Li, Yvonne Y.; Spurr, Liam F.; Wu, Westley W.; Durbin, Adam D.; Wolpin, Brian M.; Piccioni, Federica; Root, David E.; Boehm, Jesse S.; Cherniack, Andrew D.; Tsherniak, Aviad; Hong, Andrew L.; Hahn, William C.; Stegmaier, Kimberly; Golub, Todd R.; Vazquez, Francisca; Aguirre, Andrew J. 分享 收藏
Near haploidization is a genomic hallmark which defines a molecular subgroup of giant cell glioblastoma Baker, Tiffany G.; Alden, Jay; Dubuc, Adrian M.; Welsh, Cynthia T.; Znoyko, Iya; Cooley, Linda D.; Farooqi, Midhat S.; Schwartz, Stuart; Li, Yvonne Y.; Cherniack, Andrew D.; Lindhorst, Scott M.; Gener, Melissa; Wolff, Daynna J.; Meredith, David M. 分享 收藏
Genomic correlates of PD-L1 expression are associated with response to immunotherapy in non-small cell lung cancer Spurr, Liam F.; Lamberti, Giuseppe; Li, Yvonne Y.; Ricciuti, Biagio; Recondo, Gonzalo; Umeton, Renato; Sholl, Lynette M.; Meyerson, Matthew L.; Cherniack, Andrew D.; Awad, Mark M. 分享 收藏
FGFR2 in-frame indels: A novel targetable alteration in intrahepatic cholangiocarcinoma Li, Yvonne Y.; Cleary, James M.; Raghavan, Srivatsan; Spurr, Liam F.; Wu, Qibiao; Shi, Lei; Brais, Lauren K.; Loftus, Maureen; Goyal, Lipika; Patel, Anuj K.; Shinagare, Atul B.; Clancy, Thomas E.; Shapiro, Geoffrey; Cerami, Ethan; Sellers, William R.; Hahn, William C.; Meyerson, Matthew; Bardeesy, Nabeel; Cherniack, Andrew D.; Wolpin, Brian M. 分享 收藏
VPS4A is a synthetic lethal target in VPS4B-deficient cancers due to co-deletion with SMAD4 Neggers, Jasper E.; Paolella, Brenton R.; Asfaw, Adhana; Rothberg, Michael, V; Skipper, Thomas A.; Kalekar, Radha L.; Krill-Burger, John M.; Hong, Andrew L.; Kugener, Guillaume; Kalfon, Jeremie; Yang, Annan; Yuan, Chen; Dumont, Nancy; Gonzalez, Alfredo; Abdusamad, Mai; Li, Yvonne Y.; Spurr, Liam F.; Wu, Westley W.; Piccioni, Federica; Wolpin, Brian M.; Root, David E.; Boehm, Jesse S.; Cherniack, Andrew D.; Tsherniak, Aviad; Golub, Todd R.; Vazquez, Francisca; Aguirre, Andrew J. 分享 收藏
Mechanisms and therapeutic implications of hypermutation in gliomas Touat, Mehdi; Li, Yvonne Y.; Boynton, Adam N.; Spurr, Liam F.; Iorgulescu, Bryan; Bohrson, Craig L.; Cortes-Ciriano, Isidro; Geduldig, Jack E.; Pelton, Kristine; Lim-Fat, Mary J.; Pal, Sangita; Ramkissoon, Shakti H.; Dubois, Frank; Bellamy, Charlotte; Currimjee, Naomi; Qian, Kenin; Malinowski, Seth; Shetty, Aniket; Chow, Kin-Hoe; Verreault, Maite; Guillerm, Erell; Ammari, Samy; Beuvon, Frederic; Mokhtari, Karima; Alentorn, Agusti; Dehais, Caroline; Houillier, Caroline; Laigle-Donadey, Florence; Psimaras, Dimitri; Carpentier, Alexandre; Cornu, Philippe; Capelle, Laurent; Mathon, Bertrand; Barnholtz-Sloan, Jill S.; Chakravarti, Arnab; Bi, Wenya L.; Frampton, Garrett M.; Sanson, Marc; Alexander, Brian M.; Cherniack, Andrew; Wen, Patrick Y.; Reardon, David A.; Marabelle, Aurelien; Park, Peter J.; Idbaih, Ahmed; Beroukhim, Rameen; Bandopadhayay, Pratiti; Bielle, Franck; Ligon, Keith L. 分享 收藏
Impact of DNA Damage Response and Repair (DDR) Gene Mutations on Efficacy of PD-(L)1 Immune Checkpoint Inhibition in Non-Small Cell Lung Cancer Ricciuti, Biagio; Recondo, Gonzalo; Spurr, Liam F.; Li, Yvonne Y.; Lamberti, Giuseppe; Venkatraman, Deepti; Umeton, Renato; Cherniack, Andrew D.; Nishino, Mizuki; Sholl, Lynette M.; Shapiro, Geoffrey, I; Awad, Mark M.; Cheng, Michael L. 分享 收藏
Molecular Mechanisms of Acquired Resistance to MET Tyrosine Kinase Inhibitors in Patients with MET Exon 14-Mutant NSCLC Recondo, Gonzalo; Bahcall, Magda; Spurr, Liam F.; Che, Jianwei; Ricciuti, Biagio; Leonardi, Giulia C.; Lo, Ying-Chun; Li, Yvonne Y.; Lamberti, Giuseppe; Nguyen, Tom; Milan, Marina S. D.; Venkatraman, Deepti; Umeton, Renato; Paweletz, Cloud P.; Albayrak, Adem; Cherniack, Andrew D.; Price, Kristin S.; Fairclough, Stephen R.; Nishino, Mizuki; Sholl, Lynette M.; Oxnard, Geoffrey R.; Janne, Pasi A.; Awad, Mark M. 分享 收藏
Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer 合并的基因组筛选将抗凋亡基因鉴定为卵巢癌化疗耐药性的靶向介质 Stover, Elizabeth H.; Baco, Maria B.; Cohen, Ofir; Li, Yvonne Y.; Christie, Elizabeth L.; Bagul, Mukta; Goodale, Amy; Lee, Yenarae; Pantel, Sasha; Rees, Matthew G.; Wei, Guo; Presser, Adam G.; Gelbard, Maya K.; Zhang, Weiqun; Zervantonakis, Ioannis K.; Bhola, Patrick D.; Ryan, Jeremy; Guerriero, Jennifer L.; Montero, Joan; Liang, Felice J.; Cherniack, Andrew D.; Piccioni, Federica; Matulonis, Ursula A.; Bowtell, David D. L.; Sarosiek, Kristopher A.; Letai, Anthony; Garraway, Levi A.; Johannessen, Cory M.; Meyerson, Matthew 分享 收藏
Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity Miret, Juan J.; Kirschmeier, Paul; Koyama, Shohei; Zhu, Mingrui; Li, Yvonne Y.; Naito, Yujiro; Wu, Min; Malladi, Venkat S.; Huang, Wei; Walker, William; Palakurthi, Sangeetha; Dranoff, Glenn; Hammerman, Peter S.; Pecot, Chad V.; Wong, Kwok-Kin; Akbay, Esra A. 分享 收藏
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