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H

Huiping Shuai

The University of Hong Kong
H指数:29
被引数:4,315

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YL1004 is a SARS-CoV-2 papain-like protease inhibitor with immunomodulatory and antiviral activity in mice

YL1004是一种SARS-CoV-2的木瓜蛋白酶样蛋白酶抑制剂，在小鼠中具有免疫调节和抗病毒活性

Nature Communications
IF15.7
2026-01-260
OA
Jinshan Nan; Huiping Shuai; Jingxin Qiao; Rui Zeng; Lianzhao Du; Yan Chen; Chaemin Yoon; Jiaheng Hu; Wenyu Guo; Lei Wang; Chong Huang; Lengjing Zhu; Yueshan Li; Shanshan Zhang; Xinyue Deng; Jingxuan Sun; Le Du; Ronggang Ma; Qiao Huang; Jian Lei; Hin Chu; Shengyong Yang
Author Correction: An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo

作者更正：一种口服可用的Mpro/TMPRSS2双特异性抑制剂，具有体内强效抗冠状病毒疗效

Nature Communications
IF15.7
2025-12-150
OAAI
Huiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
Pathogenicity, virological features, and immune evasion of SARS-CoV-2 JN.1-derived variants including JN.1.7, KP.2, KP.3, and KP.3.1.1

SARS-CoV-2 JN.1衍生变体 (包括JN.1.7、KP.2、KP.3和KP.3.1.1) 的致病性、病毒学特征和免疫逃避

Nature Communications
IF15.7
2025-12-110
OAAI
Jialu Shi; Xiaoyu Zhao; Xiaohui Jin; Jiayan Li; Yuanchen Liu; Huan Liu; Ye-Fan Hu; Zhe Chen; Yuxin Xiao; Lei Wang; Yajie Wang; Yixin He; Yue Chai; Bingjie Hu; Huiping Shuai; Yang Wang; Xiangnan Li; Shujun Jiang; Yanliang Zhang; Xiaojuan Zhang; Wan-Mui Chan; Lin-Lei Chen; Jian-Piao Cai; Baokun Sui; Honglei Zhang; Dong Yang; Longchao Zhu; Shuofeng Yuan; Jie Zhou; Jian-Dong Huang; Kwok-Yung Yuen; Kelvin Kai-Wang To; Jasper Fuk-Woo Chan; Bao-Zhong Zhang; Qiao Wang; Maozhou He; Lei Sun; Pengfei Wang; Hin Chu
An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo

一种口服可用的Mpro/TMPRSS2双特异性抑制剂，具有体内强效抗冠状病毒活性

Nature Communications
IF15.7
2025-07-160
OA
Huiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3

SARS-CoV-2 BA.2.86/JN.1和EG.5.1/HK.3的谱系特异性致病性，免疫逃逸和病毒学特征

NATURE COMMUNICATIONS
IF15.7
2024-10-091
OAAI
Liu, Yuanchen; Zhao, Xiaoyu; Shi, Jialu; Wang, Yajie; Liu, Huan; Hu, Ye-Fan; Hu, Bingjie; Shuai, Huiping; Yuen, Terrence Tsz-Tai; Chai, Yue; Liu, Feifei; Gong, Hua-Rui; Li, Jiayan; Wang, Xun; Jiang, Shujun; Zhang, Xiang; Zhang, Yanliang; Li, Xiangnan; Wang, Lei; Hartnoll, Madeline; Zhu, Tianrenzheng; Hou, Yuxin; Huang, Xiner; Yoon, Chaemin; Wang, Yang; He, Yixin; Zhou, Minmin; Du, Lianzhao; Zhang, Xiaojuan; Chan, Wan-Mui; Chen, Lin-Lei; Cai, Jian-Piao; Yuan, Shuofeng; Zhou, Jie; Huang, Jian-Dong; Yuen, Kwok-Yung; To, Kelvin Kai-Wang; Chan, Jasper Fuk-Woo; Zhang, Bao-Zhong; Sun, Lei; Wang, Pengfei; Chu, Hin
Type-II IFN inhibits SARS-CoV-2 replication in human lung epithelial cells and ex vivo human lung tissues through indoleamine 2,3-dioxygenase-mediated pathways
JOURNAL OF MEDICAL VIROLOGY
IF4.6
2024-02-192
OA
Yang, Dong; Chan, Jasper Fuk-Woo; Yoon, Chaemin; Luk, Tsz-Yat; Shuai, Huiping; Hou, Yuxin; Huang, Xiner; Hu, Bingjie; Chai, Yue; Yuen, Terrence Tsz-Tai; Liu, Yuanchen; Zhu, Tianrenzheng; Liu, Huan; Shi, Jialu; Wang, Yang; He, Yixin; Sit, Ko-Yung; Au, Wing-Kuk; Zhang, Anna Jinxia; Yuan, Shuofeng; Zhang, Bao-Zhong; Huang, Yao-Wei; Chu, Hin
Divergent trajectory of replication and intrinsic pathogenicity of SARS-CoV-2 Omicron post-BA.2/5 subvariants in the upper and lower tract

SARS-CoV-2 Omicron post-BA.2/5亚型在上下道的复制和内在致病性的不同轨迹

EBIOMEDICINE
IF10.8
2024-01-015
OAAI
Hu, Bingjie; Chan, Jasper Fuk-Woo; Liu, Yuanchen; Liu, Huan; Chen, Yan-Xia; Shuai, Huiping; Hu, Ye -Fan; Hartnoll, Madeline; Chen, Li; Xia, Yao; Hu, Jing-Chu; Yuen, Terrence Tsz-Tai; Yoon, Chaemin; Hou, Yuxin; Huang, Xiner; Chai, Yue; Zhu, Tianrenzheng; Shi, Jialu; Wang, Yang; He, Yixin; Cai, Jian-Piao; Zhou, Jie; Yuan, Shuofeng; Zhang, Jinxia; Huang, Jian-Dong; Yuen, Kwok-Yun; To, Kelvin Kai-Wang; Zhang, Bao-Zhong; Chu, Hin
The viral fitness and intrinsic pathogenicity of dominant SARS-CoV-2 Omicron sublineages BA.1, BA.2, and BA.5

优势SARS-CoV-2 Omicron亚系BA.1，BA.2和BA.5的病毒适应性和内在致病性

EBIOMEDICINE
IF10.8
2023-09-0122
OAAI
Shuai, Huiping; Chan, Jasper Fuk-Woo; Hu, Bingjie; Chai, Yue; Yoon, Chaemin; Liu, Huan; Liu, Yuanchen; Shi, Jialu; Zhu, Tianrenzheng; Hu, Jing-Chu; Hu, Ye-fan; Hou, Yuxin; Huang, Xiner; Yuen, Terrence Tsz-Tai; Wang, Yang; Zhang, Jinjin; Xia, Yao; Chen, Lin-Lei; Cai, Jian-Piao; Zhang, Anna Jinxia; Yuan, Shuofeng; Zhou, Jie; Zhang, Bao-Zhong; Huang, Jian-Dong; Yuen, Kwok-Yung; To, Kelvin Kai-Wang; Chu, Hin
Altered host protease determinants for SARS-CoV-2 Omicron
SCIENCE ADVANCES
IF12.5
2023-01-2019
OAAI
Chan, Jasper Fuk-Woo; Huang, Xiner; Hu, Bingjie; Chai, Yue; Shi, Hongyu; Zhu, Tianrenzheng; Yuen, Terrence Tsz-Tai; Liu, Yuanchen; Liu, Huan; Shi, Jialu; Wen, Lei; Shuai, Huiping; Hou, Yuxin; Yoon, Chaemin; Cai, Jian-Piao; Zhang, Anna Jinxia; Zhou, Jie; Yin, Feifei; Yuan, Shuofeng; Zhang, Bao-Zhong; Brindley, Melinda A.; Shi, Zheng-Li; Yuen, Kwok-Yung; Chu, Hin
Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2

导致SARS-CoV-2 omicron BA.1和BA.2进入偏好改变的尖峰突变

EMERGING MICROBES & INFECTIONS
IF7.5
2022-09-2860
OAAI
Hu, Bingjie; Chan, Jasper Fuk-Woo; Liu, Huan; Liu, Yuanchen; Chai, Yue; Shi, Jialu; Shuai, Huiping; Hou, Yuxin; Huang, Xiner; Yuen, Terrence Tsz-Tai; Yoon, Chaemin; Zhu, Tianrenzheng; Zhang, Jinjin; Li, Wenjun; Zhang, Anna Jinxia; Zhou, Jie; Yuan, Shuofeng; Zhang, Bao-Zhong; Yuen, Kwok-Yung; Chu, Hin
Virological features and pathogenicity of SARS-CoV-2 Omicron BA.2
CELL REPORTS MEDICINE
IF10.6
2022-09-0132
OAAI
Chan, Jasper Fuk-Woo; Hu, Bingjie; Chai, Yue; Shuai, Huiping; Liu, Huan; Shi, Jialu; Liu, Yuanchen; Yoon, Chaemin; Zhang, Jinjin; Hu, Jing-Chu; Hou, Yuxin; Huang, Xiner; Yuen, Terrence Tsz-Tai; Zhu, Tianrenzheng; Li, Wenjun; Cai, Jian-Piao; Luo, Cuiting; Yip, Cyril Chik-Yan; Zhang, Anna Jinxia; Zhou, Jie; Yuan, Shuofeng; Zhang, Bao-Zhong; Huang, Jian-Dong; Kai-Wang, Kelvin; Yuen, Kwok-Yung; Chu, Hin
Bacillus Calmette-Guerin-induced trained immunity protects against SARS-CoV-2 challenge in K18-hACE2 mice
JCI INSIGHT
IF6.1
2022-06-0837
OA
Zhang, Bao-Zhong; Shuai, Huiping; Gong, Hua-Rui; Hu, Jing-Chu; Yan, Bingpeng; Yuen, Terrence Tsz-Tai; Hu, Ye-Fan; Yoon, Chaemin; Wang, Xiao-Lei; Hou, Yuxin; Lin, Xuansheng; Huang, Xiner; Li, Renhao; Au-Yeung, Yee Man; Li, Wenjun; Hu, Bingjie; Chai, Yue; Yue, Ming; Cai, Jian-Piao; Ling, Guang Sheng; Hung, Ivan Fan-Ngai; Yuen, Kwok-Yung; Chan, Jasper Fuk-Woo; Huang, Jian-Dong; Chu, Hin
Emerging SARS-CoV-2 variants expand species tropism to murines
EBIOMEDICINE
IF10.8
2021-11-01128
OAAI
Shuai, Huiping; Chan, Jasper Fuk-Woo; Yuen, Terrence Tsz-Tai; Yoon, Chaemin; Hu, Jing-Chu; Wen, Lei; Hu, Bingjie; Yang, Dong; Wang, Yixin; Hou, Yuxin; Huang, Xiner; Chai, Yue; Chan, Chris Chung-Sing; Poon, Vincent Kwok-Man; Lu, Lu; Zhang, Rui-Qi; Chan, Wan-Mui; Ip, Jonathan Daniel; Chu, Allen Wing-Ho; Hu, Ye-Fan; Cai, Jian-Piao; Chan, Kwok-Hung; Zhou, Jie; Sridhar, Siddharth; Zhang, Bao-Zhong; Yuan, Shuofeng; Zhang, Anna Jinxia; Huang, Jian-Dong; To, Kelvin Kai-Wang; Yuen, Kwok-Yung; Chu, Hin
Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity
SCIENCE ADVANCES
IF12.5
2021-06-1867
OAAI
Chu, Hin; Shuai, Huiping; Hou, Yuxin; Zhang, Xi; Wen, Lei; Huang, Xiner; Hu, Bingjie; Yang, Dong; Wang, Yixin; Yoon, Chaemin; Wong, Bosco Ho-Yin; Li, Cun; Zhao, Xiaoyu; Poon, Vincent Kwok-Man; Cai, Jian-Piao; Wong, Kenneth Kak-Yuen; Yeung, Man-Lung; Zhou, Jie; Au-Yeung, Rex Kwok-Him; Yuan, Shuofeng; Jin, Dong-Yan; Kok, Kin-Hang; Perlman, Stanley; Chan, Jasper Fuk-Woo; Yuen, Kwok-Yung
Host and viral determinants for efficient SARS-CoV-2 infection of the human lung
NATURE COMMUNICATIONS
IF15.7
2021-01-08120
OAAI
Chu, Hin; Hu, Bingjie; Huang, Xiner; Chai, Yue; Zhou, Dongyan; Wang, Yixin; Shuai, Huiping; Yang, Dong; Hou, Yuxin; Zhang, Xi; Yuen, Terrence Tsz-Tai; Cai, Jian-Piao; Zhang, Anna Jinxia; Zhou, Jie; Yuan, Shuofeng; To, Kelvin Kai-Wang; Chan, Ivy Hau-Yee; Sit, Ko-Yung; Foo, Dominic Chi-Chung; Wong, Ian Yu-Hong; Ng, Ada Tsui-Lin; Cheung, Tan To; Law, Simon Ying-Kit; Au, Wing-Kuk; Brindley, Melinda A.; Chen, Zhiwei; Kok, Kin-Hang; Chan, Jasper Fuk-Woo; Yuen, Kwok-Yung

研究方向

暂未获取到该数据
H
Hin Chu
H 指数:61论文数:236被引数:3.1万
J
Jasper Fuk‐Woo Chan
H 指数:102论文数:680被引数:6.8万
S
Shuofeng Yuan
H 指数:49论文数:235被引数:2.6万
K
Kwok‐Yung Yuen
H 指数:161论文数:1,729被引数:16.6万
Y
Yuxin Hou
H 指数:29论文数:68被引数:4,571
J
Jie Zhou
H 指数:54论文数:217被引数:1.1万
胡丙杰 封面图
胡丙杰
H 指数:37论文数:136被引数:5,464
Y
Yue Chai
H 指数:21论文数:68被引数:2,988
T
Terrence Tsz‐Tai Yuen
H 指数:22论文数:65被引数:3,109
C
Chaemin Yoon
H 指数:18论文数:44被引数:2,688