James N. Ihle - Publications, H-index & Citations

James N. Ihle

机构信息待补充

106H指数

354论文数

4.4W被引数

收录论文 35

发表时间

Activation of Jak2 catalytic activity requires phosphorylation of Y-1007 in the kinase activation loop

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

347

OAAI

Feng, J; Witthuhn, BA; Matsuda, T; Kohlhuber, F; Kerr, IM; Ihle, JN

A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

191

OAAI

Kohlhuber, F; Rogers, NC; Watling, D; Feng, J; Guschin, D; Briscoe, J; Witthuhn, BA; Kotenko, SV; Pestka, S; Stark, GR; Ihle, JN; Kerr, IM

Gadd45γ is dispensable for normal mouse development and T-cell proliferation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Hoffmeyer, A; Piekorz, R; Moriggl, R; Ihle, JN

Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Wen, RR; Wang, DM; McKay, C; Bunting, KD; Marine, JC; Vanin, EF; Zambetti, GP; Korsmeyer, SJ; Ihle, JN; Cleveland, JL

Essential, nonredundant role for the phosphoinositide 3-kinase p110δ in signaling by the B-cell receptor complex

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

402

OAAI

Jou, ST; Carpino, N; Takahashi, Y; Piekorz, R; Chao, JR; Carpino, N; Wang, DM; Ihle, JN

Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Pelletier, Stephane; Gingras, Sebastien; Funakoshi-Tago, Megumi; Howell, Sherie; Ihle, James N.

Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

138

OAAI

Carpino, N; Thierfelder, WE; Chang, MS; Saris, C; Turner, SJ; Ziegler, SF; Ihle, JN

The centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancer

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Schuendeln, MM; Piekorz, RP; Wichmann, C; Lee, Y; McKinnon, PJ; Boyd, K; Takahashi, Y; Ihle, JN

Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Carpino, N; Kobayashi, R; Zang, H; Takahashi, Y; Jou, ST; Feng, J; Nakajima, H; Ihle, JN

Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Funakoshi-Tago, Megumi; Pelletier, Stephane; Moritake, Hiroshi; Parganas, Evan; Ihle, James N.

Chromatin condensation via the condensin II complex is required for peripheral T-cell quiescence

EMBO JOURNAL

IF8.3

2010-12-17

116

OAAI

Rawlings, Jason S.; Gatzka, Martina; Thomas, Paul G.; Ihle, James N.

Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway

CELLULAR SIGNALLING

IF3.7

2008-11-01

PREAI

Funakoshi-Tago, Megumi; Tago, Kenji; Kasahara, Tadashi; Parganas, Evan; Ihle, James N.

Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2

EMBO JOURNAL

IF8.3

2006-10-05

OAAI

Funakoshi-Tago, Megumi; Pelletier, Stephane; Matsuda, Tadashi; Parganas, Evan; Ihle, James N.

A role for STAT5A/B in protection of peripheral T-lymphocytes from postactivation apoptosis: Insights from gene expression profiling

CYTOKINE

IF3.7

2006-05-01

PREAI

Gatzka, Martina; Piekorz, Roland; Moriggl, Richard; Rawlings, Jason; Ihle, James N.

Trophoblast stem cells rescue placental defect in SOCS3-deficient mice

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2006-04-01

OAAI

Takahashi, Y; Dominici, M; Swift, J; Nagy, C; Ihle, JN

Signaling by the cytokine receptor superfamily

VIP, PACAP, AND RELATED PEPTIDES: THIRD INTERNATIONAL SYMPOSIUM

IF0

2006-02-07

100

PREAI

Ihle, JN; Thierfelder, W; Teglund, S; Stravapodis, D; Wang, DM; Feng, J; Parganas, E

Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2004-12-01

128

OAAI

Gingras, S; Parganas, E; de Pauw, A; Ihle, JN; Murray, PJ

Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2

IMMUNITY

IF26.3

2004-01-01

169

OAAI

Carpino, N; Turner, S; Mekala, D; Takahashi, Y; Zang, HS; Geiger, TL; Doherty, P; Ihle, JN

SOCS3 regulates the plasticity of gp130 signaling

NATURE IMMUNOLOGY

IF27.6

2003-05-18

418

PREAI

Lang, R; Pauleau, AL; Parganas, E; Takahashi, Y; Mages, J; Ihle, JN; Rutschman, R; Murray, PJ

Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2002-03-01

132

OAAI

Liao, HJ; Kume, T; McKay, C; Xu, MJ; Ihle, JN; Carpenter, G

研究方向