未登录 Agm1/Pgm-3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development Agm1/Pgm-3-mediated糖核苷酸合成对造血和发育至关重要 Greig, Kylle T.; Antonchuk, Jennifer; Metcalf, Donald; Morgan, Phillip O.; Krebs, Danielle L.; Zhang, Jian-Guo; Hacking, Douglas F.; Bode, Lars; Robb, Lorraine; Kranz, Christian; de Graaf, Carolyn; Bahlo, Melanie; Nicola, Nicos A.; Nutt, Stephen L.; Freeze, Hudson H.; Alexander, Warren S.; Hilton, Douglas J.; Kile, Benjamin T. 分享 收藏
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SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation Krebs, DL; Uren, RT; Metcalf, D; Rakar, S; Zhang, JG; Starr, R; De Souza, DP; Hanzinikolas, K; Eyles, J; Connolly, LM; Simpson, RJ; Nicola, NA; Nicholson, SE; Baca, M; Hilton, DJ; Alexander, WS 分享 收藏
SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function Brender, C; Columbus, R; Metcalf, D; Handman, E; Starr, R; Huntington, N; Tarlinton, D; Odum, N; Nicholson, SE; Nicola, NA; Hilton, DJ; Alexander, WS 分享 收藏
The absence of Tssc6, a member of the tetraspanin superfamily, does not affect lymphoid development but enhances in vitro T-cell proliferative responses Tarrant, JA; Groom, J; Metcalf, D; Li, RL; Borobokas, B; Wright, MD; Tarlinton, D; Robb, L 分享 收藏
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction Hildebrand, Joanne M.; Kauppi, Maria; Majewski, Ian J.; Liu, Zikou; Cox, Allison J.; Miyake, Sanae; Petrie, Emma J.; Silk, Michael A.; Li, Zhixiu; Tanzer, Maria C.; Brumatti, Gabriela; Young, Samuel N.; Hall, Cathrine; Garnish, Sarah E.; Corbin, Jason; Stutz, Michael D.; Di Rago, Ladina; Gangatirkar, Pradnya; Josefsson, Emma C.; Rigbye, Kristin; Anderton, Holly; Rickard, James A.; Tripaydonis, Anne; Sheridan, Julie; Scerri, Thomas S.; Jackson, Victoria E.; Czabotar, Peter E.; Zhang, Jian-Guo; Varghese, Leila; Allison, Cody C.; Pellegrini, Marc; Tannahill, Gillian M.; Hatchell, Esme C.; Willson, Tracy A.; Stockwell, Dina; de Graaf, Carolyn A.; Collinge, Janelle; Hilton, Adrienne; Silke, Natasha; Spall, Sukhdeep K.; Chau, Diep; Athanasopoulos, Vicki; Metcalf, Donald; Laxer, Ronald M.; Bassuk, Alexander G.; Darbro, Benjamin W.; Singh, Maria A. Fiatarone; Vlahovich, Nicole; Hughes, David; Kozlovskaia, Maria; Ascher, David B.; Warnatz, Klaus; Venhoff, Nils; Thiel, Jens; Biben, Christine; Blum, Stefan; Reveille, John; Hildebrand, Michael S.; Vinuesa, Carola G.; McCombe, Pamela; Brown, Matthew A.; Kile, Benjamin T.; McLean, Catriona; Bahlo, Melanie; Masters, Seth L.; Nakano, Hiroyasu; Ferguson, Polly J.; Murphy, James M.; Alexander, Warren S.; Silke, John 分享 收藏
Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia McKenzie, Mark D.; Ghisi, Margherita; Oxley, Ethan P.; Ngo, Steven; Cimmino, Luisa; Esnault, Cecile; Liu, Ruijie; Salmon, Jessica M.; Bell, Charles C.; Ahmed, Nouraiz; Erlichster, Michael; Witkowski, Matthew T.; Liu, Grace J.; Chopin, Michael; Dakic, Aleksandar; Simankowicz, Emilia; Pomilio, Giovanna; Vu, Tina; Krsmanovic, Pavle; Su, Shian; Tian, Luyi; Baldwin, Tracey M.; Zalcenstein, Daniela A.; DiRago, Ladina; Wang, Shu; Metcalf, Donald; Johnstone, Ricky W.; Croker, Ben A.; Lancaster, Graeme I.; Murphy, Andrew J.; Naik, Shalin H.; Nutt, Stephen L.; Pospisil, Vitek; Schroeder, Timm; Wall, Meaghan; Dawson, Mark A.; Wei, Andrew H.; de The, Hugues; Ritchie, Matthew E.; Zuber, Johannes; Dickins, Ross A. 分享 收藏
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IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome Murphy, Andrew J.; Kraakman, Michael J.; Kammoun, Helene L.; Dragoljevic, Dragana; Lee, Man K. S.; Lawlor, Kate E.; Wentworth, John M.; Vasanthakumar, Ajithkumar; Gerlic, Motti; Whitehead, Lachlan W.; DiRago, Ladina; Cengia, Louise; Lane, Rachael M.; Metcalf, Donald; Vince, James E.; Harrison, Leonard C.; Kallies, Axel; Kile, Benjamin T.; Croker, Ben A.; Febbraio, Mark A.; Masters, Seth L. 分享 收藏
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β Kim, Man Lyang; Chae, Jae Jin; Park, Yong Hwan; De Nardo, Dominic; Stirzaker, Roslynn A.; Ko, Hyun-Ja; Tye, Hazel; Cengia, Louise; DiRago, Ladina; Metcalf, Donald; Roberts, Andrew W.; Kastner, Daniel L.; Lew, Andrew M.; Lyras, Dena; Kile, Benjamin T.; Croker, Ben A.; Masters, Seth L. 分享 收藏
Early Lineage Priming by Trisomy of Erg Leads to Myeloproliferation in a Down Syndrome Model Ng, Ashley P.; Hu, Yifang; Metcalf, Donald; Hyland, Craig D.; Ierino, Helen; Phipson, Belinda; Wu, Di; Baldwin, Tracey M.; Kauppi, Maria; Kiu, Hiu; Di Rago, Ladina; Hilton, Douglas J.; Smyth, Gordon K.; Alexander, Warren S. 分享 收藏
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation (vol 96, pg 2071, 1999) Zhang, Jian-Guo; Farley, Alison; Nicholson, Sandra E.; Willson, Tracy A.; Zugaro, Lisa M.; Simpson, Richard J.; Moritz, Robert L.; Cary, Dale; Richardson, Rachael; Hausmann, George; Kile, Benjamin T.; Kent, Stephen B. H.; Alexander, Warren S.; Metcalf, Donald; Hilton, Douglas J.; Nicola, Nicos A.; Baca, Manuel 分享 收藏
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A reporter mouse reveals lineage-specific and heterogeneous expression of IRF8 during lymphoid and myeloid cell differentiation (vol 193, pg 1766, 2014) Wang, Hongsheng; Yan, Ming; Sun, Jiafang; Jain, Shweta; Yoshimi, Ryusuke; Abolfath, Sanaz Momben; Ozato, Keiko; Coleman, William G., Jr.; Ng, Ashley P.; Metcalf, Donald; DiRago, Ladina; Nutt, Stephen L.; Morse, Herbert C., III 分享 收藏
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A Reporter Mouse Reveals Lineage-Specific and Heterogeneous Expression of IRF8 during Lymphoid and Myeloid Cell Differentiation Wang, Hongsheng; Yan, Ming; Sun, Jiafang; Jain, Shweta; Yoshimi, Ryusuke; Abolfath, Sanaz Momben; Ozato, Keiko; Coleman, William G., Jr.; Ng, Ashley P.; Metcalf, Donald; DiRago, Ladina; Nutt, Stephen L.; Morse, Herbert C., III 分享 收藏
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Suppressor of Cytokine Signaling 4 (SOCS4) Protects against Severe Cytokine Storm and Enhances Viral Clearance during Influenza Infection 细胞因子信号转导抑制因子4 (SOCS4) 可防止严重的细胞因子风暴并增强流感感染期间的病毒清除 Kedzierski, Lukasz; Linossi, Edmond M.; Kolesnik, Tatiana B.; Day, E. Bridie; Bird, Nicola L.; Kile, Benjamin T.; Belz, Gabrielle T.; Metcalf, Donald; Nicola, Nicos A.; Kedzierska, Katherine; Nicholson, Sandra E. 分享 收藏
Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation Ng, Ashley P.; Kauppi, Maria; Metcalf, Donald; Hyland, Craig D.; Josefsson, Emma C.; Lebois, Marion; Zhang, Jian-Guo; Baldwin, Tracey M.; Di Rago, Ladina; Hilton, Douglas J.; Alexander, Warren S. 分享 收藏
Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways Josefsson, Emma C.; Burnett, Deborah L.; Lebois, Marion; Debrincat, Marlyse A.; White, Michael J.; Henley, Katya J.; Lane, Rachael M.; Moujalled, Diane; Preston, Simon P.; O'Reilly, Lorraine A.; Pellegrini, Marc; Metcalf, Donald; Strasser, Andreas; Kile, Benjamin T. 分享 收藏
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