Sabine Heijhuurs - Publications, H-index & Citations

Sabine Heijhuurs

Utrecht University

10H指数

38论文数

697被引数

收录论文 12

发表时间

Cis- and trans-binding chimeric costimulatory receptors enhance T-cell fitness and tumor control 顺式和反式结合嵌合共刺激受体增强T细胞适应性和肿瘤控制

Cellular & Molecular Immunology

IF19.8

2025-12-10

PREAI

Patricia Hernández-López; Caterina Riillo; Laia Gasull-Celades; Jairo G. E. Lommen; Sabine Heijhuurs; Jiali Zheng; Sascha van Bruggen; Marina Zintchenko; Simon M. Brandl; Susana Minguet; Jürgen Kuball; Dennis X. Beringer

Mapping T cell dynamics to molecular profiles through behavior-guided transcriptomics 通过行为引导转录组学将T细胞动态映射到分子谱中

NATURE PROTOCOLS

IF16

2025-02-10

PREAI

Wezenaar, A. K. L.; Pandey, U.; Keramati, F.; Hernandez-Roca, M.; Brazda, P.; Roman, M. Barrera; Cleven, A.; Karaiskaki, F.; Aarts-Riemens, T.; de Blank, S.; Hernandez-Lopez, P.; Heijhuurs, S.; Alemany, A.; Kuball, J.; Sebestyen, Z.; Dekkers, J. F.; Stunnenberg, H. G.; Alieva, M.

Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells 癌症代谢组和应激抗原的双重靶向影响工程化T细胞的转录组异质性和功效

NATURE IMMUNOLOGY

IF27.6

2023-11-27

PREAI

Hernandez-Lopez, Patricia; van Diest, Eline; Brazda, Peter; Heijhuurs, Sabine; Meringa, Angelo; van Heyningen, Lauren Hoorens; Riillo, Caterina; Schwenzel, Caroline; Zintchenko, Marina; Johanna, Inez; Nicolasen, Mara J. T.; Cleven, Astrid; Kluiver, Thomas A.; Millen, Rosemary; Zheng, Jiali; Karaiskaki, Froso; Straetemans, Trudy; Clevers, Hans; de Bree, Remco; Stunnenberg, Hendrik G.; Peng, Weng Chuan; Roodhart, Jeanine; Minguet, Susana; Sebestyen, Zsolt; Beringer, Dennis X.; Kuball, Jurgen

Gamma delta TCR anti-CD3 bispecific molecules (GABs) as novel immunotherapeutic compounds

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2021-11-23

OAAI

van Diest, Eline; Hernandez Lopez, Patricia; Meringa, Angelo D.; Vyborova, Anna; Karaiskaki, Froso; Heijhuurs, Sabine; Gumathi Bormin, Jan; van Dooremalen, Sanne; Nicolasen, Mara J. T.; Gatti, Lucrezia C. D. E.; Johanna, Inez; Straetemans, Trudy; Sebestyen, Zsolt; Beringer, Dennis X.; Kuball, Jurgen

Adding Help to an HLA-A*24:02 Tumor-Reactive γδTCR Increases Tumor Control

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-10-25

OAAI

Johanna, Inez; Hernandez-Lopez, Patricia; Heijhuurs, Sabine; Scheper, Wouter; Bongiovanni, Laura; de Bruin, Alain; Beringer, Dennis X.; Oostvogels, Rimke; Straetemans, Trudy; Sebestyen, Zsolt; Kuball, Juergen

TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2020-02-05

OAAI

Johanna, Inez; Hernandez-Lopez, Patricia; Heijhuurs, Sabine; Bongiovanni, Laura; de Bruin, Alain; Beringer, Dennis; van Dooremalen, Sanne; Shultz, Leonard D.; Ishikawa, Fumihiko; Sebestyen, Zsolt; Straetemans, Trudy; Kuball, Jurgen

Identification of a tumor-specific allo-HLA-restricted γδTCR

BLOOD ADVANCES

IF7.1

2019-10-04

OAAI

Kierkels, G. J. J.; Scheper, W.; Meringa, A. D.; Johanna, I; Beringer, D. X.; Janssen, A.; Schiffler, M.; Aarts-Riemens, T.; Kramer, L.; Straetemans, T.; Heijhuurs, S.; Leusen, J. H. W.; San Jose, E.; Fuchs, K.; Griffioen, M.; Falkenburg, J. H.; Bongiovanni, L.; de Bruin, A.; Vargas-Diaz, D.; Altelaar, M.; Heck, A. J. R.; Shultz, L. D.; Ishikawa, F.; Nishimura, M., I; Sebestyen, Z.; Kuball, J.

Evaluating in vivo efficacy - toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2019-03-12

OAAI

Johanna, Inez; Straetemans, Trudy; Heijhuurs, Sabine; Aarts-Riemens, Tineke; Norell, Hakan; Bongiovanni, Laura; de Bruin, Alain; Sebestyen, Zsolt; Kuball, Jurgen

Targeting solid malignancies with TEGs: αβT cells engineered to express a defined γδTCR in xenograft mice model

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Johanna, Inez; Straetemans, Trudy; Heijhuurs, Sabine; Jansen, Koen; van Rheenen, Jacco; Drost, Jarno; Sebestyen, Zsolt; Kuball, Jurgen

GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR

FRONTIERS IN IMMUNOLOGY

IF5.9

2018-05-30

OAAI

Straetemans, Trudy; Kierkels, Guido J. J.; Doorn, Ruud; Jansen, Koen; Heijhuurs, Sabine; dos Santos, Joao M.; van Muyden, Anna D. D.; Vie, Henri; Clemenceau, Beatrice; Raymakers, Reinier; de Witte, Moniek; Sebestyen, Zsolt; Kuball, Jurgen

Untouched GMP-Ready Purified Engineered Immune Cells to Treat Cancer

CLINICAL CANCER RESEARCH

IF10.2

2015-08-31

OAAI

Straetemans, Trudy; Grunder, Cordula; Heijhuurs, Sabine; Hol, Samantha; Slaper-Cortenbach, Ineke; Boenig, Halvard; Sebestyen, Zsolt; Kuball, Jurgen

γδT cells elicited by CMV reactivation after allo-SCT cross-recognize CMV and leukemia

LEUKEMIA

IF13.4

2013-01-01

158

PREAI

Scheper, W.; van Dorp, S.; Kersting, S.; Pietersma, F.; Lindemans, C.; Hol, S.; Heijhuurs, S.; Sebestyen, Z.; Grunder, C.; Marcu-Malina, V.; Marchant, A.; Donner, C.; Plachter, B.; Vermijlen, D.; van Baarle, D.; Kuball, J.

研究方向